EA201590008A1 - Композиции и способы повышения эффективности бактерицидных средств контрацепции - Google Patents

Композиции и способы повышения эффективности бактерицидных средств контрацепции

Info

Publication number
EA201590008A1
EA201590008A1 EA201590008A EA201590008A EA201590008A1 EA 201590008 A1 EA201590008 A1 EA 201590008A1 EA 201590008 A EA201590008 A EA 201590008A EA 201590008 A EA201590008 A EA 201590008A EA 201590008 A1 EA201590008 A1 EA 201590008A1
Authority
EA
Eurasian Patent Office
Prior art keywords
compositions
bactericidal
methods
contraceptive
contraceptives
Prior art date
Application number
EA201590008A
Other languages
English (en)
Russian (ru)
Inventor
Уэнделл Гатри
Original Assignee
Ивофем, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49758600&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201590008(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ивофем, Инк. filed Critical Ивофем, Инк.
Publication of EA201590008A1 publication Critical patent/EA201590008A1/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Virology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Inorganic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Dispersion Chemistry (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
EA201590008A 2012-06-13 2013-03-15 Композиции и способы повышения эффективности бактерицидных средств контрацепции EA201590008A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261659368P 2012-06-13 2012-06-13
PCT/US2013/032510 WO2013187984A1 (en) 2012-06-13 2013-03-15 Compositions and methods for enhancing the efficacy of contraceptive microbicides

Publications (1)

Publication Number Publication Date
EA201590008A1 true EA201590008A1 (ru) 2015-05-29

Family

ID=49758600

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201590008A EA201590008A1 (ru) 2012-06-13 2013-03-15 Композиции и способы повышения эффективности бактерицидных средств контрацепции

Country Status (17)

Country Link
US (7) US20150202216A1 (https=)
EP (2) EP2861215A1 (https=)
JP (2) JP6352907B2 (https=)
KR (1) KR102062599B1 (https=)
CN (2) CN104487054A (https=)
AP (1) AP2014008149A0 (https=)
AU (2) AU2013274815B2 (https=)
BR (1) BR112014030984B1 (https=)
EA (1) EA201590008A1 (https=)
HK (1) HK1208809A1 (https=)
IL (1) IL235812B (https=)
MX (2) MX365905B (https=)
NZ (1) NZ703203A (https=)
SG (1) SG11201408243VA (https=)
UA (1) UA115876C2 (https=)
WO (1) WO2013187984A1 (https=)
ZA (1) ZA201500111B (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA201590008A1 (ru) * 2012-06-13 2015-05-29 Ивофем, Инк. Композиции и способы повышения эффективности бактерицидных средств контрацепции
JP2017501227A (ja) * 2013-12-19 2017-01-12 エヴォフェム,インク. アルギン酸をベースとする抗菌性化合物を使用して炎症と疾患を阻害するための組成物及び方法
US11419835B2 (en) * 2016-10-04 2022-08-23 Evofem, Inc. Method of treatment and prevention of bacterial vaginosis
USD920853S1 (en) * 2018-09-14 2021-06-01 Porsche Lizenz—und Handelsgesellschaft mbH & Co. KG Bicycle
US11850303B2 (en) 2020-10-27 2023-12-26 Uqora, Inc. Gel and a suppository and methods to provide the gel and suppository

