EA200100261A1 - Производные тиазолиновой кислоты (варианты) и способ лечения болезненного состояния (варианты) - Google Patents

Производные тиазолиновой кислоты (варианты) и способ лечения болезненного состояния (варианты)

Info

Publication number
EA200100261A1
EA200100261A1 EA200100261A EA200100261A EA200100261A1 EA 200100261 A1 EA200100261 A1 EA 200100261A1 EA 200100261 A EA200100261 A EA 200100261A EA 200100261 A EA200100261 A EA 200100261A EA 200100261 A1 EA200100261 A1 EA 200100261A1
Authority
EA
Eurasian Patent Office
Prior art keywords
options
acid derivatives
tiazolinic
treatment
disease condition
Prior art date
Application number
EA200100261A
Other languages
English (en)
Russian (ru)
Inventor
Раймонд Дж. Джуниор Бергерон
Original Assignee
Юниверсити Оф Флорида Рисёч Фаундейшн, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Юниверсити Оф Флорида Рисёч Фаундейшн, Инк. filed Critical Юниверсити Оф Флорида Рисёч Фаундейшн, Инк.
Publication of EA200100261A1 publication Critical patent/EA200100261A1/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/4261,3-Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/04Chelating agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Obesity (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychiatry (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Game Rules And Presentations Of Slot Machines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyrrole Compounds (AREA)
EA200100261A 1998-08-31 1999-08-31 Производные тиазолиновой кислоты (варианты) и способ лечения болезненного состояния (варианты) EA200100261A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/144,103 US6083966A (en) 1998-08-31 1998-08-31 Thiazoline acid derivatives
PCT/US1999/019691 WO2000012493A1 (en) 1998-08-31 1999-08-31 Thiazoline acid derivatives

Publications (1)

Publication Number Publication Date
EA200100261A1 true EA200100261A1 (ru) 2001-10-22

Family

ID=22507049

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200100261A EA200100261A1 (ru) 1998-08-31 1999-08-31 Производные тиазолиновой кислоты (варианты) и способ лечения болезненного состояния (варианты)

Country Status (23)

Country Link
US (9) US6083966A (https=)
EP (1) EP1109795B1 (https=)
JP (3) JP4817498B2 (https=)
KR (1) KR20010074907A (https=)
CN (1) CN100455574C (https=)
AT (1) ATE317392T1 (https=)
AU (1) AU759851B2 (https=)
BR (1) BR9913441B1 (https=)
CA (1) CA2342210C (https=)
CZ (1) CZ2001711A3 (https=)
DE (1) DE69929807T2 (https=)
EA (1) EA200100261A1 (https=)
ES (1) ES2260933T3 (https=)
HU (1) HUP0103165A3 (https=)
IL (2) IL141611A0 (https=)
NO (1) NO321028B1 (https=)
NZ (1) NZ509899A (https=)
PL (1) PL346852A1 (https=)
PT (1) PT1109795E (https=)
TR (1) TR200100541T2 (https=)
UA (1) UA57161C2 (https=)
WO (1) WO2000012493A1 (https=)
YU (1) YU21801A (https=)

