DK1126874T5 - Multikomponent Meningococcus Vaccine - Google Patents

Multikomponent Meningococcus Vaccine

Info

Publication number
DK1126874T5
DK1126874T5 DK99954130T DK99954130T DK1126874T5 DK 1126874 T5 DK1126874 T5 DK 1126874T5 DK 99954130 T DK99954130 T DK 99954130T DK 99954130 T DK99954130 T DK 99954130T DK 1126874 T5 DK1126874 T5 DK 1126874T5
Authority
DK
Denmark
Prior art keywords
multicomponent
meningococcus vaccine
meningococcus
vaccine
outer membrane
Prior art date
Application number
DK99954130T
Other languages
Danish (da)
English (en)
Other versions
DK1126874T3 (da
DK1126874T4 (da
Inventor
Andrew Robinson
Andrew R Gorringe
Michael John Hudson
Karen M Reddin
Original Assignee
Health Prot Agency
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10841713&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1126874(T5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Health Prot Agency filed Critical Health Prot Agency
Publication of DK1126874T3 publication Critical patent/DK1126874T3/da
Application granted granted Critical
Publication of DK1126874T4 publication Critical patent/DK1126874T4/da
Publication of DK1126874T5 publication Critical patent/DK1126874T5/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK99954130T 1998-11-02 1999-11-02 Multikomponent Meningococcus Vaccine DK1126874T5 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9823978.3A GB9823978D0 (en) 1998-11-02 1998-11-02 Multicomponent meningococcal vaccine
PCT/GB1999/003626 WO2000025811A2 (en) 1998-11-02 1999-11-02 Multicomponent meningococcal vaccine

Publications (3)

Publication Number Publication Date
DK1126874T3 DK1126874T3 (da) 2003-09-29
DK1126874T4 DK1126874T4 (da) 2008-10-13
DK1126874T5 true DK1126874T5 (da) 2008-12-01

Family

ID=10841713

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99954130T DK1126874T5 (da) 1998-11-02 1999-11-02 Multikomponent Meningococcus Vaccine

Country Status (13)

Country Link
US (2) US6821521B1 (de)
EP (3) EP2248535A1 (de)
JP (2) JP2002528515A (de)
AT (1) ATE242640T1 (de)
AU (1) AU760858B2 (de)
BR (1) BR9914946A (de)
CA (1) CA2349331A1 (de)
DE (1) DE69908805T3 (de)
DK (1) DK1126874T5 (de)
ES (1) ES2197688T5 (de)
GB (1) GB9823978D0 (de)
PT (1) PT1126874E (de)
WO (1) WO2000025811A2 (de)

