EP0318924A1 - Thawing and warming-up device for medical products - Google Patents

Thawing and warming-up device for medical products Download PDF

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Publication number
EP0318924A1
EP0318924A1 EP88119889A EP88119889A EP0318924A1 EP 0318924 A1 EP0318924 A1 EP 0318924A1 EP 88119889 A EP88119889 A EP 88119889A EP 88119889 A EP88119889 A EP 88119889A EP 0318924 A1 EP0318924 A1 EP 0318924A1
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EP
European Patent Office
Prior art keywords
plastic bags
thawing
temperature control
plastic
pressure member
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Granted
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EP88119889A
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German (de)
French (fr)
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EP0318924B1 (en
Inventor
Volker Barkey
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/44—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for cooling or heating the devices or media
    • A61M5/445—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for cooling or heating the devices or media the media being heated in the reservoir, e.g. warming bloodbags
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0281—Apparatus for treatment of blood or blood constituents prior to transfusion, e.g. washing, filtering or thawing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/025—Means for agitating or shaking blood containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/36—General characteristics of the apparatus related to heating or cooling
    • A61M2205/366—General characteristics of the apparatus related to heating or cooling by liquid heat exchangers

Definitions

  • the invention relates to a thawing and tempering device for medical products, in particular for frozen plasma or blood preserves, with at least two plastic bags containing a tempered medium and to be arranged on both sides of a product to be tempered.
  • Such a device is known from DE-GM 86 06 622 of the applicant.
  • Numerous medical products, especially plasma solutions or blood preserves are stored in freezers or freezers at minus 20 ° C and, if necessary, have to be quickly transferred to e.g. 37 ° C to be heated. Local overheating of the preserve should be avoided, since it can lead to coagulation in the case of blood preserves or undesirable chemical reactions in other preserves.
  • the invention has for its object to provide a device that makes it possible to further increase the temperature control compared to the known device without the risk of overheating and damage to the product.
  • the temperature control medium in the plastic bag is caused to vibrate by the pressure member, so that a rocking movement occurs, which is communicated to the medical product, for example a plasma bag.
  • This also causes the product to move so that the temperature equalization is accelerated from the outside in and across the entire product. A smooth and rapid movement without local overheating is therefore achieved.
  • it is even possible to increase the temperature of the temperature control medium within certain limits compared to the desired end temperature of the product and thus achieve further acceleration, since local overheating on the outer surface of the product can be avoided through the rocking movement and the rapid temperature compensation.
  • the device has two superimposed, essentially congruent, plastic bags filled with the temperature-controlled medium, between which the product to be temperature-controlled is placed after the upper bag has been lifted off, and the pressure element consists of a rotating eccentric that enters between the plastic bags and which alternates acts on the plastic bag.
  • the internal pressure or degree of filling of the plastic bags is preferably reduced during a rocking operation. In this way, the temperature-controlled medium can be set into vibration more easily than is the case with a bulging bag.
  • the pressure member acts on an edge region of the plastic bag or bags.
  • This not only has the advantage that the central area of the plastic bag is available as a contact surface for the medical product, but the desired vibrations can also be achieved more reliably from an edge of the plastic bag.
  • the plastic bags can have a reinforcement that reduces wear and can also be flat, so that it distributes the pressure of the pressure member over a larger area of the plastic bags.
  • Fig. 1 shows a device according to the invention with a box-shaped housing 10, on the top of which a hinged lid 12 is provided.
  • the inside of the housing is through a horizontal plate 14 in an upper Temperature control chamber 16 and a lower hot water chamber 18 divided.
  • the plastic bags consist for example of a soft, temperature-resistant material such as e.g. PVC. Both plastic bags have hose connections 24, 26, 28, 30, which form the inlet and outlet of the two plastic bags 20, 22 in pairs.
  • the hose connections 24, 26, 28, 30 are connected in a manner not shown to a pump 32, which circulates hot water from the hot water chamber 18 through the plastic bag parts 20, 22.
  • the hose connections of the plastic bags are connected in opposite directions, so that for example the hose connections 24, 26, which are shown on the left in FIG. 1, form the inlet for the lower plastic bag and the outlet for the upper plastic bag. This compensates for the effect of a temperature drop occurring in the plastic bags.
  • heating coils 34 are provided which, in conjunction with control electronics 36 arranged on the end face of the housing 10, enable a completely uniform and precise temperature setting of the temperature control medium.
  • the upper plastic bag 22 is lifted up, the plasma bags are placed on the lower plastic bag 20, and the upper plastic bag 22 is again placed on the plasma bags. Due to the soft material of the plastic bags, they close closely to the plasma bag so that rapid heat transfer can take place.
  • the temperature control chamber 16, together with the plate 14, is preferably designed as a watertight collecting trough, in which traces of liquid can be quickly noticed, so that the cause thereof can be eliminated.
  • the upper plastic bag 22 can be suspended from the lid 12 so that it is automatically raised when the lid is opened.
  • a shaft 42 emerges between the hose connections 24, 26 and 28, 30 and is connected to a drive motor (not shown) outside the temperature control chamber 16.
  • the shaft 42 extends into a position between the plastic bags 20, 22, as shown in more detail in FIG. 2.
  • the shaft 42 carries at its end a crank or another eccentric 44, which describes a circular movement when the shaft 42 rotates and alternately compresses the lower and the upper plastic bags 20, 22 in the edge region thereof.
  • the temperature control medium within the bags 20, 22 is shifted to the left in FIG. 2, so that the temperature control medium in the entire plastic bags starts to vibrate, which is communicated to the plasma bag 38. This also causes the plasma to vibrate, so that the mentioned advantage of be particularly rapid temperature distribution within the plasma results.
  • Reinforcements 46, 48 can be provided on the edges of the plastic bags 20, 22 acted upon by the eccentric 44, which reinforcements reduce the wear when the eccentric 44 acts.
  • the eccentric 44 can also have a wear-preventing coating, for example made of polytetrafluoroethylene.
  • the reinforcements 46, 48 can run in strips or in another form over partial areas of the plastic bags 20, 22 and consist of relatively rigid material, so that the pressure exerted is distributed over a larger area of the plastic bags.

