EP0829341A3 - Method and machine for producing tablets of medicinal powder - Google Patents

Method and machine for producing tablets of medicinal powder Download PDF

Info

Publication number
EP0829341A3
EP0829341A3 EP97102534A EP97102534A EP0829341A3 EP 0829341 A3 EP0829341 A3 EP 0829341A3 EP 97102534 A EP97102534 A EP 97102534A EP 97102534 A EP97102534 A EP 97102534A EP 0829341 A3 EP0829341 A3 EP 0829341A3
Authority
EP
European Patent Office
Prior art keywords
medicinal powder
tablets
machine
quantities
vessel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP97102534A
Other languages
German (de)
French (fr)
Other versions
EP0829341A2 (en
Inventor
Angelo Ansalino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MG 2 SpA
MG2 SpA
Biovail Technologies Ltd
Original Assignee
MG 2 SpA
MG2 SpA
Fuisz Technologies Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MG 2 SpA, MG2 SpA, Fuisz Technologies Ltd filed Critical MG 2 SpA
Publication of EP0829341A2 publication Critical patent/EP0829341A2/en
Publication of EP0829341A3 publication Critical patent/EP0829341A3/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/10Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B30PRESSES
    • B30BPRESSES IN GENERAL
    • B30B11/00Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/02Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
    • B30B11/027Particular press methods or systems
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B30PRESSES
    • B30BPRESSES IN GENERAL
    • B30B15/00Details of, or accessories for, presses; Auxiliary measures in connection with pressing
    • B30B15/30Feeding material to presses
    • B30B15/302Feeding material in particulate or plastic state to moulding presses
    • B30B15/304Feeding material in particulate or plastic state to moulding presses by using feed frames or shoes with relative movement with regard to the mould or moulds

Landscapes

  • Health & Medical Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Basic Packing Technique (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

A method and machine (1) for producing tablets (9) of medicinal powder (3); the method including, for each cycle, the steps of withdrawing a number of quantities of medicinal powder (3) from a vessel (10) by means of a metering device (21), compressing the quantities of medicinal powder (3) to form respective tablets (9) of medicinal powder (3), and, finally, depositing the tablets (9) of compressed medicinal powder (3) inside containers (7) by which they are preserved; the compression step including a precompression step wherein a die forming device (21) compresses the quantities of medicinal powder (3) inside the vessel (10) to preform the tablets (9), and a compacting step wherein the die forming device (21) compresses the preformed tablets (9) on a horizontal plate (50) located outside the vessel (10) and having a number of dies (53) for imparting a given form to the tablets (9).
EP97102534A 1996-09-11 1997-02-17 Method and machine for producing tablets of medicinal powder Withdrawn EP0829341A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITBO960453 1996-09-11
IT96BO000453A IT1286212B1 (en) 1996-09-11 1996-09-11 METHOD AND MACHINE FOR THE PRODUCTION OF MEDICINAL POWDER TABLETS

Publications (2)

Publication Number Publication Date
EP0829341A2 EP0829341A2 (en) 1998-03-18
EP0829341A3 true EP0829341A3 (en) 1998-04-15

Family

ID=11341588

Family Applications (1)

Application Number Title Priority Date Filing Date
EP97102534A Withdrawn EP0829341A3 (en) 1996-09-11 1997-02-17 Method and machine for producing tablets of medicinal powder

Country Status (2)

Country Link
EP (1) EP0829341A3 (en)
IT (1) IT1286212B1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9107807B2 (en) 2009-09-24 2015-08-18 Mcneil-Ppc, Inc. Machine for the manufacture of dosage forms utilizing radiofrequency energy
US9511028B2 (en) 2012-05-01 2016-12-06 Johnson & Johnson Consumer Inc. Orally disintegrating tablet

