EA199900286A1 - Новые пикорнавирусы, вакцины и диагностические наборы - Google Patents
Новые пикорнавирусы, вакцины и диагностические наборыInfo
- Publication number
- EA199900286A1 EA199900286A1 EA199900286A EA199900286A EA199900286A1 EA 199900286 A1 EA199900286 A1 EA 199900286A1 EA 199900286 A EA199900286 A EA 199900286A EA 199900286 A EA199900286 A EA 199900286A EA 199900286 A1 EA199900286 A1 EA 199900286A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- picornaviruses
- protein
- sequence
- vaccines
- syndrome
- Prior art date
Links
- 238000009007 Diagnostic Kit Methods 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 241000709664 Picornaviridae Species 0.000 abstract 7
- 102000004169 proteins and genes Human genes 0.000 abstract 4
- 108090000623 proteins and genes Proteins 0.000 abstract 4
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 206010000234 Abortion spontaneous Diseases 0.000 abstract 1
- 208000031229 Cardiomyopathies Diseases 0.000 abstract 1
- 206010008874 Chronic Fatigue Syndrome Diseases 0.000 abstract 1
- 208000035895 Guillain-Barré syndrome Diseases 0.000 abstract 1
- 206010049567 Miller Fisher syndrome Diseases 0.000 abstract 1
- 206010028372 Muscular weakness Diseases 0.000 abstract 1
- 208000009525 Myocarditis Diseases 0.000 abstract 1
- 108091092724 Noncoding DNA Proteins 0.000 abstract 1
- 241000220317 Rosa Species 0.000 abstract 1
- 208000034972 Sudden Infant Death Diseases 0.000 abstract 1
- 206010042440 Sudden infant death syndrome Diseases 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 239000002299 complementary DNA Substances 0.000 abstract 1
- 201000001981 dermatomyositis Diseases 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000002483 medication Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 201000006417 multiple sclerosis Diseases 0.000 abstract 1
- 208000029766 myalgic encephalomeyelitis/chronic fatigue syndrome Diseases 0.000 abstract 1
- 230000036473 myasthenia Effects 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 208000005987 polymyositis Diseases 0.000 abstract 1
- 210000003786 sclera Anatomy 0.000 abstract 1
- 208000000995 spontaneous abortion Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/085—Picornaviridae, e.g. coxsackie virus, echovirus, enterovirus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Endocrinology (AREA)
Abstract
Открыта новая группа пикорнавирусов. Пикорнавирусы настоящего изобретения содержат некодирующий участок в своем геноме, нуклеотидная последовательность которого соответствует последовательности кДНК (1), или гомологичным последовательностям, имеющим, по меньшей мере, 75% гомологии с Последовательностью SEQ ID № 1, и эти вирусы вызывают заболевания млекопитающих. Другие аспекты этого изобретения содержат белок, относящийся к белку пикорнавирусов, антисыворотку или антитела, направленные против белка пикорнавирусов, антиген, представляющий собой белок пикорнавирусов, диагностические наборы, вакцины, использование пикорнавирусов в лекарственных препаратах, в частности, для лечения или предупреждения миокардита, кардиомиопатии, синдрома Гийена-Барре, сахарного диабета, рассеянного склероза, синдрома хронической усталости, миастении тяжелой псевдопаралитической, бокового амиотрофического склероза, дерматомиозита, полимиозита, спонтанного аборта и синдрома внезапной младенческой смерти, а также способы лечения заболеваний, вызванных пикорнавирусами.Международная заявка была опубликована вместе с отчетом о международном поиске.Последовательность SEQ ID № 1 (Ljungan 87-012)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9603305A SE9603305D0 (sv) | 1996-09-11 | 1996-09-11 | New picornaviruses, vaccines and diagnostic kits |
| PCT/SE1997/001515 WO1998011133A1 (en) | 1996-09-11 | 1997-09-09 | New picornaviruses, vaccines and diagnostic kits |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA199900286A1 true EA199900286A1 (ru) | 2000-04-24 |
Family
ID=20403847
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA199900286A EA199900286A1 (ru) | 1996-09-11 | 1997-09-09 | Новые пикорнавирусы, вакцины и диагностические наборы |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US7101554B2 (ru) |
| EP (1) | EP0941240B1 (ru) |
| JP (1) | JP4440345B2 (ru) |
| AT (1) | ATE278709T1 (ru) |
| AU (1) | AU4143597A (ru) |
| DE (1) | DE69731106T2 (ru) |
| EA (1) | EA199900286A1 (ru) |
| ES (1) | ES2229386T3 (ru) |
| SE (1) | SE9603305D0 (ru) |
| WO (1) | WO1998011133A1 (ru) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9603305D0 (sv) * | 1996-09-11 | 1996-09-11 | Bo Niklasson | New picornaviruses, vaccines and diagnostic kits |
| GB0120437D0 (en) * | 2001-08-22 | 2001-10-17 | Nya Apodemus Ab | Diabetic model |
