EP0291658A1 - Closure cap for infusion and transfusion bottles - Google Patents

Closure cap for infusion and transfusion bottles Download PDF

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Publication number
EP0291658A1
EP0291658A1 EP88104448A EP88104448A EP0291658A1 EP 0291658 A1 EP0291658 A1 EP 0291658A1 EP 88104448 A EP88104448 A EP 88104448A EP 88104448 A EP88104448 A EP 88104448A EP 0291658 A1 EP0291658 A1 EP 0291658A1
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EP
European Patent Office
Prior art keywords
cap
plastic cover
edge
cap according
central recess
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP88104448A
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German (de)
French (fr)
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EP0291658B1 (en
Inventor
Alfred Von Schuckmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pohl GmbH and Co KG
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Pohl GmbH and Co KG
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Publication date
Application filed by Pohl GmbH and Co KG filed Critical Pohl GmbH and Co KG
Priority to AT88104448T priority Critical patent/ATE64864T1/en
Publication of EP0291658A1 publication Critical patent/EP0291658A1/en
Application granted granted Critical
Publication of EP0291658B1 publication Critical patent/EP0291658B1/en
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/002—Closures to be pierced by an extracting-device for the contents and fixed on the container by separate retaining means

Definitions

  • the invention relates to a closure cap for infusion and transfusion bottles, with a flanged cap encircling a flanged neck of the bottle, which has a central recess which is closed by the central region of a plastic cover in such a way that an annular zone of the plastic cover engages under the edge of the central recess .
  • a closure cap of this type is known from DE-PS 20 40 937.
  • the central recess is exposed for the insertion of an injection needle, a transfusion set or the like through a disc-like sealing plug embedded in the flared neck.
  • an effective germ barrier must be present, which is provided by an annular groove-like sealing joint.
  • the form-fitting encirclement of the central recess by the tough-elastic plastic of the cover requires relatively high opening forces, which is why a pull tab that is approximately matched to the area size of the central recess is molded onto the plastic cover.
  • the object of the invention is to provide a generic cap in a technically simple, more reliable manner without sacrificing tightness so that the cap can be removed more easily despite a stronger connection to the crimp cap.
  • a generic closure cap which takes into account the basic requirement of the aseptic seal, but can nevertheless be opened by the operating personnel using lower forces. This is easily achieved by at least one radially extending predetermined crease line of the plastic cover formed by thinning the material. When the edge of the plastic lid is grasped, it is simply folded up around it, defined by the said crease line. Since it intersects the central area, half of the ring zone of the connecting point sealingly surrounding the edge of the central recess is levered out, and the rest is slightly pulled out.
  • the opening aid described can be implemented several times on the closure cap, for example by means of a plurality of predetermined bend lines which are provided in a uniform angular distribution and extend from the edge of the plastic cover to the central area. This results in several main areas for the initiation of the lever-favorable folding up of the plastic cover with subsequent pulling out of the ring seal-side remaining sealing section.
  • the plastic cover has at least one grip tab projecting over the edge of the flange of the flange.
  • this grip tab can sit at the level of the bottom surface of the cup-shaped plastic lid.
  • the groove also extends through the ring zone, the area defined by it and the wall of the plastic cover. This also makes kinking easier.
  • the invention also provides an embodiment in such a way that a circumferential tear line is located outside the edge of the central recess, which is gripped by the ring zone, in the ceiling of the crimp cap.
  • a circumferential tear line is located outside the edge of the central recess, which is gripped by the ring zone, in the ceiling of the crimp cap.
  • the bottle 2 containing an infusion or transfusion liquid 1 merges into a so-called flared neck 3 via a section which tapers in the shape of a truncated cone.
  • the corresponding wall offset forms an inner annular shoulder 4 for supporting a disk-shaped sealing plug 5 on the edge.
  • This is made of rubber, plastic or other material that can be penetrated by a cannula and closes again.
  • the relatively thick-walled plug 5 closes with the end face 3 'of the flared neck 3 from substantially the same level.
  • the germ-inhibiting closure is formed by a sealing cap 6 resting thereon.
  • the latter consists of a pot-shaped crimping cap 7 with a central central recess 8, which is closed by a plastic cover 9.
  • the crimp cap 7 has a cylindrical pot wall, the edge of which engages under an annular shoulder 10 of the crimp neck 3.
  • the crimp cap 7 is made of relatively thin-walled aluminum.
  • the shoulder-flanging edge is designated 7 '.
  • the bottom of the cap forming the ceiling 11 of the cup-shaped crimp cap 7 is flat.
  • the edge of the central recess 8 arranged therein merges into an inverse flare, so that this edge is transversely rounded and is practically double-walled on a short radial section.
  • the ring collar created in this way bears the reference number 12. Its inside lies against the underside of the cover 11.
  • connection between the crimp cap 7 and the likewise cup-shaped plastic cover 9 can be made by thermal riveting or by spraying.
  • the plastic lid 9 forms a standing collar 13 pointing in the direction of the bottle, the outer diameter of which corresponds to the inside diameter of the circular central recess 8.
  • the cylindrically shaped stand-up collar 13 passes through said center recess 8 when assigned, after which the projecting collar portion 13 'is turned outwards.
  • the related connection area proves to be tight and thus an effective germ barrier. Basically, the edge of the central recess 8 then lies in an annular groove.
  • the outer wall of the crimp cap 7 is only partially overlapped by the cylindrical wall 9 'of the plastic cover 9, approximately over a third of the axial length.
  • the pot wall 9 'of the plastic cover 9 is many times thicker than that of the crimp cap 7. The same basically applies to the thickness of the ceiling 9' of the plastic cover 9.
  • the plastic cover 9 In order to use the infusion liquid 1, only the plastic cover 9 needs to be removed. This means removal of the connection between the latter and the crimp cap 7, which, with its annular surface, overlaps the sealing plug 5 in the edge region (that in FIGS. 5 and 9 shown gap-like distance is greatly exaggerated for reasons of clarity).
  • the corresponding loosening of the plastic cap 9 is facilitated by at least one radially extending nominal crease line xx of the plastic cover 9 formed by material thinning.
  • the nominal crease lines xx are formed by a groove 14. This is located on the underside 15 of the plastic Lid 9.
  • the grooves 14 begin at the level of the jacket wall of the central ring collar 13 and extend, seen in extension, diametrically extending, so cutting the longitudinal center axis yy of the rotationally symmetrical bottle 2, up to the cylindrical inner surface of the pot wall 9 '.
  • the groove can also be on the top of the cover.
  • the depth of the groove corresponds to approximately 4/5 of the thickness of the ceiling 9 ⁇ of the plastic cover 9.
  • the width of the groove 14 corresponds to the depth (see FIG. 7).
  • fold halves are produced when the angles are raised. It is based on an inexpensive long lever arm, which lifts the ring collar 13 forming the fastening section exactly in half. The rest of the excavation works accordingly without any great effort. This half can be pulled out practically parallel to the groove.
  • the plastic lid 9 has at least one grip tab 16 which projects horizontally over the flanged edge 7 'of the flared cap 7 (so it needs the quite narrow edge of the lid not to be caught). It is a cap-like, at the ceiling 9 ⁇ extending formations, which also leads to an even larger lever arm lead length.
  • the grip tabs 16 each protrude perpendicular to the diametrical nominal crease line xx. Their free ends are cut parallel to the line in question.
  • the grooves 14 can alternatively be continued in the circumscribed inner surface in the same direction and also include the pot wall 9 'of the plastic cover 9 (see FIG. 6, dot-dash lines) Registration).
  • the corresponding groove cuts through to the respective rim of the pot.
  • the corresponding top recess has the reference number 17. It can also be located below.
  • the remaining web corresponds to the thickness of the remaining material bridge in the cross-sectional area of the groove 16.
  • FIG. 11 is modified compared to that according to FIG. 10, in that there are further target bending lines x'-x 'extending adjacent to the longitudinal center axis yy crossing the diametrical target bending line xx parallel to it, which now continuous groove 14 runs in the middle of each ceiling half.
  • the peripheral area-like surface area of the plastic cover first lifts off, followed by armor-chain-like material that is connected to the ring collar 13 Section etc.
  • the groove can also cut through the pot wall here.
  • the exemplary embodiment according to FIGS. 12 to 15 is designed with respect to the underside grooving of the plastic cover 9 in the same way as the previous examples, in particular that according to FIG. 8.
  • the reference numbers are therefore used analogously, without repeated text.
  • the difference is that outside the collar portion 13 engaging under the edge of the central recess 8 'in the ceiling 11 of the crimp cap 7 there is a circumferential tear line z.
  • the latter runs concentrically to the edge of the central recess 8.
  • the annular central ceiling section 11 'fastened via the annular collar 13 of the plastic cover 9' separates from the ceiling 11 of the crimp cap 7. It is cleanly separated. In this way, there remains even a somewhat larger central recess 8 in the ceiling 11 for inserting the injection needle.
  • the tear line z consists of an annular notch-like groove.
  • the channel bottom ends under load of a fraction of the initial thickness of the ceiling 11 in front of the underside of the ceiling.
  • the corresponding channel embossing can also be taken into account when deep-drawing the aluminum crimp cap 7.
  • the ring-shaped ceiling section defined by it rises slightly towards the center.
  • the top of the plastic cover 9 also takes a corresponding course.
  • the groove 14 also extends there into the pot wall 9 '. Radially inward, however, the groove 14 ends at the level of the outward facing end 13 ⁇ of the collar portion 13 '. In this plane, a lateral thickening of the ring collar 13 extends in vertical alignment. The parallel outer ring surface thereof is designated by 13 13. The one from the inner Ab cut of the ceiling formed edge of the central recess 8 experiences a stable border, even with sealing on three sides.