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • External Artificial Organs (AREA)

Abstract

A thawing and warming-up device for medical products, in particular for deep frozen preserved plasma or blood, contains at least two plastic bags (20, 22), containing a warmed-up medium, to be arranged on both sides of a product (38, 40) which is to be warmed up. A pressure member (42) acts regularly on at least one of the plastic bags, so that the warmed-up medium and hence the medical product are caused to execute a rocking motion. <IMAGE>

Description

Die Erfindung betrifft eine Auftau- und Temperiervorrich­tung für medizinische Produkte, insbesondere für tiefge­frorene Plasma- oder Blutkonserven, mit wenigstens zwei ein temperiertes Medium enthaltenden, beidseitig eines zu temperierenden Produkts anzuordnenden Kunststoffbeuteln.The invention relates to a thawing and tempering device for medical products, in particular for frozen plasma or blood preserves, with at least two plastic bags containing a tempered medium and to be arranged on both sides of a product to be tempered.

Eine derartige Vorrichtung ist aus dem DE-GM 86 06 622 des Anemlders bekannt. Zahlreiche medizinische Produkte, insbesondere Plasmalösungen oder Blutkonserven, werden bei minus 20°C in Tiefkühlschränken oder -truhen gelagert und müssen bei Bedarf auf der Krankenstation innerhalb kurzer Zeit auf z.B. 37°C erwärmt werden. Dabei ist eine örtliche Überhitzung der Konserve zu vermeiden, da sie etwa bei Blutkonserven zu einer Gerinnung oder bei anderen Konser­ven zu unerwünschten chemischen Reaktionen führen kann.Such a device is known from DE-GM 86 06 622 of the applicant. Numerous medical products, especially plasma solutions or blood preserves, are stored in freezers or freezers at minus 20 ° C and, if necessary, have to be quickly transferred to e.g. 37 ° C to be heated. Local overheating of the preserve should be avoided, since it can lead to coagulation in the case of blood preserves or undesirable chemical reactions in other preserves.