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US20030215469A1 (en) * 1998-11-02 2003-11-20 Microbiological Research Authority Multicomponent meningococcal vaccine
US10967045B2 (en) 1998-11-02 2021-04-06 Secretary of State for Health and Social Care Multicomponent meningococcal vaccine
US7081244B2 (en) 1999-02-22 2006-07-25 Health Protection Agency Neisserial vaccine compositions and methods
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CN102580072A (zh) 1999-05-19 2012-07-18 诺华疫苗和诊断有限公司 组合式奈瑟球菌组合物
AU784518B2 (en) 2000-01-17 2006-04-27 Glaxosmithkline Biologicals S.A. Outer membrane vesicle (OMV) vaccine comprising N. meningitidis serogroup B outer membrane proteins
AU2001280883A1 (en) 2000-07-27 2002-02-13 The Children's Hospital & Research Center At Oakland Vaccines for broad spectrum protection against diseases caused by neisseria meningitidis
GB0130123D0 (en) * 2001-12-17 2002-02-06 Microbiological Res Agency Outer membrane vesicle vaccine and its preparation
WO2004014419A1 (en) * 2002-08-02 2004-02-19 Glaxosmithkline Biologicals S.A. Vaccine composition comprising transferrin binding protein and hsf from gram negative bacteria
GB0220194D0 (en) 2002-08-30 2002-10-09 Chiron Spa Improved vesicles
HUE031886T2 (en) 2002-10-11 2017-08-28 Glaxosmithkline Biologicals Sa Polypeptide vaccines for extensive protection against hypervirulent meningococcal lines
AU2003288660A1 (en) 2002-11-15 2004-06-15 Chiron Srl Unexpected surface proteins in neisseria meningitidis
GB0227346D0 (en) 2002-11-22 2002-12-31 Chiron Spa 741
CA3042073C (en) 2003-01-30 2022-09-13 Novartis Vaccines And Diagnostics S.R.L. Injectable vaccines against multiple meningococcal serogroups
GB0323103D0 (en) 2003-10-02 2003-11-05 Chiron Srl De-acetylated saccharides
CU23377A1 (es) * 2003-11-04 2009-05-28 Ct De Ingenieria Genetica Y Biotecnologia Metodo para la incorporacion de antigenos en vesiculas de membrana externa de bacterias y formulaciones resultantes
GB0424092D0 (en) 2004-10-29 2004-12-01 Chiron Srl Immunogenic bacterial vesicles with outer membrane proteins
PL2682126T3 (pl) 2005-01-27 2017-07-31 Children's Hospital & Research Center At Oakland Szczepionki pęcherzykowe oparte na GNA1870 dla szerokiego spektrum ochrony przeciwko chorobom spowodowanym przez Neisseria meningitidis
GB0524066D0 (en) 2005-11-25 2006-01-04 Chiron Srl 741 ii
US7853431B2 (en) 2006-09-29 2010-12-14 Fisher-Rosemount Systems, Inc. On-line monitoring and diagnostics of a process using multivariate statistical analysis
US7378713B2 (en) * 2006-10-25 2008-05-27 Taiwan Semiconductor Manufacturing Co., Ltd. Semiconductor devices with dual-metal gate structures and fabrication methods thereof
GB0700562D0 (en) 2007-01-11 2007-02-21 Novartis Vaccines & Diagnostic Modified Saccharides
DK2200642T3 (da) 2007-10-19 2012-07-16 Novartis Ag Meningococvaccinepræparater
BRPI0907843A2 (pt) 2008-02-21 2015-08-04 Novartis Ag Polipeptídeos de fhbp menigocócicos
ES2546213T3 (es) 2008-03-03 2015-09-21 Novartis Ag Compuestos y composiciones como moduladores de la actividad de TLR
