EP0644756A4 - System for controlled release of antiarrhythmic agents. - Google Patents

System for controlled release of antiarrhythmic agents.

Info

Publication number
EP0644756A4
EP0644756A4 EP94912237A EP94912237A EP0644756A4 EP 0644756 A4 EP0644756 A4 EP 0644756A4 EP 94912237 A EP94912237 A EP 94912237A EP 94912237 A EP94912237 A EP 94912237A EP 0644756 A4 EP0644756 A4 EP 0644756A4
Authority
EP
European Patent Office
Prior art keywords
controlled release
antiarrhythmic agents
antiarrhythmic
agents
release
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP94912237A
Other languages
German (de)
French (fr)
Other versions
EP0644756A1 (en
Inventor
Robert J Levy
Amnon Sintov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Michigan
Original Assignee
University of Michigan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Michigan filed Critical University of Michigan
Publication of EP0644756A1 publication Critical patent/EP0644756A1/en
Publication of EP0644756A4 publication Critical patent/EP0644756A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/3629—Heart stimulators in combination with non-electric therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/38—Applying electric currents by contact electrodes alternating or intermittent currents for producing shock effects
    • A61N1/39—Heart defibrillators
    • A61N1/3956—Implantable devices for applying electric shocks to the heart, e.g. for cardioversion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EP94912237A 1993-03-15 1994-03-15 System for controlled release of antiarrhythmic agents. Withdrawn EP0644756A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33307 1987-04-02
US3330793A 1993-03-15 1993-03-15
PCT/US1994/002838 WO1994021237A1 (en) 1993-03-15 1994-03-15 System for controlled release of antiarrhythmic agents

Publications (2)

Publication Number Publication Date
EP0644756A1 EP0644756A1 (en) 1995-03-29
EP0644756A4 true EP0644756A4 (en) 1996-02-28

Family

ID=21869658

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94912237A Withdrawn EP0644756A4 (en) 1993-03-15 1994-03-15 System for controlled release of antiarrhythmic agents.

Country Status (7)

Country Link
EP (1) EP0644756A4 (en)
JP (1) JPH07509735A (en)
KR (1) KR950702101A (en)
AU (1) AU6446794A (en)
CA (1) CA2135767A1 (en)
NZ (1) NZ263685A (en)
WO (1) WO1994021237A1 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6322548B1 (en) 1995-05-10 2001-11-27 Eclipse Surgical Technologies Delivery catheter system for heart chamber
US6524298B1 (en) 1995-06-07 2003-02-25 Cardiogenesis Corporation Therapeutic and diagnostic agent delivery
US6775574B1 (en) * 1997-11-07 2004-08-10 Medtronic, Inc. Method and system for myocardial infarction repair
US7031775B2 (en) 1997-11-07 2006-04-18 Medtronic, Inc. Method and system for myocardial infarction repair
ES2169980B1 (en) 1999-12-17 2003-11-01 Lipotec Sa MICROCAPSULES FOR THE PROLONGED RELEASE OF PHARMACOS.
US6613025B1 (en) 2000-05-25 2003-09-02 Scimed Life Systems, Inc. Method and apparatus for diagnostic and therapeutic agent delivery
US6572534B1 (en) 2000-09-14 2003-06-03 Abiomed, Inc. System and method for implanting a cardiac wrap
US6846296B1 (en) 2000-09-14 2005-01-25 Abiomed, Inc. Apparatus and method for detachably securing a device to a natural heart
US6540659B1 (en) 2000-11-28 2003-04-01 Abiomed, Inc. Cardiac assistance systems having bi-directional pumping elements
US6616596B1 (en) 2000-11-28 2003-09-09 Abiomed, Inc. Cardiac assistance systems having multiple layers of inflatable elements
US6602182B1 (en) 2000-11-28 2003-08-05 Abiomed, Inc. Cardiac assistance systems having multiple fluid plenums
US6547716B1 (en) 2000-11-28 2003-04-15 Abiomed, Inc. Passive cardiac restraint systems having multiple layers of inflatable elements
JP2004518664A (en) 2000-12-27 2004-06-24 ジェンザイム・コーポレーション Controlled release of antiarrhythmic drugs
US20030009145A1 (en) * 2001-03-23 2003-01-09 Struijker-Boudier Harry A.J. Delivery of drugs from sustained release devices implanted in myocardial tissue or in the pericardial space
US20020188327A1 (en) * 2001-04-26 2002-12-12 Chester Struble Drug delivery for treatment of cardiac arrhythmia
US6626821B1 (en) 2001-05-22 2003-09-30 Abiomed, Inc. Flow-balanced cardiac wrap
EP1451306A1 (en) * 2001-11-06 2004-09-01 Medtronic, Inc. Method and system for myocardial infarction repair
US6968226B2 (en) 2002-01-30 2005-11-22 Medtronic, Inc. Method and system for terminating an atrial arrhythmia
AU2003248751A1 (en) * 2002-06-28 2004-01-19 Genzyme Corporation Controlled release of anti-arrhythmic agents
US7917208B2 (en) 2002-10-04 2011-03-29 Microchips, Inc. Medical device for controlled drug delivery and cardiac monitoring and/or stimulation
KR20080073328A (en) * 2005-11-16 2008-08-08 토카이 유니버시티 에듀케이셔널시스템 Controlled drug release composition and drug releasing medical device

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992017240A1 (en) * 1991-04-05 1992-10-15 Medtronic, Inc. Subcutaneous multi-electrode sensing system

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4374669A (en) * 1975-05-09 1983-02-22 Mac Gregor David C Cardiovascular prosthetic devices and implants with porous systems
US4506680A (en) * 1983-03-17 1985-03-26 Medtronic, Inc. Drug dispensing body implantable lead
US5090422A (en) * 1990-04-19 1992-02-25 Cardiac Pacemakers, Inc. Implantable electrode pouch
US5087243A (en) * 1990-06-18 1992-02-11 Boaz Avitall Myocardial iontophoresis
US5154182A (en) * 1991-02-15 1992-10-13 Siemens Pacesetter, Inc. Drug or steroid releasing patch electrode for an implantable arrhythmia treatment system

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992017240A1 (en) * 1991-04-05 1992-10-15 Medtronic, Inc. Subcutaneous multi-electrode sensing system

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9421237A1 *

Also Published As

Publication number Publication date
WO1994021237A1 (en) 1994-09-29
KR950702101A (en) 1995-06-19
EP0644756A1 (en) 1995-03-29
NZ263685A (en) 1997-08-22
AU6446794A (en) 1994-10-11
JPH07509735A (en) 1995-10-26
CA2135767A1 (en) 1994-09-29

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