EP0517812A4 - Angiotensin ii antagonists incorporating a substituted benzyl element - Google Patents
Angiotensin ii antagonists incorporating a substituted benzyl elementInfo
- Publication number
- EP0517812A4 EP0517812A4 EP91905733A EP91905733A EP0517812A4 EP 0517812 A4 EP0517812 A4 EP 0517812A4 EP 91905733 A EP91905733 A EP 91905733A EP 91905733 A EP91905733 A EP 91905733A EP 0517812 A4 EP0517812 A4 EP 0517812A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- angiotensin
- substituted benzyl
- antagonists incorporating
- benzyl element
- antagonists
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/08—Radicals containing only hydrogen and carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
- C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
- C07D239/91—Oxygen atoms with aryl or aralkyl radicals attached in position 2 or 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/12—Oxygen or sulfur atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US47978690A | 1990-02-13 | 1990-02-13 | |
US479786 | 1990-02-13 |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0517812A1 EP0517812A1 (en) | 1992-12-16 |
EP0517812A4 true EP0517812A4 (en) | 1995-10-18 |
Family
ID=23905431
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP91905007A Withdrawn EP0515535A4 (en) | 1990-02-13 | 1991-02-11 | Angiotensin ii antagonists incorporating a substituted benzyl element |
EP91905733A Withdrawn EP0517812A4 (en) | 1990-02-13 | 1991-02-11 | Angiotensin ii antagonists incorporating a substituted benzyl element |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP91905007A Withdrawn EP0515535A4 (en) | 1990-02-13 | 1991-02-11 | Angiotensin ii antagonists incorporating a substituted benzyl element |
Country Status (4)
Country | Link |
---|---|
EP (2) | EP0515535A4 (en) |
JP (2) | JPH05503530A (en) |
CA (2) | CA2075637A1 (en) |
WO (2) | WO1991011999A1 (en) |
Families Citing this family (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5449682A (en) * | 1990-02-13 | 1995-09-12 | Merck & Co., Inc. | Angiotensin II antagonists incorporating a substituted benzyl element |
US5240938A (en) * | 1991-02-13 | 1993-08-31 | Merck & Co., Inc. | Angiotensin II antagonists incorporating a substituted pyridoimidazolyl ring |
US5177095A (en) * | 1990-02-13 | 1993-01-05 | Merck & Co., Inc. | Triazole angiotensin II antagonists incorporating a substituted benzyl element |
US5183810A (en) * | 1990-02-13 | 1993-02-02 | Merck & Co., Inc. | Imidazole angiotensin II antagonists incorporating a substituted benzyl element |
US5246944A (en) * | 1991-08-13 | 1993-09-21 | Merck & Co., Inc. | Quinoline angiotensin ii antagonists incorporating a substituted benzyl element |
SG42942A1 (en) * | 1991-09-10 | 1997-10-17 | Tanabe Seiyaku Co | Imidazopyridine derivatives and process for preparation thereof |
US5187159A (en) * | 1991-10-07 | 1993-02-16 | Merck & Co., Inc. | Angiotensin II antagonists incorporating a substituted 1,3-benzodioxole or 1,3-benzodithiole |
GB9121727D0 (en) * | 1991-10-14 | 1991-11-27 | Ici Plc | Heterocyclic compounds |
TW226375B (en) * | 1991-10-24 | 1994-07-11 | American Home Prod | |
US5442062A (en) * | 1991-10-24 | 1995-08-15 | The Upjohn Company | Imidazole derivatives and pharmaceutical compositions containing the same |