RU2477145C2 (ru) * 2008-05-30 2013-03-10 ДЗЕ Ю.Эс.Эй., ЭС РЕПРЕЗЕНТЕД БАЙ ДЗЕ СЕКРЕТАРИ ОФ ДЗЕ АРМИ, ОН БЕХАФ ОФ УОЛТЕР РИД АРМИ Мультивалентная вакцина из нативных везикул наружной мембраны менингококков, способы ее получения и применения
GB0822634D0 (en) 2008-12-11 2009-01-21 Novartis Ag Meningitis vaccines
BRPI0923006A2 (pt) 2008-12-17 2016-03-08 Novartis Ag vacinas meningococicas incluindo receptor de hemoglobina
EP2429658B1 (de) * 2009-05-14 2016-04-20 Sanofi Pasteur Verfahren zur Adjuvierung des Lipopolysaccharids (LPS) von gram-negativen Bakterien
AU2010247255A1 (en) * 2009-05-14 2012-01-12 Sanofi Pasteur Meningococcal vaccine based on lipooligosaccharide (LOS) and Neisseria meningitidis protein
CN102762226A (zh) 2009-06-10 2012-10-31 诺华有限公司 含苯并萘啶的疫苗
WO2011024072A2 (en) 2009-08-27 2011-03-03 Novartis Ag Hybrid polypeptides including meningococcal fhbp sequences
NZ598459A (en) 2009-08-27 2014-03-28 Novartis Ag Adjuvant comprising aluminium, oligonucleotide and polycation
JO3257B1 (ar) 2009-09-02 2018-09-16 Novartis Ag مركبات وتركيبات كمعدلات لفاعلية tlr
DK2459216T3 (da) 2009-09-02 2013-12-09 Novartis Ag Immunogene sammensætninger omfattende tlr-aktivitetsmodulatorer
GB0916557D0 (en) 2009-09-21 2009-10-28 Health Prot Agency Commensal neisserial stress protein complexes
WO2011039631A2 (en) 2009-09-30 2011-04-07 Novartis Ag Expression of meningococcal fhbp polypeptides
JP5960055B2 (ja) 2009-10-27 2016-08-02 ノバルティス アーゲー 改変髄膜炎菌ｆＨＢＰポリペプチド
WO2011057148A1 (en) 2009-11-05 2011-05-12 Irm Llc Compounds and compositions as tlr-7 activity modulators
SG10201501980SA (en) 2009-12-15 2015-05-28 Novartis Ag Homogeneous suspension of immunopotentiating compounds and uses thereof
WO2011110635A1 (en) 2010-03-10 2011-09-15 Glaxosmithkline Biologicals S.A. Immunogenic composition
MX2012010609A (es) 2010-03-18 2012-10-03 Novartis Ag Vacunas adyuvadas para meningococos serogrupo b.
US8808703B2 (en) 2010-03-23 2014-08-19 Tom Yao-Hsiang Wu Compounds (cystein based lipopeptides) and compositions as TLR2 agonists used for treating infections, inflammations, respiratory diseases etc
WO2012032498A2 (en) 2010-09-10 2012-03-15 Novartis Ag Developments in meningococcal outer membrane vesicles
US20130259948A1 (en) 2010-09-21 2013-10-03 National Institute Of Immunology Spray dried powder formulation for vaccines entrapping alum and the antigen in biodegradable polymer particles
EP2707009A1 (de) 2011-05-12 2014-03-19 Novartis AG Antipyretika zur verbesserung der verträglichkeit von impfstoffen auf vesikelbasis
GB201110980D0 (en) 2011-06-28 2011-08-10 Health Prot Agency Neisserial compositions and expression constructs
CN104114706A (zh) 2012-02-02 2014-10-22 诺华股份有限公司 用于脑膜炎球菌中增加的蛋白表达的启动子
CA2875391A1 (en) 2012-07-27 2014-01-30 Institut National De La Sante Et De La Recherche Medicale Cd147 as receptor for pilus-mediated adhesion of meningococci to vascular endothelia
BR112015005056A2 (pt) 2012-09-06 2017-11-21 Novartis Ag vacinas de combinação com sorogrupo b meningococcus e d/t/p
EP3782643A1 (de) 2014-02-28 2021-02-24 GlaxoSmithKline Biologicals SA Modifizierte meningokokken-fhbp-polypeptide
JP7008900B2 (ja) * 2015-06-02 2022-02-10 イントラヴァック ビー．ブイ． グラム陰性外膜小胞における抗原の表面提示

