DK1594963T3 - Proteaser - Google Patents
ProteaserInfo
- Publication number
- DK1594963T3 DK1594963T3 DK04737239T DK04737239T DK1594963T3 DK 1594963 T3 DK1594963 T3 DK 1594963T3 DK 04737239 T DK04737239 T DK 04737239T DK 04737239 T DK04737239 T DK 04737239T DK 1594963 T3 DK1594963 T3 DK 1594963T3
- Authority
- DK
- Denmark
- Prior art keywords
- proteases
- nocardiopsis
- relates
- animal feed
- copper
- Prior art date
Links
- 102000035195 Peptidases Human genes 0.000 title abstract 7
- 108091005804 Peptidases Proteins 0.000 title abstract 7
- 239000004365 Protease Substances 0.000 title abstract 6
- 239000010949 copper Substances 0.000 abstract 3
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 abstract 2
- 229910052802 copper Inorganic materials 0.000 abstract 2
- 241001134261 Brachysporiella gayana Species 0.000 abstract 1
- 241000223250 Metarhizium anisopliae Species 0.000 abstract 1
- 241000520851 Nocardiopsis alba Species 0.000 abstract 1
- 241000923014 Nocardiopsis dassonvillei subsp. dassonvillei Species 0.000 abstract 1
- 241000203616 Nocardiopsis prasina Species 0.000 abstract 1
- 241001221335 Nocardiopsis sp. Species 0.000 abstract 1
- 102000012479 Serine Proteases Human genes 0.000 abstract 1
- 108010022999 Serine Proteases Proteins 0.000 abstract 1
- 235000019730 animal feed additive Nutrition 0.000 abstract 1
- 239000003599 detergent Substances 0.000 abstract 1
- 235000019833 protease Nutrition 0.000 abstract 1
- 125000003607 serino group Chemical class [H]N([H])[C@]([H])(C(=O)[*])C(O[H])([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
- C12N2310/111—Antisense spanning the whole gene, or a large part of it
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Detergent Compositions (AREA)
- Fodder In General (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200300173 | 2003-02-07 | ||
DKPA200300426 | 2003-03-20 | ||
DKPA200300913 | 2003-06-19 | ||
DKPA200300915 | 2003-06-19 | ||
DKPA200300912 | 2003-06-19 | ||
DKPA200300914 | 2003-06-19 | ||
DKPA200301492 | 2003-10-10 | ||
DKPA200301493 | 2003-10-10 | ||
PCT/DK2004/000090 WO2004072221A2 (en) | 2003-02-07 | 2004-02-09 | Proteases |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1594963T3 true DK1594963T3 (da) | 2007-11-26 |
Family
ID=32873147
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK04737239T DK1594963T3 (da) | 2003-02-07 | 2004-02-09 | Proteaser |
Country Status (10)
Country | Link |
---|---|
US (3) | US7588926B2 (zh) |
EP (1) | EP1594963B1 (zh) |
CN (1) | CN1774504B (zh) |
AT (1) | ATE368105T1 (zh) |
AU (1) | AU2004211446B2 (zh) |
BR (1) | BRPI0407294B1 (zh) |
DE (1) | DE602004007766T2 (zh) |
DK (1) | DK1594963T3 (zh) |
ES (1) | ES2291883T3 (zh) |
WO (1) | WO2004072221A2 (zh) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6855548B2 (en) * | 2000-02-08 | 2005-02-15 | F. Hoffman-La Roche Ag | Use of acid-stable proteases in animal feed |
US6960462B2 (en) * | 2000-02-08 | 2005-11-01 | Dsm Ip Assets B.V | Use of acid-stable subtilisin proteases in animal feed |
ATE368105T1 (de) * | 2003-02-07 | 2007-08-15 | Novozymes As | Proteasen |
CN1836035B (zh) * | 2003-06-19 | 2013-03-20 | 诺维信公司 | 改进的蛋白酶及其制备方法 |
