EP0856298B1 - Filler pipe for biological liquid containers, in particular for artificial insemination - Google Patents

Filler pipe for biological liquid containers, in particular for artificial insemination Download PDF

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Publication number
EP0856298B1
EP0856298B1 EP19980400189 EP98400189A EP0856298B1 EP 0856298 B1 EP0856298 B1 EP 0856298B1 EP 19980400189 EP19980400189 EP 19980400189 EP 98400189 A EP98400189 A EP 98400189A EP 0856298 B1 EP0856298 B1 EP 0856298B1
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EP
European Patent Office
Prior art keywords
conical part
filler nozzle
nozzle according
filling
straw
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP19980400189
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German (de)
French (fr)
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EP0856298A1 (en
Inventor
Jean-Gérard Saint-Ramon
Christian Beau
Alain Ehrsam
Thierry Louviot
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IMV Technologies SA
Original Assignee
IMV Technologies SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IMV Technologies SA filed Critical IMV Technologies SA
Publication of EP0856298A1 publication Critical patent/EP0856298A1/en
Application granted granted Critical
Publication of EP0856298B1 publication Critical patent/EP0856298B1/en
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Expired - Lifetime legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D19/00Instruments or methods for reproduction or fertilisation
    • A61D19/02Instruments or methods for reproduction or fertilisation for artificial insemination
    • A61D19/022Containers for animal semen, e.g. pouches or vials ; Methods or apparatus for treating or handling animal semen containers, e.g. filling or closing
    • A61D19/024Tube-like containers, e.g. straws
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/0275Interchangeable or disposable dispensing tips

Definitions

  • the present invention relates to a filling nozzle (or fitting) for elements for packaging volumes of seminal fluid or any other product biological, such as for example flakes, cannulas, tubes and catheters.
  • Sequins are tubular tanks of animal semen intended for artificial insemination or conditioning of biological fluids, the internal diameter is in particular sufficiently small to allow the maintenance in place the dose by capillary action alone, which simplifies handling in the event that the straw should be used as soon as it is filled, without intermediate storage.
  • Existing filling tips or fittings are more particularly intended for filling devices such as flasks, beakers, bottles, etc., but are not suitable for filling tubes, flakes, cannulas, catheters, especially if you wish to leave an area free of any contamination of the filling product, in the case, for example, of closing by welding.
  • Patent FR-B-2 680 101 describes disposable and recoverable nozzles used for filling the flakes.
  • such devices are not suitable for a unitary filling mode, that is to say a few flakes, or automated, that is to say several flakes without manual replacement of the nozzle.
  • US-A-3,343,539 describes a syringe for artificial insemination in which a tube is removably connected to the body, the tube being intended to be disassociated from it.
  • the syringe of this patent is not suitable for filling of glitter and cannot avoid pollution in the closed area of the sparkling.
  • EP-0 701 865 describes a pipette filling tip. This tip does not have air inlet allowing air entry at the time of the pipetting of the pipette of the nozzle and is not adapted to the filling of flakes either.
  • FR-1-2 651 793 describes tubes and flakes for preservation cryogenic biological samples and a method of filling such tubes and flakes.
  • the filling device used does not provide guidance for the straw and does not avoid pollution in the area where the straw is closed.
  • Another object of the invention is to provide a filling nozzle avoiding pollution in the glitter closure area. Another object of the invention is to provide a filling nozzle. compatible with automatic placement, for example with an automatic filling, or with manual handling (unit filling).
  • the present invention provides a nozzle or fitting responding to objects above, characterized in that it consists of a material body plastic with a conical part, male or female, surrounding partially a capillary tube.
  • the conical part of the plastic body allows crimping of a sequin.
  • the capillary tube is preferably made of a material chosen from stainless steel and plastics.
  • the tip advantageously comprises a cylindrical part in the extension of said female conical part.
  • said plastic body comprises an input means air, for example a vent or a plurality of channels.
  • the male conical part advantageously has a double taper.
  • the nozzle or fitting of the present invention consists of a body made of plastic 1 surrounding a capillary tube 2.
  • the capillary tube 2 is for example made of stainless steel or of material plastic.
  • the tip has a truncated cone shape 3, a cylindrical shape 4 and a air inlet means 6.
  • the cylindrical shape 4 allows the guiding of the straw 7 (shown on the Figures 2, 4 and 7 with its plug 7 ') during assembly and extraction, allowing thus to avoid any contact with the capillary and the internal face of the straw so remove any contamination from the liquid in the closing area 5.
  • the air inlet means 6 authorizes the entry of air at the time of the trimming of the glitter 7 of the cone 3 to guarantee the unsullied area.
  • the air inlet means 6 can be perpendicular or inclined with respect to the longitudinal axis of the nozzle.
  • the air inlet means 6 can be a vent ( Figures 1 to 3) or it can be consisting of one or more 6 'channels.
  • the plastic body 1 can be molded onto the capillary tube 2.
  • the plastic body 1 can also be injected and the capillary tube 2 press fit.
  • the tightness is obtained by the adjustment and the length of fitting or gluing.
  • the plastic body 1 can also be machined.
  • FIG. 6 Another variant of the filling nozzle or fitting of this invention, shown in Figures 6 to 8, is made from a 3 'male cone (and no longer female).
  • This cone can be double tapered (part 8) to allow the air inlet at the time of the sequencing of the straw 7 to guarantee the zone of closure 5 not soiled.
  • it is necessary to use a tool of guide 9 to serve the flake 7 of the cone 3 '(in the direction of the arrows F) without capillary tube 2 does not come into contact with the interior wall of the straw and stains the closing area 5.
  • FIG. 9 Yet another variant of the nozzle or filling connection of the present invention, shown in Figure 9 is that it is made in two parts.
  • the filling and closing of a straw are carried out in a known manner, the end 2a of the capillary tube 2 being immersed in the biological product of which wishes to fill the straw, and the end 7b of the straw 7 being connected to a source of depression.
  • the closure of the straw is carried out in a manner known per se.
  • Those skilled in the art may refer in this regard to FR-B-2 680 101 cited above.