Family Cites Families (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1213323B (it) * 1986-08-07 1989-12-20 Crinos Industria Farmaco Composizione per uso locale ad atti vita' spermicida virulicida ,disinfettante e/o battericida
US4999342A (en) * 1988-08-16 1991-03-12 Ortho Pharmaceutical Corporation Long lasting contraceptive suppository composition and methods of use
JP3202365B2 (ja) 1992-12-04 2001-08-27 株式会社紀文フードケミファ オリゴマンヌロン酸を重合度によって分離する方法
US5592949A (en) 1994-06-29 1997-01-14 Moench; Thomas R. Device for acidic buffering and method for inactivation of pathogens
US5667492A (en) * 1994-10-07 1997-09-16 Columbia Laboratories, Inc. Use and composition of an anti-sexually transmitted diseases formulation
FR2728464B1 (fr) * 1994-12-22 1997-04-30 Innothera Lab Sa Forme galenique unitaire, son procede d'obtention et ses utilisations
US6093394A (en) 1997-04-11 2000-07-25 Gynelogix, Inc. Vaginal lactobacillus medicant
AU1661901A (en) 1999-11-24 2001-06-04 Cargill Dow Llc Improved lactic acid processing; methods; arrangements; and, products
WO2001066084A2 (en) * 2000-03-07 2001-09-13 Rush-Presbyterian-St. Luke's Medical Center Compositions and methods for trapping and inactivating pathogenic microbes and spermatozoa
JP2009102407A (ja) 2001-03-08 2009-05-14 Rohto Pharmaceut Co Ltd Gリッチなアルギン酸含有組成物
US20020177624A1 (en) 2001-03-16 2002-11-28 Calvin Hanna Acetate-lactate buffering vaginal gel and for method of making same and treating bacterial vaginosis
ITMI20010913A1 (it) 2001-05-04 2002-11-04 Univ Pavia Composizioni a rilascio controllato di acido lattico a livello vaginale
CA2449247A1 (en) 2001-06-11 2002-12-19 Merck & Co., Inc. A method for treating inflammatory diseases by administering a ppar-delta agonist
US20060105008A1 (en) 2002-03-28 2006-05-18 Nawaz Ahmad Compositions and methods for reducing vaginal pH
US20130150810A1 (en) 2002-04-30 2013-06-13 The Population Council, Inc. Intravaginal ring for the delivery of unique combinations of antimicrobial compositions
JP4712380B2 (ja) 2002-07-26 2011-06-29 三笠製薬株式会社 外用剤
US7820145B2 (en) 2003-08-04 2010-10-26 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam
ES2752773T3 (es) 2003-06-13 2020-04-06 Idh Holding Aps Tratamiento de los síntomas asociados a la vaginosis bacteriana
US20050272700A1 (en) 2004-05-10 2005-12-08 Servet Buyuktimkin Topical treatment and prevention of human papilloma virus (HPV) infection
RU2257197C1 (ru) 2004-05-12 2005-07-27 Дулькис Мария Дмитриевна Вагинальные суппозитории, обладающие контрацептивным действием
UA93354C2 (ru) * 2004-07-09 2011-02-10 Гилиад Сайенсиз, Инк. Местный противовирусный препарат
CN101534863A (zh) 2006-11-10 2009-09-16 日本乐敦制药株式会社 用于向皮肤或粘膜施用的组合物
US7659259B2 (en) 2006-12-21 2010-02-09 Bausch & Lomb Incorporated Method of treating inflammation of the eye
ES2482190T3 (es) 2007-03-30 2014-08-01 Laccure Ab Uso de oligómeros de ácido láctico en el tratamiento de infecciones ginecológicas
JP2010528052A (ja) 2007-05-24 2010-08-19 ニューヨーク ブラッド センター, インコーポレイテッド 生体接着性ジェルを提供する迅速に分散し得る膣錠剤
US8464245B2 (en) 2007-06-27 2013-06-11 Flexera Software Llc Method and system for software virtualization directly from an installation package
TW200927141A (en) 2007-11-22 2009-07-01 Bayer Schering Pharma Oy Vaginal delivery system
CA2721457A1 (en) * 2008-04-16 2009-10-22 Cipla Limited Topical combinations comprising an antimycotic agent and an antiviral agent
CN101559036B (zh) * 2008-04-18 2012-02-08 上海医药工业研究院 一种阴道用避孕凝胶组合物及其制备方法和应用
WO2009155118A1 (en) 2008-05-30 2009-12-23 Reprotect, Inc. Compositions and methods for inactivation of pathogens at genital tract surfaces
EP2130531A1 (en) 2008-06-04 2009-12-09 Rolf Kullgren AB Vaginal suppository comprising lactic acid
BRPI0803568B8 (pt) * 2008-08-14 2021-05-25 Biolab San Us Farm Ltda composição mucoaderente
US20120070476A1 (en) 2009-05-29 2012-03-22 Moench Thomas R Compositions and Methods for Inactivation of Pathogens at Genital Tract Surfaces
EP2440560A1 (en) 2009-06-10 2012-04-18 Ultimorphix Technologies B.v. The succinate of tenofovir disoproxil
WO2012151237A1 (en) 2011-05-02 2012-11-08 Aptalis Pharmatech, Inc. Rapid dissolve tablet compositions for vaginal administration
JP5986632B2 (ja) 2011-06-28 2016-09-06 メディシス ファーマシューティカル コーポレイション 高用量粘膜接着性メトロニダゾール水系ゲル製剤および細菌性膣炎を治療するためのそれらの使用
KR20150002676A (ko) 2012-03-19 2015-01-07 독토르. 아우구스트 볼프 게엠베하 운트 코. 카게 아르쯔네이미텔 질 염증에서의 병원성 질 균막의 예방 및 치료를 위한 양쪽성 계면활성제의 용도
EA201590008A1 (ru) * 2012-06-13 2015-05-29 Ивофем, Инк. Композиции и способы повышения эффективности бактерицидных средств контрацепции
EP2968109A2 (en) 2012-09-14 2016-01-20 Cipla Limited Topical pharmaceutical composition comprising tenofovir, an antibacterial agent and, optonally ciclopirox
WO2015027071A1 (en) 2013-08-21 2015-02-26 Georgia Regents Research Institute, Inc. Gpr81 agonists and methods thereof for promoting production of secretory iga
WO2015070072A1 (en) 2013-11-07 2015-05-14 Evofem, Inc. Methods for manufacturing contraceptive microbicides with antiviral properties
JP2017501227A (ja) 2013-12-19 2017-01-12 エヴォフェム,インク. アルギン酸をベースとする抗菌性化合物を使用して炎症と疾患を阻害するための組成物及び方法
AU2015201042A1 (en) 2014-02-28 2015-09-17 Macfarlane Burnet Institute For Medical Research And Public Health Pty Ltd Therapeutic Method
US20190209502A1 (en) 2016-09-12 2019-07-11 Evofem, Inc. Combination gel for sexually transmitted infections
US11419835B2 (en) 2016-10-04 2022-08-23 Evofem, Inc. Method of treatment and prevention of bacterial vaginosis