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US4707543A (en) * 1985-09-17 1987-11-17 The United States Of America As Represented By The Secretary Of The Army Process for the preparation of detoxified polysaccharide-outer membrane protein complexes, and their use as antibacterial vaccines
JPH01125328A (ja) 1987-07-30 1989-05-17 Centro Natl De Biopreparados 髄膜炎菌ワクチン
US7118757B1 (en) * 1988-12-19 2006-10-10 Wyeth Holdings Corporation Meningococcal class 1 outer-membrane protein vaccine
JP3436756B2 (ja) * 1988-12-19 2003-08-18 アメリカン・サイアナミド・カンパニー 髄膜炎菌のクラスｉの外膜タンパク質のワクチン
US5292869A (en) * 1989-04-27 1994-03-08 The Board Of Governors Of The University Method for isolating and purifying transferrin and lactoferrin receptor proteins from bacteria and the preparation of vaccines containing the same
FR2682041B1 (fr) 1991-10-03 1994-01-14 Pasteur Merieux Serums Vaccins Vaccin contre les infections a neisseria meningitidis.
NL9201716A (nl) * 1992-10-02 1994-05-02 Nederlanden Staat Buitenmembraanvesikel dat voorzien is van een groep polypeptiden welke ten minste de immuunwerking van aan membraan gebonden buitenmembraaneiwitten (OMP's) hebben, werkwijze ter bereiding ervan alsmede een vaccin dat een dergelijk buitenmembraanvesikel omvat.
US6287574B1 (en) * 1995-03-17 2001-09-11 Biochem Pharma Inc. Proteinase K resistant surface protein of neisseria meningitidis
US6180111B1 (en) 1995-05-18 2001-01-30 University Of Maryland Vaccine delivery system
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GB9711964D0 (en) 1997-06-09 1997-08-06 Medical Res Council Live attenuated vaccines
US6451317B1 (en) * 1997-07-17 2002-09-17 Baxter International Inc. Immunogenic conjugates comprising a Group B meningococcal porin and an H influenzae polysaccharide
US10967045B2 (en) * 1998-11-02 2021-04-06 Secretary of State for Health and Social Care Multicomponent meningococcal vaccine
GB9823978D0 (en) * 1998-11-02 1998-12-30 Microbiological Res Authority Multicomponent meningococcal vaccine
CN102580072A (zh) * 1999-05-19 2012-07-18 诺华疫苗和诊断有限公司 组合式奈瑟球菌组合物
GB9918319D0 (en) 1999-08-03 1999-10-06 Smithkline Beecham Biolog Vaccine composition
AU784518B2 (en) * 2000-01-17 2006-04-27 Glaxosmithkline Biologicals S.A. Outer membrane vesicle (OMV) vaccine comprising N. meningitidis serogroup B outer membrane proteins
AU2001280883A1 (en) * 2000-07-27 2002-02-13 The Children's Hospital & Research Center At Oakland Vaccines for broad spectrum protection against diseases caused by neisseria meningitidis
GB0130123D0 (en) * 2001-12-17 2002-02-06 Microbiological Res Agency Outer membrane vesicle vaccine and its preparation
WO2004014419A1 (en) * 2002-08-02 2004-02-19 Glaxosmithkline Biologicals S.A. Vaccine composition comprising transferrin binding protein and hsf from gram negative bacteria
AU2003288660A1 (en) * 2002-11-15 2004-06-15 Chiron Srl Unexpected surface proteins in neisseria meningitidis
GB0227346D0 (en) * 2002-11-22 2002-12-31 Chiron Spa 741
WO2009038889A1 (en) * 2007-08-02 2009-03-26 Children's Hospital And Research Center At Oakland Fhbp- and lpxl1-based vesicle vaccines for broad spectrum protection against diseases caused by neisseria meningitidis

Also Published As

Publication number Publication date
DE69908805T3 (de) 2008-12-24
EP1297844A2 (de) 2003-04-02
WO2000025811A3 (en) 2000-10-05
ES2197688T5 (es) 2008-12-16
US6821521B1 (en) 2004-11-23
WO2000025811A2 (en) 2000-05-11
BR9914946A (pt) 2001-07-10
ATE242640T1 (de) 2003-06-15
EP1126874B2 (de) 2008-06-25
EP1126874A2 (de) 2001-08-29
EP2248535A1 (de) 2010-11-10
EP1126874B1 (de) 2003-06-11
DK1126874T3 (da) 2003-09-29
JP2012025774A (ja) 2012-02-09
ES2197688T3 (es) 2004-01-01
DE69908805T2 (de) 2004-05-19
DK1126874T4 (da) 2008-10-13
US20090148469A1 (en) 2009-06-11
DE69908805D1 (de) 2003-07-17
JP2002528515A (ja) 2002-09-03
AU1056900A (en) 2000-05-22
CA2349331A1 (en) 2000-05-11
AU760858B2 (en) 2003-05-22
PT1126874E (pt) 2003-10-31
EP1297844A3 (de) 2004-01-14
GB9823978D0 (en) 1998-12-30

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