EP0209543A4 - Peptide fragments of human apolipoprotein, type-specific antibodies and methods of use. - Google Patents

Peptide fragments of human apolipoprotein, type-specific antibodies and methods of use.

Info

Publication number
EP0209543A4
EP0209543A4 EP19860900570 EP86900570A EP0209543A4 EP 0209543 A4 EP0209543 A4 EP 0209543A4 EP 19860900570 EP19860900570 EP 19860900570 EP 86900570 A EP86900570 A EP 86900570A EP 0209543 A4 EP0209543 A4 EP 0209543A4
Authority
EP
European Patent Office
Prior art keywords
methods
type
specific antibodies
peptide fragments
human apolipoprotein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19860900570
Other languages
German (de)
French (fr)
Other versions
EP0209543A1 (en
Inventor
George Fareed
Arup Sen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
International Genetic Engineering Inc
Original Assignee
International Genetic Engineering Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by International Genetic Engineering Inc filed Critical International Genetic Engineering Inc
Publication of EP0209543A1 publication Critical patent/EP0209543A1/en
Publication of EP0209543A4 publication Critical patent/EP0209543A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775—Apolipopeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
EP19860900570 1984-12-31 1985-12-26 Peptide fragments of human apolipoprotein, type-specific antibodies and methods of use. Withdrawn EP0209543A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68804084A 1984-12-31 1984-12-31
US688040 1984-12-31

Publications (2)

Publication Number Publication Date
EP0209543A1 EP0209543A1 (en) 1987-01-28
EP0209543A4 true EP0209543A4 (en) 1989-07-11

Family

ID=24762872

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19860900570 Withdrawn EP0209543A4 (en) 1984-12-31 1985-12-26 Peptide fragments of human apolipoprotein, type-specific antibodies and methods of use.

Country Status (3)

Country Link
EP (1) EP0209543A4 (en)
JP (1) JPS62501770A (en)
WO (1) WO1986004144A1 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2070820T3 (en) * 1986-08-06 1995-06-16 Scripps Clinic Res MONOCLONAL ANTIBODIES SPECIFIC TO APOLIPOPROTEIN B, PRODUCED BY TWO NEW HYBRIDOMES.
US4828986A (en) * 1986-09-29 1989-05-09 Scripps Clinic And Research Foundation Assay method and diagnostic system for determining the ratio of APO B-100 to APO A-I in a blood sample
US5126240A (en) * 1986-09-29 1992-06-30 Curtiss Linda K Hybridomas and monoclonal paratopic molecules to apolipoprotein a-i
DE3636851A1 (en) * 1986-10-29 1988-05-11 Boehringer Mannheim Gmbh METHOD AND REAGENT FOR SPECIFIC DETERMINATION OF THE CHOLESTERIN OF THE HDL FACTION
FR2612298B1 (en) * 1987-03-10 1989-06-30 Sebia Laboratoires NOVEL METHOD FOR THE SIMULTANEOUS ASSAY OF AT LEAST TWO SUB-ASSEMBLIES OF APOLIPOPROTEINS CONTAINED IN A BIOLOGICAL MEDIUM
GB8717791D0 (en) * 1987-07-28 1987-09-03 Baralle F E Immunoassay method
US5055396A (en) * 1987-11-03 1991-10-08 Scripps Clinic And Research Foundation Diagnostic methods and systems for quantifying apo ai
KR900700884A (en) * 1988-03-29 1990-08-17 레이먼드 에이치. 칸 Diagnostic Methods and Diagnostic Systems for Quantifying Apo AI
AU663291B2 (en) * 1990-05-03 1995-10-05 New England Deaconess Hospital Corporation Synthetic peptides for arterial imaging
WO1994004563A1 (en) * 1992-08-14 1994-03-03 Shino-Test Corporation PEPTIDES CONTAINING RESPECTIVE AMINO ACID SEQUENCES SELECTED FROM AMONG THOSE OF LIPOPROTEIN(a) AND APOLIPOPROTEIN(a), ANTIBODIES RESPECTIVELY RECOGNIZING THESE AMINO ACID SEQUENCES, AND METHOD OF ASSAYING WITH THESE ANTIBODIES
EP0614912B1 (en) * 1993-02-09 2000-05-17 Roche Diagnostics GmbH Lipoprotein (a)-peptides and use thereof
JPH06279494A (en) * 1993-02-09 1994-10-04 Boehringer Mannheim Gmbh Lipoprotein (a) peptide and its use
GB0121171D0 (en) * 2001-08-31 2001-10-24 Glaxosmithkline Biolog Sa Vaccine
US7314762B2 (en) 2001-11-21 2008-01-01 Nanogen, Inc. Apolipoprotein biopolymer markers indicative of insulin resistance
US7125678B2 (en) 2001-11-23 2006-10-24 Nanogen, Inc. Protein biopolymer markers predictive of type II diabetes
DE102004040735B4 (en) 2004-08-23 2006-11-23 ETH-Zürich, Institut für Lebensmittelwissenschaft, Laboratorium für Lebensmittelverfahrenstechnik Process for the mechanically gentle production of finely dispersed micro / nano-emulsions with narrow droplet size distribution and apparatus for carrying out the process
RU2017126088A (en) 2011-02-07 2019-01-31 Серени Терапеутикс Холдинг С.А. Lipoprotein complexes and their preparation and use