WO2004111222A1 (en) * | 2003-06-19 | 2004-12-23 | Novozymes A/S | Proteases |
PL1639105T5 (pl) * | 2003-06-19 | 2013-01-31 | Novozymes As | Proteazy |
WO2004111223A1 (en) * | 2003-06-19 | 2004-12-23 | Novozymes A/S | Proteases |
EP1639107B1 (en) | 2003-06-19 | 2013-08-14 | Novozymes A/S | Improved proteases and methods for producing them |
DE602004027376D1 (de) * | 2003-06-19 | 2010-07-08 | Novozymes As | Proteasen |
BRPI0414959A (pt) * | 2003-10-10 | 2006-11-07 | Novozymes As | variante de uma protease precursora, sequência de ácido nucleico isolado, construção de ácido nucleico, vetor de expressão e célula hospedeira recombinantes, métodos para produzir a variante de protease, para melhorar o valor nutricional de uma ração animal, e para tratar proteìnas, planta transgênica, ou parte da planta, animal transgênico, não humano, ou produtos, ou elementos deste, aditivo e composição de ração animal, uso da variante de protease e/ou da composição, protease, e, estrutura 3d |
WO2005123915A1 (en) * | 2004-06-21 | 2005-12-29 | Novozymes A/S | Stably maintained multiple copies of at least two orf in the same orientation |
ATE541034T1 (de) * | 2004-06-21 | 2012-01-15 | Novozymes As | Nocardiopsis-proteasen |
EP1786908B1 (en) * | 2004-08-18 | 2010-03-03 | Bayer CropScience AG | Plants with increased plastidic activity of r3 starch-phosphorylating enzyme |
HUE028879T2 (en) | 2006-07-13 | 2017-01-30 | Dsm Ip Assets Bv | Use of bacterial amylases in feed for bovine animals |
US20080031998A1 (en) | 2006-08-07 | 2008-02-07 | Novozymes A/S | Enzyme Granules for Animal Feed |
US9578891B2 (en) | 2006-08-07 | 2017-02-28 | Novozymes A/S | Enzyme granules for animal feed |
EP2089065B1 (en) * | 2006-10-27 | 2015-01-21 | E.I. Du Pont De Nemours And Company | Method for prion decontamination |
AU2007338014B2 (en) * | 2006-12-22 | 2013-10-24 | Novozymes A/S | Method for producing a yeast extract |
WO2009140481A1 (en) | 2008-05-14 | 2009-11-19 | Novozymes A/S | Liquid detergent compositions |
US20110081450A1 (en) * | 2008-06-03 | 2011-04-07 | Novozymes A/S | Method for Producing A Wheat Protein Hydrolysate |
MX2010014091A (es) * | 2008-06-20 | 2011-03-21 | Solae Llc | Composiciones de hidrolizado de proteinas estables en condiciones acidas. |
CN102325876A (zh) * | 2009-02-19 | 2012-01-18 | 诺维信公司 | 酿造方法 |
EP2413720B1 (en) * | 2009-04-02 | 2019-07-17 | Novozymes A/S | Process for making a milk-based protein hydrolysate |
US20140295027A1 (en) | 2011-08-19 | 2014-10-02 | Novozymes A/S | Polypeptides Having Protease Activity |
ES2628190T3 (es) | 2011-09-22 | 2017-08-02 | Novozymes A/S | Polipéptidos con actividad de proteasa y polinucleótidos que codifican los mismos |
CN104024408B (zh) | 2011-12-28 | 2019-04-19 | 诺维信公司 | 具有蛋白酶活性的多肽 |
EP2807254B1 (en) | 2012-01-26 | 2017-08-02 | Novozymes A/S | Use of polypeptides having protease activity in animal feed and detergents |
MX364390B (es) | 2012-06-20 | 2019-04-25 | Novozymes As | Uso de polipeptidos que tienen actividad proteasa en alimentos para animales y detergentes. |
DK2893012T3 (en) | 2012-09-05 | 2018-12-03 | Novozymes As | Polypeptides with protease activity |
