DK2733217T3 - Fremgangsmåde til påvisning af fugtskadede urinteststrimler - Google Patents

Fremgangsmåde til påvisning af fugtskadede urinteststrimler Download PDF

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Publication number
DK2733217T3
DK2733217T3 DK13005493.5T DK13005493T DK2733217T3 DK 2733217 T3 DK2733217 T3 DK 2733217T3 DK 13005493 T DK13005493 T DK 13005493T DK 2733217 T3 DK2733217 T3 DK 2733217T3
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Denmark
Prior art keywords
dyes
moisture
dye
reagents
reflectance
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DK13005493.5T
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English (en)
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Michael J Pugia
Chris T Zimmerle
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Siemens Healthcare Diagnostics Inc
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Publication of DK2733217T3 publication Critical patent/DK2733217T3/da

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/44—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G01N33/521—Single-layer analytical elements
    • G01N33/523—Single-layer analytical elements the element being adapted for a specific analyte
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Claims (7)

1. Anvendelse af et infrarødt farvestof som reference ved en fremgangsmåde til påvisning af et fugtskadet fugtfølsomt reagens, som er anbragt på en teststrimmel, hvor det fugtfølsomme reagens er baseret på proteolytiske substrater til påvisning af proteaseenzymer eller proteasehæmmere, hvilket fugtfølsomme reagens indbefatter et diazoniumsalt og udvikler farve eller en anden respons lige efter påføring af en prøve, hvilken farve eller anden respons måles og sammenlignes med det infrarøde referencefarvestof.
2. Anvendelse ifølge krav 1, hvor det infrarøde farvestof er kombineret med det fugtfølsomme reagens.
3. Anvendelse ifølge krav 1, hvor det infrarøde farvestof er placeret separat i forhold til det fugtfølsomme reagens.
4. Anvendelse ifølge et af kravene 1 -3, hvor det infrarøde farvestof er valgt fra gruppen bestående af phthalocyanin, naphthalocyanin, metalkompleksfarvestoffer, fortrinsvis dithiolen-metalkompleksfarvestoffer, polymethinfarvestoffer, cya-ninfarvestoffer, diphenylmethanfarvestoffer, triphenylmethanfarvestoffer, quinon-farvestoffer, azofarvestoffer, ladningsoverførselsfarvestoffer og ladningsresonansfarvestoffer.
5. Anvendelse ifølge et af kravene 1-4, hvor det infrarøde farvestof har en karakteristisk absorbans i det infrarøde område på fra ca. 700 til ca. 2500 nm.
6. Anvendelse ifølge et af kravene 1-5, hvor det fugtfølsomme reagens er et reagens til påvisning af leukocytter i urinprøver.
7. Anvendelse ifølge krav 6, hvor diazoniumsaltet er 1-diazo-2-naphthol-4-sul-fonsyre.
DK13005493.5T 2009-01-26 2010-01-14 Fremgangsmåde til påvisning af fugtskadede urinteststrimler DK2733217T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14727209P 2009-01-26 2009-01-26
EP20100733768 EP2382322B1 (en) 2009-01-26 2010-01-14 Device and method for detection of humidity-compromised urine test strips

Publications (1)

Publication Number Publication Date
DK2733217T3 true DK2733217T3 (da) 2016-08-01

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
DK16154774.0T DK3050974T3 (da) 2009-01-26 2010-01-14 Fremgangsmåde til konstatering af fugtkompromitterede urinprøvestrimler
DK13005493.5T DK2733217T3 (da) 2009-01-26 2010-01-14 Fremgangsmåde til påvisning af fugtskadede urinteststrimler

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DK16154774.0T DK3050974T3 (da) 2009-01-26 2010-01-14 Fremgangsmåde til konstatering af fugtkompromitterede urinprøvestrimler

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US (1) US9145576B2 (da)
EP (3) EP3050974B1 (da)
JP (1) JP5623430B2 (da)
KR (1) KR101659614B1 (da)
CN (2) CN103558189B (da)
AU (1) AU2010206939B2 (da)
BR (1) BRPI1006966B8 (da)
CA (1) CA2750538C (da)
DK (2) DK3050974T3 (da)
ES (3) ES2442877T3 (da)
MX (1) MX2011004308A (da)
PL (3) PL2733217T3 (da)
RU (1) RU2526805C2 (da)
WO (1) WO2010085413A1 (da)

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KR102185981B1 (ko) * 2018-02-28 2020-12-03 주식회사 엠디헬스케어 스트렙토코커스 속 세균 유래 나노소포 및 이의 용도
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Publication number Publication date
CN102292450A (zh) 2011-12-21
CN102292450B (zh) 2014-04-09
ES2573804T3 (es) 2016-06-10
BRPI1006966A2 (pt) 2016-04-12
KR20110115591A (ko) 2011-10-21
EP3050974A1 (en) 2016-08-03
PL2382322T3 (pl) 2014-05-30
EP2382322A1 (en) 2011-11-02
MX2011004308A (es) 2011-07-29
KR101659614B1 (ko) 2016-09-23
ES2707743T3 (es) 2019-04-04
AU2010206939A1 (en) 2010-07-29
AU2010206939B2 (en) 2014-08-21
CA2750538C (en) 2020-06-23
RU2011135567A (ru) 2013-03-10
JP2012515923A (ja) 2012-07-12
EP2733217B1 (en) 2016-04-06
EP2733217A1 (en) 2014-05-21
EP3050974B1 (en) 2018-10-24
BRPI1006966B8 (pt) 2021-07-27
DK3050974T3 (da) 2019-02-18
PL3050974T3 (pl) 2019-06-28
EP2382322A4 (en) 2012-07-18
WO2010085413A1 (en) 2010-07-29
PL2733217T3 (pl) 2016-10-31
ES2442877T3 (es) 2014-02-14
RU2526805C2 (ru) 2014-08-27
EP2382322B1 (en) 2013-12-18
CN103558189A (zh) 2014-02-05
US9145576B2 (en) 2015-09-29
US20110275104A1 (en) 2011-11-10
JP5623430B2 (ja) 2014-11-12
CA2750538A1 (en) 2010-07-29
BRPI1006966B1 (pt) 2020-12-08
CN103558189B (zh) 2017-04-19

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