DK66086A - Dihydropyridiner, fremgangsmaader til fremstilling heraf samt farmaceutiske midler indeholdende disse - Google Patents

Dihydropyridiner, fremgangsmaader til fremstilling heraf samt farmaceutiske midler indeholdende disse Download PDF

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Publication number
DK66086A
DK66086A DK66086A DK66086A DK66086A DK 66086 A DK66086 A DK 66086A DK 66086 A DK66086 A DK 66086A DK 66086 A DK66086 A DK 66086A DK 66086 A DK66086 A DK 66086A
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DK
Denmark
Prior art keywords
dihydropyridines
procedures
preparing
pharmaceutical agents
agents containing
Prior art date
Application number
DK66086A
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Danish (da)
English (en)
Other versions
DK66086D0 (da
Inventor
Rodney Brian Hargreaves
Bernard Joseph Mcloughlin
Stuart Dennett Mills
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Plc filed Critical Ici Plc
Publication of DK66086D0 publication Critical patent/DK66086D0/da
Publication of DK66086A publication Critical patent/DK66086A/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK66086A 1985-02-11 1986-02-11 Dihydropyridiner, fremgangsmaader til fremstilling heraf samt farmaceutiske midler indeholdende disse DK66086A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858503424A GB8503424D0 (en) 1985-02-11 1985-02-11 Heterocyclic derivatives

Publications (2)

Publication Number Publication Date
DK66086D0 DK66086D0 (da) 1986-02-11
DK66086A true DK66086A (da) 1986-08-12

Family

ID=10574269

Family Applications (1)

Application Number Title Priority Date Filing Date
DK66086A DK66086A (da) 1985-02-11 1986-02-11 Dihydropyridiner, fremgangsmaader til fremstilling heraf samt farmaceutiske midler indeholdende disse

Country Status (14)

Country Link
EP (1) EP0194750A1 (es)
JP (1) JPS61246162A (es)
AU (2) AU5397486A (es)
DK (1) DK66086A (es)
ES (1) ES8802026A1 (es)
FI (1) FI860622A (es)
GB (1) GB8503424D0 (es)
GR (1) GR860382B (es)
HU (1) HUT40416A (es)
IL (1) IL77849A0 (es)
NO (1) NO860471L (es)
PT (1) PT82021B (es)
WO (1) WO1986004581A1 (es)
ZA (1) ZA86997B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8403866D0 (en) * 1984-02-14 1984-03-21 Recordati Chem Pharm Diphenylalkylaminoalkyl esters
US4994476A (en) * 1984-10-31 1991-02-19 Bristol-Myers Company Dihydropyridin-3,5-dicarboxylates incorporating aryloxypropanolamine moieties
EP0254682A1 (de) * 1986-07-22 1988-01-27 Ciba-Geigy Ag Neue Phenoxyaliphatylphenylenoxyalkylester und -amide
US4782160A (en) * 1986-12-08 1988-11-01 Yamanouchi Pharmaceutical Co., Ltd. 1,4-dihydropyridine derivatives
US5468746A (en) * 1988-07-29 1995-11-21 Zambon Group S.P.A. Compounds active on the cardiovascular system
EP0352863A3 (en) * 1988-07-29 1990-08-22 ZAMBON GROUP S.p.A. 1,4-dihydropyridine dicarboxylic acid derivatives
IT1229118B (it) * 1988-07-29 1991-07-22 Simes Composti attivi sul sistema cardiovascolare che presentano sia la struttura dei beta-bloccanti sia una porzione calcio-antagonista
KR940005016B1 (ko) * 1990-11-30 1994-06-09 후지레비오 가부시끼가이샤 1,4-디히드로피리딘 유도체 및 그의 제조방법
DE4131346A1 (de) * 1991-09-20 1993-03-25 Bayer Ag Indolsulfonamid substituierte dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
JPH08502038A (ja) * 1992-07-28 1996-03-05 藤沢薬品工業株式会社 抗高血圧作用を有する1,4−ジヒドロピリジン誘導体およびその製造方法
NL1012886C1 (nl) 1999-08-23 2001-02-26 Rephartox 1,4-Dihydropyridine-5-carbonzuuresterderivaten en werkwijze voor de bereiding ervan.
JP2008521805A (ja) * 2004-11-30 2008-06-26 アーテシアン セラピューティクス, インコーポレイテッド β−アドレナリン作用性受容体およびホスホジエステラーゼに対する阻害活性を有する強心性化合物
CN101215258A (zh) * 2008-01-21 2008-07-09 中国药科大学 二氢吡啶类钙拮抗剂化合物及其制备方法与医药用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1409865A (en) * 1973-02-13 1975-10-15 Science Union & Cie Dihydropyridines derivatives their preparation and pharmaceu tical compositions containing them
JPS60156671A (ja) * 1984-01-25 1985-08-16 Yamanouchi Pharmaceut Co Ltd ジヒドロピリジン誘導体およびその製造法

Also Published As

Publication number Publication date
IL77849A0 (en) 1986-08-31
JPS61246162A (ja) 1986-11-01
ZA86997B (en) 1986-12-30
NO860471L (no) 1986-08-12
AU5397486A (en) 1986-08-26
ES8802026A1 (es) 1988-03-16
DK66086D0 (da) 1986-02-11
EP0194750A1 (en) 1986-09-17
ES551843A0 (es) 1988-03-16
GR860382B (en) 1986-05-29
FI860622A0 (fi) 1986-02-11
PT82021A (en) 1986-03-01
HUT40416A (en) 1986-12-28
GB8503424D0 (en) 1985-03-13
AU5339386A (en) 1986-08-14
WO1986004581A1 (en) 1986-08-14
FI860622A (fi) 1986-08-12
PT82021B (en) 1987-12-16

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