WO1994000450A1 (en) * | 1992-06-25 | 1994-01-06 | Zeneca Limited | Chromanderivatives as angiotensin ii antagonists |
GB9218449D0 (en) | 1992-08-29 | 1992-10-14 | Boots Co Plc | Therapeutic agents |
CA2139930A1 (en) * | 1992-07-10 | 1994-01-20 | Alan Martin Birch | Dioxycyclobutene derivatives as angiotensin ii antagonists |
DE4302956A1 (en) * | 1993-02-03 | 1994-08-04 | Bayer Ag | Substituted imidazo (4,5-b) pyridines and benzimidazoles |
US5300668A (en) * | 1993-03-10 | 1994-04-05 | Pfizer Inc. | Certain esters of 1-(4-X-methylphenyl)cyclopent-3-ene-1-carboxylic acid, wherein X is a trialkylsilyloxy, bromo or hydroxy group, as intermediates |
US5420133A (en) * | 1993-03-19 | 1995-05-30 | Merck & Co., Inc. | Quinazolinones substituted with phenoxyphenylacetic acid derivatives |
US5401745A (en) * | 1993-03-19 | 1995-03-28 | Merck & Co., Inc. | Quinazolinones substituted with phenoxyphenylacetic acid derivatives |
US5334598A (en) * | 1993-03-19 | 1994-08-02 | Merck & Co., Inc. | Six-membered ring fused imidazoles substituted with phenoxyphenylacetic acid derivatives |
US5491172A (en) * | 1993-05-14 | 1996-02-13 | Warner-Lambert Company | N-acyl sulfamic acid esters (or thioesters), N-acyl sulfonamides, and N-sulfonyl carbamic acid esters (or thioesters) as hypercholesterolemic agents |
IL109431A (en) * | 1993-05-14 | 2001-01-11 | Warner Lambert Co | Pharmaceutical compositions containing n-acyl sulfamic acid esters (or thioesters), n-acyl sulfonamides, and n-sulfonyl carbamic acid esters (or thioesters), for regulating plasma cholesterol concentration, and certain such novel compounds |
AP9400651A0 (en) * | 1993-07-15 | 1995-12-30 | Pfizer | Azacyclic-heterocyclic compounds as angiotensin II receptor antagonists. |
DE4327256A1 (en) * | 1993-08-13 | 1995-02-16 | Bayer Ag | Sulfonylbenzyl-substituted benzimidazoles, process for their preparation and their use in medicaments |
ES2079315B1 (en) * | 1994-02-24 | 1996-10-16 | Uriach & Cia Sa J | NEW IMIDAZOPIRIDINES. |
US5798344A (en) * | 1994-03-08 | 1998-08-25 | Otsuka Pharmaceutical Factory, Inc. | Phosphonic ester derivatives of quinazolinones |
ES2152396T3 (en) * | 1994-04-06 | 2001-02-01 | Shionogi & Co | DERIVED FROM PHENYLACETIC ACID WITH REPLACEMENT IN GAMMA, ITS PROCEDURE FOR OBTAINING AND AGRICULTURAL BACTERICIDE CONTAINING IT. |
ATE216261T1 (en) * | 1995-06-07 | 2002-05-15 | Searle & Co | COMBINATION THERAPY FOR THE TREATMENT OF CONGESTIVE HEART FAILURE WITH SPIRONOLACTONE AND ANGIOTENSIN II ANTAGONIST |
WO1996040255A2 (en) * | 1995-06-07 | 1996-12-19 | G.D. Searle & Co. | Method to treat cardiofibrosis with a combination therapy of an angiotensin ii antagonist and an epoxy-steroidal aldosterone antagonist |
GB9716446D0 (en) * | 1997-08-05 | 1997-10-08 | Agrevo Uk Ltd | Fungicides |
CA2336714A1 (en) | 1998-07-06 | 2000-01-13 | Bristol-Myers Squibb Company | Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists |
US6174912B1 (en) | 1998-08-21 | 2001-01-16 | Dupont Pharmaceuticals Company | Nitrogen substituted imidazo[4,5-C]pyrazoles as corticotropin releasing hormone antagonists |
SE9903028D0 (en) | 1999-08-27 | 1999-08-27 | Astra Ab | New use |
GB0328295D0 (en) * | 2003-12-05 | 2004-01-07 | Muscagen Ltd | Therapeutic compounds |
AU2005231123A1 (en) * | 2004-03-08 | 2005-10-20 | Wyeth | Ion channel modulators |
