DK289888A - 2-substitueret-e-kondenserede oe1,2,4,aatriazolooe1,5-caapyrimidiner, farmaceutiske praeparater og anvendelser deraf - Google Patents

2-substitueret-e-kondenserede oe1,2,4,aatriazolooe1,5-caapyrimidiner, farmaceutiske praeparater og anvendelser deraf

Info

Publication number
DK289888A
DK289888A DK289888A DK289888A DK289888A DK 289888 A DK289888 A DK 289888A DK 289888 A DK289888 A DK 289888A DK 289888 A DK289888 A DK 289888A DK 289888 A DK289888 A DK 289888A
Authority
DK
Denmark
Prior art keywords
optionally substituted
caapyrimidines
condensed
substituted
applications
Prior art date
Application number
DK289888A
Other languages
Danish (da)
English (en)
Other versions
DK289888D0 (da
Inventor
John E Francis
Karl O Gelotte
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/020,055 external-priority patent/US4831013A/en
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK289888D0 publication Critical patent/DK289888D0/da
Publication of DK289888A publication Critical patent/DK289888A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Genetics & Genomics (AREA)
  • Psychiatry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Phenolic Resins Or Amino Resins (AREA)
DK289888A 1986-09-30 1988-05-27 2-substitueret-e-kondenserede oe1,2,4,aatriazolooe1,5-caapyrimidiner, farmaceutiske praeparater og anvendelser deraf DK289888A (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US91317386A 1986-09-30 1986-09-30
US07/020,055 US4831013A (en) 1986-03-20 1987-02-27 2-substituted-e-fused-[1,2,4]triazolo[1,5-c]pyrimidines, pharmaceutical compositions, and uses thereof
PCT/EP1987/000547 WO1988002370A1 (en) 1986-09-30 1987-09-25 2-substituted-e-fused-[1,2,4]triazolo[1,5-c]pyrimidines pharmaceutical compositions and uses thereof
CN89106168A CN1049120A (zh) 1986-09-30 1989-08-03 制取合成材料的方法

Publications (2)

Publication Number Publication Date
DK289888D0 DK289888D0 (da) 1988-05-27
DK289888A true DK289888A (da) 1988-05-27

Family

ID=36741346

Family Applications (1)

Application Number Title Priority Date Filing Date
DK289888A DK289888A (da) 1986-09-30 1988-05-27 2-substitueret-e-kondenserede oe1,2,4,aatriazolooe1,5-caapyrimidiner, farmaceutiske praeparater og anvendelser deraf

Country Status (13)