In der Praxis weit verbreitet ist die Verwendung eines Wasserbades zum Auftauen von tiefgefrorenen Produkten, je­doch ermöglicht warmes Wasser von ca. 37°C eine geradezu sprunghafte Vermehrung von Bakterien, Viren und Pilzen, die auf den Plasmabeutel übertragen und auch anderweitig verschleppt werden. Demgegenüber wird durch das obige Ge­brauchsmuster der Vorteil erreicht, daß die Konserve trok­ken, also ohne Berührung mit einem Wasserbad temperiert werden kann, so daß die Gefahr der Ausbreitung von Bakte­rien, Viren und Pilzen stark eingeschränkt wird. Trotzdem ermöglicht die Verwendung von zwei mit warmem Wasser oder einem anderen Temperiermedium gefüllten Beutel, die die Konserve großflächig und eng umschließen, einen ähnlich raschen Wärmeübergang, wie es bei Wasserbädern der Fall ist. Die erreichbaren Temperierzeiten sind also verhält­nismäßig kurz, wenngleich eine weitere Verkürzung natur­gemäß wünschenswert wäre.In practice, the use of a water bath for thawing frozen products is widespread, but warm water at approx. 37 ° C enables an almost abrupt increase in bacteria, viruses and fungi, which are transferred to the plasma bag and also carried over in other ways. In contrast, the above utility model has the advantage that the preserve can be dried, that is to say tempered without contact with a water bath, so that the risk of the spread of bacteria, viruses and fungi is greatly restricted. Nevertheless, the use of two bags filled with warm water or another tempering medium, which enclose the canned food over a large area and closely, enables heat to be transferred quickly, as is the case with water baths. The temperature control times that can be achieved are therefore relatively short, although a further reduction would naturally be desirable.

Der Erfindung liegt die Aufgabe zugrunde, eine Vorrich­tung zu schaffen, die es ermöglicht, die Temperierge­schwindigkeit gegenüber der bekannten Vorrichtung weiter zu steigern, ohne daß die Gefahr einer Überhitzung und Beschädigung des Produkts besteht.The invention has for its object to provide a device that makes it possible to further increase the temperature control compared to the known device without the risk of overheating and damage to the product.

Diese Aufgabe wird erfindungsgemäß bei einer Vorrichtung der eingangs genannten Art gelöst durch wenigstens ein periodisch auf wenigstens einen der Kunststoffbeutel ein­wirkendes Druckglied.This object is achieved according to the invention in a device of the type mentioned at the outset by at least one pressure member which acts periodically on at least one of the plastic bags.

Durch das Druckglied wird das Temperiermedium in dem Kunststoffbeutel in Schwingungen versetzt, so daß eine Schaukelbewegung entsteht, die sich dem medizinischen Pro­dukt, beispielsweise einem Plasmabeutel mitteilt. Dadurch gerät auch das Produkt in Bewegung, so daß der Temperatur­ausgleich von außen nach innen und über das gesamte Pro­dukt beschleunigt wird. Es wird daher eine gleichmäßige und rasche Bewegung ohne örtliche Überhitzungen erreicht. Unter Umständen besteht sogar die Möglichkeit, die Tem­peratur des Temperiermediums gegenüber der angestrebten Endtemperatur des Produkts in gewissen Grenzen zu erhöhen und damit eine weitere Beschleunigung zu erzielen, da durch die Schaukelbewegung und den raschen Temperaturaus­gleich örtliche Überhitzungen an der Außenfläche des Produkts vermieden werden können.The temperature control medium in the plastic bag is caused to vibrate by the pressure member, so that a rocking movement occurs, which is communicated to the medical product, for example a plasma bag. This also causes the product to move so that the temperature equalization is accelerated from the outside in and across the entire product. A smooth and rapid movement without local overheating is therefore achieved. Under certain circumstances, it is even possible to increase the temperature of the temperature control medium within certain limits compared to the desired end temperature of the product and thus achieve further acceleration, since local overheating on the outer surface of the product can be avoided through the rocking movement and the rapid temperature compensation.

Vorzugsweise weist die Vorrichtung zwei aufeinander liegen­de, im wesentlichen deckungsgleiche, mit dem temperierten Medium gefüllte Kunststoffbeutel auf, zwischen die das zu temperierende Produkt nach Abheben des oberen Beutels gelegt wird, und das Druckglied besteht aus einem zwi­schen die Kunststoffbeutel eintretenden, drehbaren Exzen­ter, der abwechselnd auf die Kunststoffbeutel einwirkt.Preferably, the device has two superimposed, essentially congruent, plastic bags filled with the temperature-controlled medium, between which the product to be temperature-controlled is placed after the upper bag has been lifted off, and the pressure element consists of a rotating eccentric that enters between the plastic bags and which alternates acts on the plastic bag.

Bei einer Vorrichtung der angegebenen Art, bei der die Kunststoffbeutel ein mit Hilfe einer Pumpe umgewälztes, temperiertes Medium enthalten, wird vorzugsweise der In­nendruck bzw. Füllungsgrad der Kunststoffbeutel während eines Schaukelvorganges abgesenkt. Auf diese Weise läßt sich das temperierte Medium leichter in Schwingungen ver­setzen, als es bei einem prall gefüllten Beutel der Fall ist.In a device of the type specified, in which the Plastic bags contain a temperature-controlled medium circulated with the aid of a pump, the internal pressure or degree of filling of the plastic bags is preferably reduced during a rocking operation. In this way, the temperature-controlled medium can be set into vibration more easily than is the case with a bulging bag.