AU2013326972B2 (en) * | 2012-10-03 | 2019-08-08 | Agrivida, Inc. | Intein-modified proteases, their production and industrial applications |
FR2998450A1 (fr) * | 2012-11-26 | 2014-05-30 | Dominique Hooreman | Utilisation d'un complexe enzymatique dans l'alimentation des animaux d'elevage |
MX363360B (es) | 2012-12-21 | 2019-03-21 | Novozymes As | Polipéptidos que poseen actividad proteasa y polinucleótidos que los codifican. |
WO2014122161A2 (en) | 2013-02-06 | 2014-08-14 | Novozymes A/S | Polypeptides having protease activity |
US10980249B2 (en) | 2014-06-27 | 2021-04-20 | Dsm Ip Assets B.V. | Method for improving the nutritional value of animal feed |
CN104293760A (zh) * | 2014-10-14 | 2015-01-21 | 夏盛(武汉)生物科技有限公司 | 一种多酶复合型抑泡剂及其在酒精发酵工业中的应用 |
WO2016071302A1 (en) | 2014-11-04 | 2016-05-12 | Novozymes A/S | Polypeptides having serine protease activity and polynucleotides encoding same and their application in animal feed |
TW201940778A (zh) | 2018-01-16 | 2019-10-16 | 日商花王股份有限公司 | 角質汙垢清潔劑、及角質汙垢分解能力之評估方法 |
CN113166231A (zh) * | 2018-10-10 | 2021-07-23 | 诺维信公司 | 胰凝乳蛋白酶抑制剂变体及其用途 |
CN110283880A (zh) * | 2019-08-08 | 2019-09-27 | 天津科技大学 | 一种测定蛋白酶活力的新方法 |
Family Cites Families (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3668448A (en) * | 1967-05-29 | 1972-06-06 | Enakichi Hayasaka | Homopole type ac generator |
GB1234445A (zh) * | 1967-10-03 | 1971-06-03 | ||
DE2004328C3 (de) | 1970-01-30 | 1979-10-18 | Nippon Kokan K.K., Tokio | Bodenkonstruktion für eine Gas-Flüssigkeits-Kontaktierkolonne |
US3823072A (en) * | 1970-02-19 | 1974-07-09 | M Hooreman | Analysis of proteolytic enzymes |
US3683069A (en) | 1970-02-19 | 1972-08-08 | Michel Hooreman | Enzymatic products which optimize the viscosity of mucuses and their applications |
US3663069A (en) * | 1970-10-07 | 1972-05-16 | Kelsey Hayes Co | Skid control system |
US3868448A (en) | 1973-12-07 | 1975-02-25 | Grace W R & Co | Method for bloat control |
US3966971A (en) * | 1975-01-02 | 1976-06-29 | Grain Processing Corporation | Separation of protein from vegetable sources |
US4073884A (en) * | 1976-09-27 | 1978-02-14 | W. R. Grace & Co. | Promotion of feed efficiency |
DE3149457A1 (de) * | 1981-12-14 | 1983-06-23 | Henkel KGaA, 4000 Düsseldorf | Verfahren zur herstellung saurer protease und diese bildende mutanten von pilzen der gattung aspergillus |
IE81141B1 (en) | 1983-06-24 | 2000-04-05 | Genencor Int | Procaryotic carbonyl hydrolases |
CA1295566C (en) | 1987-07-21 | 1992-02-11 | Robert T. Garvin | Characterization and structure of genes for protease a and protease b from streptomyces griseus |
FR2600340A1 (fr) * | 1986-06-20 | 1987-12-24 | Hooremam Michel | Procede de production d'un nouveau complexe proteolytique stimulant l'activite du pancreas et ses applications en zootechnie |
DK564086A (da) * | 1986-11-25 | 1988-06-17 | Novo Industri As | Enzymatisk detergent-additiv |
JPH02255081A (ja) | 1989-03-30 | 1990-10-15 | Snow Brand Milk Prod Co Ltd | プロテアーゼ生産菌、該菌体から産生したプロテアーゼ、及びその精製方法 |
DK316989D0 (da) | 1989-06-26 | 1989-06-26 | Novo Nordisk As | Enzymer |
ES2063340T3 (es) | 1990-01-11 | 1995-01-01 | Novo Nordisk As | Enzima bacteriolitica natural de una cepa de nocardiopsis, su produccion y uso. |