Abstract

A closure cap for infusion and transfusion bottles having a rim cap which grips around a rim neck of a bottle and has a cutout which is closed by a plastic lid so that an annular zone of the plastic lid grips below the edge of the cutout to obtain a tightly sealed attachment of the lid this attachment can nevertheless be lifted off with relatively little force due to a radially extending intended-bend line of the plastic lid formed by a thinning of the material.

Description

Die Erfindung bezieht sich auf eine Verschlußkappe für Infu­sions- und Transfusionsflaschen, mit einer einen Bördelhals der Flasche umgreifenden Bördelkappe, welche eine Mittelaus­nehmung besitzt, die vom Mittelbereich eines Kunststoff-­Deckels verschlossen ist derart, daß eine Ringzone des Kunst­stoff-Deckels den Rand der Mittelausnehmung untergreift.The invention relates to a closure cap for infusion and transfusion bottles, with a flanged cap encircling a flanged neck of the bottle, which has a central recess which is closed by the central region of a plastic cover in such a way that an annular zone of the plastic cover engages under the edge of the central recess .

Eine Verschlußkappe dieser Art ist durch die DE-PS 20 40 937 bekannt. Durch Abziehen des Kunststoff-Deckels liegt die Mittelausnehmung frei für das Einführen einer Injektionsna­del, eines Transfusionsbestecks oder dergleichen durch einen im Bördelhals eingelagerten, scheibenartigen Verschlußstop­fen hindurch. Aus Gründen der unverzichtbaren Sterilität des Übergangsbereichs zwischen Kunststoff-Deckel und Bördel­kappe muß einerseits eine wirksame Keimsperre vorliegen, was dort durch eine ringnutartige Dichtungsfuge gegeben ist. Der formpassende Umgriff der Mittelausnehmung durch den zäh-elastischen Kunststoff des Deckels erfordert anderer­seits aber relativ hohe Öffnungskräfte, weshalb dem Kunst­stoff-Deckel oberseitig eine etwa der Flächengröße der Mit­telausnehmung angepaßte Zuglasche angeformt ist. Letztere greift dezentral an und überragt freifliegend den besagten Mittelbereich in enger paralleler Nachbarschaftslage zur Deckeloberseite. Das bedingt aber komplizierte formtechni­sche Maßnahmen. Um die Zuglasche in die greifgerechte Posi­tion zu bringen, muß sie praktisch im Winkel von etwa 90° abgeknickt werden. Hierin besteht eine nicht unerhebliche Gefahr des Abrisses; ohne eine solche Zuglasche ist das Entfernen des Kunststoff-Deckels im Grunde nur noch durch Einsatz von Hilfswerkzeugen möglich. Das aber kann zu Be­schädigungen am Flaschenhals führen.A closure cap of this type is known from DE-PS 20 40 937. By pulling off the plastic cover, the central recess is exposed for the insertion of an injection needle, a transfusion set or the like through a disc-like sealing plug embedded in the flared neck. For reasons of the indispensable sterility of the transition area between the plastic lid and the crimp cap, an effective germ barrier must be present, which is provided by an annular groove-like sealing joint. The form-fitting encirclement of the central recess by the tough-elastic plastic of the cover, on the other hand, requires relatively high opening forces, which is why a pull tab that is approximately matched to the area size of the central recess is molded onto the plastic cover. The latter attacks in a decentralized manner and overhangs the exposed central area in a close parallel position to the top of the lid. However, this requires complicated technical measures. In order to bring the pull tab into the position within easy reach, it has to be practically at an angle of about 90 ° be kinked. This is a not insignificant risk of demolition; Without such a pull tab, the removal of the plastic cover is basically only possible by using auxiliary tools. But this can lead to damage to the bottle neck.