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Reproductive Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Supply Of Fluid Materials To The Packaging Location (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Description

La présente invention concerne un embout (ou raccord) de remplissage pour éléments de conditionnement de volumes de liquide séminal ou de tout autre produit biologique, tels par exemple les paillettes, les canules, les tubes et les cathéters.The present invention relates to a filling nozzle (or fitting) for elements for packaging volumes of seminal fluid or any other product biological, such as for example flakes, cannulas, tubes and catheters.

Les paillettes sont des réservoirs tubulaires de semence animale destinées à l'insémination artificielle ou au conditionnement de liquides biologiques, dont le diamètre intérieur est en particulier suffisamment faible pour permettre le maintien en place de la dose par seule capillarité, ce qui simplifie la manipulation dans le cas où la paillette doit être utilisée dès son remplissage, sans stockage intermédiaire.Sequins are tubular tanks of animal semen intended for artificial insemination or conditioning of biological fluids, the internal diameter is in particular sufficiently small to allow the maintenance in place the dose by capillary action alone, which simplifies handling in the event that the straw should be used as soon as it is filled, without intermediate storage.

Les embouts ou raccords de remplissage existants sont plus particulièrement destinés au remplissage de dispositifs du type flacons, béchers, bouteilles, etc., mais ne sont pas adaptés au remplissage de tubes, paillettes, canules, cathéters, surtout si on désire laisser une zone exempte de toute souillure de produit de remplissage, dans le cas par exemple d'une fermeture par soudage.Existing filling tips or fittings are more particularly intended for filling devices such as flasks, beakers, bottles, etc., but are not suitable for filling tubes, flakes, cannulas, catheters, especially if you wish to leave an area free of any contamination of the filling product, in the case, for example, of closing by welding.

