EP0084086A3 - Laser microsensor - Google Patents

Laser microsensor Download PDF

Info

Publication number
EP0084086A3
EP0084086A3 EP82109634A EP82109634A EP0084086A3 EP 0084086 A3 EP0084086 A3 EP 0084086A3 EP 82109634 A EP82109634 A EP 82109634A EP 82109634 A EP82109634 A EP 82109634A EP 0084086 A3 EP0084086 A3 EP 0084086A3
Authority
EP
European Patent Office
Prior art keywords
laser
microsensor
excitation
sample
time
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP82109634A
Other languages
German (de)
French (fr)
Other versions
EP0084086A2 (en
Inventor
Hans-Josef Dr. Heinen
Stefan Meier
Henning Vogt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Balzers und Leybold Deutschland Holding AG
Original Assignee
Leybold AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE3201264 priority Critical
Priority to DE19823201264 priority patent/DE3201264A1/en
Application filed by Leybold AG filed Critical Leybold AG
Publication of EP0084086A2 publication Critical patent/EP0084086A2/en
Publication of EP0084086A3 publication Critical patent/EP0084086A3/en
Application status is Withdrawn legal-status Critical

Links

Classifications

    • HELECTRICITY
    • H01BASIC ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/10Ion sources; Ion guns
    • H01J49/16Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/161Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission using photoionisation, e.g. by laser
    • H01J49/164Laser desorption/ionisation, e.g. matrix-assisted laser desorption/ionisation [MALDI]
    • HELECTRICITY
    • H01BASIC ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/26Mass spectrometers or separator tubes
    • H01J49/34Dynamic spectrometers
    • H01J49/40Time-of-flight spectrometers

Abstract

Bei einer Lasermikrosonde mit einem Pulslaser zur Anregung von Proben (1) und mit einem eine Flugstrecke (4) umfassenden Flugzeit-Massenspektrometer (4, 5) ist der Flugzeitstrecke (4) ein Elektrodensystem (9) vorgelagert, welches der Formung eines zeitlich definierten Ionenpulses aus dem durch die Anregung der Probe (1) entstehenden Plasma dient. At a laser microprobe with a pulse laser for excitation of the sample (1) and comprising a an air gap (4) time of flight mass spectrometer (4, 5) is preceded by the time of flight path (4), an electrode system (9), which is the formation of a temporally defined ionic pulse is from the by the excitation of the sample (1) emerging plasma.
EP82109634A 1982-01-16 1982-10-19 Laser microsensor Withdrawn EP0084086A3 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DE3201264 1982-01-16
DE19823201264 DE3201264A1 (en) 1982-01-16 1982-01-16 Laser microprobe

Publications (2)

Publication Number Publication Date
EP0084086A2 EP0084086A2 (en) 1983-07-27
EP0084086A3 true EP0084086A3 (en) 1984-02-22

Family

ID=6153253

Family Applications (1)

Application Number Title Priority Date Filing Date
EP82109634A Withdrawn EP0084086A3 (en) 1982-01-16 1982-10-19 Laser microsensor

Country Status (2)

Country Link
EP (1) EP0084086A3 (en)
DE (1) DE3201264A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4135504A1 (en) * 1991-10-28 1993-04-29 Spectro Mass Spectrometry Ges Programmable tax and data-recording system for flight-time mass spectrometer
US20020037517A1 (en) 1993-05-28 2002-03-28 Hutchens T. William Methods for sequencing biopolymers
JP3639594B2 (en) 1993-05-28 2005-04-20 ベイラー カレッジ オブ メディシン Method and apparatus for desorption and ionization of analytes
US6020208A (en) * 1994-05-27 2000-02-01 Baylor College Of Medicine Systems for surface-enhanced affinity capture for desorption and detection of analytes
US5641959A (en) * 1995-12-21 1997-06-24 Bruker-Franzen Analytik Gmbh Method for improved mass resolution with a TOF-LD source

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3307033A (en) * 1963-07-19 1967-02-28 William H Johnston Lab Inc Coincidence mass spectrometer with electrostatic means to separate positive and negative ions and detectors and method of use
FR1580234A (en) * 1968-05-15 1969-09-05

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3307033A (en) * 1963-07-19 1967-02-28 William H Johnston Lab Inc Coincidence mass spectrometer with electrostatic means to separate positive and negative ions and detectors and method of use
FR1580234A (en) * 1968-05-15 1969-09-05

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
APPLIED PHYSICS, Band 8, Nr. 4, Dezember 1975, Seiten 341-348, Springer-Verlag 1975, Heidelberg, DE. *
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY AND ION PHYSICS, Band 13, Nr. 1, 1974, Seiten 45-53, Elsevier Scientific Publishing Company, Amsterdam, NL. *
JOURNAL OF PHYSICS E, SCIENTIFIC INSTRUMENTS, Band 7, Nr. 5, Mai 1974, Seiten 364-368, London, GB. *
THE REVIEW OF SCIENTIFIC INSTRUMENTS, Band 40, Nr. 3, März 1969, Seiten 503-504, New York, USA *

Also Published As

Publication number Publication date
DE3201264A1 (en) 1983-07-28
EP0084086A2 (en) 1983-07-27

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Legal Events

Date Code Title Description
17P Request for examination filed

Effective date: 19821019

AK Designated contracting states:

Designated state(s): DE FR GB NL

AK Designated contracting states:

Designated state(s): DE FR GB NL

18D Deemed to be withdrawn

Effective date: 19850531

RIN1 Inventor (correction)

Inventor name: HEINEN, HANS-JOSEF, DR.

Inventor name: VOGT, HENNING

Inventor name: MEIER, STEFAN