DK157785D0 - 1,5-benzothiazepinderivater og fremgangsmaade til deres fremstilling - Google Patents

1,5-benzothiazepinderivater og fremgangsmaade til deres fremstilling

Info

Publication number
DK157785D0
DK157785D0 DK157785A DK157785A DK157785D0 DK 157785 D0 DK157785 D0 DK 157785D0 DK 157785 A DK157785 A DK 157785A DK 157785 A DK157785 A DK 157785A DK 157785 D0 DK157785 D0 DK 157785D0
Authority
DK
Denmark
Prior art keywords
sup
hydrogen
procedures
preparation
benzothiazepine derivatives
Prior art date
Application number
DK157785A
Other languages
English (en)
Other versions
DK172257B1 (da
DK157785A (da
Inventor
Mikio Takeda
Tokuro Oh-Ishi
Hiromichi Nakajima
Taku Nagao
Original Assignee
Tanabe Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co filed Critical Tanabe Seiyaku Co
Publication of DK157785D0 publication Critical patent/DK157785D0/da
Publication of DK157785A publication Critical patent/DK157785A/da
Application granted granted Critical
Publication of DK172257B1 publication Critical patent/DK172257B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK157785A 1984-04-10 1985-04-09 1,5-benzothiazepinderivater og fremgangsmåde til deres fremstilling DK172257B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8409258 1984-04-10
GB8409258 1984-04-10

Publications (3)

Publication Number Publication Date
DK157785D0 true DK157785D0 (da) 1985-04-09
DK157785A DK157785A (da) 1985-10-11
DK172257B1 DK172257B1 (da) 1998-02-09

Family

ID=10559475

Family Applications (1)

Application Number Title Priority Date Filing Date
DK157785A DK172257B1 (da) 1984-04-10 1985-04-09 1,5-benzothiazepinderivater og fremgangsmåde til deres fremstilling

Country Status (12)

Country Link
US (1) US4585768A (da)
EP (1) EP0158339B1 (da)
JP (1) JPS60226866A (da)
KR (1) KR910005414B1 (da)
AT (1) ATE40126T1 (da)
AU (1) AU572978B2 (da)
CA (1) CA1218991A (da)
DE (1) DE3567650D1 (da)
DK (1) DK172257B1 (da)
ES (2) ES8705408A1 (da)
HU (1) HU191785B (da)
SU (2) SU1632372A3 (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2167063A (en) * 1984-11-17 1986-05-21 Tanabe Seiyaku Co 6 or 9-chloro-1, 5-benzothiazepine derivatives
JPS62161776A (ja) * 1986-01-07 1987-07-17 Tanabe Seiyaku Co Ltd １，５−ベンゾチアゼピン誘導体の製法
JPS63107925A (ja) * 1986-05-23 1988-05-12 Tanabe Seiyaku Co Ltd 動脈硬化症予防・治療剤
US4729994A (en) * 1986-08-20 1988-03-08 Mcneilab, Inc. Benzothiazepine vasodilators having aralkyl substitution
FR2624117B1 (fr) * 1987-12-08 1991-02-22 Synthelabo Derives de hydroxy-3 (methoxy-4 phenyl)-2 (methylamino-2 ethyl)-5 dihydro-2,3 5h-benzothiazepine-1,5 one-4, leur preparation et leur application en therapeutique
FR2630107B1 (fr) * 1988-04-19 1990-06-08 Synthelabo Procede de preparation du (+) - (2s,3s) (amino-2 phenyl)thio)-3 hydroxy-2 (methoxy-4 phenyl)-3 propionate de methyle
NL8801311A (nl) * 1988-05-20 1989-12-18 Stamicarbon Fenylglycidaatstereoisomeren, omzettingsprodukten daarvan met 2-nitrothiofenol en de bereiding van diltiazem.
IL91453A0 (en) * 1988-09-02 1990-04-29 Tanabe Seiyaku Co Preparation of optically active 3-phenyl-glycidic acid esters
FR2637285B1 (fr) * 1988-10-03 1991-04-12 Synthelabo Procede de preparation de derives de l'acide propionique et produits obtenus
US6521445B1 (en) * 1988-10-26 2003-02-18 Sepracor, Inc. Process for preparing optically active glycidate esters
US5274300A (en) 1988-10-26 1993-12-28 Sepracor, Inc. Enzymatic hydrolysis of glycidate esters in the presence of bisulfite anion
FR2642425A1 (fr) * 1989-01-30 1990-08-03 Sanofi Sa Procede de preparation de derives de benzothiazepine-1,5 one-4
JP2674232B2 (ja) * 1989-08-31 1997-11-12 田辺製薬株式会社 １，５―ベンゾチアゼピン誘導体
JPH088879B2 (ja) * 1989-09-13 1996-01-31 田辺製薬株式会社 光学活性３―フェニルグリシッド酸エステル類化合物の製法
US5250679A (en) * 1991-10-18 1993-10-05 Genentech, Inc. Nonpeptidyl platelet aggregation inhibitors having specificity for the GPIIb III.sub. receptor
US5565449A (en) * 1991-10-18 1996-10-15 Genentech, Inc. Nonpeptidyl integrin inhibitors having specificity for the GPIIb IIIa receptor
JP2643798B2 (ja) * 1992-10-23 1997-08-20 田辺製薬株式会社 末梢動脈血流増加剤
FR2704848B1 (fr) * 1993-05-03 1995-07-21 Prod Chim Auxil Synthese Précurseur liquide pour la production de revêtements d'oxyde d'étain dopé au fluor et procédé de revêtement correspondant.
US5580867A (en) * 1994-09-09 1996-12-03 Universite De Montreal Myocardial protection during ischemia and reperfusion