Aufgabe der Erfindung ist es, eine gattungsgemäße Verschluß­kappe in herstellungstechnisch einfacher, gebrauchszuverläs­sigerer Weise ohne Einbuße an Dichtigkeit so auszubilden, daß sich die Verschlußkappe trotz festerer Verbindung mit der Bördelkappe leichter entfernen läßt.The object of the invention is to provide a generic cap in a technically simple, more reliable manner without sacrificing tightness so that the cap can be removed more easily despite a stronger connection to the crimp cap.

Gelöst ist diese Aufgabe durch die im Anspruch 1 angegebene Erfindung.This object is achieved by the invention specified in claim 1.

Die Unteransprüche sind vorteilhafte Weiterbildungen der erfindungsgemäßen Verschlußkappe.The subclaims are advantageous developments of the closure cap according to the invention.

Zufolge solcher Ausgestaltung ist eine gattungsgemäße Ver­schlußkappe geschaffen, die dem Grunderfordernis der keim­freien Abdichtung Rechnung trägt, trotzdem aber durch das Bedienungspersonal unter Einsatz geringerer Kräfte geöffnet werden kann. Erreicht ist dies einfach durch mindestens eine durch Materialverdünnung gebildete, radial verlaufende Soll-Knicklinie des Kunststoffdeckels. Unter Erfassung des Randes des Kunststoff-Deckels wird dieser einfach, definiert durch die besagte Soll-Knicklinie, um diese partiell hochge­klappt. Da sie den Mittelbereich schneidet, kommt es dabei zu einem hälftigen Aushebeln der den Rand der Mittelaus­nehmung dichtend umfassenden Ringzone der dortigen Verbin­dungsstelle sowie zu einem leichten Herausziehen des Re­stes. Je nach Farbgebung des verwendeten Kunststoffmateria­les für den Deckel läßt sich hierbei sogar der entstehende sogenannte "Weißbruch" für eine Sichtkontrolle nutzen, näm­lich dahingehend, ob die Infusionsflasche bereits in Ge­brauch ist bzw. war oder nicht. Eine solche Originalitäts­verschlußanzeige erhöht im medizinischen Einsatzbereich ohne Zweifel die Sicherheit. Um nicht auf einen bestimmten An­griffsbereich angewiesen zu sein, kann die beschriebene Öffnungshilfe mehrfach an der Verschlußkappe realisiert sein, und zwar bspw. durch mehrere in gleichmäßiger Winkel­verteilung vorgesehene, vom Rand des Kunststoff-Deckels bis zum Mittelbereich reichende Soll-Knicklinien. Hierdurch ergeben sich mehrere Hauptbereiche für das Einleiten des hebelgünstigen Hochklappens des Kunststoff-Deckels mit an­schließendem Herausziehen des ringzonenseitigen Rest-Dich­tungsabschnitts. Um die Angriffsbereiche optisch deutlich zu machen und im übrigen auch eine vergrößerte Angriffsflä­che zu bekommen, wird weiter vorgeschlagen, daß der Kunst­stoffdeckel mindestens eine über den Bördelrand der Bördel­kappe auskragende Grifflasche aufweist. Aus formtechnisch vorteilhaften Gründen kann diese Grifflasche auf Höhe der Bodenfläche des topfförmig gestalteten Kunststoff-Deckels sitzen. Zudem besteht auch noch eine vorteilhafte Ausgestal­tung dahingehend, daß der diametral verlaufenden Soll-Knick­linie entsprechende Knicklinien parallel verlaufend benach­bart sind. Weiter besteht eine vorteilhafte Variante darin, daß die Nut sich auch durch die Ringzone, den von ihr um­schriebenen Bereich und die Wandung des Kunststoff-Deckels erstreckt. Das Knicken wird dadurch zusätzlich erleichtert. Schließlich bringt die Erfindung noch eine Ausführungsform dahingehend, daß sich außerhalb des von der Ringzone unter­griffenen Randes der Mittelausnehmung in der Decke der Bör­delkappe eine umlaufende Reißlinie befindet. Unter Abhebeln des Kunststoff-Deckels wird durch diese Ausgestaltung ein­fach der Befestigungsbereich der zweckmäßig aus Aluminium bestehenden Bördelkappe mitherausgehoben. Um möglichst gleiche Trennbedingungen von praktisch allen Seiten her sicherzustellen, erweist es sich noch als vorteilhaft, daß die Reißlinie konzentrisch zum Rand der Mittelausnehmung verläuft. Die Reißlinie läßt sich im Wege des Tiefziehens der Bördelkappe gleich mitberücksichtigen. Im allgemeinen genügt eine kerbtalartige Ringrinne.As a result of such an embodiment, a generic closure cap is created which takes into account the basic requirement of the aseptic seal, but can nevertheless be opened by the operating personnel using lower forces. This is easily achieved by at least one radially extending predetermined crease line of the plastic cover formed by thinning the material. When the edge of the plastic lid is grasped, it is simply folded up around it, defined by the said crease line. Since it intersects the central area, half of the ring zone of the connecting point sealingly surrounding the edge of the central recess is levered out, and the rest is slightly pulled out. Depending on the color of the plastic material used for the lid, the resulting so-called "whitening" can even be used for a visual inspection, namely as to whether the infusion bottle is already in use or was not. Such a tamper-evident display increases in the medical field without Doubt the security. In order not to be dependent on a specific area of attack, the opening aid described can be implemented several times on the closure cap, for example by means of a plurality of predetermined bend lines which are provided in a uniform angular distribution and extend from the edge of the plastic cover to the central area. This results in several main areas for the initiation of the lever-favorable folding up of the plastic cover with subsequent pulling out of the ring seal-side remaining sealing section. In order to make the areas of attack optically clear and also to obtain an enlarged area of attack, it is further proposed that the plastic cover has at least one grip tab projecting over the edge of the flange of the flange. For technical reasons, this grip tab can sit at the level of the bottom surface of the cup-shaped plastic lid. In addition, there is also an advantageous embodiment in such a way that corresponding diametrically extending set buckling lines are adjacent and parallel to each other. Another advantageous variant is that the groove also extends through the ring zone, the area defined by it and the wall of the plastic cover. This also makes kinking easier. Finally, the invention also provides an embodiment in such a way that a circumferential tear line is located outside the edge of the central recess, which is gripped by the ring zone, in the ceiling of the crimp cap. By levering off the plastic cover, the fastening area of the crimp cap, which is expediently made of aluminum, is simply lifted out by this configuration. In order to ensure the same possible separation conditions from practically all sides, it has also proven to be advantageous for the tear line to be concentric with the edge of the central recess. The tear line can be taken into account by deep drawing the crimp cap. In general, a notch-like ring gutter is sufficient.

