DOP2024000166A - Antígenos tumorales, compuestos que comprenden los antígenos tumorales kras, tpx2 o aurka y usos de los mismos - Google Patents

Antígenos tumorales, compuestos que comprenden los antígenos tumorales kras, tpx2 o aurka y usos de los mismos

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Publication number
DOP2024000166A
DOP2024000166A DO2024000166A DO2024000166A DOP2024000166A DO P2024000166 A DOP2024000166 A DO P2024000166A DO 2024000166 A DO2024000166 A DO 2024000166A DO 2024000166 A DO2024000166 A DO 2024000166A DO P2024000166 A DOP2024000166 A DO P2024000166A
Authority
DO
Dominican Republic
Prior art keywords
tumour antigens
tpx2
aurka
kras
compounds
Prior art date
Application number
DO2024000166A
Other languages
English (en)
Spanish (es)
Inventor
Nolden Tobias
Belnoue Elodie
Derouazi Madiha
Adam Paul
Maria Rita Hofmann Irmgard
LEONHARDT Ralf
Lukowski Samuel
TRAPANI Francesca
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of DOP2024000166A publication Critical patent/DOP2024000166A/es

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4721—Lipocortins
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/10—Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
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  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Developmental Biology & Embryology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
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DO2024000166A 2022-03-16 2024-08-23 Antígenos tumorales, compuestos que comprenden los antígenos tumorales kras, tpx2 o aurka y usos de los mismos DOP2024000166A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP22162533 2022-03-16
EP22204783 2022-10-31
PCT/EP2023/056591 WO2023174998A1 (en) 2022-03-16 2023-03-15 Tumor antigens, compounds comprising the tumor antigens kras, tpx2 or aurka and uses thereof

Publications (1)

Publication Number Publication Date
DOP2024000166A true DOP2024000166A (es) 2024-09-30

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DO2024000166A DOP2024000166A (es) 2022-03-16 2024-08-23 Antígenos tumorales, compuestos que comprenden los antígenos tumorales kras, tpx2 o aurka y usos de los mismos

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Country Link
US (1) US20240033336A1 (https=)
EP (1) EP4493209A1 (https=)
JP (1) JP2025509648A (https=)
KR (1) KR20240161969A (https=)
AR (1) AR128799A1 (https=)
AU (1) AU2023235401A1 (https=)
CA (1) CA3252229A1 (https=)
CL (1) CL2024002708A1 (https=)
CO (1) CO2024012166A2 (https=)
CR (1) CR20240374A (https=)
DO (1) DOP2024000166A (https=)
IL (1) IL315096A (https=)
JO (1) JOP20240203A1 (https=)
MX (1) MX2024011238A (https=)
PE (1) PE20242221A1 (https=)
TW (1) TW202346363A (https=)
WO (1) WO2023174998A1 (https=)

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CN118256561A (zh) * 2024-03-22 2024-06-28 徐州医科大学 靶向双激酶aurka/cdk7的疫苗在治疗实体瘤中的应用

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ES2291071B1 (es) 2005-06-13 2009-03-16 Proyecto De Biomedicina Cima, S.L. Agentes y metodos basados en el uso del dominio eda de la fibronectina.
DE102008050860A1 (de) 2008-10-08 2010-04-15 Dorothee Von Laer LCMV-GP-VSV-Pseudotypvektoren und tumorinfiltrierende Virenproduzentenzellen zur Therapie von Tumoren
US20120237535A1 (en) 2009-09-11 2012-09-20 Proyecto De Biomedicina Cima, S.L. Therapeutic Compositions For The Treatment of HPV-Induced Diseases
WO2011101332A1 (en) 2010-02-16 2011-08-25 Proyecto De Biomedicina Cima, S.L. Compositions based on the fibronectin extracellular domain a for the treatment of melanoma
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DK3515476T3 (da) * 2016-09-21 2024-09-02 Amal Therapeutics Sa Fusion der omfatter et cellepenetrerende peptid, en multiepitop og en trl-peptidagnost til behandlingen af cancer
JP2020514321A (ja) * 2017-02-01 2020-05-21 モデルナティーエックス， インコーポレイテッド 活性化がん遺伝子変異ペプチドをコードする免疫調節治療ｍＲＮＡ組成物
AU2018247958A1 (en) * 2017-04-07 2019-10-10 Hookipa Biotech Gmbh Arenavirus particles to treat solid tumors

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WO2023174998A1 (en) 2023-09-21
MX2024011238A (es) 2024-09-19
JP2025509648A (ja) 2025-04-11
JOP20240203A1 (ar) 2024-09-15
PE20242221A1 (es) 2024-11-19
AU2023235401A1 (en) 2024-10-24
TW202346363A (zh) 2023-12-01
IL315096A (en) 2024-10-01
CO2024012166A2 (es) 2024-09-19
KR20240161969A (ko) 2024-11-13
AR128799A1 (es) 2024-06-12
EP4493209A1 (en) 2025-01-22
CA3252229A1 (en) 2023-09-21
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