DK1023263T3 - Nye vitamin D analoger - Google Patents
Nye vitamin D analogerInfo
- Publication number
- DK1023263T3 DK1023263T3 DK98947397T DK98947397T DK1023263T3 DK 1023263 T3 DK1023263 T3 DK 1023263T3 DK 98947397 T DK98947397 T DK 98947397T DK 98947397 T DK98947397 T DK 98947397T DK 1023263 T3 DK1023263 T3 DK 1023263T3
- Authority
- DK
- Denmark
- Prior art keywords
- carbon atom
- hydroxy
- hydrogen
- groups
- hydrocarbylene
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Obesity (AREA)
- Transplantation (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9721156.9A GB9721156D0 (en) | 1997-10-06 | 1997-10-06 | Novel vitamin d analogues |
PCT/DK1998/000423 WO1999018070A1 (en) | 1997-10-06 | 1998-10-02 | Novel vitamin d analogues |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1023263T3 true DK1023263T3 (da) | 2002-12-02 |
Family
ID=10820110
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK98947397T DK1023263T3 (da) | 1997-10-06 | 1998-10-02 | Nye vitamin D analoger |
Country Status (20)
Country | Link |
---|---|
US (1) | US6399797B1 (ko) |
EP (1) | EP1023263B1 (ko) |
JP (1) | JP2001519327A (ko) |
KR (1) | KR20010030966A (ko) |
CN (1) | CN1140509C (ko) |
AT (1) | ATE219053T1 (ko) |
AU (1) | AU740457B2 (ko) |
CA (1) | CA2304152A1 (ko) |
CZ (1) | CZ295955B6 (ko) |
DE (1) | DE69806035T2 (ko) |
DK (1) | DK1023263T3 (ko) |
ES (1) | ES2175784T3 (ko) |
GB (1) | GB9721156D0 (ko) |
HK (1) | HK1031868A1 (ko) |
HU (1) | HUP0004226A3 (ko) |
NZ (1) | NZ503344A (ko) |
PL (1) | PL193060B1 (ko) |
PT (1) | PT1023263E (ko) |
RU (1) | RU2196132C2 (ko) |
WO (1) | WO1999018070A1 (ko) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2003528833A (ja) * | 2000-03-27 | 2003-09-30 | ウイスコンシン アラムナイ リサーチ フオンデーシヨン | 腎移植体安定化用のビタミンd化合物 |
US7351869B2 (en) * | 2002-11-18 | 2008-04-01 | Teva Pharmaceutical Industries Ltd | Crystallization method for purification of calcipotriene |
AU2005303773A1 (en) | 2004-11-12 | 2006-05-18 | Bioxell Spa | Combined use of vitamin D derivatives and anti-proliferative agents for treating bladder cancer |
EP1828114B1 (en) * | 2004-11-22 | 2010-04-21 | Wisconsin Alumni Research Foundation | 17,20(e)-dehydro vitamin d analogs and their uses |
US8193169B2 (en) * | 2006-04-06 | 2012-06-05 | Wisconsin Alumni Research Foundation | (20R)-2α-methyl-19,26,2-trinor-vitamin D analogs |
CN101505725A (zh) * | 2006-08-29 | 2009-08-12 | 特瓦制药工业有限公司 | 包含含维生素D的化合物和皮质类固醇化合物的具有低pH相容性的稳定的药理学活性组合物 |
US7648974B1 (en) * | 2008-07-10 | 2010-01-19 | Wisconsin Alumni Research Foundation | 19-nor-vitamin D analogs with 3,2-dihydrofuran ring |
US8399439B2 (en) * | 2008-07-10 | 2013-03-19 | Wisconsin Alumni Research Foundation | 2-methylene-19,26-dinor-(20S,22E,25R)-vitamin D analogs |
US7879829B2 (en) * | 2008-07-10 | 2011-02-01 | Wisconsin Alumni Research Foundation | 19-nor-vitamin D analogs with 1,2-dihydrofuran ring |
US7888339B2 (en) * | 2008-07-10 | 2011-02-15 | Wisconsin Alumni Research Foundation | 2-methylene-20(21)-dehydro-19-nor-vitamin D analogs |
US8222236B2 (en) * | 2008-07-10 | 2012-07-17 | Wisconsin Alumni Research Foundation | 2-methylene-(20E)-20(22)-dehydro-19-nor-vitamin D analogs |
US7713953B2 (en) * | 2008-07-10 | 2010-05-11 | Wisconsin Alumni Research Foundation | 2-methylene-(22E)-25-(1-methylene-hexyl)-26,27-cyclo-22-dehydro-19-nor-vitamin D analogs |
US8193170B2 (en) | 2008-07-10 | 2012-06-05 | Wisconsin Alumni Research Foundation | 2-methylene-19,26-dinor-(20R,22E,25R)-vitamin D analogs |
US7893043B2 (en) | 2008-07-10 | 2011-02-22 | Wisconsin Alumni Research Foundation | 2-methylene-(17Z)-17(20)-dehydro-19,21-dinor-vitamin D analogs |
CN102341110B (zh) | 2009-01-27 | 2017-04-12 | 博格有限责任公司 | 用于减轻与化疗有关的副作用的维生素d3及其类似物 |
CN102655869B (zh) | 2009-08-14 | 2016-08-10 | 博格有限责任公司 | 用于治疗脱发的维生素d3及其类似物 |
EP2525799B1 (en) | 2009-10-02 | 2014-09-03 | Wisconsin Alumni Research Foundation | (20s,22e)-2-methylene-19-nor-22-ene-1alpha,25-dihydroxyvitamin d3 analogs |
