DK1855677T3 - 3,11 B-CIS-dihydrotetrabanezin til behandling af skizofreni og andre psykoser - Google Patents

3,11 B-CIS-dihydrotetrabanezin til behandling af skizofreni og andre psykoser

Info

Publication number
DK1855677T3
DK1855677T3 DK06765238T DK06765238T DK1855677T3 DK 1855677 T3 DK1855677 T3 DK 1855677T3 DK 06765238 T DK06765238 T DK 06765238T DK 06765238 T DK06765238 T DK 06765238T DK 1855677 T3 DK1855677 T3 DK 1855677T3
Authority
DK
Denmark
Prior art keywords
psychoses
schizophrenia
cis
treatment
dihydrotetrabenzene
Prior art date
Application number
DK06765238T
Other languages
Danish (da)
English (en)
Inventor
Andrew John Duffield
Jean Elisabeth Yarrow
Original Assignee
Cambridge Lab Ireland Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0516167.4A external-priority patent/GB0516167D0/en
Priority claimed from GB0516790A external-priority patent/GB0516790D0/en
Application filed by Cambridge Lab Ireland Ltd filed Critical Cambridge Lab Ireland Ltd
Application granted granted Critical
Publication of DK1855677T3 publication Critical patent/DK1855677T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/473Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK06765238T 2005-08-06 2006-08-04 3,11 B-CIS-dihydrotetrabanezin til behandling af skizofreni og andre psykoser DK1855677T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0516167.4A GB0516167D0 (en) 2005-08-06 2005-08-06 Pharmaceutical compounds
GB0516790A GB0516790D0 (en) 2005-08-16 2005-08-16 Pharmaceutical compounds
PCT/GB2006/002936 WO2007017654A1 (fr) 2005-08-06 2006-08-04 3,11b cis-dihydrotetrabenazine permettant de traiter la schizophrenie et d'autres psychoses

Publications (1)

Publication Number Publication Date
DK1855677T3 true DK1855677T3 (da) 2009-02-09

Family

ID=37400949

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06765238T DK1855677T3 (da) 2005-08-06 2006-08-04 3,11 B-CIS-dihydrotetrabanezin til behandling af skizofreni og andre psykoser

Country Status (21)

