EA199800096A1 - Способ получения промежуточных продуктов для синтеза карбапенема - Google Patents
Способ получения промежуточных продуктов для синтеза карбапенемаInfo
- Publication number
- EA199800096A1 EA199800096A1 EA199800096A EA199800096A EA199800096A1 EA 199800096 A1 EA199800096 A1 EA 199800096A1 EA 199800096 A EA199800096 A EA 199800096A EA 199800096 A EA199800096 A EA 199800096A EA 199800096 A1 EA199800096 A1 EA 199800096A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- intermediate products
- obtaining intermediate
- carbapenem synthesis
- carbapenem
- synthesis
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- YZBQHRLRFGPBSL-RXMQYKEDSA-N carbapenem Chemical compound C1C=CN2C(=O)C[C@H]21 YZBQHRLRFGPBSL-RXMQYKEDSA-N 0.000 title 1
- 239000013067 intermediate product Substances 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 230000002194 synthesizing effect Effects 0.000 abstract 1
- -1 triethylsilyl Chemical group 0.000 abstract 1
- 125000000026 trimethylsilyl group Chemical group [H]C([H])([H])[Si]([*])(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/02—Preparation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
- C07F7/1872—Preparation; Treatments not provided for in C07F7/20
- C07F7/188—Preparation; Treatments not provided for in C07F7/20 by reactions involving the formation of Si-O linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58595P | 1995-06-28 | 1995-06-28 | |
| GBGB9602921.0A GB9602921D0 (en) | 1996-02-13 | 1996-02-13 | Improved process for synthesizing carbapenem intermediates |
| PCT/US1996/010783 WO1997001564A1 (en) | 1995-06-28 | 1996-06-24 | Improved process for synthesizing carbapenem intermediates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA199800096A1 true EA199800096A1 (ru) | 1998-08-27 |
Family
ID=26308678
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA199800096A EA199800096A1 (ru) | 1995-06-28 | 1996-06-24 | Способ получения промежуточных продуктов для синтеза карбапенема |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0836607A1 (cs) |
| JP (1) | JPH11513979A (cs) |
| KR (1) | KR19990028406A (cs) |
| CN (1) | CN1193322A (cs) |
| AR (1) | AR002507A1 (cs) |
| AU (1) | AU696543B2 (cs) |
| BR (1) | BR9609338A (cs) |
| CA (1) | CA2224439A1 (cs) |
| CZ (1) | CZ419097A3 (cs) |
| EA (1) | EA199800096A1 (cs) |
| HU (1) | HUP9903016A3 (cs) |
| SK (1) | SK176597A3 (cs) |
| WO (1) | WO1997001564A1 (cs) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2732619A1 (en) | 2008-07-30 | 2010-02-04 | Ranbaxy Laboratories Limited | Process for the preparation of carbapenem compounds |
| WO2011048583A1 (en) | 2009-10-23 | 2011-04-28 | Ranbaxy Laboratories Limited | Process for the preparation of carbapenem compounds |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683301A (en) * | 1982-04-08 | 1987-07-28 | Bristol-Myers Company | Carbapenem antibiotics |
| JP2675625B2 (ja) * | 1989-01-12 | 1997-11-12 | 鐘淵化学工業株式会社 | エノールシリルエーテル化合物の製造方法 |
| NZ234411A (en) * | 1989-07-18 | 1991-05-28 | Merck & Co Inc | Preparation of 2-diazo-3-silyloxy-3-butenoate esters |
| DE3934100A1 (de) * | 1989-10-12 | 1991-04-18 | Bayer Ag | Verfahren zur herstellung von 0-silylierten hydroxylverbindungen und ihre verwendung zur herstellung von estergruppen aufweisenden isocyanaten |
-
1996
- 1996-06-18 AR ARP960103190A patent/AR002507A1/es unknown
- 1996-06-24 CN CN96196325A patent/CN1193322A/zh active Pending
- 1996-06-24 CA CA002224439A patent/CA2224439A1/en not_active Abandoned
- 1996-06-24 EP EP96923404A patent/EP0836607A1/en not_active Withdrawn
- 1996-06-24 SK SK1765-97A patent/SK176597A3/sk unknown
- 1996-06-24 CZ CZ974190A patent/CZ419097A3/cs unknown
- 1996-06-24 KR KR1019970709722A patent/KR19990028406A/ko not_active Withdrawn
- 1996-06-24 WO PCT/US1996/010783 patent/WO1997001564A1/en not_active Ceased
- 1996-06-24 JP JP9504502A patent/JPH11513979A/ja active Pending
- 1996-06-24 AU AU63921/96A patent/AU696543B2/en not_active Ceased
- 1996-06-24 EA EA199800096A patent/EA199800096A1/ru unknown
- 1996-06-24 BR BR9609338A patent/BR9609338A/pt unknown
- 1996-06-24 HU HU9903016A patent/HUP9903016A3/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU6392196A (en) | 1997-01-30 |
| BR9609338A (pt) | 1999-05-11 |
| KR19990028406A (ko) | 1999-04-15 |
| HUP9903016A3 (en) | 2000-04-28 |
| EP0836607A1 (en) | 1998-04-22 |
| AR002507A1 (es) | 1998-03-25 |
| CN1193322A (zh) | 1998-09-16 |
| WO1997001564A1 (en) | 1997-01-16 |
| SK176597A3 (en) | 1998-07-08 |
| MX9800041A (es) | 1998-08-30 |
| JPH11513979A (ja) | 1999-11-30 |
| CA2224439A1 (en) | 1997-01-16 |
| CZ419097A3 (cs) | 1998-07-15 |
| AU696543B2 (en) | 1998-09-10 |
| HUP9903016A2 (hu) | 2000-03-28 |
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