WO2011041596A2 (en) | 2009-10-02 | 2011-04-07 | Wisconsin Alumni Research Foundation | 19-nor-vitamin d analogs with 1,2-or 3,2-cyclopentene ring |
JP6059716B2 (ja) | 2011-06-03 | 2017-01-11 | ウイスコンシン アラムニ リサーチ ファンデーション | (22E)−2−メチレン−26,27−シクロ−22−デヒドロ−1α−ヒドロキシ−19−ノルビタミンD3誘導体 |
US10479764B2 (en) | 2011-06-28 | 2019-11-19 | Wisconsin Alumni Research Foundation | 2-methylene-(22E)-25-hexanoyl-24-oxo-26,27-cyclo-22-dehydro-19-nor-vitamin D analogs |
WO2013012644A1 (en) | 2011-07-18 | 2013-01-24 | Wisconsin Alumni I Research Foundation | 2-methylene-20(21)-dehydro-19,24,25,26,27,-pentanor-vitamin d analogs |
US9416102B2 (en) | 2013-01-23 | 2016-08-16 | Wisconsin Alumni Research Foundation | (22E)-2-methylene-22-dehydro-1α,24,25-trihydroxy-19-nor-vitamin D3 analogs |
JP6608810B2 (ja) | 2013-05-29 | 2019-11-20 | バーグ エルエルシー | ビタミンdを使用する化学療法誘発性脱毛症の予防又は軽減 |
CN114593917A (zh) * | 2022-03-08 | 2022-06-07 | 安徽理工大学 | 一种基于三元组模型的小样本轴承故障诊断方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0580968B1 (en) * | 1992-05-20 | 1996-08-28 | F. Hoffmann-La Roche Ag | Vitamin D3 fluorinated analogs |
GB9214202D0 (en) | 1992-07-03 | 1992-08-12 | Leo Pharm Prod Ltd | Chemical compounds |
US5565589A (en) | 1993-11-03 | 1996-10-15 | Wisconsin Alumni Research Foundation | 17-formyl-5,6-trans-vitamin D compounds |
DE69508895T2 (de) * | 1994-12-14 | 1999-10-21 | Duphar International Research B.V., Weesp | Vitamin-D-Derivate und Verfahren zur Herstellung dieser Verbindungen |
-
1997
- 1997-10-06 GB GBGB9721156.9A patent/GB9721156D0/en not_active Ceased
-
1998
- 1998-10-02 HU HU0004226A patent/HUP0004226A3/hu unknown
- 1998-10-02 NZ NZ503344A patent/NZ503344A/en unknown
- 1998-10-02 DK DK98947397T patent/DK1023263T3/da active
- 1998-10-02 CZ CZ20001178A patent/CZ295955B6/cs not_active IP Right Cessation
- 1998-10-02 RU RU2000111255/04A patent/RU2196132C2/ru not_active IP Right Cessation
- 1998-10-02 CN CNB988099330A patent/CN1140509C/zh not_active Expired - Fee Related
- 1998-10-02 EP EP98947397A patent/EP1023263B1/en not_active Expired - Lifetime
- 1998-10-02 WO PCT/DK1998/000423 patent/WO1999018070A1/en not_active Application Discontinuation
- 1998-10-02 PL PL339668A patent/PL193060B1/pl unknown
- 1998-10-02 PT PT98947397T patent/PT1023263E/pt unknown
- 1998-10-02 AT AT98947397T patent/ATE219053T1/de not_active IP Right Cessation
- 1998-10-02 KR KR1020007003717A patent/KR20010030966A/ko not_active Application Discontinuation
- 1998-10-02 US US09/543,418 patent/US6399797B1/en not_active Expired - Fee Related
- 1998-10-02 JP JP2000514882A patent/JP2001519327A/ja active Pending
- 1998-10-02 AU AU94323/98A patent/AU740457B2/en not_active Ceased
- 1998-10-02 ES ES98947397T patent/ES2175784T3/es not_active Expired - Lifetime
- 1998-10-02 DE DE69806035T patent/DE69806035T2/de not_active Expired - Fee Related
- 1998-10-02 CA CA002304152A patent/CA2304152A1/en not_active Abandoned
-
2001
- 2001-04-10 HK HK01102530A patent/HK1031868A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
GB9721156D0 (en) | 1997-12-03 |
HUP0004226A3 (en) | 2001-10-29 |
EP1023263A1 (en) | 2000-08-02 |
DE69806035T2 (de) | 2003-01-30 |
NZ503344A (en) | 2002-04-26 |
HK1031868A1 (en) | 2001-06-29 |
ATE219053T1 (de) | 2002-06-15 |
CN1140509C (zh) | 2004-03-03 |
JP2001519327A (ja) | 2001-10-23 |
RU2196132C2 (ru) | 2003-01-10 |
AU9432398A (en) | 1999-04-27 |
CN1274344A (zh) | 2000-11-22 |
PT1023263E (pt) | 2002-10-31 |
CA2304152A1 (en) | 1999-04-15 |
US6399797B1 (en) | 2002-06-04 |
PL193060B1 (pl) | 2007-01-31 |
CZ20001178A3 (cs) | 2000-09-13 |
PL339668A1 (en) | 2001-01-02 |
AU740457B2 (en) | 2001-11-01 |
DE69806035D1 (de) | 2002-07-18 |
EP1023263B1 (en) | 2002-06-12 |
WO1999018070A1 (en) | 1999-04-15 |
HUP0004226A2 (hu) | 2001-04-28 |
CZ295955B6 (cs) | 2005-12-14 |
ES2175784T3 (es) | 2002-11-16 |
KR20010030966A (ko) | 2001-04-16 |
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