Entsprechend einer vorteilhaften Ausführungsform der Erfin­dung wirkt das Druckglied auf einen Randbereich des oder der Kunststoffbeutel ein. Dies hat nicht nur den Vorteil, daß der mittlere Bereich der Kunststoffbeutel als Berüh­rungsfläche für das medizinische Produkt zur Verfügung steht, sondern von einem Rand der Kunststoffbeutel her lassen sich im übrigen auch die angestrebten Schwingungen zuverlässiger erzielen. Im Bereich der Einwirkung des Druckgliedes können die Kunststoffbeutel eine Verstärkung aufweisen, die den Verschleiß verringert und im übrigen auch flächig ausgebildet sein kann, so daß sie den Druck des Druckgliedes über eine größere Fläche der Kunststoff­beutel verteilt.According to an advantageous embodiment of the invention, the pressure member acts on an edge region of the plastic bag or bags. This not only has the advantage that the central area of the plastic bag is available as a contact surface for the medical product, but the desired vibrations can also be achieved more reliably from an edge of the plastic bag. In the area of action of the pressure member, the plastic bags can have a reinforcement that reduces wear and can also be flat, so that it distributes the pressure of the pressure member over a larger area of the plastic bags.

Im folgenden werden bevorzugte Ausführungsbeispiele der Erfindung anhand der beigefügten Zeichnung näher erläutert.

  • Fig. 1 ist eine perspektivische, teilweise aufgebrochene Gesamtdarstellung einer erfindungsgemäßen Vorrichtung;
  • Fig. 2 ist ein schematischer Längsschnitt durch die Vorrichtung.
Preferred exemplary embodiments of the invention are explained in more detail below with reference to the attached drawing.
  • 1 is an overall perspective view, partially broken away, of a device according to the invention;
  • Fig. 2 is a schematic longitudinal section through the device.

Fig. 1 zeigt eine erfindungsgemäße Vorrichtung mit einem kastenförmigen Gehäuse 10, an dessen Oberseite ein auf­klappbarer Deckel 12 vorgesehen ist. Das Innere des Gehäu­ses ist durch eine waagerechte Platte 14 in eine obere Temperierkammer 16 und eine untere Warmwasserkammer 18 unterteilt.Fig. 1 shows a device according to the invention with a box-shaped housing 10, on the top of which a hinged lid 12 is provided. The inside of the housing is through a horizontal plate 14 in an upper Temperature control chamber 16 and a lower hot water chamber 18 divided.

In der Temperierkammer 16 liegt auf der Platte 14 ein rechteckiger Kunststoffbeutel 20 und auf diesem ein im wesentlichen deckungsgleicher, in Fig. 1 zurückgeklappt gezeigter Kunststoffbeutel 22. Die Kunststoffbeutel be­stehen beispielsweise aus einem weichen, temperaturbestän­digen Material wie z.B. PVC. Beide Kunststoffbeutel weisen Schlauchanschlüsse 24,26,28,30 auf, die jeweils paarweise Ein- und Auslaß der beiden Kunststoffbeutel 20,22 bilden. Die Schlauchanschlüsse 24,26,28,30 sind in nicht gezeigter Weise mit einer Pumpe 32 verbunden, die warmes Wasser aus der Warmwasserkammer 18 durch die Kunststoffbeuteil 20, 22 umwälzt. Dabei sind die Schlauchanschlüsse der Kunst­stoffbeutel gegenläufig geschaltet, so daß beispielsweise die Schlauchanschlüsse 24,26, die links in Fig. 1 gezeigt sind, für den unteren Kunststoffbeutel den Einlaß und für den oberen Kunststoffbeutel den Auslaß bilden. Dadurch wird die Wirkung eines in den Kunststoffbeuteln auftreten­den Temperaturabfalls ausgeglichen.In the temperature control chamber 16 there is a rectangular plastic bag 20 on the plate 14 and on this a substantially congruent plastic bag 22 shown folded back in FIG. 1. The plastic bags consist for example of a soft, temperature-resistant material such as e.g. PVC. Both plastic bags have hose connections 24, 26, 28, 30, which form the inlet and outlet of the two plastic bags 20, 22 in pairs. The hose connections 24, 26, 28, 30 are connected in a manner not shown to a pump 32, which circulates hot water from the hot water chamber 18 through the plastic bag parts 20, 22. The hose connections of the plastic bags are connected in opposite directions, so that for example the hose connections 24, 26, which are shown on the left in FIG. 1, form the inlet for the lower plastic bag and the outlet for the upper plastic bag. This compensates for the effect of a temperature drop occurring in the plastic bags.