ME02005B (en) | 2005-09-14 | 2012-08-31 | Takeda Pharmaceuticals Co | Dipeptidyl peptidase inhibitors for treating diabetes |
CA2622642C (en) | 2005-09-16 | 2013-12-31 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
TW200838536A (en) | 2006-11-29 | 2008-10-01 | Takeda Pharmaceutical | Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor |
AU2008261102B2 (en) | 2007-06-04 | 2013-11-28 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
JP2011520969A (en) * | 2008-05-19 | 2011-07-21 | シェーリング コーポレイション | Bicyclic heterocyclic derivatives and their use as GPR119 modulators |
CA2930674A1 (en) | 2008-06-04 | 2009-12-10 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
JP2011528375A (en) | 2008-07-16 | 2011-11-17 | シナジー ファーマシューティカルズ インコーポレイテッド | Guanylate cyclase agonists useful for the treatment of gastrointestinal disorders, inflammation, cancer, and other disorders |
WO2010137336A1 (en) | 2009-05-29 | 2010-12-02 | 興和株式会社 | NOVEL α-PHENOXYBENZENEACETIC ACID DERIVATIVE AND PHARMACEUTICAL PREPARATION COMPRISING SAME |
WO2011138657A1 (en) * | 2010-05-04 | 2011-11-10 | Glenmark Pharmaceuticals S.A. | Aryl substituted olefinic compounds as pde10a inhibitors |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
CA2905438A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
JP2016514670A (en) | 2013-03-15 | 2016-05-23 | シナジー ファーマシューティカルズ インコーポレイテッド | Guanylate cyclase receptor agonists in combination with other drugs |
JP6606491B2 (en) | 2013-06-05 | 2019-11-13 | シナジー ファーマシューティカルズ インコーポレイテッド | Ultra high purity agonist of guanylate cyclase C, method for producing and using the same |
TWI731317B (en) * | 2013-12-10 | 2021-06-21 | 美商健臻公司 | Tropomyosin-related kinase (trk) inhibitors |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990009997A1 (en) * | 1989-02-23 | 1990-09-07 | British Bio-Technology Limited | Novel benzimidazole derivatives |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3962244A (en) * | 1971-01-23 | 1976-06-08 | Hoechst Aktiengesellschaft | Benzene sulfonyl ureas |
US4420487A (en) * | 1978-04-10 | 1983-12-13 | The Purdue Frederick Company | Diuretic and antihypertensive benzimidazoles |
NZ192392A (en) * | 1978-12-19 | 1983-02-15 | M Ishikawa | 3-(substituted (phenyl or pyridyl)) -3,4-dihydroquinazolin-4-ones |
US4728741A (en) * | 1985-01-08 | 1988-03-01 | Smithkline Beckman Corporation | 1-substituted-2-mercapto benzimidazole compounds and intermediates |
US4772600A (en) * | 1986-06-09 | 1988-09-20 | A. H. Robins Company, Inc. | Fused imidazoheterocyclic compounds and pharmaceutical compositions |
EP0260621A3 (en) * | 1986-09-18 | 1989-03-15 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | 3-aryl uracil-enol ethers and their use as herbicides |
JPH07107056B2 (en) * | 1987-01-30 | 1995-11-15 | 日清製粉株式会社 | 4 (3H) -quinazolinone derivative, method for producing the same and antiulcer agent containing the same |
AU2328188A (en) * | 1987-09-23 | 1989-04-18 | Ciba-Geigy Ag | Heterocyclic compounds |
-
1991
- 1991-02-11 EP EP91905007A patent/EP0515535A4/en not_active Withdrawn
- 1991-02-11 JP JP3504721A patent/JPH05503530A/en active Pending
- 1991-02-11 CA CA002075637A patent/CA2075637A1/en not_active Abandoned
- 1991-02-11 EP EP91905733A patent/EP0517812A4/en not_active Withdrawn
