DK165171C - Mikropartikel- og gasbobleholdigt ultralydskontrastmiddel samt udstyr og fremgangsmaade til dets fremstilling - Google Patents

Mikropartikel- og gasbobleholdigt ultralydskontrastmiddel samt udstyr og fremgangsmaade til dets fremstilling

Info

Publication number
DK165171C
DK165171C DK078984A DK78984A DK165171C DK 165171 C DK165171 C DK 165171C DK 078984 A DK078984 A DK 078984A DK 78984 A DK78984 A DK 78984A DK 165171 C DK165171 C DK 165171C
Authority
DK
Denmark
Prior art keywords
microparticle
procedure
manufacturing
equipment
controlling agent
Prior art date
Application number
DK078984A
Other languages
Danish (da)
English (en)
Other versions
DK78984D0 (da
DK165171B (da
DK78984A (da
Inventor
Juergen Hilmann
Lothar Lange
Ingfried Zimmermann
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of DK78984D0 publication Critical patent/DK78984D0/da
Publication of DK78984A publication Critical patent/DK78984A/da
Publication of DK165171B publication Critical patent/DK165171B/da
Application granted granted Critical
Publication of DK165171C publication Critical patent/DK165171C/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3925—Markers, e.g. radio-opaque or breast lesions markers ultrasonic

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Radiology & Medical Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acoustics & Sound (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fire-Detection Mechanisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
DK078984A 1983-04-15 1984-02-20 Mikropartikel- og gasbobleholdigt ultralydskontrastmiddel samt udstyr og fremgangsmaade til dets fremstilling DK165171C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3313946 1983-04-15
DE3313946A DE3313946A1 (de) 1983-04-15 1983-04-15 Mikropartikel und gasblaeschen enthaltende ultraschall-kontrastmittel

Publications (4)

Publication Number Publication Date
DK78984D0 DK78984D0 (da) 1984-02-20
DK78984A DK78984A (da) 1984-10-16
DK165171B DK165171B (da) 1992-10-19
DK165171C true DK165171C (da) 1993-03-01

Family

ID=6196665

Family Applications (1)

Application Number Title Priority Date Filing Date
DK078984A DK165171C (da) 1983-04-15 1984-02-20 Mikropartikel- og gasbobleholdigt ultralydskontrastmiddel samt udstyr og fremgangsmaade til dets fremstilling

Country Status (12)

Country Link
EP (1) EP0122624B1 (fr)
JP (1) JPS59205328A (fr)
AT (1) ATE36958T1 (fr)
AU (1) AU566928B2 (fr)
CA (1) CA1239092A (fr)
DE (2) DE3313946A1 (fr)
DK (1) DK165171C (fr)
FI (1) FI81264C (fr)
IE (1) IE57272B1 (fr)
NO (1) NO161356C (fr)
NZ (1) NZ207853A (fr)
ZA (1) ZA842801B (fr)

Families Citing this family (84)

