EP0799176A4 - 4,4-(disubstituted)cyclohexan-1-one dimers and related compounds - Google Patents

4,4-(disubstituted)cyclohexan-1-one dimers and related compounds

Info

Publication number
EP0799176A4
EP0799176A4 EP95943948A EP95943948A EP0799176A4 EP 0799176 A4 EP0799176 A4 EP 0799176A4 EP 95943948 A EP95943948 A EP 95943948A EP 95943948 A EP95943948 A EP 95943948A EP 0799176 A4 EP0799176 A4 EP 0799176A4
Authority
EP
European Patent Office
Prior art keywords
cyclohexan
disubstituted
dimers
related compounds
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP95943948A
Other languages
German (de)
French (fr)
Other versions
EP0799176A1 (en
Inventor
Siegfried Christensen
Joseph M Karpinski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of EP0799176A1 publication Critical patent/EP0799176A1/en
Publication of EP0799176A4 publication Critical patent/EP0799176A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
    • C07C45/59—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP95943948A 1994-12-23 1995-12-21 4,4-(disubstituted)cyclohexan-1-one dimers and related compounds Withdrawn EP0799176A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36349494A 1994-12-23 1994-12-23
US363494 1994-12-23
PCT/US1995/016719 WO1996020153A1 (en) 1994-12-23 1995-12-21 4,4-(disubstituted)cyclohexan-1-one dimers and related compounds

Publications (2)

Publication Number Publication Date
EP0799176A1 EP0799176A1 (en) 1997-10-08
EP0799176A4 true EP0799176A4 (en) 1998-03-25

Family

ID=23430462

Family Applications (1)

Application Number Title Priority Date Filing Date
EP95943948A Withdrawn EP0799176A4 (en) 1994-12-23 1995-12-21 4,4-(disubstituted)cyclohexan-1-one dimers and related compounds

Country Status (3)

Country Link
EP (1) EP0799176A4 (en)
JP (1) JPH10512552A (en)
WO (1) WO1996020153A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0799036A4 (en) * 1994-12-23 1998-03-25 Smithkline Beecham Corp 4,4-(disubstituted)cyclohexan-1-ylidine acetate dimers and related compounds

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993019748A1 (en) * 1992-04-02 1993-10-14 Smithkline Beecham Corporation Compounds useful for treating inflammatory diseases and for inhibiting production of tumor necrosis factor
WO1996019984A1 (en) * 1994-12-23 1996-07-04 Smithkline Beecham Corporation 4,4-(disubstituted)cyclohexan-1-ylidine acetate dimers and related compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4391827A (en) * 1980-09-08 1983-07-05 Pfizer Inc. 3-(2-Hydroxy-4-(substituted)phenyl)-cycloalkanone and cycloalkanol analgesic agents and intermediates therefor
GB9007762D0 (en) * 1990-04-05 1990-06-06 Beecham Group Plc Novel compounds

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993019748A1 (en) * 1992-04-02 1993-10-14 Smithkline Beecham Corporation Compounds useful for treating inflammatory diseases and for inhibiting production of tumor necrosis factor
WO1996019984A1 (en) * 1994-12-23 1996-07-04 Smithkline Beecham Corporation 4,4-(disubstituted)cyclohexan-1-ylidine acetate dimers and related compounds
WO1996019983A1 (en) * 1994-12-23 1996-07-04 Smithkline Beecham Corporation 4,4-(disubstituted)cyclohexan-1-ylidine acetate dimers and related compounds

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9620153A1 *

Also Published As

Publication number Publication date
JPH10512552A (en) 1998-12-02
EP0799176A1 (en) 1997-10-08
WO1996020153A1 (en) 1996-07-04

Similar Documents

Publication Publication Date Title
HU9302460D0 (en) 5/20/4-(1,2-benzisothiazole-3-yl)-1-pierazinyl/ethyl/-6-chlorine-1,3-dihydro-2h-indole-2-one-hydrogen-chloride-mononhydrate
EP0754041A4 (en) Novel substituted tryptamines, phenalkylamines and related compounds
EP0714293A4 (en) 3-cyano-3-(3,4-disubstituted)phenylcyclohexyl-1-carboxylates
AU3284395A (en) Synthesis of 1,1,1,3,3,-pentafluoropropane
HU9301553D0 (en) 1-(3,4-disubstituted phenyl)-tetrazolinone derivatives
EP0796096A4 (en) 4,4-(disubstituted)cyclohexan-1-carboxylate monomers and related compounds
EP0607658A3 (en) MOSFET manufacture.
EP0828493A4 (en) 4.4-(disubstituted)cyclohexan-1-ols-monomers and related compounds
EP0799176A4 (en) 4,4-(disubstituted)cyclohexan-1-one dimers and related compounds
EP0800393A4 (en) 4,4-(disubstituted)cyclohexan-1-one monomers and related compounds
PL310795A1 (en) Preparations containing difluoromethoxy-2,2,2-trifluoroethane
EP0591105A3 (en) Bisazo, bisazomethine and azo-azomethine compounds
EP0799036A4 (en) 4,4-(disubstituted)cyclohexan-1-ylidine acetate dimers and related compounds
ZA942880B (en) 2,6.disubstituted 4-quinolyl-dihydropridines
ZA933848B (en) Pyridyl-1,2,5-oxadiazolecarboxamide-2-oxides
EP0799187A4 (en) 4,4-(disubstituted)cyclohexan-1-carboxylate dimers and related compounds
EP0799184A4 (en) 4,4-(disubstituted)cyclohexan-1-ol dimers and related compounds
EP0796092A4 (en) 3,3-(disubstituted)cyclohexan-1-one dimers and related compounds
EP0799181A4 (en) 3,3-(disubstituted)cyclohexan-1-carboxylate dimers and related compounds
ZA9510826B (en) 3,3-(disubstituted)cyclohexan-1-ol monomers and related compounds
ZA9510884B (en) 4,4-(disubstituted) cyclohexan-1-one monomers and related compounds
EP0799185A4 (en) 1,3,3-(trisubstituted)cyclohexane dimers and related compounds
ZA9510829B (en) 3,3-(disubstituted)cyclohexan-1-one monomers and related compounds
EP0799186A4 (en) 1,4,4-(trisubstituted)cyclohex-1-ene dimers and related compounds
IL116490A0 (en) 4,4-(disubstituted) cyclohexan-1-ol monomers and related compounds

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19970721

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): BE CH DE DK FR GB IT LI NL

RHK1 Main classification (correction)

Ipc: A61K 31/12

A4 Supplementary search report drawn up and despatched

Effective date: 19980206

AK Designated contracting states

Kind code of ref document: A4

Designated state(s): BE CH DE DK FR GB IT LI NL

17Q First examination report despatched

Effective date: 19980703

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19981114