Der Gegenstand der Erfindung ist nachstehend anhand mehrerer zeichnerisch veranschaulichter Ausführungsbeispiele er­läutert. Es zeigt

  • Fig. 1 eine mit der erfindungsgemäßen Verschlußkappe erster Ausführungsform bestückte Infusionsflasche in Seitenansicht, gemäß dem ersten Ausführungsbei­spiel,
  • Fig. 2 die Draufsicht hierzu,
  • Fig. 3 die Infusionsflasche in Unteransicht,
  • Fig. 4 zur Verdeutlichung der kappenbildenden Einzelteile eine Explosionsdarstellung der Fig. 1,
  • Fig. 5 einen Vertikalschnitt durch den kappenbestückten Bördelhals der Infusionsflasche, und zwar in gegen­über Fig. 1 erheblich vergrößerter Wiedergabe,
  • Fig. 6 den Kunststoff-Deckel in isolierter Darstellung, und zwar in Unteransicht,
  • Fig. 7 den Schnitt gemäß Fig. VII-VII in Fig. 6,
  • Fig. 8 den Kunststoff-Deckel gemäß dem zweiten Ausfüh­rungsbeispiel,
  • Fig. 9 diesen Kunststoff-Deckel in mit der Bördelkappe verbundenem Zustand, nach Schnittverlauf IX-IX in Fig. 8,
  • Fig. 10 die Unteransicht gegen eine andere Variante des Kunststoff-Deckels,
  • Fig. 11 die entsprechende Unteransicht einer dritten Aus­führungsform des Kunststoff-Deckels,
  • Fig. 12 die Unteransicht einer Verschlußkappe gemäß dem vierten Ausführungsbeispiel,
  • Fig. 13 einen Vertikalschnitt durch den kappenbestückten Bördelhals der Infusionsflasche,
  • Fig. 14 die gleiche Figur bei abgezogenem Kunststoffdeckel unter Verdeutlichung der an dem Kunststoff-Deckel verbliebenen herausgerissenen inneren Randpartie der Bördelkappe und
  • Fig. 15 eine Herausvergrößerung aus Fig. 13.
The subject matter of the invention is explained below on the basis of a number of illustrative exemplary embodiments. It shows
  • 1 is a side view of an infusion bottle equipped with the closure cap of the first embodiment according to the invention, according to the first embodiment,
  • 2 is a top view of this,
  • 3 the infusion bottle in bottom view,
  • 4 shows an exploded view of FIG. 1 to illustrate the cap-forming individual parts,
  • 5 shows a vertical section through the cap-fitted flange neck of the infusion bottle, namely in a considerably enlarged representation compared to FIG. 1,
  • 6 the plastic lid in an isolated representation, namely in a bottom view,
  • 7 shows the section according to FIGS. VII-VII in FIG. 6,
  • 8 the plastic cover according to the second embodiment,
  • 9 this plastic cover in the state connected to the crimp cap, according to section line IX-IX in FIG. 8,
  • 10 is the bottom view against another variant of the plastic cover,
  • 11 is the corresponding bottom view of a third embodiment of the plastic cover,
  • 12 is the bottom view of a closure cap according to the fourth embodiment,
  • 13 shows a vertical section through the cap-fitted flared neck of the infusion bottle,
  • Fig. 14 shows the same figure with the plastic cover removed, illustrating the torn-off inner edge portion of the crimp cap remaining on the plastic cover and
  • 15 shows an enlargement from FIG. 13.

Die eine Infusions- oder Transfusionsflüssigkeit 1 enthalten­de Flasche 2 geht über einen sich kegelstumpfförmig verjün­genden Abschnitt in den sogenannten Bördelhals 3 über. Letztere bildet durch entsprechenden Wandungsversatz eine innere Ringschulter 4 zur randseitigen Auflage eines scheib­chenförmigen Verschlußstopfens 5. Der besteht aus Gummi, Kunststoff oder sontigem von einer Kanüle durchdringbarem und sich wieder schließenden Material.The bottle 2 containing an infusion or transfusion liquid 1 merges into a so-called flared neck 3 via a section which tapers in the shape of a truncated cone. The corresponding wall offset forms an inner annular shoulder 4 for supporting a disk-shaped sealing plug 5 on the edge. This is made of rubber, plastic or other material that can be penetrated by a cannula and closes again.

Der relativ dickwandige Verschlußstopfen 5 schließt mit der Stirnfläche 3′ des Bördelhalses 3 im wesentlichen ebenen­gleich ab.The relatively thick-walled plug 5 closes with the end face 3 'of the flared neck 3 from substantially the same level.

Den keimhemmenden Abschluß bildet eine darauf aufliegende Verschlußkappe 6. Letztere besteht aus einer topfförmigen Bördelkappe 7 mit zentraler Mittelausnehmung 8, welche von einem Kunststoff-Deckel 9 verschlossen ist.The germ-inhibiting closure is formed by a sealing cap 6 resting thereon. The latter consists of a pot-shaped crimping cap 7 with a central central recess 8, which is closed by a plastic cover 9.

Die Bördelkappe 7 weist eine zylindrische Topfwandung auf, deren Rand eine ringförmige Schulter 10 des Bördelhalses 3 untergreift. Die Bördelkappe 7 besteht aus relativ dünnwand­igem Aluminium. Der schulteruntergreifende Bördelrand ist mit 7′ bezeichnet.The crimp cap 7 has a cylindrical pot wall, the edge of which engages under an annular shoulder 10 of the crimp neck 3. The crimp cap 7 is made of relatively thin-walled aluminum. The shoulder-flanging edge is designated 7 '.

Der die Decke 11 der topfförmigen Bördelkappe 7 bildende Boden der Kappe ist ebenflächig. Der Rand der darin angeord­neten Mittelausnehmung 8 geht in eine inverse Bördelung über, so daß dieser Rand quergerundet ist und auf einem kur­zen radialen Abschnitt praktisch doppelwandig ausgebildet ist. Der dabei entstandene Ringkragen trägt das Bezugszei­chen 12. Er liegt mit seiner Innenseite an der Unterseite der Decke 11 an.The bottom of the cap forming the ceiling 11 of the cup-shaped crimp cap 7 is flat. The edge of the central recess 8 arranged therein merges into an inverse flare, so that this edge is transversely rounded and is practically double-walled on a short radial section. The ring collar created in this way bears the reference number 12. Its inside lies against the underside of the cover 11.