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US5141738A (en) * 1983-04-15 1992-08-25 Schering Aktiengesellschaft Ultrasonic contrast medium comprising gas bubbles and solid lipophilic surfactant-containing microparticles and use thereof
DE3313947A1 (de) * 1983-04-15 1984-10-18 Schering AG, 1000 Berlin und 4709 Bergkamen Mikropartikel und gasblaeschen enthaltende ultraschall-kontrastmittel
DE3834705A1 (de) 1988-10-07 1990-04-12 Schering Ag Ultraschallkontrastmittel aus gasblaeschen und fettsaeure enthaltenden mikropartikeln
DK151366C (da) * 1984-12-05 1988-05-16 Tytex As Trusse samt fremgangsmaade til fremstilling heraf
DE3637926C1 (de) * 1986-11-05 1987-11-26 Schering Ag Ultraschall-Manometrieverfahren in einer Fluessigkeit mittels Mikroblaeschen
DE3741201A1 (de) 1987-12-02 1989-06-15 Schering Ag Ultraschallarbeitsverfahren und mittel zu dessen durchfuehrung
DE3741199A1 (de) * 1987-12-02 1989-08-17 Schering Ag Verwendung von ultraschallkontrastmitteln fuer die ultraschall-lithotripsie
US5425366A (en) * 1988-02-05 1995-06-20 Schering Aktiengesellschaft Ultrasonic contrast agents for color Doppler imaging
DE3803972A1 (de) * 1988-02-05 1989-08-10 Schering Ag Ultraschallkontrastmittel
ATE109663T1 (de) * 1988-02-05 1994-08-15 Schering Ag Ultraschallkontrastmittel, verfahren zu deren herstellung und deren verwendung als diagnostika und therapeutika.
DE3803971C2 (de) * 1988-02-05 1997-09-18 Schering Ag Ultraschallkontrastmittel
US5922304A (en) * 1989-12-22 1999-07-13 Imarx Pharmaceutical Corp. Gaseous precursor filled microspheres as magnetic resonance imaging contrast agents
USRE39146E1 (en) 1990-04-02 2006-06-27 Bracco International B.V. Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof
US7083778B2 (en) 1991-05-03 2006-08-01 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US6989141B2 (en) 1990-05-18 2006-01-24 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US5578292A (en) 1991-11-20 1996-11-26 Bracco International B.V. Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof
IN172208B (fr) * 1990-04-02 1993-05-01 Sint Sa
US5445813A (en) 1992-11-02 1995-08-29 Bracco International B.V. Stable microbubble suspensions as enhancement agents for ultrasound echography
US6613306B1 (en) 1990-04-02 2003-09-02 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US5137928A (en) * 1990-04-26 1992-08-11 Hoechst Aktiengesellschaft Ultrasonic contrast agents, processes for their preparation and the use thereof as diagnostic and therapeutic agents
US5190982A (en) * 1990-04-26 1993-03-02 Hoechst Aktiengesellschaft Ultrasonic contrast agents, processes for their preparation and the use thereof as diagnostic and therapeutic agents
US5205287A (en) * 1990-04-26 1993-04-27 Hoechst Aktiengesellschaft Ultrasonic contrast agents, processes for their preparation and the use thereof as diagnostic and therapeutic agents
AU636481B2 (en) * 1990-05-18 1993-04-29 Bracco International B.V. Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography
US5147631A (en) * 1991-04-30 1992-09-15 Du Pont Merck Pharmaceutical Company Porous inorganic ultrasound contrast agents
EP0586524B2 (fr) † 1991-06-03 2000-11-02 Nycomed Imaging As Ameliorations apportees a ou concernant des agents contrastants
JPH06511481A (ja) * 1991-07-05 1994-12-22 ユニバーシティ オブ ロチェスター 気泡を取り込む超微小非凝集多孔質粒子
JPH06510758A (ja) * 1991-07-05 1994-12-01 ニユコメド・イメージング・アクシエセルカペト 造影剤におけるまたは造影剤に関する改良
JPH0521183U (ja) * 1991-09-02 1993-03-19 サンデン株式会社 回転斜板式圧縮機
GB9200387D0 (en) * 1992-01-09 1992-02-26 Nycomed As Improvements in or relating to contrast agents
GB9200391D0 (en) * 1992-01-09 1992-02-26 Nycomed As Improvements in or relating to contrast agents
GB9200388D0 (en) * 1992-01-09 1992-02-26 Nycomed As Improvements in or relating to contrast agents
IL104084A (en) 1992-01-24 1996-09-12 Bracco Int Bv Sustainable aqueous suspensions of pressure-resistant and gas-filled blisters, their preparation, and contrast agents containing them
AU679295B2 (en) 1993-12-15 1997-06-26 Bracco Suisse S.A. Gas mixtures useful as ultrasound contrast media
DE4406474A1 (de) * 1994-02-23 1995-08-24 Schering Ag Gas enthaltende Mikropartikel, diese enthaltende Mittel, deren Verwendung in der Ultraschalldiagnostik, sowie Verfahren zur Herstellung der Partikel und Mittel
DE19510690A1 (de) 1995-03-14 1996-09-19 Schering Ag Polymere Nano- und/oder Mikropartikel, Verfahren zu deren Herstellung, sowie Verwendung in medizinischen Diagnostik und Therapie
DE19543077C2 (de) * 1995-11-13 1997-10-16 Schering Ag Verwendung von gashaltigen Metallkomplexen als Ultraschallkontrastmittel
