EP0088540A3 - Dna sequences, recombinant dna molecules and processes for producing human immune interferon-like polypeptides - Google Patents

Dna sequences, recombinant dna molecules and processes for producing human immune interferon-like polypeptides Download PDF

Info

Publication number
EP0088540A3
EP0088540A3 EP83300805A EP83300805A EP0088540A3 EP 0088540 A3 EP0088540 A3 EP 0088540A3 EP 83300805 A EP83300805 A EP 83300805A EP 83300805 A EP83300805 A EP 83300805A EP 0088540 A3 EP0088540 A3 EP 0088540A3
Authority
EP
European Patent Office
Prior art keywords
polypeptides
human immune
immune interferon
dna sequences
recombinant dna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP83300805A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP0088540A2 (en
Inventor
Walter Charles Dr. Fiers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biogen Inc
Original Assignee
Biogen NV
Biogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen NV, Biogen Inc filed Critical Biogen NV
Publication of EP0088540A2 publication Critical patent/EP0088540A2/en
Publication of EP0088540A3 publication Critical patent/EP0088540A3/en
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/57—IFN-gamma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP83300805A 1982-02-22 1983-02-17 Dna sequences, recombinant dna molecules and processes for producing human immune interferon-like polypeptides Ceased EP0088540A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8205203 1982-02-22
GB8205203 1982-02-22

Publications (2)

Publication Number Publication Date
EP0088540A2 EP0088540A2 (en) 1983-09-14
EP0088540A3 true EP0088540A3 (en) 1984-10-17

Family

ID=10528520

Family Applications (1)

Application Number Title Priority Date Filing Date
EP83300805A Ceased EP0088540A3 (en) 1982-02-22 1983-02-17 Dna sequences, recombinant dna molecules and processes for producing human immune interferon-like polypeptides

Country Status (7)

Country Link
EP (1) EP0088540A3 (es)
JP (1) JPS5951792A (es)
AU (2) AU1167483A (es)
DK (1) DK73483A (es)
ES (1) ES519953A0 (es)
IL (1) IL67961A0 (es)
ZA (1) ZA831094B (es)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8406910D0 (en) * 1984-03-16 1984-04-18 Biogen Nv Gamma interferon
IL68100A0 (en) * 1982-03-24 1983-06-15 Takeda Chemical Industries Ltd Novel dna and use thereof
JPH0787797B2 (ja) * 1982-05-20 1995-09-27 サントリー株式会社 ヒト・ガンマ・インタ−フエロン様ポリペプチドの製造法
AU571460B2 (en) * 1982-09-27 1988-04-21 Cancer Institute Of Japanese Foundation For Cancer Research Alpha interferon dna, recombinant plasmid, engineered organism and alpha interferon polypeptide
US4966843A (en) * 1982-11-01 1990-10-30 Cetus Corporation Expression of interferon genes in Chinese hamster ovary cells
WO1984002129A1 (en) * 1982-11-22 1984-06-07 Takeda Chemical Industries Ltd Human immune interferon protein and process for its preparation
JPH0740925B2 (ja) * 1983-03-14 1995-05-10 協和醗酵工業株式会社 新規ヒトインタ−フエロン−γポリペプチド
ZA846554B (en) * 1983-09-20 1985-04-24 Hoffmann La Roche Immune interferon and method for its purification
US4604284A (en) * 1983-09-20 1986-08-05 Hoffmann-La Roche Inc. Homogeneous immune interferon fragment
US4476049A (en) * 1983-09-20 1984-10-09 Hoffmann-La Roche Inc. Method for the extraction of immune interferon
JPH0788398B2 (ja) * 1983-10-17 1995-09-27 サントリー株式会社 新規生理活性ポリペプチドおよびその製造法
US4855238A (en) 1983-12-16 1989-08-08 Genentech, Inc. Recombinant gamma interferons having enhanced stability and methods therefor
MX9203641A (es) * 1983-12-16 1992-07-01 Genentech Inc Interferones gamma recombinantes que poseen estabilidad mejorada y metodos biotecnologicos para su obtencion.
JPS60145098A (ja) * 1984-01-09 1985-07-31 Suntory Ltd 糖付加ポリペプチドの製造法
US4758512A (en) * 1984-03-06 1988-07-19 President And Fellows Of Harvard College Hosts and methods for producing recombinant products in high yields
DE3409966A1 (de) * 1984-03-19 1985-09-26 Hoechst Ag, 6230 Frankfurt Gentechnologisches verfahren zur herstellung von human-gammainterferon und mittel zur durchfuehrung dieses verfahrens
WO1985004420A1 (en) * 1984-03-29 1985-10-10 Takeda Chemical Industries, Ltd. Novel dna and its use
EP0158198A1 (en) * 1984-03-29 1985-10-16 Takeda Chemical Industries, Ltd. DNA and use thereof
DE3414831A1 (de) * 1984-04-19 1985-10-31 Hoechst Ag, 6230 Frankfurt Herstellung von polypeptiden mit human-gammainterferon-aktivitaet
IL71691A (en) * 1984-04-27 1991-04-15 Yeda Res & Dev Production of interferon-ypsilon
WO1985005618A1 (en) * 1984-06-06 1985-12-19 Takeda Chemical Industries, Ltd. Process for preparing interferon derivative
JPS60262594A (ja) * 1984-06-11 1985-12-25 Kanegafuchi Chem Ind Co Ltd ヒトインタ−フエロン−γ
CA1302320C (en) * 1984-06-11 1992-06-02 Hideo Niwa Expression of human cromosomal interferon-_ in animal cells
GB8414911D0 (en) * 1984-06-12 1984-07-18 Searle & Co Producing human gamma interferon
GB2164650A (en) * 1984-09-25 1986-03-26 Fujisawa Pharmaceutical Co Process for production of y-interferon
JPS6188875A (ja) * 1984-10-05 1986-05-07 Kanegafuchi Chem Ind Co Ltd ヒトインタ−フエロン−γ
IL76591A0 (en) * 1984-10-05 1986-02-28 Bioferon Biochem Substanz Pharmaceutical compositions containing ifn-ypsilon and processes for the preparation thereof
US4946674A (en) * 1984-10-05 1990-08-07 Bioferon Biochemische Substanzen Gmbh & Co. Process for treatment of rheumatic diseases
DE3521733A1 (de) * 1985-06-18 1986-12-18 Bioferon biochemische Substanzen GmbH & Co, 7958 Laupheim Verwendung von interferon-gamma (ifn-gamma) enthaltenden praeparationen zur systemischen behandlung von tumoren und viruserkrankungen in niedriger dosierung
JPS61108397A (ja) * 1984-10-31 1986-05-27 Green Cross Corp:The インタ−フエロン−γ蛋白質の製造法
FR2583429B1 (fr) * 1985-06-18 1989-11-03 Transgene Sa Vecteur d'expression de l'interferon u dans les cellules de mammifere, procede pour sa mise en oeuvre et produit obtenu et composition pharmaceutique contenant l'interferon u
GB8522336D0 (en) * 1985-09-09 1985-10-16 Biogen Nv Composition for treatment of allergies
JPH01501792A (ja) * 1986-03-17 1989-06-22 シェリング・コーポレーション γ型インターフェロンによる癌の治療
US4879111A (en) * 1986-04-17 1989-11-07 Cetus Corporation Treatment of infections with lymphokines
DE3751664T2 (de) * 1986-08-01 1996-06-05 Commw Scient Ind Res Org Rekombinanter impfstoff
DE3642096A1 (de) * 1986-12-10 1988-06-16 Boehringer Ingelheim Int Pferde-(gamma)-interferon
US5190751A (en) * 1987-01-20 1993-03-02 Schering Corporation Treatment of certain leukemias with a combination of gamma interferon and alpha interferon
NL8700927A (nl) * 1987-04-16 1988-11-16 Stichting Rega V Z W Anti-interferon-gamma-antilichamen; en hun therapeutische toepassing.
US6642032B2 (en) 1993-04-14 2003-11-04 Commonwealth Scientific And Industrial Research Organisation Uses of avian interferon gamma (IFN-γ)
AUPN154295A0 (en) * 1995-03-06 1995-03-30 Commonwealth Scientific And Industrial Research Organisation Nucleic acid molecule encoding a protein with avian gamma-interferon activity
PL356007A1 (en) 1999-11-12 2004-05-31 Maxygen Holdings Ltd Interferon gamma conjugates
YU32402A (sh) 1999-11-12 2005-03-15 Maxygen Holdings Ltd. Konjugati gama interferona
US7038015B2 (en) 2001-04-06 2006-05-02 Maxygen Holdings, Ltd. Interferon gamma polypeptide variants
US6958388B2 (en) 2001-04-06 2005-10-25 Maxygen, Aps Interferon gamma polypeptide variants
WO2004005341A2 (en) 2002-07-03 2004-01-15 Maxygen Holdings Ltd. Full-length interferon gamma polypeptide variants