In der Warmwasserkammer 18, in der sich trotz dieser Be­zeichnung auch ein anderes Temperiermedium befinden kann, sind Heizschlangen 34 vorgesehen, die in Verbindung mit einer an der Stirnseite des Gehäuses 10 angeordneten Steuerelektronik 36 eine vollständig gleichmäßige und genaue Temperatureinstellung des Temperiermediums ermöglichen.In the hot water chamber 18, in which, despite this designation, there can also be another temperature control medium, heating coils 34 are provided which, in conjunction with control electronics 36 arranged on the end face of the housing 10, enable a completely uniform and precise temperature setting of the temperature control medium.

Bei Anwendung der erfindungsgemäßen Vorrichtung etwa zur Erwärmung von Plasmabeuteln 38,40 wird der obere Kunst­stoffbeutel 22 hochgehoben, die Plasmabeutel werden auf den unteren Kunststoffbeutel 20 aufgelegt, und der obere Kunststoffbeutel 22 wird wiederum auf die Plasmabeutel aufgelegt. Aufgrund des weichen Materials der Kunststoff­beutel schließen diese sich eng und flächig an die Plasma­ beutel an, so daß eine rasche Wärmeübertragung stattfinden kann.When using the device according to the invention, for example for heating plasma bags 38, 40, the upper plastic bag 22 is lifted up, the plasma bags are placed on the lower plastic bag 20, and the upper plastic bag 22 is again placed on the plasma bags. Due to the soft material of the plastic bags, they close closely to the plasma bag so that rapid heat transfer can take place.

Während des Temperiervorganges bleiben die Plasmabeutel vollständig trocken. Da das warme Wasser innerhalb eines geschlossenen Systems verbleibt und mit dem medizinischen Produkt nicht in Berührung kommt, ist es nicht erforder­lich, nach jeder Benutzung das Wassersystem zu reinigen und zu sterilisieren. Für den Fall, daß die Kunststoffbeu­tel 20,22 ausnahmsweise Leckstellen aufweisen sollten, ist die Temperierkammer 16 zusammen mit der Platte 14 vorzugsweise als wasserdichte Auffangwanne ausgebildet, in der Flüssigkeitsspuren rasch bemerkt werden können, so daß deren Ursache beseitigt werden kann.The plasma bags remain completely dry during the tempering process. Since the warm water remains within a closed system and does not come into contact with the medical product, it is not necessary to clean and sterilize the water system after each use. In the event that the plastic bags 20, 22 should have leakages as an exception, the temperature control chamber 16, together with the plate 14, is preferably designed as a watertight collecting trough, in which traces of liquid can be quickly noticed, so that the cause thereof can be eliminated.

Entgegen der in Fig. 1 gezeigten Ausführungsform kann der obere Kunststoffbeutel 22 an dem Deckel 12 aufgehängt sein, so daß er beim Öffnen des Deckels automatisch angehoben wird.Contrary to the embodiment shown in Fig. 1, the upper plastic bag 22 can be suspended from the lid 12 so that it is automatically raised when the lid is opened.

