DK1362855T3 - beta-lactam-forbindelser, en fremgangsmåde til fremstilling af disse forbindelser og serumkolesterolsænkende midler indeholdende disse forbindelser - Google Patents

beta-lactam-forbindelser, en fremgangsmåde til fremstilling af disse forbindelser og serumkolesterolsænkende midler indeholdende disse forbindelser

Info

Publication number
DK1362855T3
DK1362855T3 DK02703861T DK02703861T DK1362855T3 DK 1362855 T3 DK1362855 T3 DK 1362855T3 DK 02703861 T DK02703861 T DK 02703861T DK 02703861 T DK02703861 T DK 02703861T DK 1362855 T3 DK1362855 T3 DK 1362855T3
Authority
DK
Denmark
Prior art keywords
compounds
group
carbon atoms
chain
chem
Prior art date
Application number
DK02703861T
Other languages
Danish (da)
English (en)
Inventor
Hiroshi Tomiyama
Masayuki Yokota
Atsushi Noda
Akira Ohno
Original Assignee
Kotobuki Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kotobuki Pharmaceutical Co Ltd filed Critical Kotobuki Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DK1362855T3 publication Critical patent/DK1362855T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cephalosporin Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DK02703861T 2001-02-23 2002-02-20 beta-lactam-forbindelser, en fremgangsmåde til fremstilling af disse forbindelser og serumkolesterolsænkende midler indeholdende disse forbindelser DK1362855T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2001048202 2001-02-23
JP2001128031 2001-04-25
PCT/JP2002/001481 WO2002066464A1 (fr) 2001-02-23 2002-02-20 Composes de beta-lactame, leur procede de production et agents d'abaissement du taux de cholesterol contenant ces composes

Publications (1)

Publication Number Publication Date
DK1362855T3 true DK1362855T3 (da) 2008-01-28

Family

ID=26609978

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02703861T DK1362855T3 (da) 2001-02-23 2002-02-20 beta-lactam-forbindelser, en fremgangsmåde til fremstilling af disse forbindelser og serumkolesterolsænkende midler indeholdende disse forbindelser

Country Status (18)

Country Link
US (1) US7045515B2 (fr)
EP (1) EP1362855B1 (fr)
JP (1) JP4229701B2 (fr)
KR (1) KR100721639B1 (fr)
CN (1) CN1273467C (fr)
AT (1) ATE374769T1 (fr)
AU (1) AU2002237522B2 (fr)
BR (1) BRPI0206193B1 (fr)
CA (1) CA2438961C (fr)
DE (1) DE60222742T2 (fr)
DK (1) DK1362855T3 (fr)
ES (1) ES2294101T3 (fr)
HK (1) HK1060357A1 (fr)
MX (1) MXPA03005073A (fr)
PT (1) PT1362855E (fr)
RU (1) RU2301799C2 (fr)
TW (1) TWI291957B (fr)
WO (1) WO2002066464A1 (fr)