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19849434A1 (en) * 1998-10-27 2000-05-04 Isis Pharma Gmbh Divisible tablet
GB0202912D0 (en) 2002-02-07 2002-03-27 Meridica Ltd Method and apparatus for introducing powder into a pocket
RU2482839C2 (en) 2007-10-31 2013-05-27 МакНЕЙЛС-ППС, ИНК. Drug form desintegrating in oral cavity
US20110318411A1 (en) 2010-06-24 2011-12-29 Luber Joseph R Multi-layered orally disintegrating tablet and the manufacture thereof
US9445971B2 (en) 2012-05-01 2016-09-20 Johnson & Johnson Consumer Inc. Method of manufacturing solid dosage form
US9233491B2 (en) 2012-05-01 2016-01-12 Johnson & Johnson Consumer Inc. Machine for production of solid dosage forms
US9789066B2 (en) 2014-01-10 2017-10-17 Johnson & Johnson Consumer Inc. Process for making tablet using radiofrequency and lossy coated particles
US10493026B2 (en) 2017-03-20 2019-12-03 Johnson & Johnson Consumer Inc. Process for making tablet using radiofrequency and lossy coated particles
CN112121919B (en) * 2020-09-17 2022-06-03 浙江省中医药研究院 Preparation and forming device of traditional Chinese medicine preparation for treating hepatic fibrosis

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2038932A5 (en) * 1970-03-13 1971-01-08 Perry Ind Inc
DE2050885A1 (en) * 1969-10-21 1971-04-29 Fratelh Zanasi SpA, Ozzano Emilia, Bologna (Italien) Syphon dosimeter for pharmaceutical powders
US3847191A (en) * 1971-08-23 1974-11-12 T Aronson Means and methods for measuring and dispensing equal amounts of powdered material
US3893492A (en) * 1973-08-06 1975-07-08 John E Nohren Apparatus and method for accurately dispensing and consolidating powdered material into receptacles
US4542835A (en) * 1982-03-03 1985-09-24 Mg2 S.P.A. Method for filling containers with metered quantities of powdered materials
EP0561444A1 (en) * 1992-03-18 1993-09-22 AKTIENGESELLSCHAFT FüR GELD- UND KAPITALANLAGEN Machine for filling containers with cosmetic products
US5287897A (en) * 1991-01-15 1994-02-22 Mg2 S.P.A. Machine for dosing powdered pharmaceuticals
WO1996035564A1 (en) * 1995-05-09 1996-11-14 Fuisz Technologies, Ltd. Method and apparatus for forming compression dosage units
WO1996035566A1 (en) * 1995-05-09 1996-11-14 Fuisz Technologies, Ltd. Method and apparatus for forming compression dosage units within the product package
DE29619278U1 (en) * 1996-11-06 1996-12-12 Propharm Apotheker Koch GmbH, 83646 Bad Tölz Device for making tablets

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2050885A1 (en) * 1969-10-21 1971-04-29 Fratelh Zanasi SpA, Ozzano Emilia, Bologna (Italien) Syphon dosimeter for pharmaceutical powders
FR2038932A5 (en) * 1970-03-13 1971-01-08 Perry Ind Inc
US3847191A (en) * 1971-08-23 1974-11-12 T Aronson Means and methods for measuring and dispensing equal amounts of powdered material
US3893492A (en) * 1973-08-06 1975-07-08 John E Nohren Apparatus and method for accurately dispensing and consolidating powdered material into receptacles
US4542835A (en) * 1982-03-03 1985-09-24 Mg2 S.P.A. Method for filling containers with metered quantities of powdered materials
US5287897A (en) * 1991-01-15 1994-02-22 Mg2 S.P.A. Machine for dosing powdered pharmaceuticals
EP0561444A1 (en) * 1992-03-18 1993-09-22 AKTIENGESELLSCHAFT FüR GELD- UND KAPITALANLAGEN Machine for filling containers with cosmetic products
WO1996035564A1 (en) * 1995-05-09 1996-11-14 Fuisz Technologies, Ltd. Method and apparatus for forming compression dosage units
WO1996035566A1 (en) * 1995-05-09 1996-11-14 Fuisz Technologies, Ltd. Method and apparatus for forming compression dosage units within the product package
DE29619278U1 (en) * 1996-11-06 1996-12-12 Propharm Apotheker Koch GmbH, 83646 Bad Tölz Device for making tablets

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9107807B2 (en) 2009-09-24 2015-08-18 Mcneil-Ppc, Inc. Machine for the manufacture of dosage forms utilizing radiofrequency energy
US9511028B2 (en) 2012-05-01 2016-12-06 Johnson & Johnson Consumer Inc. Orally disintegrating tablet

Also Published As

Publication number Publication date
EP0829341A2 (en) 1998-03-18
ITBO960453A0 (en) 1996-09-11
ITBO960453A1 (en) 1998-03-11
IT1286212B1 (en) 1998-07-08

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