Aus der rückwärtigen Wand der Temperierkammer 16, bezogen auf Fig. 1, tritt zwischen den Schlauchanschlüssen 24,26 sowie 28,30 eine Welle 42 aus, die außerhalb der Temperier­kammer 16 mit einem nicht gezeigten Antriebsmotor verbun­den ist. Die Welle 42 erstreckt sich in eine Position zwi­schen den Kunststoffbeuteln 20,22, wie in Fig. 2 näher ge­zeigt ist. Zwischen den Kunststoffbeuteln 20,22 trägt die Welle 42 an ihrem Ende eine Kurbel oder einen sonstigen Exzenter 44, der bei Drehung der Welle 42 eine Kreisbewe­gung beschreibt und dabei abwechselnd den unteren und den oberen Kunststoffbeutel 20,22 in dessen Randbereich zu­sammendrückt. Durch dieses Zusammendrücken wird das Tempe­riermedium innerhalb der Beutel 20,22 nach links in Fig. 2 verschoben, so daß das Temperiermedium in den gesamten Kunststoffbeuteln in Schwingungen gerät, die sich dem Plasmabeutel 38 mitteilen. Dadurch gerät auch das Plasma in Schwingung, so daß sich der erwähnte Vorteil einer be­ sonders raschen Temperaturverteilung innerhalb des Plasma ergibt.From the rear wall of the temperature control chamber 16, based on FIG. 1, a shaft 42 emerges between the hose connections 24, 26 and 28, 30 and is connected to a drive motor (not shown) outside the temperature control chamber 16. The shaft 42 extends into a position between the plastic bags 20, 22, as shown in more detail in FIG. 2. Between the plastic bags 20, 22, the shaft 42 carries at its end a crank or another eccentric 44, which describes a circular movement when the shaft 42 rotates and alternately compresses the lower and the upper plastic bags 20, 22 in the edge region thereof. As a result of this compression, the temperature control medium within the bags 20, 22 is shifted to the left in FIG. 2, so that the temperature control medium in the entire plastic bags starts to vibrate, which is communicated to the plasma bag 38. This also causes the plasma to vibrate, so that the mentioned advantage of be particularly rapid temperature distribution within the plasma results.

An den von dem Exzenter 44 beaufschlagten Rändern der Kunststoffbeutel 20,22 können Verstärkungen 46,48 vorge­sehen sein, die den Verschleiß bei Einwirkung des Exzen­ters 44 verringern. Der Exzenter 44 kann im übrigen auch einen verschleißhindernden Überzug, etwa aus Polytetrafluor­äthylen aufweisen. Die Verstärkungen 46,48 können streifen­förmig oder in anderer Form über Teilflächen der Kunststoff­beutel 20,22 hinweg verlaufen und aus relativ steifem Ma­terial bestehen, so daß sich der ausgeübte Druck auf eine größere Fläche der Kunststoffbeutel verteilt.Reinforcements 46, 48 can be provided on the edges of the plastic bags 20, 22 acted upon by the eccentric 44, which reinforcements reduce the wear when the eccentric 44 acts. The eccentric 44 can also have a wear-preventing coating, for example made of polytetrafluoroethylene. The reinforcements 46, 48 can run in strips or in another form over partial areas of the plastic bags 20, 22 and consist of relatively rigid material, so that the pressure exerted is distributed over a larger area of the plastic bags.

Claims (8)

