DK180022B1 - Method for producing a granular biomass which contains an oxidation-sensitive valuable substance. - Google Patents

Method for producing a granular biomass which contains an oxidation-sensitive valuable substance. Download PDF

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Publication number
DK180022B1
DK180022B1 DKPA201770205A DKPA201770205A DK180022B1 DK 180022 B1 DK180022 B1 DK 180022B1 DK PA201770205 A DKPA201770205 A DK PA201770205A DK PA201770205 A DKPA201770205 A DK PA201770205A DK 180022 B1 DK180022 B1 DK 180022B1
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weight
biomass
agglomeration
aurantiochytrium
cells
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DKPA201770205A
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Inventor
Eils Stefan
Diehl Michael
Priefert Horst
Rabe Christian
Dernedde Mathias
Schrickel Alexander
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Evonik Degussa Gmbh
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K40/00—Shaping or working-up of animal feeding-stuffs
    • A23K40/10—Shaping or working-up of animal feeding-stuffs by agglomeration; by granulation, e.g. making powders
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/005—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor after treatment of microbial biomass not covered by C12N1/02 - C12N1/08
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/12—Animal feeding-stuffs obtained by microbiological or biochemical processes by fermentation of natural products, e.g. of vegetable material, animal waste material or biomass
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/158—Fatty acids; Fats; Products containing oils or fats
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/163—Sugars; Polysaccharides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/80—Feeding-stuffs specially adapted for particular animals for aquatic animals, e.g. fish, crustaceans or molluscs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12—Fatty acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/20—Agglomerating; Granulating; Tabletting
    • A23P10/22—Agglomeration or granulation with pulverisation of solid particles, e.g. in a free-falling curtain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L31/00—Edible extracts or preparations of fungi; Preparation or treatment thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/80—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
    • Y02A40/81—Aquaculture, e.g. of fish
    • Y02A40/818—Alternative feeds for fish, e.g. in aquacultures

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Birds (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Sustainable Development (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Insects & Arthropods (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Botany (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Compounds Of Unknown Constitution (AREA)

Claims (17)