Ces embouts ou raccords sont du type cônes ou aiguilles.These ends or fittings are of the cone or needle type.

Le brevet FR-B-2 680 101 décrit des buses jetables et récupérables utilisées pour le remplissage des paillettes. Toutefois, de tels dispositifs ne sont pas adaptés à un mode de remplissage unitaire, c'est-à-dire de quelques paillettes, ou automatisé, c'est-à-dire plusieurs paillettes sans remplacement manuel de la buse.Patent FR-B-2 680 101 describes disposable and recoverable nozzles used for filling the flakes. However, such devices are not suitable for a unitary filling mode, that is to say a few flakes, or automated, that is to say several flakes without manual replacement of the nozzle.

US-A-3 343 539 décrit une seringue pour l'insémination artificielle dans laquelle un tube est relié de façon amovible au corps, le tube étant destiné à être désolidarisé de celui-ci. La seringue de ce brevet n'est pas adaptée au remplissage de paillettes et ne saurait éviter une pollution dans la zone de fermeture de la paillette.US-A-3,343,539 describes a syringe for artificial insemination in which a tube is removably connected to the body, the tube being intended to be disassociated from it. The syringe of this patent is not suitable for filling of glitter and cannot avoid pollution in the closed area of the sparkling.

EP-0 701 865 décrit un embout de remplissage de pipette. Cet embout ne comporte pas d'entrée d'air permettant une entrée d'air au moment du dessertissage de la pipette de l'embout et n'est pas non plus adapté au remplissage de paillettes.EP-0 701 865 describes a pipette filling tip. This tip does not have air inlet allowing air entry at the time of the pipetting of the pipette of the nozzle and is not adapted to the filling of flakes either.

FR-1-2 651 793 décrit des tubes et des paillettes pour la conservation cryogénique d'échantillons biologiques et un procédé de remplissage de tels tubes et paillettes. Le dispositif de remplissage utilisé ne fournit pas de guidage de la paillette et n'évite pas une pollution dans la zone de fermeture de la paillette.FR-1-2 651 793 describes tubes and flakes for preservation cryogenic biological samples and a method of filling such tubes and flakes. The filling device used does not provide guidance for the straw and does not avoid pollution in the area where the straw is closed.

Un autre objet de l'invention est de fournir un embout de remplissage évitant une pollution dans la zone de fermeture de la paillette. Un objet de l'invention est encore de fournir un embout de remplissage compatible avec un placement automatique, par exemple avec un automate de remplissage, ou avec une manipulation manuelle (remplissage unitaire). Another object of the invention is to provide a filling nozzle avoiding pollution in the glitter closure area. Another object of the invention is to provide a filling nozzle. compatible with automatic placement, for example with an automatic filling, or with manual handling (unit filling).

La présente invention fournit un embout ou raccord répondant aux objets ci-dessus, caractérisé en ce qu'il est constitué d'un corps en matière plastique présentant une partie conique, de forme mâle ou femelle, entourant partiellement un tube capillaire. La partie conique du corps en matière plastique permet le sertissage d'une paillette.The present invention provides a nozzle or fitting responding to objects above, characterized in that it consists of a material body plastic with a conical part, male or female, surrounding partially a capillary tube. The conical part of the plastic body allows crimping of a sequin.

Le tube capillaire est de préférence fabriqué en un matériau choisi parmi l'acier inoxydable et les matières plastiques.The capillary tube is preferably made of a material chosen from stainless steel and plastics.

Dans le cas d'une forme conique femelle de la partie conique du corps en matière plastique, l'embout comprend avantageusement une partie cylindrique dans le prolongement de ladite partie conique femelle. In the case of a female conical shape of the conical part of the body in plastic material, the tip advantageously comprises a cylindrical part in the extension of said female conical part.

