EP0650596A4 - Compositions and methods for regulating cellular signal transducing systems. - Google Patents

Compositions and methods for regulating cellular signal transducing systems.

Info

Publication number
EP0650596A4
EP0650596A4 EP92917394A EP92917394A EP0650596A4 EP 0650596 A4 EP0650596 A4 EP 0650596A4 EP 92917394 A EP92917394 A EP 92917394A EP 92917394 A EP92917394 A EP 92917394A EP 0650596 A4 EP0650596 A4 EP 0650596A4
Authority
EP
European Patent Office
Prior art keywords
compositions
methods
cellular signal
signal transducing
regulating cellular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP92917394A
Other languages
German (de)
French (fr)
Other versions
EP0650596A1 (en
Inventor
Geoffrey J Schmidt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Schepens Eye Research Institute Inc
Original Assignee
Schepens Eye Research Institute Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schepens Eye Research Institute Inc filed Critical Schepens Eye Research Institute Inc
Publication of EP0650596A1 publication Critical patent/EP0650596A1/en
Publication of EP0650596A4 publication Critical patent/EP0650596A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4722—G-proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Oncology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Toxicology (AREA)
EP92917394A 1992-03-27 1992-03-30 Compositions and methods for regulating cellular signal transducing systems. Withdrawn EP0650596A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85884192A 1992-03-27 1992-03-27
US858841 1992-03-27
PCT/US1992/002632 WO1993020439A1 (en) 1992-03-27 1992-03-30 Compositions and methods for regulating cellular signal transducing systems

Publications (2)

Publication Number Publication Date
EP0650596A1 EP0650596A1 (en) 1995-05-03
EP0650596A4 true EP0650596A4 (en) 1996-01-24

Family

ID=25329337

Family Applications (1)

Application Number Title Priority Date Filing Date
EP92917394A Withdrawn EP0650596A4 (en) 1992-03-27 1992-03-30 Compositions and methods for regulating cellular signal transducing systems.

Country Status (5)

Country Link
EP (1) EP0650596A4 (en)
JP (1) JPH07507537A (en)
AU (1) AU1873592A (en)
CA (1) CA2132624A1 (en)
WO (1) WO1993020439A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE208041T1 (en) * 1995-01-10 2001-11-15 Schepens Eye Res Inst A-PROTEIN AS A DIAGNOSTIC FOR CANCER
US5840569A (en) * 1996-12-12 1998-11-24 Incyte Pharmaceuticals, Inc. Human GTP-binding proteins
CN113980306B (en) * 2021-09-29 2023-12-19 浙江工商大学 Edible cyclic adenosine monophosphate-agar polysaccharide packaging film and preparation method thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4820631A (en) * 1986-07-30 1989-04-11 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Deletion mutants and monoclonal antibodies against ras proteins
US4870161A (en) * 1987-09-25 1989-09-26 The United States Of America As Represented By The Department Of Health And Human Services Reagents and probes for distinguishing and isolating different GTP-binding proteins

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
SCHMIDT ET AL: "ACTIVATION OF MEMBRANE-BOUND AND SOLUBLE A-PROTEIN IN THE BOVINE ROD OUTER SEGMENT", INVEST.OPHTHALMOL.VISUAL SCI., vol. 30, no. S3, pages 172 *
SCHMIDT ET AL: "A-PROTEIN CATALYSES THE ADP-RIBOSYLATION OF G-PROTEIN FROM COW ROD OUTER SEGMENTS", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 262, no. 29, 15 October 1987 (1987-10-15), pages 14333 - 14336 *
SCHMIDT ET AL: "A-PROTEIN:COFACTOR FOR CHOLERA TOXIN-DEPENDENT ADP-RIBOSYLATION OF G-PROTEIN IN BOVINE ROS", INVEST.OPHTHALMOL.VISUAL SCI., vol. 27, no. S3, pages 216 *
SCHMIDT ET AL: "INHIBITION OF PIP2 HYDROLYSIS BY MONOCLONAL ANTIBODIES RAISED AGAINST BOVINE ROS A-PROTEIN", INVEST.OPHTHALMOL.VISUAL SCI., vol. 31, no. 4 ABS.ISSUE, pages 581 *
See also references of WO9320439A1 *

Also Published As

Publication number Publication date
EP0650596A1 (en) 1995-05-03
WO1993020439A1 (en) 1993-10-14
AU1873592A (en) 1993-11-08
CA2132624A1 (en) 1993-10-14
JPH07507537A (en) 1995-08-24

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