EP0304486A4 - Production of bioadhesive precursor protein analogs by genetically-engineered organisms - Google Patents

Production of bioadhesive precursor protein analogs by genetically-engineered organisms

Info

Publication number
EP0304486A4
EP0304486A4 EP19880903582 EP88903582A EP0304486A4 EP 0304486 A4 EP0304486 A4 EP 0304486A4 EP 19880903582 EP19880903582 EP 19880903582 EP 88903582 A EP88903582 A EP 88903582A EP 0304486 A4 EP0304486 A4 EP 0304486A4
Authority
EP
European Patent Office
Prior art keywords
genetically
production
precursor protein
protein analogs
engineered organisms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19880903582
Other versions
EP0304486A1 (en
Inventor
Kathy J. Maugh
David M. Anderson
Susan L. Strausberg
Robert Strausberg
Tena Wei
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genex Corp
Original Assignee
Genex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genex Corp filed Critical Genex Corp
Publication of EP0304486A1 publication Critical patent/EP0304486A1/en
Publication of EP0304486A4 publication Critical patent/EP0304486A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
EP19880903582 1987-03-12 1988-03-11 Production of bioadhesive precursor protein analogs by genetically-engineered organisms Withdrawn EP0304486A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2524387A 1987-03-12 1987-03-12
US25243 1987-03-12

Publications (2)

Publication Number Publication Date
EP0304486A1 EP0304486A1 (en) 1989-03-01
EP0304486A4 true EP0304486A4 (en) 1990-12-05

Family

ID=21824898

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19880903582 Withdrawn EP0304486A4 (en) 1987-03-12 1988-03-11 Production of bioadhesive precursor protein analogs by genetically-engineered organisms

Country Status (4)

Country Link
EP (1) EP0304486A4 (en)
JP (1) JPH02500082A (en)
AU (1) AU1572588A (en)
WO (1) WO1988007076A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5849537A (en) * 1989-09-19 1998-12-15 Miller Brewing Company Method of expressing antifreeze proteins in yeast
US5197973A (en) * 1990-12-14 1993-03-30 Creative Biomolecules, Inc. Synthetic bioadhesive
US5605938A (en) * 1991-05-31 1997-02-25 Gliatech, Inc. Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate
US5674728A (en) * 1993-11-03 1997-10-07 Novartis Corporation Aspergillus niger vacuolar aspartyl protease
AU5910099A (en) * 1998-09-09 2000-04-03 United States Surgical Corporation Recombinant bioadhesive protein analogs comprising hydroxyproline
DE102004031258A1 (en) * 2004-06-29 2006-02-09 Jennissen, Herbert P., Prof. Dr. Protein hybrids with polyhydroxyaromatic amino acid epitopes
US6987170B1 (en) * 2004-08-09 2006-01-17 Battelle Energy Alliance, Llc Cloning and expression of recombinant adhesive protein Mefp-1 of the blue mussel, Mytilus edulis
US9688735B2 (en) 2010-08-20 2017-06-27 Wyeth Llc Designer osteogenic proteins
BR112020022260A2 (en) * 2018-04-30 2021-02-23 Perfect Day, Inc recombinant milk protein polymers
WO2021047648A1 (en) * 2019-09-14 2021-03-18 Jiangyin Usun Pharmaceutical Co., Ltd. New peptides
GB202018608D0 (en) * 2020-11-26 2021-01-13 Zentraza Ltd Adhesive peptides

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0242656A2 (en) * 1986-04-25 1987-10-28 Bio-Polymers, Inc. Method for making dopa-containing bioadhesive proteins from tyroshine-containing proteins
WO1988003953A1 (en) * 1986-11-24 1988-06-02 Genex Corporation Bioadhesives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4585585A (en) * 1984-03-07 1986-04-29 University Of Connecticut Research & Development Corporation Decapeptides produced from bioadhesive polyphenolic proteins
US4687740A (en) * 1984-03-07 1987-08-18 University Of Connecticut Research & Development Corp. Decapeptides produced from bioadhesive polyphenolic proteins
IT1228422B (en) * 1987-07-16 1991-06-17 Montefibre Spa POLYESTER FIBERS AND GLASS FIBERS AND FABRICS AND NONWOVEN FABRICS AND PROCEDURE TO OBTAIN THEM.

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0242656A2 (en) * 1986-04-25 1987-10-28 Bio-Polymers, Inc. Method for making dopa-containing bioadhesive proteins from tyroshine-containing proteins
WO1988003953A1 (en) * 1986-11-24 1988-06-02 Genex Corporation Bioadhesives

Non-Patent Citations (10)

* Cited by examiner, † Cited by third party
Title
BIOCHEMISTRY, vol. 24, 1985, pages 5010-5014, American Chemical Society; J.H. WAITE et al.: "Peptide repeats in a mussel glue protein: theme and variations" *
BIOCHIM. BIOPHYS. ACTA 1986, vol. 872, nos. 1-2, pages 98-103; K. MARUMO et al.: "Optimization of hydroxylation of tyrosine and tyrosine-containing peptides by mushroom tyrosinase" *
CHEMICAL ABSTRACTS, vol. 100, no. 11, 12th March 1984, page 194, abstract no. 81483t, Columbus, Ohio, US; G.H. ENGEBRETSON et al.: "Isolation of adhesive proteins secreted by the sea mussel, mytilus edulis", & COMP. BIOCHEM. PHYSIOL., B: COMP. BIOCHEM. 1984, 77B(1), 201-5 *
CHEMICAL ABSTRACTS, vol. 105, no. 21, 24th November 1986, page 315, abstract no. 186489f, Columbus, Ohio, US; K. MARUMO et al.: "Optimization of hydroxylation of tyrosine and tyrosine-containing peptides by mushroom tyrosinase", & BIOCHIM, BIOPHYS. ACTA 1986, 872(1-2), 98-103 *
CHEMICAL ABSTRACTS, vol. 110, no. 5, 30th January 1989, abstract no. 44875h, Columbus, Ohio, US; K. MARUMO et al.: "Preparation and purification of adhesive protein from marine mussel, mytilus edulis L", & KETSUGO SOSHIKI 1987, 19(3-4), 280-1 *
COMP. BIOCHEM. PHYSIOL., B: COMP. BIOCHEM. 1984, 77B(1), 201-5; G.H. ENGEBRETSON et al.: "Isolation of adhesive proteins secreted by the sea mussel, mytilus edulis" *
GENETIC ENGINEERING NEWS, 14th April 1985, pages 14-18; R. JOHNSON: "Genex seeks to clone mussel glue protein" *
J. COMP. PHYSIOL. B, vol. 156, 1986, pages 491-496, Springer-Verlag; J.H. WAITE: "Mussel glue from mytilus californiamus conrad: a comparative study" *
See also references of WO8807076A1 *
THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 258, no. 6, 14th March 1983, pages 2911-2915, US; J.H. WAITE: "Evidence for a repeating 3,4-dihydroxyphenylalanine- and hydroxyproline-containing decapeptide in the adhesive protein of the mussel, mytilus edulis L" *

Also Published As

Publication number Publication date
EP0304486A1 (en) 1989-03-01
AU1572588A (en) 1988-10-10
WO1988007076A1 (en) 1988-09-22
JPH02500082A (en) 1990-01-18

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Legal Events

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Effective date: 19930703