Toujours dans le cas d'une forme conique femelle de la partie conique du corps en matière plastique, ledit corps en matière plastique comprend un moyen d'entrée d'air, par exemple un évent ou une pluralité de canaux.Always in the case of a female conical shape of the conical part of the body made of plastic, said plastic body comprises an input means air, for example a vent or a plurality of channels.

Dans le cas d'une forme conique mâle de la partie conique du corps en matière plastique, la partie conique mâle présente avantageusement une double conicité.In the case of a male conical shape of the conical part of the material body plastic, the male conical part advantageously has a double taper.

L'invention sera mieux comprise en référence aux dessins annexés dans lesquels :

  • la Figure 1 est une vue en coupe selon son axe longitudinal d'un embout ou raccord selon la présente invention;
  • la Figure 2 est une vue en coupe selon son axe longitudinal de l'embout de la Figure 1 dans lequel une paillette est venue se sertir;
  • la Figure 3 est une vue en coupe selon son axe longitudinal de l'embout de la Figure 1 dans lequel une paillette est venue se dessertir;
  • la Figure 4 est une vue en coupe selon son axe longitudinal d'encore un autre mode de réalisation de l'embout de la présente invention dans lequel une paillette est venue se sertir;
  • la Figure 5 est une vue en coupe selon son axe transversal de l'embout de la Figure 4;
  • la Figure 6 est une vue en coupe selon son axe longitudinal d'une autre variante de l'embout de la présente invention;
  • les Figures 7 et 8 sont des vues en coupe selon son axe longitudinal d'une autre variante de l'embout de la présente invention dans lequel une paillette est venue se sertir;
  • la Figure 9 est une vue en coupe selon son axe longitudinal d'un autre embout selon l'invention;
  • la Figure 10 est une vue éclatée en coupe selon son axe longitudinal de l'embout de la Figure 9.
The invention will be better understood with reference to the accompanying drawings in which:
  • Figure 1 is a sectional view along its longitudinal axis of a nozzle or fitting according to the present invention;
  • Figure 2 is a sectional view along its longitudinal axis of the tip of Figure 1 in which a flake is crimped;
  • Figure 3 is a sectional view along its longitudinal axis of the tip of Figure 1 in which a flake has come to disrupt;
  • Figure 4 is a sectional view along its longitudinal axis of yet another embodiment of the tip of the present invention in which a flake is crimped;
  • Figure 5 is a sectional view along its transverse axis of the tip of Figure 4;
  • Figure 6 is a sectional view along its longitudinal axis of another variant of the nozzle of the present invention;
  • Figures 7 and 8 are sectional views along its longitudinal axis of another variant of the nozzle of the present invention in which a flake is crimped;
  • Figure 9 is a sectional view along its longitudinal axis of another tip according to the invention;
  • FIG. 10 is an exploded view in section along its longitudinal axis of the nozzle of FIG. 9.

L'embout ou raccord de la présente invention est constitué d'un corps en matière plastique 1 entourant un tube capillaire 2.The nozzle or fitting of the present invention consists of a body made of plastic 1 surrounding a capillary tube 2.

Le tube capillaire 2 est par exemple en acier inoxydable ou en matière plastique.The capillary tube 2 is for example made of stainless steel or of material plastic.

L'embout présente une forme en tronc de cône 3, une forme cylindrique 4 et un moyen d'entrée d'air 6.The tip has a truncated cone shape 3, a cylindrical shape 4 and a air inlet means 6.

La forme cylindrique 4 permet le guidage de la paillette 7 (représentée sur les Figures 2, 4 et 7 avec son bouchon 7') au montage et à l'extraction, en permettant ainsi d'éviter tout contact avec le capillaire et la face interne de la paillette de manière à supprimer toute souillure venant du liquide dans la zone de fermeture 5.The cylindrical shape 4 allows the guiding of the straw 7 (shown on the Figures 2, 4 and 7 with its plug 7 ') during assembly and extraction, allowing thus to avoid any contact with the capillary and the internal face of the straw so remove any contamination from the liquid in the closing area 5.