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AR060623A1 (es) 2006-04-27 2008-07-02 Astrazeneca Ab Compuestos derivados de 2-azetidinona y un metodo de preparacion
BRPI0715160A2 (pt) 2006-08-08 2013-06-11 Sanofi Aventis imidazolidina-2,4-dionas substituÍdas por arilamimoaril-alquil-, processo para preparÁ-las, medicamentos compeendendo estes compostos, e seu uso
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MX2009002922A (es) 2006-09-15 2009-04-01 Schering Corp Derivados de azetidina y azetidona utiles en el tratamiento del dolor y de trastornos del metabolismo lipidico.
JP2010503675A (ja) 2006-09-15 2010-02-04 シェーリング コーポレイション 疼痛、糖尿病および脂質代謝の障害の治療に有用なスピロ縮合アゼチジン誘導体
CA2663502A1 (fr) * 2006-09-15 2008-03-20 Schering Corporation Derives d'azetidinone et procedes d'utilisation de ceux-ci
WO2008085300A1 (fr) * 2006-12-20 2008-07-17 Merck & Co., Inc. Composé anti-hypercholestérolémique
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DE102007054497B3 (de) 2007-11-13 2009-07-23 Sanofi-Aventis Deutschland Gmbh Neue kristalline Diphenylazetidinonhydrate und Verfahren zu deren Herstellung
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WO2010068601A1 (fr) 2008-12-08 2010-06-17 Sanofi-Aventis Hydrate de fluoroglycoside hétéroaromatique cristallin, ses procédés de fabrication, ses procédés d'utilisation et compositions pharmaceutiques le contenant
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EP2379562A1 (fr) 2008-12-16 2011-10-26 Schering Corporation Dérivés de pyranone bicyclique comme agonistes du récepteur de l'acide nicotinique
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RU2012111354A (ru) 2009-08-26 2013-10-10 Санофи Новые кристаллические гидраты фторгликозидов, содержащие их фармацевтические препараты и их использование
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WO2012120055A1 (fr) 2011-03-08 2012-09-13 Sanofi Dérivés oxathiazine di- et tri-substitués, procédé pour leur préparation, utilisation en tant que médicament, agent pharmaceutique contenant ces dérivés et utilisation
EP2683702B1 (fr) 2011-03-08 2014-12-24 Sanofi Nouveaux dérivés de phényle-oxathiazine substitués, leur procédé de fabrication, médicament contenant ces liaisons et son utilisation
WO2012120058A1 (fr) 2011-03-08 2012-09-13 Sanofi Dérivés d'oxathiazine substitués par des groupes benzyle ou hétérométhylène, leur procédé de production, leur utilisation comme médicament ainsi que produits pharmaceutiques les contenant et leur utilisation
WO2012120054A1 (fr) 2011-03-08 2012-09-13 Sanofi Dérivés oxathiazine di- et tri-substitués, procédé pour leur préparation, utilisation en tant que médicament, agent pharmaceutique contenant ces dérivés et utilisation
US8901114B2 (en) 2011-03-08 2014-12-02 Sanofi Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof
EP2683704B1 (fr) 2011-03-08 2014-12-17 Sanofi Dérivés oxathiazine ramifiés, procédé pour leur préparation, utilisation en tant que médicament, agents pharmaceutiques contenant ces dérivés et leur utilisation
EP2683698B1 (fr) 2011-03-08 2017-10-04 Sanofi Dérivés benzyl-oxathiazine substitués avec adamantane ou noradamantane, médicaments contenant ces composés et leur utilisation
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CN113825839A (zh) 2019-03-20 2021-12-21 雷杰纳荣制药公司 用固醇调节元件结合蛋白切割激活蛋白(scap)抑制剂治疗脂质水平升高
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Also Published As

Publication number Publication date
CA2438961A1 (fr) 2002-08-29
AU2002237522B2 (en) 2007-08-02
EP1362855A1 (fr) 2003-11-19
US7045515B2 (en) 2006-05-16
BRPI0206193B1 (pt) 2016-05-24
EP1362855A4 (fr) 2005-02-23
CN1492865A (zh) 2004-04-28
HK1060357A1 (en) 2004-08-06
BR0206193A (pt) 2004-02-03
KR100721639B1 (ko) 2007-05-23
TWI291957B (en) 2008-01-01
CN1273467C (zh) 2006-09-06
DE60222742T2 (de) 2008-07-17
DE60222742D1 (de) 2007-11-15
ATE374769T1 (de) 2007-10-15
MXPA03005073A (es) 2003-09-05
EP1362855B1 (fr) 2007-10-03
JPWO2002066464A1 (ja) 2004-06-17
CA2438961C (fr) 2010-02-16
RU2301799C2 (ru) 2007-06-27
RU2003128424A (ru) 2005-01-27
JP4229701B2 (ja) 2009-02-25
KR20030076690A (ko) 2003-09-26
US20040063929A1 (en) 2004-04-01
WO2002066464A1 (fr) 2002-08-29
PT1362855E (pt) 2007-12-04
ES2294101T3 (es) 2008-04-01

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