EP0344211A4 - Monoclonal antibodies in vaccine formulations. - Google Patents

Monoclonal antibodies in vaccine formulations.

Info

Publication number
EP0344211A4
EP0344211A4 EP19880902682 EP88902682A EP0344211A4 EP 0344211 A4 EP0344211 A4 EP 0344211A4 EP 19880902682 EP19880902682 EP 19880902682 EP 88902682 A EP88902682 A EP 88902682A EP 0344211 A4 EP0344211 A4 EP 0344211A4
Authority
EP
European Patent Office
Prior art keywords
monoclonal antibodies
vaccine formulations
vaccine
formulations
monoclonal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP19880902682
Other languages
German (de)
French (fr)
Other versions
EP0344211A1 (en
Inventor
Giuseppe Colucci
Samuel D Waksal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ImClone LLC
Original Assignee
ImClone Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ImClone Systems Inc filed Critical ImClone Systems Inc
Publication of EP0344211A1 publication Critical patent/EP0344211A1/en
Publication of EP0344211A4 publication Critical patent/EP0344211A4/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C07K16/082—Hepadnaviridae, e.g. hepatitis B virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4216—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-viral Ig
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4233—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-bacterial Ig
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
EP19880902682 1987-02-20 1988-02-19 Monoclonal antibodies in vaccine formulations. Ceased EP0344211A4 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US1680787A 1987-02-20 1987-02-20
US16807 1987-02-20
US15669188A 1988-02-17 1988-02-17
US156691 1988-02-17

Publications (2)

Publication Number Publication Date
EP0344211A1 EP0344211A1 (en) 1989-12-06
EP0344211A4 true EP0344211A4 (en) 1990-03-12

Family

ID=21779094

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19880902682 Ceased EP0344211A4 (en) 1987-02-20 1988-02-19 Monoclonal antibodies in vaccine formulations.

Country Status (4)

Country Link
EP (1) EP0344211A4 (en)
JP (1) JPH02502183A (en)
AU (2) AU1484688A (en)
WO (1) WO1988006040A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5955076A (en) * 1989-06-15 1999-09-21 Peptide Therapeutics Limited Immunoactive peptides and antibodies and their use in anti-allergy treatment
GB8913737D0 (en) * 1989-06-15 1989-08-02 Univ Birmingham A novel anti-allergy treatment
KR100498198B1 (en) 1996-03-01 2005-09-09 노파르티스 아게 Peptide Immunogen for Vaccination against and Treatment of Allergy

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0142345A2 (en) * 1983-11-09 1985-05-22 Synbiotics Corporation Anti-idiotypic vaccine employing anti-idiotypic monoclonal antibodies
WO1986001539A1 (en) * 1984-08-27 1986-03-13 The Trustees Of Columbia University In The City Of Method of producing monoclonal anti-idiotypic antibodies
WO1988001304A1 (en) * 1986-08-21 1988-02-25 The Trustees Of Columbia University In The City Of Dna encoding the t cell surface protein t4 and use of fragments of t4 in the treatment of aids

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4596792A (en) * 1981-09-04 1986-06-24 The Regents Of The University Of California Safe vaccine for hepatitis containing polymerized serum albumin
US4661586A (en) * 1981-11-17 1987-04-28 The Board Of Trustees Of The Leland Stanford Junior University Monoclonal anti-idiotype antibodies
JPS59116230A (en) * 1982-11-29 1984-07-05 ベイロ−・カレツジ・オヴ・メデイスン Anti-ideio type antibody producing immunological response against viral infectious factor
EP0141783B2 (en) * 1983-11-07 1993-06-16 The Wistar Institute Immune response to tumours and viruses induced by anti-idiotype antibodies
CA1256795A (en) * 1983-12-28 1989-07-04 Dennis A. Carson Anti-idiotype antibodies induced by synthetic polypeptides
US4683295A (en) * 1984-05-24 1987-07-28 Scripps Clinic And Research Foundation Method for the preparation of anti-receptor antibodies

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0142345A2 (en) * 1983-11-09 1985-05-22 Synbiotics Corporation Anti-idiotypic vaccine employing anti-idiotypic monoclonal antibodies
WO1986001539A1 (en) * 1984-08-27 1986-03-13 The Trustees Of Columbia University In The City Of Method of producing monoclonal anti-idiotypic antibodies
WO1988001304A1 (en) * 1986-08-21 1988-02-25 The Trustees Of Columbia University In The City Of Dna encoding the t cell surface protein t4 and use of fragments of t4 in the treatment of aids

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
EUROPEAN JOURNAL OF IMMUNOLOGY, vol. 17, 1987, pages 365-370, Verlagsgesellschaft mbH, Weinheim, DE; G. COLUCCI et al.: "Interactions between hepatitis B virus and polymeric human albumin. I Production of monoclonal anti-idiotypes (anti-anti-polymeric human albumin) which recognize hepatitis B virus surface antigen" *
EUROPEAN JOURNAL OF IMMUNOLOGY, vol. 17, 1987, pages 371-374, Verlagsgesellschaft mbH, Weinheim, DE; G. COLUCCI et al.: "Interactions between hepatitis B virus and polymeric human serum albumin II. Development of syngeneic monoclonal anti-anti-idiotypes which mimic hepatitis B surface antigen in the induction of immune responsiveness" *
See also references of WO8806040A1 *
THE JOURNAL OF IMMUNOLOGY, vol. 137, no. 9, 1st November 1986, pages 2937-2944, The American Association of Immunologists, US; J.S. McDOUGAL et al.: "Binding of the human retrovirus HTLV-III/LAV/ARV/HIV to the CD4 (T4) molecule: conformation dependence, epitope mapping, antibody, inhibition, and potential for idiotypic mimicry" *

Also Published As

Publication number Publication date
AU5217890A (en) 1990-09-06
JPH02502183A (en) 1990-07-19
WO1988006040A1 (en) 1988-08-25
AU1484688A (en) 1988-09-14
EP0344211A1 (en) 1989-12-06

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19890817

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE FR GB IT LI LU NL SE

RIN1 Information on inventor provided before grant (corrected)

Inventor name: COLUCCI, GIUSEPPE

Inventor name: WAKSAL, SAMUEL, D.

A4 Supplementary search report drawn up and despatched

Effective date: 19900312

17Q First examination report despatched

Effective date: 19911219

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED

18R Application refused

Effective date: 19930501