Le moyen d'entrée d'air 6 autorise l'entrée d'air au moment du dessertissage de la paillette 7 du cône 3 pour garantir la zone non souillée. Le moyen d'entrée d'air 6 peut être perpendiculaire ou incliné par rapport à l'axe longitudinal de l'embout.The air inlet means 6 authorizes the entry of air at the time of the trimming of the glitter 7 of the cone 3 to guarantee the unsullied area. The air inlet means 6 can be perpendicular or inclined with respect to the longitudinal axis of the nozzle.

Le moyen d'entrée d'air 6 peut être un évent (Figures 1 à 3) ou bien il peut être constitué de un ou plusieurs canaux 6'.The air inlet means 6 can be a vent (Figures 1 to 3) or it can be consisting of one or more 6 'channels.

Le corps en matière plastique 1 peut être surmoulé sur le tube capillaire 2.The plastic body 1 can be molded onto the capillary tube 2.

Le corps en matière plastique 1 peut également être injecté et le tube capillaire 2 emmanché à force. L'étanchéité est obtenue par l'ajustement et la longueur de l'emmanchement ou par collage.The plastic body 1 can also be injected and the capillary tube 2 press fit. The tightness is obtained by the adjustment and the length of fitting or gluing.

Le corps en matière plastique 1 peut aussi être usiné.The plastic body 1 can also be machined.

Une autre variante de l'embout ou raccord de remplissage de la présente invention, représentée sur les Figures 6 à 8, est réalisée à partir d'un cône mâle 3' (et non plus femelle). Ce cône peut être à double conicité (partie 8) pour permettre l'entrée de l'air au moment du dessertissage de la paillette 7 pour garantir la zone de fermeture 5 non souillée. Dans ce cas il est nécessaire d'utiliser un outillage de guidage 9 pour dessertir la paillette 7 du cône 3' (dans le sens des flèches F) sans que le tube capillaire 2 ne vienne en contact avec la paroi intérieure de la paillette et souille la zone de fermeture 5.Another variant of the filling nozzle or fitting of this invention, shown in Figures 6 to 8, is made from a 3 'male cone (and no longer female). This cone can be double tapered (part 8) to allow the air inlet at the time of the sequencing of the straw 7 to guarantee the zone of closure 5 not soiled. In this case it is necessary to use a tool of guide 9 to serve the flake 7 of the cone 3 '(in the direction of the arrows F) without capillary tube 2 does not come into contact with the interior wall of the straw and stains the closing area 5.

Encore une autre variante de l'embout ou raccord de remplissage de la présente invention, représentée sur la Figure 9 est qu'il est réalisé en deux parties.Yet another variant of the nozzle or filling connection of the present invention, shown in Figure 9 is that it is made in two parts.

Le remplissage et la fermeture d'une paillette sont effectués de façon connue, l'extrémité 2a du tube capillaire 2 étant immergée dans le produit biologique dont on désire remplir la paillette, et l'extrémité 7b de la paillette 7 étant reliée à une source de dépression. La fermeture de la paillette est effectuée de façon connue en soi. L'homme de l'art pourra se référer à cet égard au FR-B-2 680 101 cité plus haut.The filling and closing of a straw are carried out in a known manner, the end 2a of the capillary tube 2 being immersed in the biological product of which wishes to fill the straw, and the end 7b of the straw 7 being connected to a source of depression. The closure of the straw is carried out in a manner known per se. Those skilled in the art may refer in this regard to FR-B-2 680 101 cited above.

L'homme de l'art comprendra que bien que l'invention ait été décrite et illustrée pour des modes de réalisation particuliers, de nombreuses variantes peuvent être envisagées tout en restant dans le cadre de l'invention tel que défini dans les revendications annexées.Those skilled in the art will understand that although the invention has been described and illustrated for particular embodiments, many variants can be envisaged while remaining within the framework of the invention as defined in the appended claims.