Die Verbindung zwischen Bördelkappe 7 und dem ebenfalls topfförmig gestalteten Kunststoff-Deckel 9 kann durch thermi­sches Annieten oder aber auch gleich durch Anspritzen erfol­gen. Im Falle des thermischen Annietens bildet der Kunst­stoff-Deckel 9 zentralliegend einen in Richtung der Flasche weisenden Stehkragen 13 aus, dessen Außendurchmesser dem lichten Durchmesser der kreisrunden Mittelausnehmung 8 ent­spricht. Der zylindrisch gestaltete Stehkragen 13 durch­greift bei Zuordnung die besagte Mittelausnehmung 8, wonach der überstehende Kragenabschnitt 13′ nach auswärts gerichtet umgelegt wird. Der diesbezügliche Verbindungsbereich er­weist sich als dicht und somit als wirksame Keimsperre. Im Grunde liegt dort der Rand der Mittelausnehmung 8 dann in einer Ringnut ein.The connection between the crimp cap 7 and the likewise cup-shaped plastic cover 9 can be made by thermal riveting or by spraying. In the case of thermal riveting, the plastic lid 9 forms a standing collar 13 pointing in the direction of the bottle, the outer diameter of which corresponds to the inside diameter of the circular central recess 8. The cylindrically shaped stand-up collar 13 passes through said center recess 8 when assigned, after which the projecting collar portion 13 'is turned outwards. The related connection area proves to be tight and thus an effective germ barrier. Basically, the edge of the central recess 8 then lies in an annular groove.

Die Mantelwand der Bördelkappe 7 wird nur partiell von der zylindrischen Wandung 9′ des Kunststoff-Deckels 9 eng anlie­gend übergriffen, und zwar etwa auf einem Drittel der axia­len Länge. Die Topfwandung 9′ des Kunststoff-Deckels 9 ist um ein Vielfaches dickwandiger als die der Bördelkappe 7. Gleiches gilt im Grunde für die Dicke der Decke 9˝ des Kunststoff-Deckels 9.The outer wall of the crimp cap 7 is only partially overlapped by the cylindrical wall 9 'of the plastic cover 9, approximately over a third of the axial length. The pot wall 9 'of the plastic cover 9 is many times thicker than that of the crimp cap 7. The same basically applies to the thickness of the ceiling 9' of the plastic cover 9.

Zur Ingebrauchnahme zwecks Entnahme der Infusionsflüssigkeit 1 braucht nur der Kunststoff-Deckel 9 entfernt zu werden. Dies bedeutet Aufhebung der Verbindung zwischen diesem und der Bördelkappe 7, die mit ihrer Ringfläche den Verschluß­stopfen 5 im Randbereich überfängt (der in Fig. 5 und 9 dargestellte spaltartige Abstand ist aus Gründen der Deut­lichkeit stark übertrieben). Erleichtert ist das entspre­chende Lösen der Kunststoff-Kappe 9 durch mindestens eine durch Materialverdünnung gebildete, radialverlaufende Soll-­Knicklinie x-x des Kunststoff-Deckels 9. Gebildet sind die Soll-Knicklinien x-x von einer Nut 14. Diese befindet sich an der Unterseite 15 des Kunststoff-Deckels 9. Die Nuten 14 beginnen auf Höhe der Mantelwand des zentralliegenden Ring­kragens 13 und erstrecken sich, in Verlängerung gesehen, diametral verlaufend, also die Längsmittelachse y-y der rotationssymmetrisch gestalteten Flasche 2 schneidend, bis hin zur zylindrischen Innenfläche der Topfwandung 9′. Die Nut kann auch deckeloberseitig liegen.In order to use the infusion liquid 1, only the plastic cover 9 needs to be removed. This means removal of the connection between the latter and the crimp cap 7, which, with its annular surface, overlaps the sealing plug 5 in the edge region (that in FIGS. 5 and 9 shown gap-like distance is greatly exaggerated for reasons of clarity). The corresponding loosening of the plastic cap 9 is facilitated by at least one radially extending nominal crease line xx of the plastic cover 9 formed by material thinning. The nominal crease lines xx are formed by a groove 14. This is located on the underside 15 of the plastic Lid 9. The grooves 14 begin at the level of the jacket wall of the central ring collar 13 and extend, seen in extension, diametrically extending, so cutting the longitudinal center axis yy of the rotationally symmetrical bottle 2, up to the cylindrical inner surface of the pot wall 9 '. The groove can also be on the top of the cover.

Die Tiefe der Nut entspricht etwa 4/5 der Dicke der Decke 9˝ des Kunststoff-Deckels 9. Die Breite der Nut 14 ent­spricht der Tiefe (vergl. Fig. 7). Bei der aus Fig. 6 er­sichtlichen winkelgleichen Anordnung von insgesamt vier Nuten 14, von denen jeweils zwei in linearer Ausrichtung und dabei die Längsmittelachse y-y schneidend verlaufen, ergeben sich beim Hochwinkeln jeweils Falthälften. Es liegt ein günstiger langer Hebelarm zugrunde, welcher den den Befesti­gungsabschnitt bildenden Ringkragen 13 hälftig exakt de­finiert aushebt. Der restliche Aushub fällt entsprechend ohne größeren Krafteinsatz aus. Diese Hälfte kann man prak­tisch nutparallel herausziehen.The depth of the groove corresponds to approximately 4/5 of the thickness of the ceiling 9˝ of the plastic cover 9. The width of the groove 14 corresponds to the depth (see FIG. 7). In the arrangement of the same angle shown in FIG. 6 of a total of four grooves 14, two of which each run in a linear orientation and intersect the longitudinal central axis y-y, fold halves are produced when the angles are raised. It is based on an inexpensive long lever arm, which lifts the ring collar 13 forming the fastening section exactly in half. The rest of the excavation works accordingly without any great effort. This half can be pulled out practically parallel to the groove.

