DK1140942T3 - Prenyltransferaseinhibitorer - Google Patents

Prenyltransferaseinhibitorer

Info

Publication number
DK1140942T3
DK1140942T3 DK99968984T DK99968984T DK1140942T3 DK 1140942 T3 DK1140942 T3 DK 1140942T3 DK 99968984 T DK99968984 T DK 99968984T DK 99968984 T DK99968984 T DK 99968984T DK 1140942 T3 DK1140942 T3 DK 1140942T3
Authority
DK
Denmark
Prior art keywords
transferase inhibitors
prenyl transferase
chem
bond
prenyl
Prior art date
Application number
DK99968984T
Other languages
Danish (da)
English (en)
Inventor
Barry A Morgan
Thomas D Gordon
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Application granted granted Critical
Publication of DK1140942T3 publication Critical patent/DK1140942T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/14Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK99968984T 1998-12-31 1999-12-30 Prenyltransferaseinhibitorer DK1140942T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11430198P 1998-12-31 1998-12-31
US22442898A 1998-12-31 1998-12-31

Publications (1)

Publication Number Publication Date
DK1140942T3 true DK1140942T3 (da) 2004-05-24

Family

ID=26812031

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99968984T DK1140942T3 (da) 1998-12-31 1999-12-30 Prenyltransferaseinhibitorer

Country Status (14)

Country Link
US (2) US7361656B2 (pt)
EP (2) EP1382607B1 (pt)
AT (2) ATE440100T1 (pt)
AU (1) AU2717100A (pt)
CA (1) CA2356756A1 (pt)
CZ (1) CZ20012358A3 (pt)
DE (2) DE69941307D1 (pt)
DK (1) DK1140942T3 (pt)
ES (2) ES2328564T3 (pt)
HU (1) HUP0104708A3 (pt)
NO (1) NO321057B1 (pt)
PT (1) PT1140942E (pt)
RU (1) RU2241712C9 (pt)
WO (1) WO2000039130A2 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI283577B (en) * 1999-10-11 2007-07-11 Sod Conseils Rech Applic Pharmaceutical composition of imidazole derivatives acting as modulators of sodium channels and the use thereof
FR2812546B1 (fr) * 2000-08-01 2008-11-21 Sod Conseils Rech Applic Derives d'heterocycles a 5 chainons, leur preparation et leur application a titre de medicaments
DE60325744D1 (de) * 2002-09-27 2009-02-26 Sod Conseils Rech Applic Zubereitung zur behandlung des nasopharyngalen carcinom und verwendung derselben
CN101605779B (zh) * 2006-12-15 2013-11-20 百时美施贵宝公司 作为凝血因子xia抑制剂的芳基丙酰胺、芳基丙烯酰胺、芳基丙炔酰胺或芳基甲基脲类似物
TWI421252B (zh) 2009-07-09 2014-01-01 Irm Llc 用於治療寄生蟲疾病之化合物及組合物
EP2508511A1 (en) 2011-04-07 2012-10-10 Laboratoire Biodim Inhibitors of viral replication, their process of preparation and their therapeutical uses
PT2925745T (pt) * 2012-11-29 2018-08-08 Chemocentryx Inc Antagonistas de cxcr7
CN106317057B (zh) * 2015-07-02 2019-02-01 北京桦冠医药科技有限公司 具有咪唑并吡嗪类衍生物,其制备及其在医药上的应用
KR20190139291A (ko) 2017-04-24 2019-12-17 노파르티스 아게 2-아미노-l-(2-(4-플루오로페닐)-3-(4-플루오로페닐아미노)-8,8-디메틸-5,6-디하이드로이미다조[1,2-a]피라진-7(8h)-일)에타논 및 이의 조합물의 치료 요법

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5488109A (en) 1993-11-05 1996-01-30 Dowelanco 5-alkoxy[1,2,4]triazolo[1,5-c]pyrimidine-2(3H)--thione compounds and their use in the preparation of and 2-chlorosulfonyl-5-alkoxy[1,2,4]triazolo[1,5-c]-pyrimidine compounds
US5488189A (en) * 1993-12-14 1996-01-30 E. I. Du Pont De Nemours And Company Process for fluorinated propanes and pentanes
US6673927B2 (en) * 1996-02-16 2004-01-06 Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. Farnesyl transferase inhibitors
FR2780974B1 (fr) * 1998-07-08 2001-09-28 Sod Conseils Rech Applic Utilisation de derives d'imidazopyrazines pour preparer un medicament destine a traiter les pathologies qui resultent de la formation de la proteine g heterotrimetrique
UA74912C2 (en) * 2001-07-06 2006-02-15 Merck & Co Inc Beta-aminotetrahydroimidazo-(1,2-a)-pyrazines and tetratriazolo-(4,3-a)-pyrazines as inhibitors of dipeptylpeptidase for the treatment or prevention of diabetes

Also Published As

Publication number Publication date
NO20013281D0 (no) 2001-06-29
US7691859B2 (en) 2010-04-06
US20060142275A1 (en) 2006-06-29
WO2000039130A3 (en) 2000-11-02
ES2328564T3 (es) 2009-11-16
CA2356756A1 (en) 2000-07-06
EP1140942B1 (en) 2004-03-10
NO321057B1 (no) 2006-03-06
AU2717100A (en) 2000-07-31
DE69915514T2 (de) 2005-01-05
US20080176835A1 (en) 2008-07-24
CZ20012358A3 (cs) 2002-01-16
EP1382607B1 (en) 2009-08-19
WO2000039130A2 (en) 2000-07-06
HUP0104708A2 (hu) 2002-04-29
DE69915514D1 (de) 2004-04-15
ATE440100T1 (de) 2009-09-15
ES2215420T3 (es) 2004-10-01
RU2241712C9 (ru) 2006-04-20
EP1140942A2 (en) 2001-10-10
EP1382607A2 (en) 2004-01-21
US7361656B2 (en) 2008-04-22
DE69941307D1 (de) 2009-10-01
RU2241712C2 (ru) 2004-12-10
ATE261447T1 (de) 2004-03-15
HUP0104708A3 (en) 2004-05-28
PT1140942E (pt) 2004-05-31
NO20013281L (no) 2001-08-29
EP1382607A3 (en) 2004-06-30

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