DK170139B1 - Anvendelse af dobbeltstrenget RNA til fremstilling af et middel til behandling af AIDS, fremgangsmåde til at gøre legemsvæsker eller blodlegemer resistente mod virusinfektion samt fremgangsmåde til fjernelse af vira - Google Patents
Anvendelse af dobbeltstrenget RNA til fremstilling af et middel til behandling af AIDS, fremgangsmåde til at gøre legemsvæsker eller blodlegemer resistente mod virusinfektion samt fremgangsmåde til fjernelse af vira Download PDFInfo
- Publication number
- DK170139B1 DK170139B1 DK405286A DK405286A DK170139B1 DK 170139 B1 DK170139 B1 DK 170139B1 DK 405286 A DK405286 A DK 405286A DK 405286 A DK405286 A DK 405286A DK 170139 B1 DK170139 B1 DK 170139B1
- Authority
- DK
- Denmark
- Prior art keywords
- dsrna
- cells
- aids
- interferon
- virus
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- External Artificial Organs (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US76949485A | 1985-08-26 | 1985-08-26 | |
US76949485 | 1985-08-26 | ||
US88636386A | 1986-07-17 | 1986-07-17 | |
US88636386 | 1986-07-17 |
Publications (3)
Publication Number | Publication Date |
---|---|
DK405286D0 DK405286D0 (da) | 1986-08-26 |
DK405286A DK405286A (da) | 1987-02-27 |
DK170139B1 true DK170139B1 (da) | 1995-06-06 |
Family
ID=27118178
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK405286A DK170139B1 (da) | 1985-08-26 | 1986-08-26 | Anvendelse af dobbeltstrenget RNA til fremstilling af et middel til behandling af AIDS, fremgangsmåde til at gøre legemsvæsker eller blodlegemer resistente mod virusinfektion samt fremgangsmåde til fjernelse af vira |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0213921B1 (zh) |
JP (1) | JPH0717510B2 (zh) |
CN (1) | CN1057231C (zh) |
CA (1) | CA1326450C (zh) |
DE (1) | DE3673288D1 (zh) |
DK (1) | DK170139B1 (zh) |
IE (1) | IE59277B1 (zh) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU728984B2 (en) * | 1987-03-03 | 2001-01-25 | Hem Research, Inc. | Syngeristic interplay of lymphokines and dsRNAs |
PH24467A (en) * | 1987-03-03 | 1990-07-18 | Hem Res Inc | Synergistics interplay of lymphokines and dsrnas |
PH30882A (en) * | 1987-03-03 | 1997-12-23 | Hem Res Inc | Activated Rnase L as a maker for viral infections. |
US4950652A (en) * | 1987-03-23 | 1990-08-21 | Hem Research, Inc. | dsRNAs for combination therapy in the treatment of viral diseases |
ZA881639B (en) * | 1987-03-23 | 1989-02-22 | Hem Res Inc | Treatment of human viral infection by dsrna combined with viral inhibitors |
AU728894B2 (en) * | 1987-07-17 | 2001-01-18 | Hem Research, Inc. | Double stranded RNA correction of aberrant metabolic pathways associated with uncontrolled tumor cell and virus growth cycles |
AU1820388A (en) * | 1987-07-17 | 1989-01-19 | Hem Research, Inc. | Double stranded rna correction of aberrant metabolic pathways associated with uncontrolled tumor cell and virus growth cycles |
AU1820588A (en) * | 1987-07-17 | 1989-01-19 | Hem Research, Inc. | Double-stranded rna correction of abnormalities in circulating immune complexes and monocyte function |
IE72103B1 (en) * | 1987-08-12 | 1997-03-12 | Hem Res Inc | Promotion of host defense by systemic dsRNA treatment |
US5683986A (en) * | 1987-08-12 | 1997-11-04 | Hemispherx Biopharma Inc. | Elaboration of host defense mediators into biological fluids by systemic dsRNA treatment |
IE66830B1 (en) * | 1987-08-12 | 1996-02-07 | Hem Res Inc | Topically active compositions of double-stranded RNAs |
US5593973A (en) * | 1987-09-04 | 1997-01-14 | Hemispherx Biopharma Inc. | Treatment of viral hepatitis with mismatched dsRNA |
DE3853755T2 (de) * | 1987-09-04 | 1995-12-14 | Hem Pharma Corp | Diagnose von Mangelzuständen doppelsträngiger RNS. |
US4963532A (en) * | 1987-11-25 | 1990-10-16 | Hem Research, Inc. | dsRNA-based prevention of viral escape |
PH25365A (en) * | 1987-12-23 | 1991-05-13 | Hem Research | Rhase l inhibitor as a marker for virus infections |
CA1320446C (en) * | 1988-06-20 | 1993-07-20 | William A. Carter | Modulation of lymphokine-resistant cellular states by dsrnas |
ES2066847T3 (es) * | 1988-07-07 | 1995-03-16 | Hem Pharma Corp | Diagnostico y tratamiento del sindrome de fatiga cronica. |