  1. PATENTKRAV
    1. Fremgangsmåde til fremstilling af en granuleret biomasse med en overvejende andel (>50%) af partikelstørrelser af 100 til 2500 mikrometer i diameter, hvilken biomasse omfatter et værdifuldt oxidationsfølsomt materiale, såsom et lipid, fortrinsvis en umættet fedtsyre, en flerumættet fedtsyre (PUFA) eller en højt umættet fedtsyre (HUFA), hvilken fremgangsmåde omfatter trinnene: tilvejebringelse af en partikelformig udgangsbiomasse behandlet uden forudgående cellenedbrydning, hvilken udgangsbiomasse har et resterende fugtighedsindhold af højst 10 vægt% og en overvejende andel (>50%) af partikelstørrelser af 20 til 100 mikrometer i diameter og udsættelse af udgangsbiomassen for en granuleringsmetode i nærvær af et agglomereringshjælpemiddel.
  2. 2. Fremgangsmåde ifølge krav 1,kendetegnet ved, at kulhydrater, især modificerede polysaccharider, anvendes som agglomereringshjælpemiddel.
  3. 3. Fremgangsmåde ifølge krav 2, kendetegnet ved, at guaran, arabisk gummi, guargummi, johannesbrødgummi, xanthangummi, agar, carrageenan, en maltodextrin, stivelse, især majsstivelse, tapiokastivelse eller kartoffelstivelse, cellulose eller derivater deraf, hemicellulose eller derivater deraf, alginsyre eller maltodextrin eller blandinger deraf anvendes som agglomereringshjælpemiddel.
  4. 4. Fremgangsmåde ifølge krav 3, kendetegnet ved, at modificeret cellulose, især carboxymethylcellulose og/eller hydroxypropylmethylcellulose, eller en maltodextrin eller blandinger deraf anvendes som agglomereringshjælpemiddel.
  5. 5. Fremgangsmåde ifølge et af de foregående krav, kendetegnet ved, at proteiner anvendes som agglomereringshjælpem iddel, især casein, gelatine, kollagen, hvedegluten eller blandinger deraf.
  6. 6. Fremgangsmåde ifølge et af de foregående krav, kendetegnet ved, at organiske polymerer anvendes som agglomereringshjælpemiddel, især lignosulfonat, polymethylolcarbamider, polyacrylsyrer eller polyvinylalkoholer eller blandinger deraf.
  7. 7. Fremgangsmåde ifølge et af de foregående krav, kendetegnet ved, at uorganiske stoffer anvendes som agglomereringshjælpemidler, især silikater, fortrinsvis bentonitter, hexametaphosphat eller blandinger deraf.
  8. 8. Fremgangsmåde ifølge et af de foregående krav, kendetegnet ved, at den partikelformige udgangsbiomasse er opnået ved spraytørring af en gæringsvæske indeholdende biomassen.
  9. 9. Fremgangsmåde ifølge et hvilket som helst af de foregående krav, kendetegnet ved, at biomassen omfatter celler af den taksonomiske gruppe Labyrinthulomycetes, især dem af familien Thraustochytriaceae, især fortrinsvis fra slægterne Thraustochytrium, Schizochytrium, Aurantiochytrium, Oblongichytrium eller Ulkenia, især fra Aurantiochytrium slægten.
  10. 10. Fremgangsmåde ifølge et af de foregående krav, kendetegnet ved, at det værdifulde oxidationsfølsomme materiale er PUFAs, fortrinsvis omega-3-fedtsyrer, især fortrinsvis DHA.
  11. 11. Granuleret biomasse fremstillet af fermenterede celler behandlet uden forudgående cellenedbrydning, hvilke celler omfatter et værdifuldt oxidationsfølsomt materiale valgt blandt en umættet fedtsyre, en flerumættet fedtsyre (PUFA) eller en højt umættet fedtsyre (HUFA), kendetegnet ved at den omfatter et agglomereringshjælpemiddel i en mængde af 0,05 til 6 vægt%, især 0,1 til 5 vægt%, især fortrinsvis 0,4 til 4 vægt%, og ved at den granulerede biomasse har en overvejende andel (>50 %) af partikelstørrelser af 100 til 2500 mikrometer i diameter.
  12. 12. Granuleret biomasse ifølge krav 11, kendetegnet ved, at agglomereringshjælpemidlet er et kulhydrat eller et modificeret kulhydrat, fortrinsvis en modificeret cellulose, især fortrinsvis carboxymethylcellulose eller hydroxypropylmethylcellulose, eller en maltodextrin eller blandinger deraf.
  13. 13. Granuleret biomasse ifølge krav 11 eller 12, kendetegnet ved, at den omfatter et hydrofilt eller hydrofobt silikat i en mængde af 0,05 til 6 vægt%, fortrinsvis 0,1 til 5 vægt%.
  14. 14. Granuleret biomasse ifølge et hvilket som helst af kravene 11 til
    13, kendetegnet ved, at mindst 80 vægt%, især mindst 90 vægt%, fortrinsvis mindst 95 vægt%, af partiklerne har en partikeldiameter (kornstørrelse) af fra 100 til 2000 μm, fortrinsvis 100 til 1500 μm, især fortrinsvis 100 til 1000 μm.
  15. 15. Granuleret biomasse ifølge et hvilket som helst af kravene 11 til
    14, kendetegnet ved, at den omfatter celler af den taksonomiske gruppe Labyrinthulomycetes, især dem af familien Thraustochytriaceae, især fortrinsvis fra slægterne Thraustochytrium, Schizochytrium, Aurantiochytrium eller Oblongichytrium, især fra slægten Aurantiochytrium, især fra arten Aurantiochytrium limacinum.
  16. 16. Granuleret biomasse ifølge et hvilket som helst af kravene 11 til
    15, kendetegnet ved, at det værdifulde oxidationsfølsomme materiale er PUFAs, fortrinsvis omega-3-fedtsyrer, især fortrinsvis DHA.
  17. 17. Foderstof eller levnedsmiddel omfattende en granuleret biomasse ifølge et hvilket som helst af kravene 11 til 16.
DKPA201770205A 2014-10-02 2015-09-22 Method for producing a granular biomass which contains an oxidation-sensitive valuable substance. DK180022B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14187460 2014-10-02
PCT/EP2015/071718 WO2016050560A1 (de) 2014-10-02 2015-09-22 Verfahren zur herstellung einer granulierten biomasse, die einen oxidationsempfindlichen wertstoff enthält

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DK201770205A1 DK201770205A1 (en) 2017-04-24
DK180022B1 true DK180022B1 (da) 2020-01-23

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US (1) US20170298318A1 (da)
EP (1) EP3200611A1 (da)
CN (1) CN106793802A (da)
BR (1) BR112017006835A2 (da)
CA (1) CA2958464A1 (da)
CL (1) CL2017000753A1 (da)
DK (1) DK180022B1 (da)
WO (1) WO2016050560A1 (da)

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CA2958464A1 (en) 2016-04-07
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BR112017006835A2 (pt) 2018-06-19
EP3200611A1 (de) 2017-08-09
CL2017000753A1 (es) 2017-12-15
CN106793802A (zh) 2017-05-31
US20170298318A1 (en) 2017-10-19

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