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CA2427146A1 (en) * 2000-10-25 2002-07-18 Mayo Foundation For Medical Education And Research Transcobalamin binding conjugates useful for treating abnormal cellular proliferation
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TR201910900T4 (tr) * 2005-04-04 2019-08-21 Univ Florida Desferritiyokin polieter analogları.
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WO2008115433A1 (en) * 2007-03-15 2008-09-25 University Of Florida Desferrithiocin polyether analogues
MY163516A (en) * 2008-07-14 2017-09-15 Ferrokin Biosciences Inc Novel salts and polymorphs of desazadesferrithiocin polyether analogues as metal chelation agents
EP2566854A4 (en) 2010-05-04 2013-11-06 Shire Llc DESAZADESFERROTHIOCIN AND DEAZADESFERROTHIOCIN POLYETHER ANALOGS AS METAL CHELATORS
CN103562379A (zh) * 2011-05-19 2014-02-05 国立大学法人德岛大学 细胞分化诱导剂以及分化诱导方法
EP3620161A1 (en) 2011-12-16 2020-03-11 University of Florida Research Foundation, Inc. Uses of 4'-desferrithiocin analogs
JP6353751B2 (ja) * 2013-09-25 2018-07-04 国立大学法人電気通信大学 新規複素環式化合物及びその塩、並びに、発光基質組成物
AU2014352780A1 (en) * 2013-11-22 2016-06-09 University Of Florida Research Foundation, Inc. Desferrithiocin analogs and uses thereof
KR20170140306A (ko) 2015-04-27 2017-12-20 유니버시티 오브 플로리다 리서치 파운데이션, 인코포레이티드 대사적으로 프로그램화된 금속 킬레이트화제 및 그의 용도

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US20040044220A1 (en) * 2002-08-22 2004-03-04 University Of Florida Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin
JP2007505044A (ja) 2003-09-09 2007-03-08 ユニバーシティ オブ フロリダ リサーチ ファウンデイション、インコーポレイテッド ポリアミン−金属キレーター接合体
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WO2006055412A1 (en) 2004-11-19 2006-05-26 Shiva Biomedical, Llc Methods of treating erythropoietin-resistance
TR201910900T4 (tr) 2005-04-04 2019-08-21 Univ Florida Desferritiyokin polieter analogları.
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WO2008115433A1 (en) * 2007-03-15 2008-09-25 University Of Florida Desferrithiocin polyether analogues

Also Published As

Publication number Publication date
WO2000012493A9 (en) 2002-04-11
HK1035720A1 (en) 2003-04-24
US6083966A (en) 2000-07-04
JP5520875B2 (ja) 2014-06-11
CN1313856A (zh) 2001-09-19
US20030236417A1 (en) 2003-12-25
EP1109795A4 (en) 2002-01-16
CZ2001711A3 (cs) 2001-09-12
US7531563B2 (en) 2009-05-12
YU21801A (sh) 2005-07-19
JP4817498B2 (ja) 2011-11-16
US6525080B1 (en) 2003-02-25
US20050033057A1 (en) 2005-02-10
EP1109795A1 (en) 2001-06-27
WO2000012493A1 (en) 2000-03-09
CA2342210A1 (en) 2000-03-09
CA2342210C (en) 2009-03-10
HUP0103165A2 (hu) 2002-01-28
NO321028B1 (no) 2006-02-27
AU759851B2 (en) 2003-05-01
HUP0103165A3 (en) 2003-03-28
NZ509899A (en) 2003-12-19
ES2260933T3 (es) 2006-11-01
JP2002523500A (ja) 2002-07-30
IL141611A0 (en) 2002-03-10
NO20011003L (no) 2001-02-27
TR200100541T2 (tr) 2001-11-21
IL141611A (en) 2006-12-31
USRE39132E1 (en) 2006-06-13
BR9913441A (pt) 2001-10-23
US6521652B1 (en) 2003-02-18
PL346852A1 (en) 2002-03-11
KR20010074907A (ko) 2001-08-09
US20070238767A1 (en) 2007-10-11
NO20011003D0 (no) 2001-02-27
CN100455574C (zh) 2009-01-28
US7126004B2 (en) 2006-10-24
DE69929807D1 (de) 2006-04-20
US20100094016A1 (en) 2010-04-15
AU5789799A (en) 2000-03-21
DE69929807T2 (de) 2006-11-02
JP2014065730A (ja) 2014-04-17
BR9913441B1 (pt) 2013-10-29
EP1109795B1 (en) 2006-02-08
JP2011178797A (ja) 2011-09-15
US6559315B1 (en) 2003-05-06
US8008502B2 (en) 2011-08-30
ATE317392T1 (de) 2006-02-15
UA57161C2 (uk) 2003-06-16
PT1109795E (pt) 2006-06-30

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