Claims (9)

  1. A filler nozzle for straws consisting of a capillary tube (2) and a plastics material body (1) characterized in that said body has a conical part (3, 3') partly surrounding the length of said capillary tube (2) and enabling a straw to be inserted and gripped, and in that said plastics material body (1) includes air entry means enabling air to enter when said straw is released from said conical part (3, 3').
  2. A filler nozzle according to claim 1 characterized in that the capillary tube (2) is made from a material selected from the group comprising stainless steel and plastics materials.
  3. A filler nozzle according to claims 1 and 2 characterized in that the conical part is a female conical part (3).
  4. A filler nozzle according to claim 3 characterized in that it further comprises a cylindrical part (4) aligned with the female conical part (3).
  5. A filler nozzle according to any of claims 1 to 4 characterized in that the air entry means consist in a vent (6).
  6. A filler nozzle according to any of claims 1 to 4 characterized in that the air entry means consist in a passage or a plurality of passages (6').
  7. A filler nozzle according to either claim 1 or claim 2 characterized in that the conical part is a male conical part (3').
  8. A filler nozzle according to claim 7 characterized in that the conical part (3') comprises two cones.
  9. A filler nozzle according to either claim 7 or claim 8 characterized in that it is made in two parts.
EP19980400189 1997-01-31 1998-01-29 Filler pipe for biological liquid containers, in particular for artificial insemination Expired - Lifetime EP0856298B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9701064A FR2758973B1 (en) 1997-01-31 1997-01-31 FILLING TIP FOR BIOLOGICAL LIQUID PACKAGING ELEMENTS, IN PARTICULAR FOR ARTIFICIAL INSEMINATION
FR9701064 1997-01-31

Publications (2)

Publication Number Publication Date
EP0856298A1 EP0856298A1 (en) 1998-08-05
EP0856298B1 true EP0856298B1 (en) 2003-04-09

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
EP19980400189 Expired - Lifetime EP0856298B1 (en) 1997-01-31 1998-01-29 Filler pipe for biological liquid containers, in particular for artificial insemination

Country Status (5)

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EP (1) EP0856298B1 (en)
DE (1) DE69813056T2 (en)
DK (1) DK0856298T3 (en)
ES (1) ES2191910T3 (en)
FR (1) FR2758973B1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2886931B1 (en) 2005-06-14 2007-08-17 Cryo Bio System Sa PROCESS FOR CONDITIONING A PREDETERMINED DOSE OF LIQUID SUBSTANCE IN A STRAIN AND DEVICE FOR IMPLEMENTING THE SAME
FR3036947B1 (en) * 2015-06-02 2017-05-26 Imv Tech DEVICE FOR FILLING GLITTERS AND MACHINE COMPRISING SAME

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3343539A (en) * 1964-10-22 1967-09-26 Moorhouse Turkey Hatchery Inc Piston type artificial insemination syringe having stroke adjusting means
FR2609885B1 (en) * 1987-01-22 1989-04-14 Cassou Robert INSTRUMENT FOR ARTIFICIAL INSEMINATION, TRANSFER OF EMBRYOS OR COLLECTION OF FOLLICULAR LIQUIDS FROM MAMMALS
FR2651793B1 (en) * 1989-09-14 1991-12-06 Cassou Robert TUBES OR SEQUINS FOR THE CRYOGENIC PRESERVATION OF BIOLOGICAL SAMPLES SUCH AS VIRUSES, AND FILLING METHOD.
JP3387649B2 (en) * 1994-09-16 2003-03-17 富士写真フイルム株式会社 Spotted tip

Also Published As

Publication number Publication date
EP0856298A1 (en) 1998-08-05
DE69813056T2 (en) 2003-10-23
DK0856298T3 (en) 2003-04-28
FR2758973A1 (en) 1998-08-07
DE69813056D1 (en) 2003-05-15
ES2191910T3 (en) 2003-09-16
FR2758973B1 (en) 1999-06-11

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