ZA908037B (en) * | 1989-10-11 | 1991-09-25 | Hem Res Inc | Protection from shock subsequent to injury by double-standed rnas |
ATE147630T1 (de) * | 1989-10-11 | 1997-02-15 | Hem Pharma Corp | Schutz gegen schock infolge einer schädigung durch doppelsträngige rna's |
GB9108085D0 (en) * | 1991-04-16 | 1991-06-05 | Scras | Complexes of polyadenylic acid with polyuridylic acid |
FR2766715B1 (fr) * | 1997-08-04 | 2001-02-16 | Scras | Produit comprenant au moins de l'arn double brin en association avec au moins un agent anti-viral pour une utilisation therapeutique simultanee, separee ou etalee dans le temps, dans le traitement d'une maladie virale |
FR2768345B1 (fr) * | 1997-09-17 | 2001-05-04 | Scras | Produit comprenant au moins un arn double brin en association avec au moins un agent anti-viral pour une utilisation therapeutique dans le traitement d'une maladie virale, notamment d'une hepatite virale |
FR2768344B1 (fr) * | 1997-08-26 | 2001-02-16 | Scras | Produit comprenant au moins un arn double brin en association avec au moins un agent anti-viral pour une utilisation therapeutique dans le traitement d'une maladie virale |
TW589189B (en) | 1997-08-04 | 2004-06-01 | Scras | Kit containing at least one double-stranded RNA combined with at least one anti-viral agent for therapeutic use in the treatment of a viral disease, notably of viral hepatitis |
US6506559B1 (en) | 1997-12-23 | 2003-01-14 | Carnegie Institute Of Washington | Genetic inhibition by double-stranded RNA |
AUPP249298A0 (en) | 1998-03-20 | 1998-04-23 | Ag-Gene Australia Limited | Synthetic genes and genetic constructs comprising same I |
EP1555317B1 (en) | 1998-03-20 | 2011-09-28 | Commonwealth Scientific And Industrial Research Organisation | Synthetic genes and genetic constructs comprising the same |
CA2361201A1 (en) | 1999-01-28 | 2000-08-03 | Medical College Of Georgia Research Institute, Inc. | Composition and method for in vivo and in vitro attenuation of gene expression using double stranded rna |
US6423885B1 (en) | 1999-08-13 | 2002-07-23 | Commonwealth Scientific And Industrial Research Organization (Csiro) | Methods for obtaining modified phenotypes in plant cells |
US20020132257A1 (en) | 2001-01-31 | 2002-09-19 | Tony Giordano | Use of post-transcriptional gene silencing for identifying nucleic acid sequences that modulate the function of a cell |
EP1957101A4 (en) * | 2005-12-07 | 2010-04-07 | Hemispherx Biopharma | DSRNA AS INFLUENZA VIRUS IMPFSTOFF ADJUVANTIES OR IMMUNOSTIMULATORS |
AU2013206335B2 (en) * | 2005-12-07 | 2017-05-04 | Hemispherx Biopharma, Inc. | dsRNAs as influenza virus vaccine adjuvants or immuno-stimulants |
CA3213217A1 (en) | 2021-04-28 | 2022-11-03 | Raphael Darteil | Strong potentiation of tlr3 agonists effects using fxr agonists as a combined treatment |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1412591A (en) * | 1971-11-30 | 1975-11-05 | Beecham Group Ltd | Antiviral ds rna and compositions thereof |
DE3380200D1 (en) * | 1982-09-16 | 1989-08-24 | William Alvin Carter | Anti-proliferative action of dsnras on tumor cells |
-
1986
- 1986-08-25 CA CA000516696A patent/CA1326450C/en not_active Expired - Lifetime
- 1986-08-26 DK DK405286A patent/DK170139B1/da not_active IP Right Cessation
- 1986-08-26 JP JP61198292A patent/JPH0717510B2/ja not_active Expired - Fee Related
- 1986-08-26 DE DE8686306582T patent/DE3673288D1/de not_active Expired - Fee Related
- 1986-08-26 IE IE227686A patent/IE59277B1/en not_active IP Right Cessation
- 1986-08-26 CN CN86105436A patent/CN1057231C/zh not_active Expired - Lifetime
- 1986-08-26 EP EP86306582A patent/EP0213921B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CN86105436A (zh) | 1987-09-16 |
EP0213921B1 (en) | 1990-08-08 |
EP0213921A3 (en) | 1988-01-07 |
JPS6277334A (ja) | 1987-04-09 |
EP0213921A2 (en) | 1987-03-11 |
DE3673288D1 (de) | 1990-09-13 |
IE862276L (en) | 1987-02-26 |
DK405286A (da) | 1987-02-27 |
CA1326450C (en) | 1994-01-25 |
CN1057231C (zh) | 2000-10-11 |
IE59277B1 (en) | 1994-02-09 |
DK405286D0 (da) | 1986-08-26 |
JPH0717510B2 (ja) | 1995-03-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B1 | Patent granted (law 1993) | ||
PBP | Patent lapsed |
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