Bei Kunststoff-Deckeln oberseitiger Nutung lassen sich die Angriffsbereiche optisch erkennen. Ist die Nutung jedoch, wie beim Ausführungsbeispiel beschrieben, an der Unterseite des besagten Deckels vorgenommen, so erweist es sich als bedienungsgünstig, daß der Kunststoff-Deckel 9 mindestens ein über den Bördelrand 7′ der Bördelkappe 7 horizontal auskragende Grifflasche 16 aufweist (so braucht die recht schmale Deckelrandkante nicht gefaßt zu werden). Es handelt sich um mützenschirmartige, auf Höhe der Decke 9˝ verlaufen­de Anformungen, welche zudem zu einer noch größeren Hebelarm­ länge führen. Die Grifflaschen 16 kragen jeweils senkrecht zur diametralen Soll-Knicklinie x-x aus. Ihre freien Enden sind parallelverlaufend zur besagten Linie gekappt. Ihre Seitenflanken 16′ laufen als konvexe Bogenabschnitte tangie­rend in die Mantelfläche der Topfwandung 9′ ein. Bei der in Fig. 6 und 8 angewandten Viererverteilung der Nuten 16 wei­sen die Grifflaschen 16 einen im wesentlichen trapezförmigen Grundriß auf. Die größere Basisfläche wurzelt in der Mantel­wandung und nimmt einen entsprechend gekrümmten Verlauf. Grundrißmäßig handelt es sich praktisch um einen Kreis im Quadrat. Die dortigen Seitenflanken 16′ der Grifflaschen 16 stehen also im rechten Winkel zueinander.With plastic covers with groove on the top, the areas of attack can be visually recognized. If, however, as described in the exemplary embodiment, the groove is made on the underside of the said lid, it proves to be easy to use that the plastic lid 9 has at least one grip tab 16 which projects horizontally over the flanged edge 7 'of the flared cap 7 (so it needs the quite narrow edge of the lid not to be caught). It is a cap-like, at the ceiling 9˝ extending formations, which also leads to an even larger lever arm lead length. The grip tabs 16 each protrude perpendicular to the diametrical nominal crease line xx. Their free ends are cut parallel to the line in question. Your side flanks 16 'run as a convex arc sections tangent into the outer surface of the pot wall 9'. In the four-way distribution of the grooves 16 used in FIGS. 6 and 8, the grip tabs 16 have an essentially trapezoidal outline. The larger base area is rooted in the jacket wall and takes a correspondingly curved course. The floor plan is practically a circle in a square. The side flanks 16 'there of the handle straps 16 are therefore at right angles to one another.

Um auch den vom Ringkragen 13 umschriebenen Bereich und den Ringkragen selber biegefreudiger zu gestalten, können die Nuten 14 alternativ in der umschriebenen Innenfläche rich­tungsgleich fortgeführt sein und dabei auch noch die Topfwan­dung 9′ des Kunststoff-Deckels 9 miterfassen (vergl. Fig. 6, strichpunktierte Eintragung). Die entsprechende Nutung durchtrennt bis in den jeweiligen Topfrand. Andererseits besteht aber auch die Möglichkeit, den Rücken dieser Fläche insgesamt materialverdünnend auszunehmen, wie dies aus Fig. 9 ersichtlich ist. Die entsprechende oberseitige Aus­nehmung trägt das Bezugszeichen 17. Sie kann auch unten liegen. Der Reststeg entspricht der Dicke der verbleibenden Materialbrücke im Querschnittsbereich der Nut 16.In order to make the area circumscribed by the ring collar 13 and the ring collar itself more flexible, the grooves 14 can alternatively be continued in the circumscribed inner surface in the same direction and also include the pot wall 9 'of the plastic cover 9 (see FIG. 6, dot-dash lines) Registration). The corresponding groove cuts through to the respective rim of the pot. On the other hand, there is also the possibility of taking out the back of this surface as a material, as can be seen in FIG. 9. The corresponding top recess has the reference number 17. It can also be located below. The remaining web corresponds to the thickness of the remaining material bridge in the cross-sectional area of the groove 16.

Das Ausführungsbeispiel gemäß Fig. 11 ist insofern gegenüber dem gemäß Fig. 10 abgewandelt, als sich dort noch benachbart zur die Längsmittelachse y-y kreuzenden Ausrichtung der diametralen Soll-Knicklinie x-x parallel zu dieser verlau­fend weitere Soll-Knicklinien x′-x′ erstrecken, deren nun durchgehende Nut 14 mittig der jeweiligen Deckenhälfte ver­läuft. Der periphere kreisabschnittartige Flächenbereich des Kunststoff-Deckels hebt zuerst ab, dann folgt panzerket­tenartig der materialmäßig mit dem Ringkragen 13 verbundene Abschnitt usw. Die Nutung kann auch hier die Topfwandung durchtrennen.The embodiment according to FIG. 11 is modified compared to that according to FIG. 10, in that there are further target bending lines x'-x 'extending adjacent to the longitudinal center axis yy crossing the diametrical target bending line xx parallel to it, which now continuous groove 14 runs in the middle of each ceiling half. The peripheral area-like surface area of the plastic cover first lifts off, followed by armor-chain-like material that is connected to the ring collar 13 Section etc. The groove can also cut through the pot wall here.

Das Ausführungsbeispiel gemäß den Fig. 12 bis 15 ist bezüg­lich der unterseitigen Nutung des Kunststoff-Deckels 9 so ausgebildet wie die voraufgegangenen Beispiele, insbesondere das gemäß Fig. 8. Die Bezugsziffern sind daher, ohne textli­che Wiederholungen, sinngemäß angewandt. Der Unterschied besteht jedoch darin, daß sich außerhalb des die Randpartie der Mittelausnehmung 8 untergreifenden Kragenabschnitts 13′ in der Decke 11 der Bördelkappe 7 eine umlaufende Reißlinie z befindet. Letztere verläuft konzentrisch zum Rand der Mittelausnehmung 8. Unter Abheben des Kunststoff-Deckels 9 trennt sich der über den Ringkragen 13 des Kunststoff-­Deckels 9 befestigte ringförmige, zentrale Deckenabschnitt 11′ von der Decke 11 der Bördelkappe 7. Er wird sauber herausgetrennt. Es verbleibt auf diese Weise sogar noch eine etwas größere Mittelausnehmung 8 in der Decke 11 zum Einführen der Injektionsnadel.The exemplary embodiment according to FIGS. 12 to 15 is designed with respect to the underside grooving of the plastic cover 9 in the same way as the previous examples, in particular that according to FIG. 8. The reference numbers are therefore used analogously, without repeated text. The difference, however, is that outside the collar portion 13 engaging under the edge of the central recess 8 'in the ceiling 11 of the crimp cap 7 there is a circumferential tear line z. The latter runs concentrically to the edge of the central recess 8. When the plastic cover 9 is lifted, the annular central ceiling section 11 'fastened via the annular collar 13 of the plastic cover 9' separates from the ceiling 11 of the crimp cap 7. It is cleanly separated. In this way, there remains even a somewhat larger central recess 8 in the ceiling 11 for inserting the injection needle.