Country Link
EP (1) EP0263071B1 (no)
JP (1) JPH06104666B2 (no)
CN (1) CN1049120A (no)
AT (1) ATE79380T1 (no)
AU (1) AU612331B2 (no)
CA (1) CA1317590C (no)
DE (1) DE3781080T2 (no)
DK (1) DK289888A (no)
ES (1) ES2051772T3 (no)
FI (1) FI86727C (no)
GR (1) GR3006247T3 (no)
IE (1) IE59815B1 (no)
WO (1) WO1988002370A1 (no)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE64917B1 (en) * 1988-02-05 1995-09-20 Riker Laboratories Inc Triazolo[1,5-c]pyrimido[1,4]azines as bronchodilators
US5173492A (en) * 1989-09-14 1992-12-22 Kyowa Hakko Kogyo Co., Ltd. s-Triazolo(3,4-I)purine derivatives
CA2029651C (en) * 1989-11-17 2000-06-06 David D. Davey Tricyclic pteridinones and a process for their preparation
US5095015A (en) * 1990-07-24 1992-03-10 Neurogen Corporation Certain azacycloalkyl imidazopyrimidines; a new class of gaba brain receptor ligands
US5185446A (en) * 1990-09-04 1993-02-09 Neurogen Corporation Certain cycloalkyl imidazopyrimidines; a new class of gaba brainreceptor ligands
US5206222A (en) * 1991-05-22 1993-04-27 Vanderbilt University Methods for the reduction of myocardial reperfusion injury
GB9111130D0 (en) * 1991-05-23 1991-07-17 Ici Plc Azole derivatives
GB9111131D0 (en) * 1991-05-23 1991-07-17 Ici Plc Heterocyclic compounds
GB9125002D0 (en) * 1991-11-25 1992-01-22 Ici Plc Azole derivatives
IT1264901B1 (it) * 1993-06-29 1996-10-17 Schering Plough S P A Analoghi eterociclici di 1,2,4-triazolo(15-c)pirimidine ad attivita' antagonista per il recettore a2 dell'adenosina
EP0666079B1 (en) * 1993-07-27 2001-11-07 Kyowa Hakko Kogyo Co., Ltd. Remedy for parkinson's disease
US5955465A (en) * 1996-03-22 1999-09-21 Neurogen Corporation 1,2,4-triazolo 4,3-c!quinazolin-3-ones and 1,2,4-triazolo 4,3-c!quinazolin-3-thiones
US5677309A (en) * 1996-03-22 1997-10-14 Neurogen Corporation 1,2,4-triazolo 4,3-c! quinazolin-3-ones and 1,2,4-triazolo 4,3-c!quinazolin-3-thiones; a new class of GABA brain receptor ligands
CN1060698C (zh) * 1996-04-26 2001-01-17 清华大学 可完成多种快速原型制造工艺的多功能设备
CN1061279C (zh) * 1996-06-21 2001-01-31 李琎 制造铁铝或铁三铝金属间化合物零件的方法
ATE257156T1 (de) * 1997-03-24 2004-01-15 Kyowa Hakko Kogyo Kk (1,2,4)triazolo(1,5-c)pyrimidin-derivate
CA2326716C (en) * 1998-04-03 2006-12-12 Otsuka Pharmaceutical Factory, Inc. Triazolopurine derivative, pharmaceutical composition containing the derivative, adenosine a3 receptor ligand, and remedy for asthma
DE19826843A1 (de) * 1998-06-16 1999-12-23 Boehringer Ingelheim Pharma Neue Imidazotriazolopyrimidine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
US6448253B1 (en) * 1998-09-16 2002-09-10 King Pharmaceuticals Research And Development, Inc. Adenosine A3 receptor modulators
DE60010311T2 (de) 1999-09-28 2005-05-12 Otsuka Pharmaceutical Factory, Inc., Naruto Triazolpurin-derivate, medikamentzusammensetzungen, die diese enthalten und mittel, die affinität zum adenosin a3 rezeptor zeigen
IL160878A0 (en) * 2001-10-15 2004-08-31 Schering Corp Imidazo (4,3-e)-1,2,4-triazolo (1,5-c) pyrimidines as adenosine a2a receptor antagonists
US7196106B2 (en) 2002-11-05 2007-03-27 Merck & Co., Inc Cyanothiophene derivatives, compositions containing such compounds and methods of use
EA200501924A1 (ru) * 2003-06-10 2006-06-30 Киова Хакко Когио Ко., Лтд. Способ лечения тревожного расстройства
WO2014101113A1 (en) * 2012-12-28 2014-07-03 Merck Sharp & Dohme Corp. Piperazine-substituted 7-methoxy-[1,2,4]triazolo[1,5-c]quinazolin-5-amine compounds with a2a antagonist properties
GB2575490A (en) * 2018-07-12 2020-01-15 Recordati Ind Chimica E Farmaceutica Spa P2X3 receptor antagonists
US20210347778A1 (en) * 2018-08-30 2021-11-11 Tera Stone Co., Ltd Hydrazinopurine compound and triazolopurine compound for inhibiting xanthine oxidase
CA3135449A1 (en) * 2019-04-03 2020-10-08 Tera Stone Co., Ltd Triazolopyrimidines based on thymine nucleobase and methods for producing them
WO2022029063A1 (en) 2020-08-04 2022-02-10 Bayer Aktiengesellschaft Pyrido[1,2,4]triazolo[1,5-c]pyrimidin-5-amines
CN116380599B (zh) * 2023-06-06 2023-08-11 江苏省沙钢钢铁研究院有限公司 一种大尺寸非金属夹杂物的制备方法及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0181282A1 (de) * 1984-10-01 1986-05-14 Ciba-Geigy Ag Triazolochinazolinverbindungen
FR2576022B1 (fr) * 1985-01-11 1987-09-11 Rhone Poulenc Sante Nouveaux derives de la pristinamycine ii b, leur preparation et les compositions pharmaceutiques qui les contiennent
JPS62135475A (ja) * 1985-09-30 1987-06-18 チバ−ガイギ−　アクチエンゲゼルシヤフト ２−置換−ｅ−融合−〔１，２，４〕トリアゾロ−〔１，５−Ｃ〕ピリミジン
EP0217748B1 (en) * 1985-09-30 1991-02-06 Ciba-Geigy Ag 2-Substituted-e-fused-[1,2,4,]triazolo-[1,5-c]pyrimidines pharmaceutical compositions and uses thereof

Also Published As

Publication number Publication date
WO1988002370A1 (en) 1988-04-07
FI86727C (fi) 1992-10-12
CA1317590C (en) 1993-05-11
IE872615L (en) 1988-03-30
JPH01500996A (ja) 1989-04-06
EP0263071B1 (en) 1992-08-12
GR3006247T3 (no) 1993-06-21
DK289888D0 (da) 1988-05-27
FI882081A0 (fi) 1988-05-04
AU612331B2 (en) 1991-07-11
AU8027187A (en) 1988-04-21
DE3781080D1 (de) 1992-09-17
JPH06104666B2 (ja) 1994-12-21
ES2051772T3 (es) 1994-07-01
ATE79380T1 (de) 1992-08-15
EP0263071A1 (en) 1988-04-06
CN1049120A (zh) 1991-02-13
FI882081A (fi) 1988-05-04
IE59815B1 (en) 1994-04-06
FI86727B (fi) 1992-06-30
DE3781080T2 (de) 1992-12-24

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Legal Events

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AHS Application shelved for other reasons than non-payment