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0063482A2 (en) * 1981-04-17 1982-10-27 Meloy Laboratories, Inc. Production of immune interferon and its mRNA
EP0077670A2 (en) * 1981-10-19 1983-04-27 Genentech, Inc. Human immune interferon
EP0083777A1 (en) * 1981-12-24 1983-07-20 Asahi Kasei Kogyo Kabushiki Kaisha Physiologically active peptide with between 147 and 162 amino acid residues
EP0089676A2 (en) * 1982-03-24 1983-09-28 Takeda Chemical Industries, Ltd. Novel DNA and use thereof
EP0095350A2 (en) * 1982-05-20 1983-11-30 Suntory Kabushiki Kaisha A method of producing human gamma-interferon-like polipeptide
EP0099084A2 (de) * 1982-07-12 1984-01-25 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Verfahren zur Herstellung von Interferon und Expressionsvektoren dafür

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0063482A2 (en) * 1981-04-17 1982-10-27 Meloy Laboratories, Inc. Production of immune interferon and its mRNA
EP0077670A2 (en) * 1981-10-19 1983-04-27 Genentech, Inc. Human immune interferon
EP0083777A1 (en) * 1981-12-24 1983-07-20 Asahi Kasei Kogyo Kabushiki Kaisha Physiologically active peptide with between 147 and 162 amino acid residues
EP0089676A2 (en) * 1982-03-24 1983-09-28 Takeda Chemical Industries, Ltd. Novel DNA and use thereof
EP0095350A2 (en) * 1982-05-20 1983-11-30 Suntory Kabushiki Kaisha A method of producing human gamma-interferon-like polipeptide
EP0099084A2 (de) * 1982-07-12 1984-01-25 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Verfahren zur Herstellung von Interferon und Expressionsvektoren dafür

Also Published As

Publication number Publication date
AU1167483A (en) 1983-09-01
EP0088540A2 (en) 1983-09-14
DK73483D0 (da) 1983-02-21
AU2964489A (en) 1989-08-24
DK73483A (da) 1983-08-23
JPS5951792A (ja) 1984-03-26
ZA831094B (en) 1983-11-30
IL67961A0 (en) 1983-06-15
ES8403969A1 (es) 1984-04-01
ES519953A0 (es) 1984-04-01

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Owner name: BIOGEN, INC.

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Effective date: 19930414

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Inventor name: FIERS, WALTER CHARLES, DR.