Country Link
US (1) US20110257220A1 (fr)
EP (2) EP1855677B1 (fr)
JP (1) JP2009504622A (fr)
KR (1) KR20080033500A (fr)
AT (2) ATE534391T1 (fr)
AU (1) AU2006277753B2 (fr)
CA (1) CA2620960A1 (fr)
CY (1) CY1108843T1 (fr)
DE (1) DE602006004009D1 (fr)
DK (1) DK1855677T3 (fr)
ES (1) ES2318771T3 (fr)
HK (1) HK1111083A1 (fr)
HR (1) HRP20090074T3 (fr)
MX (1) MX2008001549A (fr)
NZ (1) NZ566011A (fr)
PL (1) PL1855677T3 (fr)
PT (1) PT1855677E (fr)
RS (1) RS50807B (fr)
RU (1) RU2407743C2 (fr)
SI (1) SI1855677T1 (fr)
WO (1) WO2007017654A1 (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2081929T3 (da) 2006-11-08 2013-04-15 Neurocrine Biosciences Inc Substituerede 3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11B-hexahydro-2H-pyrido[2,1-A]isoquinolin-2-ol-forbindelser og fremgangsmåder angående disse
US8008500B2 (en) 2007-06-08 2011-08-30 General Electric Company Intermediates useful for making tetrabenazine compounds
US8053578B2 (en) 2007-11-29 2011-11-08 General Electric Company Alpha-fluoroalkyl dihydrotetrabenazine imaging agents and probes
GB0810857D0 (en) * 2008-06-13 2008-07-23 Cambridge Lab Ireland Ltd Pharmaceutical compounds
GB2463451A (en) 2008-09-08 2010-03-17 Cambridge Lab 3, 11b cis-dihydrotetrabenazine compounds for use in the treatment of dementia
GB2463283A (en) * 2008-09-08 2010-03-10 Cambridge Lab 3,11b-cis-dihydrotetrabenazine for use in treating asthma
CN104744456A (zh) 2010-06-01 2015-07-01 奥斯拜客斯制药有限公司 Vmat2的苯并喹啉酮抑制剂
BR112013025151B1 (pt) 2011-04-01 2021-09-28 3M Innovative Properties Company Laminação retrorrefletiva
AU2015209330A1 (en) 2014-01-27 2016-07-28 Auspex Pharmaceuticals, Inc. Benzoquinoline inhibitors of vesicular monoamine transporter 2
NZ760790A (en) * 2014-02-07 2022-11-25 Neurocrine Biosciences Inc Pharmaceutical compositions comprising an antipsychotic drug and a vmat2 inhibitor and uses thereof
PT3368534T (pt) 2015-10-30 2021-03-09 Neurocrine Biosciences Inc Ditosilato de valbenazina e polimorfos do mesmo
US10160757B2 (en) 2015-12-23 2018-12-25 Neuroscrine Biosciences, Inc. Synthetic methods for preparation of (S)-(2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-yl 2-amino-3-methylbutanoate di(4-methylbenzenesulfonate)
TW201827051A (zh) * 2016-12-02 2018-08-01 美商神經性分泌生物科學公司 戊苯那嗪(valbenazine)於治療精神分裂症或情感性精神分裂症之用途
JP7199361B2 (ja) 2017-01-27 2023-01-05 ニューロクライン バイオサイエンシーズ,インコーポレイテッド 特定のvmat2インヒビターを投与するための方法
GB201705302D0 (en) * 2017-04-01 2017-05-17 Adeptio Pharmaceuticals Ltd Pharmaceutical compositions
GB201705303D0 (en) 2017-04-01 2017-05-17 Adeptio Pharmaceuticals Ltd Pharmaceutical compositions
GB201705304D0 (en) 2017-04-01 2017-05-17 Adeptio Pharmaceuticals Ltd Pharmaceutical compositions
GB201705306D0 (en) 2017-04-01 2017-05-17 Adeptio Pharmaceuticals Ltd Pharmaceutical compositions
US20200276184A1 (en) 2017-09-21 2020-09-03 Neurocrine Biosciences, Inc. High Dosage Valbenazine Formulation and Compositions, Methods, and Kits Related Thereto
US10993941B2 (en) 2017-10-10 2021-05-04 Neurocrine Biosciences, Inc. Methods for the administration of certain VMAT2 inhibitors
CN116492340A (zh) 2017-10-10 2023-07-28 纽罗克里生物科学有限公司 施用某些vmat2抑制剂的方法
GB201808464D0 (en) 2018-05-23 2018-07-11 Adeptio Pharmaceuticals Ltd Pharmaceutical compounds for use in treating huntington's disease
CA3104693A1 (fr) 2018-08-15 2020-02-20 Neurocrine Biosciences, Inc. Procedes d'administration de certains inhibiteurs de vmat2
US10940141B1 (en) 2019-08-23 2021-03-09 Neurocrine Biosciences, Inc. Methods for the administration of certain VMAT2 inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2843591A (en) 1958-07-15 Method for preparing same
US2830993A (en) 1958-04-15 Quinolizine derivatives
US6087376A (en) * 1997-02-05 2000-07-11 University Of Kentucky Research Foundation Use of lobeline compounds in the treatment of central nervous system diseases and pathologies
GB2410947B (en) * 2004-02-11 2008-09-17 Cambridge Lab Ltd Pharmaceutical compounds

Also Published As

Publication number Publication date
RU2407743C2 (ru) 2010-12-27
JP2009504622A (ja) 2009-02-05
CY1108843T1 (el) 2014-07-02
PL1855677T3 (pl) 2009-07-31
ATE534391T1 (de) 2011-12-15
ES2318771T3 (es) 2009-05-01
US20110257220A1 (en) 2011-10-20
AU2006277753A1 (en) 2007-02-15
EP2050451B1 (fr) 2011-11-23
EP1855677A1 (fr) 2007-11-21
EP2050451A1 (fr) 2009-04-22
HRP20090074T3 (en) 2009-04-30
HK1111083A1 (en) 2008-08-01
CA2620960A1 (fr) 2007-02-15
AU2006277753B2 (en) 2011-11-10
EP1855677B1 (fr) 2008-12-03
ATE415968T1 (de) 2008-12-15
SI1855677T1 (sl) 2009-04-30
RU2008108623A (ru) 2009-09-20
WO2007017654A1 (fr) 2007-02-15
PT1855677E (pt) 2009-01-13
DE602006004009D1 (de) 2009-01-15
KR20080033500A (ko) 2008-04-16
MX2008001549A (es) 2008-04-04
RS50807B (sr) 2010-08-31
NZ566011A (en) 2011-01-28

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