| AU2003228072A1 (en) * | 2002-04-23 | 2003-11-10 | Susanne Johansson | A new family of picornaviruses |
| DE602004014728D1 (de) | 2003-02-21 | 2008-08-14 | Apodemus Ab | Behandlung von durch das ljungan-virus ausgelösten erkrankungen durch verwendung von pleconaril |
| AU2006343645B2 (en) * | 2006-05-01 | 2011-12-22 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention | Methods and agents for detecting Parechovirus |
| US8326439B2 (en) * | 2008-04-16 | 2012-12-04 | Nevro Corporation | Treatment devices with delivery-activated inflatable members, and associated systems and methods for treating the spinal cord and other tissues |
| US20130071421A1 (en) * | 2009-10-02 | 2013-03-21 | W. Ian Lipkin | Turkey viral hepatitis virus and uses thereof |
| US9572528B1 (en) | 2012-08-06 | 2017-02-21 | Los Angeles Biomedical Research Insitute at Harbor-UCLA Medical Center | Monitor for SIDS research and prevention |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5229111A (en) * | 1991-01-31 | 1993-07-20 | Wiscosnin Alumni Research Foundation | Method of inhibiting picornavirus disease |
| SE9603305D0 (sv) * | 1996-09-11 | 1996-09-11 | Bo Niklasson | New picornaviruses, vaccines and diagnostic kits |
-
1996
- 1996-09-11 SE SE9603305A patent/SE9603305D0/xx unknown
-
1997
- 1997-09-09 US US09/147,801 patent/US7101554B2/en not_active Expired - Fee Related
- 1997-09-09 AT AT97939321T patent/ATE278709T1/de not_active IP Right Cessation
- 1997-09-09 EP EP97939321A patent/EP0941240B1/en not_active Expired - Lifetime
- 1997-09-09 DE DE69731106T patent/DE69731106T2/de not_active Expired - Lifetime
- 1997-09-09 AU AU41435/97A patent/AU4143597A/en not_active Abandoned
- 1997-09-09 ES ES97939321T patent/ES2229386T3/es not_active Expired - Lifetime
- 1997-09-09 WO PCT/SE1997/001515 patent/WO1998011133A1/en active IP Right Grant
- 1997-09-09 EA EA199900286A patent/EA199900286A1/ru unknown
- 1997-09-09 JP JP51356498A patent/JP4440345B2/ja not_active Expired - Fee Related
-
2006
- 2006-06-07 US US11/448,321 patent/US20070003573A1/en not_active Abandoned
- 2006-06-29 US US11/477,709 patent/US7855277B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ATE278709T1 (de) | 2004-10-15 |
| DE69731106T2 (de) | 2006-02-23 |
| SE9603305D0 (sv) | 1996-09-11 |
| EP0941240B1 (en) | 2004-10-06 |
| JP4440345B2 (ja) | 2010-03-24 |
| US7855277B2 (en) | 2010-12-21 |
| EP0941240A1 (en) | 1999-09-15 |
| ES2229386T3 (es) | 2005-04-16 |
| WO1998011133A1 (en) | 1998-03-19 |
| US20030044960A1 (en) | 2003-03-06 |
| US20070003573A1 (en) | 2007-01-04 |
| DE69731106D1 (de) | 2004-11-11 |
| US7101554B2 (en) | 2006-09-05 |
| US20070003574A1 (en) | 2007-01-04 |
| AU4143597A (en) | 1998-04-02 |
| JP2001500503A (ja) | 2001-01-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US6395306B1 (en) | Bee venom protein and gene encoding same | |
| HU211879A9 (en) | Cytotoxic lymphocyte maturation factor and monoclonal antibodies directed thereto | |
| KR910000183A (ko) | 재조합 포자충증 백신 | |
| DK0853633T3 (da) | Humant monoklonalt antistof imod hepatitis B virus overfladeantigen (HBVsAg) | |
| EA199900286A1 (ru) | Новые пикорнавирусы, вакцины и диагностические наборы | |
| Potter | Plasma cell neoplasia in a single host: a mosaic of different protein-producing cell types | |
| ES8500997A1 (es) | Un metodo para producir un peptido. | |
| Hilgers et al. | Immunologic, virologic, and genetic aspects of mammary tumor virus-induced cell-surface antigens: presence of these antigens and the Thy 1.2 antigen on murine mammary gland and tumor cells | |
| CN1305589A (zh) | 采用还原剂的改进型免疫诊断分析 | |
| DE69726734D1 (de) | Menschliche monoklonale antikörper gegen das hepatitis b oberflächenantigen | |
| DE3584872D1 (de) | Verfahren zur herstellung von monoklonalen antikoerpern gegen hbsag. | |
| NO954135L (no) | Fiskebukspyttkjertel-sykdomsvirus | |
| CA2153494A1 (en) | Novel parasitic helminth proteins | |
| JP4880116B2 (ja) | 劇症ｃ型肝炎ウイルス株の遺伝子 | |
| JP4219987B2 (ja) | ヘモフィルス・パラガリナルム由来新規ポリペプチド及びその製法 | |
| KR890014127A (ko) | 생 조합 백신 | |
| Koszinowski et al. | Recognition of alterations induced by early vaccinia surface antigens and dependence of virus-specific lysis on H-2 antigen concentration on target cells | |
| FR2658204B1 (ru) | ||
| Müllbacher et al. | Alloreactive Cytotoxic T Lymphocytes Lyse Syngeneic Influenza‐Infected Tumour Cell Targets | |
| JP4452510B2 (ja) | ダニのキチナーゼ | |
| JPWO2003072781A1 (ja) | ダニのガレクチン | |
| Young et al. | Antigenic activity of tryptic peptides of tobacco mosaic virus protein | |
| CA2049883A1 (en) | Monoclonal antibody specifically reactive with human perforin | |
| Kopelovich | Immunochemical pattern of aspartate aminotransferase isozymes in several rodents and in Ehrlich ascites cells | |
| JP2006325497A (ja) | マダニのアスパラギン酸プロテアーゼ |