Also Published As

Publication number Publication date
EP2861215A4 (en) 2015-04-22
EP2861215A1 (en) 2015-04-22
AU2017206199B2 (en) 2019-03-28
JP2018109034A (ja) 2018-07-12
BR112014030984A2 (pt) 2017-06-27
AU2017206199A1 (en) 2017-08-03
JP2015519395A (ja) 2015-07-09
EP3308771A1 (en) 2018-04-18
US11439610B2 (en) 2022-09-13
AU2013274815A1 (en) 2015-01-22
CN104487054A (zh) 2015-04-01
AP2014008149A0 (en) 2014-12-31
US20230241013A1 (en) 2023-08-03
KR102062599B1 (ko) 2020-01-06
KR20150018636A (ko) 2015-02-23
MX2019007176A (es) 2019-08-16
IL235812B (en) 2020-05-31
JP6352907B2 (ja) 2018-07-04
US20170128396A1 (en) 2017-05-11
US9566232B2 (en) 2017-02-14
US10568855B2 (en) 2020-02-25
HK1208809A1 (en) 2016-03-18
MX2014015307A (es) 2015-07-06
US20150202216A1 (en) 2015-07-23
IL235812A0 (en) 2015-01-29
US11992472B2 (en) 2024-05-28
UA115876C2 (uk) 2018-01-10
BR112014030984B1 (pt) 2022-05-24
WO2013187984A1 (en) 2013-12-19
US20200147015A1 (en) 2020-05-14
US20160008276A1 (en) 2016-01-14
CN110693812A (zh) 2020-01-17
SG11201408243VA (en) 2015-01-29
ZA201500111B (en) 2016-01-27
AU2013274815B2 (en) 2017-04-20
MX365905B (es) 2019-06-18
US20190133978A1 (en) 2019-05-09
NZ703203A (en) 2016-07-29
JP6738573B2 (ja) 2020-08-12
US20240423936A1 (en) 2024-12-26