DE19602930A1 (de) * 1996-01-18 1997-07-24 Schering Ag Poröse Matrices aus niedermolekularen Substanzen zur Genierung stabiler Gasblasensuspensionen, deren Verwendung als Ultraschallkontrastmittel sowie Verfahren zu deren Herstellung
DE19813174A1 (de) * 1998-03-25 1999-05-27 Schering Ag Mikropartikel aus Polymeren und mindestens einer gerüstbildenden Komponente und ihre Herstellung und Verwendung in der Ultraschalldiagnostik und zur ultraschallinduzierten Wirkstofffreisetzung
JP2002527410A (ja) 1998-10-12 2002-08-27 マリンクロッド・インコーポレイテッド 新規超音波造影剤
US6254852B1 (en) 1999-07-16 2001-07-03 Dupont Pharmaceuticals Company Porous inorganic targeted ultrasound contrast agents
EP2286843A3 (fr) 2000-06-02 2011-08-03 Bracco Suisse SA Composés pour le ciblage de cellules endothéliales
US6962071B2 (en) 2001-04-06 2005-11-08 Bracco Research S.A. Method for improved measurement of local physical parameters in a fluid-filled cavity
ATE520362T1 (de) 2001-12-03 2011-09-15 Ekos Corp Katheter mit mehreren ultraschall-abstrahlenden teilen
US7794693B2 (en) 2002-03-01 2010-09-14 Bracco International B.V. Targeting vector-phospholipid conjugates
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US7211240B2 (en) 2002-03-01 2007-05-01 Bracco International B.V. Multivalent constructs for therapeutic and diagnostic applications
US7261876B2 (en) 2002-03-01 2007-08-28 Bracco International Bv Multivalent constructs for therapeutic and diagnostic applications
EP2014310B8 (fr) 2002-03-01 2012-12-26 Dyax Corp. Peptides de liaison KDR et VEGF/KDR et leur utilisation pour le diagnostic et la thérapie
US8623822B2 (en) 2002-03-01 2014-01-07 Bracco Suisse Sa KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
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US7842377B2 (en) 2003-08-08 2010-11-30 Boston Scientific Scimed, Inc. Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
US8012454B2 (en) 2002-08-30 2011-09-06 Boston Scientific Scimed, Inc. Embolization
US7883490B2 (en) 2002-10-23 2011-02-08 Boston Scientific Scimed, Inc. Mixing and delivery of therapeutic compositions
ES2557286T3 (es) 2003-03-03 2016-01-25 Dyax Corp. Usos de péptidos que se unen específicamente al receptor del HGF (cMet)
US7976823B2 (en) 2003-08-29 2011-07-12 Boston Scientific Scimed, Inc. Ferromagnetic particles and methods
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US8425550B2 (en) 2004-12-01 2013-04-23 Boston Scientific Scimed, Inc. Embolic coils
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US9463426B2 (en) 2005-06-24 2016-10-11 Boston Scientific Scimed, Inc. Methods and systems for coating particles
US9011473B2 (en) 2005-09-07 2015-04-21 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
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US8518069B2 (en) 2005-09-07 2013-08-27 Cabochon Aesthetics, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US9358033B2 (en) 2005-09-07 2016-06-07 Ulthera, Inc. Fluid-jet dissection system and method for reducing the appearance of cellulite
US9486274B2 (en) 2005-09-07 2016-11-08 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
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CN104755108B (zh) 2012-10-25 2018-04-27 艾姆戈特株式会社 结合含有药物的纳米粒子的超声波造影剂及其制造方法
KR101595795B1 (ko) 2014-03-19 2016-02-22 (주)아이엠지티 약물을 함유한 나노입자가 결합된 이중-목적 paｔ／초음파 조영제 및 이의 제조방법
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US4277367A (en) * 1978-10-23 1981-07-07 Wisconsin Alumni Research Foundation Phantom material and method
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DE3141641A1 (de) * 1981-10-16 1983-04-28 Schering Ag, 1000 Berlin Und 4619 Bergkamen Ultraschall-kontrastmittel und dessen herstellung

Also Published As

Publication number Publication date
FI841462A0 (fi) 1984-04-12
NO841489L (no) 1984-10-16
EP0122624A2 (fr) 1984-10-24
AU566928B2 (en) 1987-11-05
NO161356B (no) 1989-05-02
DK78984D0 (da) 1984-02-20
ZA842801B (en) 1984-11-28
IE57272B1 (en) 1992-07-01
FI81264B (fi) 1990-06-29
NO161356C (no) 1989-08-09
ATE36958T1 (de) 1988-09-15
JPH0425934B2 (fr) 1992-05-06
EP0122624B1 (fr) 1988-09-07
FI841462A (fi) 1984-10-16
CA1239092A (fr) 1988-07-12
DK165171B (da) 1992-10-19
EP0122624A3 (en) 1986-11-20
DE3313946A1 (de) 1984-10-18
JPS59205328A (ja) 1984-11-20
FI81264C (fi) 1990-10-10
DE3473828D1 (en) 1988-10-13
AU2680584A (en) 1984-10-18
DK78984A (da) 1984-10-16
NZ207853A (en) 1988-01-08
IE840835L (en) 1984-10-15

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