1. Auftau- und Temperiervorrichtung für medizinische Produkte, insbesondere für tiefgefrorene Plasma- oder Blutkonserven, mit wenigstens zwei ein temperiertes Medium enthaltenden, beidsei­tig eines zu temperierenden Produkts anzuordnenden Kunststoff­beuteln, gekennzeichnet durch wenigstens ein periodisch auf wenigstens einen der Kunststoffbeutel (20,22) einwirkendes Druckglied (42,44).1. Thawing and tempering device for medical products, in particular for frozen plasma or blood preserves, with at least two plastic bags containing a tempered medium, to be arranged on both sides of a product to be tempered, characterized by at least one periodically acting on at least one of the plastic bags (20, 22) Pressure member (42.44). 2. Auftau- und Temperiervorrichtung nach Anspruch 1, mit zwei aufeinander liegenden, im wesentlichen deckungsgleichen, mit dem temperierten Medium gefüllten Kunststoffbeuteln, dadurch gekennzeichnet, daß das Druckglied einen zwischen die Kunststoffbeutel (20,22) eintretenden, um­laufenden, alternativ auf einen der Kunststoffbeutel (20,­22) einwirkenden Exzenter (44) umfaßt.2. Thawing and tempering device according to claim 1, with two superimposed, substantially congruent, filled with the tempered medium plastic bags, characterized in that the pressure member between the plastic bags (20, 22) entering, rotating, alternatively acting on one of the plastic bags (20, 22) eccentric (44). 3. Auftau- und Temperiervorrichtung nach Anspruch 1 oder 2, bei der durch die Kunststoffbeutel ein flüssiges, tem­periertes Medium mit Hilfe einer Pumpe umgewälzt wird, dadurch gekennzeichnet, daß der Innendruck bzw. Füllungsgrad der Kunststoffbeutel (20,22) veränderbar ist.3. Thawing and tempering device according to claim 1 or 2, in which a liquid, tempered medium is circulated by means of a pump through the plastic bag, characterized in that the internal pressure or degree of filling of the plastic bag (20, 22) is variable. 4. Auftau- und Temperiervorrichtung nach Anspruch 3, da­durch gekennzeichnet, daß der Pumpenausgangs­druck veränderbar ist.4. defrosting and temperature control device according to claim 3, characterized in that the pump outlet pressure is variable. 5. Auftau- und Temperiervorrichtung nach einem der vor­hergehenden Ansprüche, dadurch gekennzeichnet, daß das Druckglied (42,44) auf Randbereiche der Kunststoff­beutel (20,22) einwirkt.5. defrosting and temperature control device according to one of the preceding claims, characterized in that the pressure member (42,44) acts on edge regions of the plastic bag (20,22). 6. Auftau- und Temperiervorrichtung nach einem der vor­hergehenden Ansprüche, dadurch gekennzeichnet, daß die Kunststoffbeutel (20,22) im Bereich der Einwirkung das Druckgliedes (42,44) eine Verstärkung (46,48) aufweisen.6. Thawing and temperature control device according to one of the preceding claims, characterized in that the plastic bags (20, 22) have a reinforcement (46, 48) in the region of the action of the pressure member (42, 44). 7. Auftau- und Temperiervorrichtung nach Anspruch 6, da­durch gekennzeichnet, daß die Verstärkung (46,48) aus verhältnismäßig steifem Material besteht und sich streifenförmig über die Kunststoffbeutel (20,22) er­streckt.7. defrosting and tempering device according to claim 6, characterized in that the reinforcement (46,48) consists of relatively rigid material and extends in strips over the plastic bag (20,22). 8. Auftau- und Temperiervorrichtung nach einem der vorher­gehenden Ansprüche, mit einer Steuervorrichtung zur selbst­tätigen Steuerung eines Temperiervorganges, dadurch ge­kennzeichnet, daß die Tätigkeit des Druckgliedes (42,44) steuerungstechnisch gekoppelt ist mit einer Re­duzierung des Pumpenausgangsdrucks der Pumpe (32).8. Thawing and temperature control device according to one of the preceding claims, with a control device for automatically controlling a temperature control process, characterized in that the activity of the pressure member (42,44) is coupled in terms of control technology with a reduction in the pump outlet pressure of the pump (32).
EP88119889A 1987-12-04 1988-11-29 Thawing and warming-up device for medical products Expired - Lifetime EP0318924B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT88119889T ATE73678T1 (en) 1987-12-04 1988-11-29 THAWING AND TEMPERATURE CONTROL DEVICE FOR MEDICAL PRODUCTS.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3741051A DE3741051C1 (en) 1987-12-04 1987-12-04 Thawing and tempering device for medical products
DE3741051 1987-12-04

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EP0318924A1 true EP0318924A1 (en) 1989-06-07
EP0318924B1 EP0318924B1 (en) 1992-03-18

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AT (1) ATE73678T1 (en)
DE (2) DE3741051C1 (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0432591A1 (en) * 1989-12-07 1991-06-19 TRANSMED Medizintechnik GmbH Warming up and thawing device
AT1650U1 (en) * 1996-06-26 1997-09-25 Immuno Ag METHOD AND DEVICE FOR APPLYING A FROZEN PLASMA PRODUCT
WO2002004052A1 (en) * 2000-07-07 2002-01-17 Transmed Medizintechnik Gmbh & Co. Kg Device for defrosting and/or heating up
NL1015794C2 (en) * 2000-07-25 2002-01-28 Gert Van Riessen Heating device for an infusion liquid in a dosing package.
US6786054B2 (en) 2001-05-22 2004-09-07 Integrated Biosystems, Inc. Systems and methods for freezing, storing and thawing biopharmaceutical material
CN105999444A (en) * 2016-04-27 2016-10-12 北京诚名扬科技发展有限公司 Dry-type blood plasma unfreezing instrument
WO2019223828A1 (en) 2018-05-22 2019-11-28 Barkey Gmbh & Co. Kg Temperature-control device and temperature-control method
US11571699B2 (en) 2018-03-13 2023-02-07 Terumo Kabushiki Kaisha Melting device and melting method