Similar Documents

Publication Publication Date Title
EA202092456A3 (ru) Комбинированная терапия, включающая ингибитор mdm2 и один или более дополнительных фармацевтически активных агентов, для лечения различных видов рака
EA201591004A1 (ru) Производные бороновой кислоты и их терапевтическое применение
CL2017002792A1 (es) Derivados de ciclohexano sustituido con amido
ECSP12012349A (es) Agentes inductores de apoptosis contra el cáncer y de enfermedades inmunes y autoinmunes
ECSP12012348A (es) Agentes inductores de apoptosis contra el cáncer y de enfermedades inmunes y autoinmunes
UA115558C2 (uk) Алкілпіримідинові похідні для лікування вірусних інфекцій та подальших захворювань
EA201692301A1 (ru) Производные бороновой кислоты и их терапевтическое применение
MX2016015093A (es) Derivados de acido boronico y sus usos terapeuticos.
EP2709453A4 (en) USE OF THIAZOLIDE COMPOUNDS FOR THE PREVENTION AND TREATMENT OF VIRUS DISEASES, CANCER AND DISEASES THROUGH INTRA-CELLULAR INFECTIONS
EA201492290A1 (ru) Составы и способы для вагинальной доставки антипрогестинов
EA201590008A1 (ru) Композиции и способы повышения эффективности бактерицидных средств контрацепции
CL2016002276A1 (es) Composiciones tópicas que comprenden un extracto de coriolus versicolor para aumentar la autoinmunidad
MX2015003262A (es) Composicion farmaceutica topica.
EA201500851A1 (ru) ЭСТРА-1,3,5(10),16-ТЕТРАЕН-3-КАРБОКСАМИДЫ ДЛЯ ИНГИБИРОВАНИЯ 17β-ГИДРОКСИСТЕРОИД-ДЕГИДРОГЕНАЗЫ (AKR1C3)
AR091739A1 (es) Composiciones y metodos para reducir el riesgo cardiometabolico
CL2017002803A1 (es) Compuestos heterocíclicos y su uso en la prevención o tratamiento de las infecciones bacterianas
MA38975A1 (fr) Dispositif d'administration par voie intra-utérine
MX2021001742A (es) Composiciones y metodos para inhibir la inflamacion y las enfermedades utilizando un compuesto antimicrobiano con base en acido alginico.
NZ707174A (en) Compositions and methods of use of an inappetance-controlling compound
MX2014011218A (es) Uso de agentes tensoactivos anfotericos para la prevencion y tratamiento de biopeliculas vaginales patogenas en infecciones vaginales.
CL2015002188A1 (es) Agentes analgésicos oculares tópicos
EA201491167A1 (ru) Вагинальное кольцо, содержащее мелоксикам и агент для модулирования высвобождения активного ингредиента, для применения у женщин в качестве контрацептива для постоянного использования
EA201491922A1 (ru) ВНУТРИМАТОЧНОЕ ПРИМЕНЕНИЕ 18-МЕТИЛ-15β,16β-МЕТИЛЕН-19-НОР-20-СПИРОКС-4-ЕН-3-ОНОВ, ВНУТРИМАТОЧНЫЕ СИСТЕМЫ, СОДЕРЖАЩИЕ 18-МЕТИЛ-15β,16β-МЕТИЛЕН-19-НОР-20-СПИРОКС-4-ЕН-3-ОНЫ, А ТАКЖЕ ИХ ПРИМЕНЕНИЕ ПРИ КОНТРАЦЕПЦИИ И ЛЕЧЕНИИ ГИНЕКОЛОГИЧЕСКИХ ЗАБОЛЕВАНИЙ
TH156853A (th) องค์ประกอบ และวิธีสำหรับการปรับเพิ่มประสิทธิภาพของสารฆ่าจุลชีพเชิงคุมกำเนิด
IN2013MU03582A (https=)