Die Reißlinie z besteht aus einer ringförmigen kerbtalarti­gen Rinne. Der Rinnengrund endet unter Belastung eines Bruchteils der Ausgangsdicke der Decke 11 vor der Unterseite der Decke. Die entsprechende Rinnenprägung kann beim Tief­ziehen der aus Aluminium bestehenden Bördelkappe 7 gleich mitberücksichtigt sein. Der durch sie definierte ringförmi­ge Deckenabschnitt steigt zum Zentrum hin leicht an. Einen entsprechenden Verlauf nimmt auch die Oberseite des Kunst­stoff-Deckels 9.The tear line z consists of an annular notch-like groove. The channel bottom ends under load of a fraction of the initial thickness of the ceiling 11 in front of the underside of the ceiling. The corresponding channel embossing can also be taken into account when deep-drawing the aluminum crimp cap 7. The ring-shaped ceiling section defined by it rises slightly towards the center. The top of the plastic cover 9 also takes a corresponding course.

In Weiterbildung zur Lösung gemäß Fig. 8 erstreckt sich die Nut 14 auch dort in die Topfwandung 9′ hinein. Radial nach innen gerichtet endet die Nut 14 jedoch auf Höhe des aus­wärtsweisenden Stirnendes 13˝ des Kragenabschnitts 13′. In dieser Ebene erstreckt sich vertikal fluchtend eine seitli­che Verdickung des Ringkragens 13. Deren parallele äußere Ringfläche ist mit 13‴ bezeichnet. Der vom inneren Ab­ schnitt der Decke gebildete Rand der Mittelausnehmung 8 erfährt insoweit eine stabile Einfassung, dies sogar bei an drei Seiten erfolgender Abdichtung.In a further development to the solution according to FIG. 8, the groove 14 also extends there into the pot wall 9 '. Radially inward, however, the groove 14 ends at the level of the outward facing end 13˝ of the collar portion 13 '. In this plane, a lateral thickening of the ring collar 13 extends in vertical alignment. The parallel outer ring surface thereof is designated by 13 13. The one from the inner Ab cut of the ceiling formed edge of the central recess 8 experiences a stable border, even with sealing on three sides.

Alle in der Beschreibung erwähnten und in der Zeichnung dargestellten neuen Merkmale sind erfindungswesentlich, auch soweit sie in den Ansprüchen nicht ausdrücklich beansprucht sind.All the new features mentioned in the description and shown in the drawing are essential to the invention, even if they are not expressly claimed in the claims.

Claims (9)

1. Verschlußkappe für Infusions- und Transfusionsflaschen, mit einer einen Bördelhals (3) der Flasche (2) umgreifenden Bördelkappe (7), welche eine Mittelausnehmung (8) besitzt, die vom Mittelbereich eines Kunststoff-Deckels (9) verschlos­sen ist derart, daß eine Ringzone des Kunststoff-Deckels den Rand der Mittelausnehmung (8) untergreift, gekennzeichnet durch mindestens eine durch Materialverdünnung gebildete, radial verlaufende Soll-Knicklinie (x-x) des Kunststoff-­Deckels (9).1. Cap for infusion and transfusion bottles, with a crimp neck (3) of the bottle (2) encompassing crimp cap (7) which has a central recess (8) which is closed by the central region of a plastic lid (9) such that an annular zone of the plastic cover engages under the edge of the central recess (8), characterized by at least one radially extending predetermined crease line (xx) of the plastic cover (9) formed by material thinning. 2. Verschlußkappe nach Anspruch 1, gekennzeichnet durch mehrere in gleichmäßiger Winkelverteilung vorgesehene, vom Rand des Kunststoff-Deckels (9) bis zum Mittelbereich und weiter reichende, diametrale Soll-Knicklinien (x-x).2. Cap according to claim 1, characterized by several provided in a uniform angular distribution, from the edge of the plastic cover (9) to the central region and further reaching, diametrical nominal crease lines (x-x). 3. Verschlußkappe nach einem oder mehreren der vorhergehen­den Ansprüche, dadurch gekennzeichnet, daß die Soll-Knick­linien (x-x) von einer Nut (14) an der Unterseite (15) des Kunststoff-Deckels (9) gebildet ist.3. Cap according to one or more of the preceding claims, characterized in that the predetermined kink lines (x-x) is formed by a groove (14) on the underside (15) of the plastic cover (9). 4. Verschlußkappe nach einem oder mehreren der vorhergehen­den Ansprüche, dadurch gekennzeichnet, daß der Kunststoff-­Deckel (9) mindestens eine über den Bördelrand der Bördelkap­pe (7) auskragende Grifflasche (16) aufweist.4. Cap according to one or more of the preceding claims, characterized in that the plastic cover (9) has at least one grip tab (16) projecting over the flanged edge of the flared cap (7). 5. Verschlußkappe nach einem oder mehreren der vorhergehen­den Ansprüche, dadurch gekennzeichnet, daß die Grifflaschen (16) auf Höhe der Bodenfläche des topfförmig gestalteten Kunststoff-Deckels (17) verlaufen.5. Cap according to one or more of the preceding claims, characterized in that the grip tabs (16) run at the level of the bottom surface of the cup-shaped plastic cover (17). 6. Verschlußkappe nach einem oder mehreren der vorhergehen­den Ansprüche, dadurch gekennzeichnet, daß der diametral verlaufenden Soll-Knicklinie (x-x) parallelverlaufende Soll-­Knicklinien (x′-x′) benachbart sind.6. A closure cap according to one or more of the preceding claims, characterized in that the diametrically extending nominal kink line (xx) parallel nominal kink lines (x'-x ') are adjacent. 7. Verschlußkappe nach einem oder mehreren der vorhergehen­den Ansprüche, dadurch gekennzeichnet, daß die Nut (14) sich auch durch die Ringzone (Ringkragen 13), den von ihr um­schriebenen Bereich und die Wandung (Topfwandung 9′) des Kunststoff-Deckels (9) erstreckt.7. Cap according to one or more of the preceding claims, characterized in that the groove (14) also through the ring zone (ring collar 13), the area circumscribed by it and the wall (pot wall 9 ') of the plastic cover (9) extends. 8. Verschlußkappe nach einem oder mehreren der vorhergehen­den Ansprüche, dadurch gekennzeichnet, daß sich außerhalb des von der Ringzone (Ringkragen 13) untergriffenen Randes der Mittelausnehmung (8) in der Decke (11) der Bördelkappe (7) eine umlaufende Reißlinie (z) befindet.8. Cap according to one or more of the preceding claims, characterized in that there is a circumferential tear line (z) outside of the edge of the central recess (8) in the cover (11) of the crimp cap (7), which is gripped by the ring zone (ring collar 13) . 9. Verschlußkappe nach einem oder mehreren der vorhergehen­den Ansprüche, dadurch gekennzeichnet, daß die Reißlinie (z) konzentrisch zum Rand der Mittelausnehmung (8) verläuft.9. Cap according to one or more of the preceding claims, characterized in that the tear line (z) is concentric with the edge of the central recess (8).
EP88104448A 1987-05-07 1988-03-21 Closure cap for infusion and transfusion bottles Expired - Lifetime EP0291658B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT88104448T ATE64864T1 (en) 1987-05-07 1988-03-21 CAP FOR INFUSIONS AND TRANSFUSIONS BOTTLES.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3715175A DE3715175C1 (en) 1987-05-07 1987-05-07 Cap for infusion and transfusion bottles
DE3715175 1987-05-07