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3821299A1 (en) * 1988-06-24 1989-11-09 Litterst Werner Alfons Electrical temperature-control systems with or without feedback for containers made of glass, plastic or metal with shaped, flexible heater
DE4230774A1 (en) * 1992-09-15 1994-03-17 Wwt Tech Geraetebau Gmbh Device for handling substances stored in deformable containers
DE19548826C2 (en) * 1995-12-27 1999-10-28 Guenther Schmidt Rapid electrical defrosting device and method for rapid defrosting of frozen liquids
DE19730994A1 (en) * 1997-07-18 1999-02-11 Transmed Medtech Gmbh Device for thawing and / or heating medical infusion or transfusion material in a container
DE10053132C1 (en) * 2000-10-26 2002-04-11 Reimer Wiepcke Heating box has lid with hinge mobility/lid weight enabling gap to form under pressure in box to allow used air out when connector supplied with normal flow of hot air from patient heater
US6748164B1 (en) 2000-10-31 2004-06-08 Photo-Therm, L.P. Plasma thawing system
US7722839B2 (en) 2001-10-11 2010-05-25 Cytotherm, L.P. Apparatus and method for thawing biological materials
US8012416B2 (en) 2005-08-30 2011-09-06 Cytotherm, L.P. Thawing biological material using a sealed liquid bladder
EP2012585B1 (en) 2006-03-06 2016-11-02 Sartorius Stedim North America Inc. Systems and methods for freezing, storing and thawing biopharmaceutical materials
DE202010004830U1 (en) 2010-04-10 2010-07-29 Pelster, Michael, Dipl.-Ing. Device for thawing and / or heating medical goods in a container
CN102416205A (en) * 2011-08-02 2012-04-18 董喜春 Dry type plasma thawing instrument
CN105263611B (en) * 2013-05-07 2018-05-08 生物安全股份有限公司 Hybrid system for mixed biologic sample and additive
CA2957526C (en) 2014-08-08 2023-03-28 Fremon Scientific, Inc. Smart bag used in sensing physiological and/or physical parameters of bags containing biological substance
CA3099276A1 (en) 2018-05-07 2019-11-14 Fremon Scientific, Inc. Thawing biological substances

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3518393A (en) * 1967-11-21 1970-06-30 South African Inventions Bloodwarmers
US4473739A (en) * 1980-12-18 1984-09-25 Helmholtz-Institut Fur Biomedizinische Technik Process and apparatus for warming of suspensions or solutions frozen in a flat plastic bag
DE8606622U1 (en) * 1986-03-11 1986-10-30 Barkey, Volker, 4800 Bielefeld Thawing and temperature control device for medical products

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3518393A (en) * 1967-11-21 1970-06-30 South African Inventions Bloodwarmers
US4473739A (en) * 1980-12-18 1984-09-25 Helmholtz-Institut Fur Biomedizinische Technik Process and apparatus for warming of suspensions or solutions frozen in a flat plastic bag
DE8606622U1 (en) * 1986-03-11 1986-10-30 Barkey, Volker, 4800 Bielefeld Thawing and temperature control device for medical products

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0432591A1 (en) * 1989-12-07 1991-06-19 TRANSMED Medizintechnik GmbH Warming up and thawing device
AT1650U1 (en) * 1996-06-26 1997-09-25 Immuno Ag METHOD AND DEVICE FOR APPLYING A FROZEN PLASMA PRODUCT
US5829634A (en) * 1996-06-26 1998-11-03 Immuno Aktiengesellschaft Method of discharging a frozen blood product
WO2002004052A1 (en) * 2000-07-07 2002-01-17 Transmed Medizintechnik Gmbh & Co. Kg Device for defrosting and/or heating up
US6861624B1 (en) 2000-07-07 2005-03-01 Transmed Medizintechnik Gmbh & Co. Kg Device for defrosting and/or heating up
NL1015794C2 (en) * 2000-07-25 2002-01-28 Gert Van Riessen Heating device for an infusion liquid in a dosing package.
WO2002013894A1 (en) * 2000-07-25 2002-02-21 Gert Van Riessen Heating device for an infusion liquid in a dispensing packaging
US6786054B2 (en) 2001-05-22 2004-09-07 Integrated Biosystems, Inc. Systems and methods for freezing, storing and thawing biopharmaceutical material
CN105999444A (en) * 2016-04-27 2016-10-12 北京诚名扬科技发展有限公司 Dry-type blood plasma unfreezing instrument
CN105999444B (en) * 2016-04-27 2018-06-29 北京诚名扬科技发展有限公司 Dry blood plasma unfreezing apparatus
US11571699B2 (en) 2018-03-13 2023-02-07 Terumo Kabushiki Kaisha Melting device and melting method
WO2019223828A1 (en) 2018-05-22 2019-11-28 Barkey Gmbh & Co. Kg Temperature-control device and temperature-control method

Also Published As

Publication number Publication date
EP0318924B1 (en) 1992-03-18
DE3741051C1 (en) 1989-06-01
DE3869348D1 (en) 1992-04-23
ATE73678T1 (en) 1992-04-15

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