ECSP055731A - ORAL FORMULATIONS - Google Patents

ORAL FORMULATIONS

Info

Publication number
ECSP055731A
ECSP055731A EC2005005731A ECSP055731A ECSP055731A EC SP055731 A ECSP055731 A EC SP055731A EC 2005005731 A EC2005005731 A EC 2005005731A EC SP055731 A ECSP055731 A EC SP055731A EC SP055731 A ECSP055731 A EC SP055731A
Authority
EC
Ecuador
Prior art keywords
oral formulations
cci
rapamycin
hydroxymethyl
hydroxy
Prior art date
Application number
EC2005005731A
Other languages
Spanish (es)
Inventor
Muhammad Ashraf
Eric J Benjamin
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of ECSP055731A publication Critical patent/ECSP055731A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Abstract

This invention provides solid oral formulations of rapamycin 42-ester with 3-hydroxy-2-(hydroxymethyl)-2-methylpropionic acid (CCI-779).
EC2005005731A 2002-09-17 2005-04-13 ORAL FORMULATIONS ECSP055731A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41126402P 2002-09-17 2002-09-17

Publications (1)

Publication Number Publication Date
ECSP055731A true ECSP055731A (en) 2005-07-06

Family

ID=32030658

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2005005731A ECSP055731A (en) 2002-09-17 2005-04-13 ORAL FORMULATIONS

Country Status (25)

Country Link
US (1) US20040077677A1 (en)
EP (1) EP1635830B1 (en)
JP (1) JP2006506353A (en)
KR (1) KR20050084559A (en)
CN (1) CN100415233C (en)
AT (1) ATE413163T1 (en)
AU (1) AU2003272489B2 (en)
BR (1) BR0314397A (en)
CA (1) CA2496332A1 (en)
CR (1) CR7791A (en)
DE (1) DE60324609D1 (en)
DK (1) DK1635830T3 (en)
EC (1) ECSP055731A (en)
ES (1) ES2315530T3 (en)
HK (1) HK1084050A1 (en)
IL (1) IL166824A0 (en)
MX (1) MXPA05002828A (en)
NO (1) NO20050836L (en)
NZ (1) NZ538781A (en)
PT (1) PT1635830E (en)
RU (1) RU2326654C2 (en)
SI (1) SI1635830T1 (en)
UA (1) UA81265C2 (en)
WO (1) WO2004026280A2 (en)
ZA (1) ZA200502220B (en)

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DE102005005449A1 (en) 2005-02-04 2006-08-10 Grünenthal GmbH Process for producing an anti-abuse dosage form
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Also Published As

Publication number Publication date
DE60324609D1 (en) 2008-12-18
JP2006506353A (en) 2006-02-23
UA81265C2 (en) 2007-12-25
EP1635830A2 (en) 2006-03-22
NO20050836L (en) 2005-04-15
CR7791A (en) 2007-10-01
DK1635830T3 (en) 2009-02-23
AU2003272489B2 (en) 2008-11-13
WO2004026280A2 (en) 2004-04-01
ES2315530T3 (en) 2009-04-01
NZ538781A (en) 2007-11-30
CA2496332A1 (en) 2004-04-01
ATE413163T1 (en) 2008-11-15
SI1635830T1 (en) 2009-02-28
WO2004026280A3 (en) 2005-12-01
AU2003272489A1 (en) 2004-04-08
CN1764459A (en) 2006-04-26
RU2005111222A (en) 2005-09-20
CN100415233C (en) 2008-09-03
HK1084050A1 (en) 2006-07-21
PT1635830E (en) 2008-12-31
EP1635830B1 (en) 2008-11-05
MXPA05002828A (en) 2005-05-27
RU2326654C2 (en) 2008-06-20
ZA200502220B (en) 2008-01-30
US20040077677A1 (en) 2004-04-22
IL166824A0 (en) 2006-01-15
BR0314397A (en) 2005-08-09
KR20050084559A (en) 2005-08-26

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