- 1991-02-11 WO PCT/US1991/000957 patent/WO1991011999A1/en not_active Application Discontinuation
- 1991-02-11 CA CA002075627A patent/CA2075627A1/en not_active Abandoned
- 1991-02-11 WO PCT/US1991/000993 patent/WO1991012001A1/en not_active Application Discontinuation
- 1991-02-11 JP JP3505964A patent/JPH05504969A/en active Pending
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990009997A1 (en) * | 1989-02-23 | 1990-09-07 | British Bio-Technology Limited | Novel benzimidazole derivatives |
Non-Patent Citations (1)
Title |
---|
See also references of WO9111999A1 * |
Also Published As
Publication number | Publication date |
---|---|
WO1991011999A1 (en) | 1991-08-22 |
EP0517812A1 (en) | 1992-12-16 |
CA2075627A1 (en) | 1991-08-14 |
CA2075637A1 (en) | 1991-08-14 |
EP0515535A4 (en) | 1996-01-17 |
JPH05503530A (en) | 1993-06-10 |
JPH05504969A (en) | 1993-07-29 |
EP0515535A1 (en) | 1992-12-02 |
WO1991012001A1 (en) | 1991-08-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP0515535A4 (en) | Angiotensin ii antagonists incorporating a substituted benzyl element | |
EP0515546A4 (en) | Triazole angiotensin ii antagonists incorporating a substituted benzyl element | |
EP0475206A3 (en) | Angiotensin ii receptor antagonists | |
IL105877A0 (en) | Angiotensin ii antagonists | |
EP0543491A3 (en) | Angiotensin ii antagonists having a substituted 1,3-benzodioxolering or 1,3-benzodithiolering | |
EP0586613A4 (en) | Bradykinin antagonists | |
HU913074D0 (en) | Fibrinogenic receptor antagonists | |
AU3276293A (en) | Angiotensin II receptor antagonists | |
GB2272376B (en) | A multifunction multielectrode device | |
ZA916711B (en) | Bradykinin antagonists | |
HU9503067D0 (en) | Endotheline receptor antagonists | |
GB9317760D0 (en) | Angiotensin ii antagonist | |
EP0515548A4 (en) | Imidazole angiotensin ii antagonists incorporating a substituted benzyl element | |
EP0505111A3 (en) | Angiotensin ii antagonists incorporating a substituted imidazo (1,2-b)(1,2,4) triazole | |
GB9317758D0 (en) | Angiotensin ii antagonist | |
DE69204920T2 (en) | Angiotensin II antagonists. | |
EP0546449A3 (en) | Benzofuranderivatives as angiotensin ii antagonists | |
GB9303632D0 (en) | Quinoline and azaquinoline angiotensin ii antagonists incorporating a substituted biphenyl element | |
GB9216958D0 (en) | Angiotensin ii antagonists incorporating a substituted benzyl element | |
GB9217033D0 (en) | Angiotensin ii antagonists incorporating a substituted benzyl element | |
ZA931146B (en) | A novel 5-ht3-receptor antagonist. | |
GB9217034D0 (en) | Triazole angiotensin ii antagonists incorporating a substituted benzyl element | |
ZA917693B (en) | Fibrinogen receptor antagonists | |
GB9216995D0 (en) | Imidazole angiotensin ii antagonists incorporating a substituted benzyl element bearing a heterocyclyl | |
IL120336A0 (en) | Angiotensin II antagonists |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19920808 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): CH DE FR GB IT LI NL |
|
RHK1 | Main classification (correction) |
Ipc: C07D471/04 |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 19950904 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): CH DE FR GB IT LI NL |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 19980901 |