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EP0291658A1 true EP0291658A1 (en) 1988-11-23
EP0291658B1 EP0291658B1 (en) 1991-07-03

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US (1) US4844267A (en)
EP (1) EP0291658B1 (en)
JP (1) JP2563125B2 (en)
AT (1) ATE64864T1 (en)
CA (1) CA1305684C (en)
DE (2) DE3715175C1 (en)
ES (1) ES2023453B3 (en)
GR (1) GR3002258T3 (en)

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EP0540814A1 (en) * 1991-10-04 1993-05-12 Pohl GmbH & Co. KG Closure cap for pharmaceutical container
EP0554393A1 (en) * 1990-10-30 1993-08-11 The West Company, Incorporated Decoration, identification and differentiation closure system
EP0598179A1 (en) * 1992-11-19 1994-05-25 Pohl GmbH & Co. KG Closure for medication bottle
EP0624527A1 (en) * 1993-05-12 1994-11-17 Capsulit S.P.A. A capsule of plastic material particularly for infusion bottles
WO1994026613A1 (en) * 1993-05-06 1994-11-24 Pharma-Gummi Wimmer West Gmbh Bottle cap
WO2001060699A2 (en) * 2000-02-18 2001-08-23 Helvoet Pharma Belgium N.V. Closing cap for infusion and transfusion bottles
DE102010038031A1 (en) 2010-10-07 2012-04-12 Helvoet Pharma Belgium N.V. Producing flange cap useful for container for holding pharmaceutical substance, comprises molding a material strip exhibiting a pre-plastic-coated film layer to flanged cap by punching and deep drawing
WO2013053384A1 (en) 2011-10-11 2013-04-18 Datwyler Pharma Packaging Belgium Nv Method for producing a crimp cap, crimp cap and container
DE102012102881A1 (en) 2012-04-03 2013-10-10 Datwyler Pharma Packaging International Nv Method for producing a crimp cap, crimp cap and container with crimp cap
US9402782B2 (en) 2011-12-15 2016-08-02 Ge Healthcare As Package with tamper-evident features
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FR2986782B1 (en) * 2012-02-13 2014-03-07 Raymond A & Cie PLUG LOCKING DEVICE ON FLANGE CONTAINER, PLUG-IN CLOSURE FLANGE CONTAINER PROVIDED WITH SUCH LATCHING DEVICE
CN105775372B (en) * 2016-05-10 2017-12-01 苏州创扬医药科技股份有限公司 A kind of combination cover for being used to freeze bottle
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EP0554393A1 (en) * 1990-10-30 1993-08-11 The West Company, Incorporated Decoration, identification and differentiation closure system
EP0554393A4 (en) * 1990-10-30 1994-03-18 West Co Decoration, identification and differentiation closure system.
EP0540814A1 (en) * 1991-10-04 1993-05-12 Pohl GmbH & Co. KG Closure cap for pharmaceutical container
EP0598179A1 (en) * 1992-11-19 1994-05-25 Pohl GmbH & Co. KG Closure for medication bottle
WO1994026613A1 (en) * 1993-05-06 1994-11-24 Pharma-Gummi Wimmer West Gmbh Bottle cap
US5678718A (en) * 1993-05-06 1997-10-21 The West Company Deutschland Gmbh Bottle cap
EP0624527A1 (en) * 1993-05-12 1994-11-17 Capsulit S.P.A. A capsule of plastic material particularly for infusion bottles
WO2001060699A3 (en) * 2000-02-18 2002-04-25 Helvoet Pharma Closing cap for infusion and transfusion bottles
WO2001060699A2 (en) * 2000-02-18 2001-08-23 Helvoet Pharma Belgium N.V. Closing cap for infusion and transfusion bottles
US6868978B2 (en) 2000-02-18 2005-03-22 Helvoet Pharma Belgium N.V. Closing cap for infusion and transfusion bottles
DE102010038031A1 (en) 2010-10-07 2012-04-12 Helvoet Pharma Belgium N.V. Producing flange cap useful for container for holding pharmaceutical substance, comprises molding a material strip exhibiting a pre-plastic-coated film layer to flanged cap by punching and deep drawing
DE102010038031B4 (en) * 2010-10-07 2017-01-26 Helvoet Pharma Belgium N.V. Method for producing a crimp cap, crimp cap and container
US9815601B2 (en) 2011-09-29 2017-11-14 Ge Healthcare As Package
WO2013053384A1 (en) 2011-10-11 2013-04-18 Datwyler Pharma Packaging Belgium Nv Method for producing a crimp cap, crimp cap and container
US9585811B2 (en) 2011-10-11 2017-03-07 Datwyler Pharma Packaging Belgium Nv Method for producing a crimp cap, crimp cap and container
US9402782B2 (en) 2011-12-15 2016-08-02 Ge Healthcare As Package with tamper-evident features
DE102012102881A1 (en) 2012-04-03 2013-10-10 Datwyler Pharma Packaging International Nv Method for producing a crimp cap, crimp cap and container with crimp cap
WO2013149844A1 (en) 2012-04-03 2013-10-10 Datwyler Pharma Packaging International Nv Method for producing a flanged cap, flanged cap, and vessel with flange cap

Also Published As

Publication number Publication date
ES2023453B3 (en) 1992-01-16
GR3002258T3 (en) 1992-12-30
JP2563125B2 (en) 1996-12-11
DE3715175C1 (en) 1988-11-24
JPS63281652A (en) 1988-11-18
DE3863484D1 (en) 1991-08-08
CA1305684C (en) 1992-07-28
ATE64864T1 (en) 1991-07-15
US4844267A (en) 1989-07-04
EP0291658B1 (en) 1991-07-03

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