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3075967A (en) * 1961-06-12 1963-01-29 Olin Mathieson Benzothiazines
US3341519A (en) * 1965-04-28 1967-09-12 Squibb & Sons Inc Novel benzoxazines, benzothiazines, benzoxazepins and benzothiazepins
US3562257A (en) * 1967-10-28 1971-02-09 Tanabe Seiyaku Co Benzothiazepine derivatives
GB1236467A (en) * 1967-10-28 1971-06-23 Tanabe Seiyaku Co Benzothiazepine derivatives
JPS56156217A (en) * 1980-05-02 1981-12-02 Tanabe Seiyaku Co Ltd Inhibitor against blood platelet agglutination
JPS56156218A (en) * 1980-05-02 1981-12-02 Tanabe Seiyaku Co Ltd Inhibitor against blood platelet agglutination
US4567175A (en) * 1983-06-03 1986-01-28 Tanabe Seiyaku Co., Ltd. 8-Chloro-1,5-benzothiazepine derivatives
GB8316032D0 (en) * 1983-06-11 1983-07-13 Tanabe Seiyaku Co Benzothiazepine derivatives
CH665909A5 (fr) * 1985-05-15 1988-06-15 Matix Ind Sa Procede et dispositif de detection par ultrasons des defauts internes d'un rail de chemin de fer situes dans les bords du champignon de ce rail, utilisation du dispositif.
US5708066A (en) * 1995-03-01 1998-01-13 E. I. Du Pont De Nemours And Company Reaction curable composition and solid surface material

Also Published As

Publication number Publication date
HU191785B (en) 1987-04-28
ATE40126T1 (de) 1989-02-15
SU1632372A3 (ru) 1991-02-28
JPS60226866A (ja) 1985-11-12
JPH0374659B2 (da) 1991-11-27
SU1358784A3 (ru) 1987-12-07
AU572978B2 (en) 1988-05-19
ES557061A0 (es) 1988-01-01
HUT37411A (en) 1985-12-28
ES8705408A1 (es) 1987-05-01
KR910005414B1 (ko) 1991-07-29
EP0158339A3 (en) 1986-06-11
US4585768A (en) 1986-04-29
ES542125A0 (es) 1987-05-01
DK172257B1 (da) 1998-02-09
DK157785A (da) 1985-10-11
CA1218991A (en) 1987-03-10
EP0158339A2 (en) 1985-10-16
AU4039285A (en) 1985-10-17
KR850007248A (ko) 1985-12-02
DE3567650D1 (en) 1989-02-23
EP0158339B1 (en) 1989-01-18
ES8801230A1 (es) 1988-01-01

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DK157785D0 (da) 1,5-benzothiazepinderivater og fremgangsmaade til deres fremstilling
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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed
PBP Patent lapsed