CA2063892A1 (en) | 1991-03-29 | 1992-09-30 | Susan A. Anderson | Alpha-lytic protease cleaning compositions |
ES2090481T3 (es) | 1991-05-01 | 1996-10-16 | Unilever Nv | Composiciones detergentes que contienen enzimas estabilizadas. |
KR100258460B1 (ko) | 1991-05-01 | 2000-06-01 | 한센 핀 베네드 | 안정화 효소 및 세제 조성물 |
US5646028A (en) * | 1991-06-18 | 1997-07-08 | The Clorox Company | Alkaline serine protease streptomyces griseus var. alkaliphus having enhanced stability against urea or guanidine |
US5811382A (en) * | 1991-12-20 | 1998-09-22 | Novo Nordisk A/S | Detergent compositions |
ES2173888T3 (es) | 1992-05-19 | 2002-11-01 | Shionogi & Co | Nueva proteasa. |
DK81193D0 (da) | 1993-07-06 | 1993-07-06 | Novo Nordisk As | Enzym |
CA2158752A1 (en) | 1994-02-14 | 1995-08-17 | Patrick S. Lee | Animal food palatability improving composition and process |
EP0756457B2 (en) | 1994-04-22 | 2008-10-08 | Novozymes A/S | A method for improving the solubility of vegetable proteins |
GB9416841D0 (en) | 1994-08-19 | 1994-10-12 | Finnfeeds Int Ltd | An enzyme feed additive and animal feed including it |
US5877403A (en) * | 1994-12-30 | 1999-03-02 | Seminis Vegetable Seeds, Inc. | Papaya ringspot virus protease gene |
DK1396A (zh) | 1996-01-09 | 1996-01-09 | Novo Nordisk As | |
US5705379A (en) * | 1996-10-23 | 1998-01-06 | Cornell Research Foundation, Inc. | Nucleotide sequences encoding a thermostable alkaline protease |
US6068630A (en) * | 1997-01-02 | 2000-05-30 | St. Francis Medical Technologies, Inc. | Spine distraction implant |
FI972521A (fi) | 1997-06-13 | 1998-12-14 | Cultor Oy | Menetelmä ravinnollisen tuotteen valmistamiseksi ja näin valmistettu tuote |
NZ330940A (en) | 1997-07-24 | 2000-02-28 | F | Production of consensus phytases from fungal origin using computer programmes |
US6835550B1 (en) | 1998-04-15 | 2004-12-28 | Genencor International, Inc. | Mutant proteins having lower allergenic response in humans and methods for constructing, identifying and producing such proteins |
US6855548B2 (en) * | 2000-02-08 | 2005-02-15 | F. Hoffman-La Roche Ag | Use of acid-stable proteases in animal feed |
US6960462B2 (en) * | 2000-02-08 | 2005-11-01 | Dsm Ip Assets B.V | Use of acid-stable subtilisin proteases in animal feed |
CN1293191C (zh) | 2000-02-08 | 2007-01-03 | Dsmip资产公司 | 酸-稳定性枯草蛋白酶在动物饲料中的用途 |
US7630836B2 (en) * | 2001-05-30 | 2009-12-08 | The Kitasato Institute | Polynucleotides |
JP4137526B2 (ja) | 2002-01-23 | 2008-08-20 | Toto株式会社 | ケラチナーゼおよびその製造法 |
JP4114046B2 (ja) | 2002-07-12 | 2008-07-09 | 川村通商株式会社 | 酵素脱毛処理剤および酵素脱毛法 |
JP4344950B2 (ja) | 2003-02-06 | 2009-10-14 | 大和化成株式会社 | 獣毛繊維の防縮加工法 |
ATE368105T1 (de) | 2003-02-07 | 2007-08-15 | Novozymes As | Proteasen |
WO2004072279A2 (en) | 2003-02-07 | 2004-08-26 | Novozymes A/S | Proteases |
WO2004111223A1 (en) | 2003-06-19 | 2004-12-23 | Novozymes A/S | Proteases |
PL1639105T5 (pl) | 2003-06-19 | 2013-01-31 | Novozymes As | Proteazy |
DE602004027376D1 (de) | 2003-06-19 | 2010-07-08 | Novozymes As | Proteasen |
US7208310B2 (en) * | 2003-06-19 | 2007-04-24 | Novozymes A/S | Proteases |
