DK1038525T3 - Stabiliseret farmaceutisk præparat af tetrahydropyrrolo[1,2-a]pyrazin-4-spiro-3'-pyrrolidin - Google Patents

Stabiliseret farmaceutisk præparat af tetrahydropyrrolo[1,2-a]pyrazin-4-spiro-3'-pyrrolidin

Info

Publication number
DK1038525T3
DK1038525T3 DK98947882T DK98947882T DK1038525T3 DK 1038525 T3 DK1038525 T3 DK 1038525T3 DK 98947882 T DK98947882 T DK 98947882T DK 98947882 T DK98947882 T DK 98947882T DK 1038525 T3 DK1038525 T3 DK 1038525T3
Authority
DK
Denmark
Prior art keywords
acid
tetrahydropyrrolo
spiro
pyrrolidine
pyrazine
Prior art date
Application number
DK98947882T
Other languages
Danish (da)
English (en)
Inventor
Kazuyoshi Ogasawara
Yoshimi Shirai
Hiroshi Fujioka
Mamoru Ohashi
Original Assignee
Dainippon Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co filed Critical Dainippon Pharmaceutical Co
Application granted granted Critical
Publication of DK1038525T3 publication Critical patent/DK1038525T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/499—Spiro-condensed pyrazines or piperazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK98947882T 1997-10-20 1998-10-15 Stabiliseret farmaceutisk præparat af tetrahydropyrrolo[1,2-a]pyrazin-4-spiro-3'-pyrrolidin DK1038525T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP30663497 1997-10-20

Publications (1)

Publication Number Publication Date
DK1038525T3 true DK1038525T3 (da) 2004-08-02

Family

ID=17959466

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98947882T DK1038525T3 (da) 1997-10-20 1998-10-15 Stabiliseret farmaceutisk præparat af tetrahydropyrrolo[1,2-a]pyrazin-4-spiro-3'-pyrrolidin

Country Status (13)

Country Link
US (1) US6297244B1 (de)
EP (1) EP1038525B1 (de)
JP (1) JP3995414B2 (de)
KR (1) KR100571613B1 (de)
CN (1) CN1152686C (de)
AT (1) ATE270552T1 (de)
AU (1) AU9461898A (de)
DE (1) DE69824971T2 (de)
DK (1) DK1038525T3 (de)
ES (1) ES2224436T3 (de)
HK (1) HK1029921A1 (de)
PT (1) PT1038525E (de)
WO (1) WO1999020276A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR200001056T2 (tr) * 1997-10-20 2000-09-21 Dainippon Pharmaceutical Co., Ltd. Hızlı çözülen farmasötik terkipler.
CA2459172C (en) 2001-08-08 2011-07-05 Takeda Chemical Industries, Ltd. Bicyclic compound, production and use thereof
ZA200409537B (en) 2003-01-31 2006-10-25 Yamanouchi Pharma Co Ltd Stable solid medicinal composition for oral administration
AU2003236156A1 (en) * 2003-04-24 2005-01-04 Shin-Jen Shiao Pharmaceutical compositions used for immune disease treatment and improvement
WO2007022345A2 (en) * 2005-08-17 2007-02-22 Fleming And Company, Pharmaceuticals Vitamin b12 nasal spray and method of use
EP2327406A4 (de) * 2008-08-14 2014-04-09 Kyorin Seiyaku Kk Stabilisierte pharmazeutische zusammensetzung
WO2014186581A1 (en) * 2013-05-15 2014-11-20 Tobira Therapeutics, Inc. Cenicriviroc compositions and methods of making and using the same
WO2016039422A1 (ja) 2014-09-11 2016-03-17 大日本住友製薬株式会社 点眼用懸濁製剤
US11147811B2 (en) 2016-03-10 2021-10-19 Sumitomo Dainippon Pharma Co., Ltd. Composition comprising fine particle and process thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202450B (de) * 1991-06-26 1993-03-21 Dainippon Pharmaceutical Co
JP3158128B2 (ja) * 1992-12-25 2001-04-23 大日本製薬株式会社 コハク酸イミド誘導体
JPH08176105A (ja) * 1994-12-27 1996-07-09 Dainippon Pharmaceut Co Ltd ２−カルボキシコハク酸イミド誘導体

Also Published As

Publication number Publication date
ES2224436T3 (es) 2005-03-01
AU9461898A (en) 1999-05-10
KR20010015780A (ko) 2001-02-26
CN1152686C (zh) 2004-06-09
PT1038525E (pt) 2004-11-30
CN1282247A (zh) 2001-01-31
DE69824971T2 (de) 2004-12-23
EP1038525B1 (de) 2004-07-07
DE69824971D1 (de) 2004-08-12
JP3995414B2 (ja) 2007-10-24
EP1038525A1 (de) 2000-09-27
WO1999020276A1 (fr) 1999-04-29
EP1038525A4 (de) 2003-03-26
US6297244B1 (en) 2001-10-02
KR100571613B1 (ko) 2006-04-17
ATE270552T1 (de) 2004-07-15
HK1029921A1 (en) 2001-04-20

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