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0044170A1 (en) * 1980-07-11 1982-01-20 Beecham Group Plc Beta-lactam antibiotics, their preparation and use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4554101A (en) * 1981-01-09 1985-11-19 New York Blood Center, Inc. Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
US4478744A (en) * 1982-01-25 1984-10-23 Sherwood Medical Company Method of obtaining antibodies
US4544500A (en) * 1982-04-14 1985-10-01 Scripps Clinic And Research Foundation Synthetic foot and mouth disease antigen
US4521334A (en) * 1982-07-27 1985-06-04 The University Of Tennesse Research Corporation Synthetic polypeptide fragments
US4493795A (en) * 1983-10-17 1985-01-15 Syntex (U.S.A.) Inc. Synthetic peptide sequences useful in biological and pharmaceutical applications and methods of manufacture

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0044170A1 (en) * 1980-07-11 1982-01-20 Beecham Group Plc Beta-lactam antibiotics, their preparation and use

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
Annual Review Biochemistry, Vol. 44, 1975, pages 183-207; J.D. MORRISETT et al.: "Lipoproteins: Structure and function", whole article. *
Biochemical & Biophysical Research Communications, Vol. 80, 1978, pages 623-630; H.B. BREWER et al.: "The amino acid sequence of human APOA-I, an apolipoprotein isolated from high density lipoproteins", whole article. *
Biochemistry, Vol. 16, No. 19, 1977, pages 4150-4156; S.J.T. MAO et al.: "Mechanism of lipid-protein interaction in the plasma lipoproteins: Lipid-binding properties of synthetic fragments of apolipoprotein A-II", Abstract. *
CHEMICAL ABSTRACTS, Vol. 94, 1981, page 108, Ref. No. 11810f; Columbus, Ohio, US, J.P. KUPFERBERG et al.: "Synthetic apolipoprotein model peptides: Structural determinants of peptide-phospholipid interactions", & Pept. Struct. Biol. Funct., Proc. Am. Pept. Symp. 6th, 1979, 519-22, Abstract. *
CHEMICAL ABSTRACTS, Vol. 94, 1981, page 129, Ref. No. 1241g; Columbus, Ohio, US, J.T. SPARROW et al.: "Lipid binding by apolipoprotein A-I: Synthetic studies", & Pept. Struct. Biol. Funct., Proc. Am. Pept. Symp. 6th, 1979, 523-6, Abstract. *
CHEMICAL ABSTRACTS, Vol. 99, 1983, page 258, Ref. No. 154205b; Columbus, Ohio, US, P. VAINIO et al.: "Esterase type of activity possessed by human plasma apolipoprotein C-II and its synthetic fragments", & Chem. Phys. Lipids 1983, 33(1), 21-32, Abstract. *
Febs Letters, Vol. 170, No. 1, May 1984, pages 105-108; Elsevier Sc. Publ. B.V., R.C. LEBOEUF et al.: "Human apolipoprotein B: Partial amino acid sequence", Abstract. *
Journal of Biological Chemistry, Vol. 257, No. 8, April 25, 1982, pages 4171-4178; US, S.C. RALL Jr. et al.: "Human apolipoprotein E. The complete amino acid sequence", page 4171, column 1. *
See also references of WO8604144A1 *

Also Published As

Publication number Publication date
JPS62501770A (en) 1987-07-16
WO1986004144A1 (en) 1986-07-17
EP0209543A1 (en) 1987-01-28

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

AK Designated contracting states

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Designated state(s): AT BE CH DE FR GB IT LI LU NL SE

17P Request for examination filed

Effective date: 19870107

A4 Supplementary search report drawn up and despatched

Effective date: 19890711

17Q First examination report despatched

Effective date: 19910823

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19930504

RIN1 Information on inventor provided before grant (corrected)

Inventor name: SEN, ARUP

Inventor name: FAREED, GEORGE