WO2004111222A1 (en) | 2003-06-19 | 2004-12-23 | Novozymes A/S | Proteases |
EP1639107B1 (en) * | 2003-06-19 | 2013-08-14 | Novozymes A/S | Improved proteases and methods for producing them |
CN1836035B (zh) * | 2003-06-19 | 2013-03-20 | 诺维信公司 | 改进的蛋白酶及其制备方法 |
US7935501B2 (en) * | 2003-09-11 | 2011-05-03 | Novozymes Pharma Biotec A/S | Recombinant production of antimicrobial peptides |
BRPI0414959A (pt) * | 2003-10-10 | 2006-11-07 | Novozymes As | variante de uma protease precursora, sequência de ácido nucleico isolado, construção de ácido nucleico, vetor de expressão e célula hospedeira recombinantes, métodos para produzir a variante de protease, para melhorar o valor nutricional de uma ração animal, e para tratar proteìnas, planta transgênica, ou parte da planta, animal transgênico, não humano, ou produtos, ou elementos deste, aditivo e composição de ração animal, uso da variante de protease e/ou da composição, protease, e, estrutura 3d |
ATE541034T1 (de) * | 2004-06-21 | 2012-01-15 | Novozymes As | Nocardiopsis-proteasen |
EP1766000A1 (en) * | 2004-06-21 | 2007-03-28 | Novozymes A/S | Improved methods of producing heterologous proteases |
US7618801B2 (en) * | 2007-10-30 | 2009-11-17 | Danison US Inc. | Streptomyces protease |
US20100093633A1 (en) * | 2008-10-10 | 2010-04-15 | Novozymes A/S | Polypeptides having antimicrobial activity |
EP2413720B1 (en) * | 2009-04-02 | 2019-07-17 | Novozymes A/S | Process for making a milk-based protein hydrolysate |
-
2004
- 2004-02-09 AT AT04737239T patent/ATE368105T1/de not_active IP Right Cessation
- 2004-02-09 DE DE602004007766T patent/DE602004007766T2/de not_active Expired - Lifetime
- 2004-02-09 CN CN2004800092012A patent/CN1774504B/zh not_active Expired - Fee Related
- 2004-02-09 ES ES04737239T patent/ES2291883T3/es not_active Expired - Lifetime
- 2004-02-09 WO PCT/DK2004/000090 patent/WO2004072221A2/en active IP Right Grant
- 2004-02-09 EP EP04737239A patent/EP1594963B1/en not_active Expired - Lifetime
- 2004-02-09 DK DK04737239T patent/DK1594963T3/da active
- 2004-02-09 US US10/544,861 patent/US7588926B2/en active Active
- 2004-02-09 BR BRPI0407294-4A patent/BRPI0407294B1/pt not_active IP Right Cessation
- 2004-02-09 AU AU2004211446A patent/AU2004211446B2/en not_active Ceased
-
2009
- 2009-05-15 US US12/466,470 patent/US7906310B2/en not_active Expired - Fee Related
-
2011
- 2011-01-27 US US13/014,974 patent/US20110124084A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20060147499A1 (en) | 2006-07-06 |
AU2004211446A1 (en) | 2004-08-26 |
US7588926B2 (en) | 2009-09-15 |
ES2291883T3 (es) | 2008-03-01 |
WO2004072221A2 (en) | 2004-08-26 |
US7906310B2 (en) | 2011-03-15 |
ATE368105T1 (de) | 2007-08-15 |
US20110124084A1 (en) | 2011-05-26 |
EP1594963A2 (en) | 2005-11-16 |
BRPI0407294A (pt) | 2006-02-07 |
US20090238922A1 (en) | 2009-09-24 |
DE602004007766T2 (de) | 2008-06-05 |
AU2004211446B2 (en) | 2009-05-28 |
CN1774504A (zh) | 2006-05-17 |
BRPI0407294B1 (pt) | 2017-06-13 |
DE602004007766D1 (de) | 2007-09-06 |
CN1774504B (zh) | 2013-04-17 |
WO2004072221A3 (en) | 2004-09-30 |
EP1594963B1 (en) | 2007-07-25 |
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