DK0927173T3 - Substituerede [2-(1-piperazinyl)ethoxy]methylforbindelser - Google Patents

Substituerede [2-(1-piperazinyl)ethoxy]methylforbindelser

Info

Publication number
DK0927173T3
DK0927173T3 DK97915205T DK97915205T DK0927173T3 DK 0927173 T3 DK0927173 T3 DK 0927173T3 DK 97915205 T DK97915205 T DK 97915205T DK 97915205 T DK97915205 T DK 97915205T DK 0927173 T3 DK0927173 T3 DK 0927173T3
Authority
DK
Denmark
Prior art keywords
piperazinyl
ethoxy
substituted
methyl compounds
methyl
Prior art date
Application number
DK97915205T
Other languages
Danish (da)
English (en)
Inventor
Guy Duchene
Michel Deleers
Guy Bodson
Genevieve Motte
Francoise Lurquin
Original Assignee
Ucb Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Sa filed Critical Ucb Sa
Application granted granted Critical
Publication of DK0927173T3 publication Critical patent/DK0927173T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/205—Radicals derived from carbonic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK97915205T 1996-04-10 1997-03-28 Substituerede [2-(1-piperazinyl)ethoxy]methylforbindelser DK0927173T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BE9600310A BE1010094A3 (fr) 1996-04-10 1996-04-10 Nouveaux [2-(1-piperazinyl)ethoxy] methyle substitues.
PCT/BE1997/000038 WO1997037982A1 (fr) 1996-04-10 1997-03-28 Nouveaux [2-(1-piperazinyl)ethoxy]methyle substitues

Publications (1)

Publication Number Publication Date
DK0927173T3 true DK0927173T3 (da) 2002-09-16

Family

ID=3889663

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97915205T DK0927173T3 (da) 1996-04-10 1997-03-28 Substituerede [2-(1-piperazinyl)ethoxy]methylforbindelser

Country Status (26)

Country Link
US (2) US6140501A (zh)
EP (1) EP0927173B1 (zh)
JP (1) JP2000508634A (zh)
CN (1) CN1072661C (zh)
AR (1) AR006761A1 (zh)
AT (1) ATE219067T1 (zh)
AU (1) AU710835B2 (zh)
BE (1) BE1010094A3 (zh)
BR (1) BR9708763A (zh)
CZ (1) CZ295068B6 (zh)
DE (1) DE69713352T2 (zh)
DK (1) DK0927173T3 (zh)
EA (1) EA000831B1 (zh)
ES (1) ES2177965T3 (zh)
HK (1) HK1018779A1 (zh)
HU (1) HU225478B1 (zh)
IN (1) IN186873B (zh)
MY (1) MY118237A (zh)
NO (1) NO311615B1 (zh)
NZ (1) NZ332057A (zh)
PL (1) PL188819B1 (zh)
PT (1) PT927173E (zh)
RS (1) RS49574B (zh)
TR (1) TR199802025T2 (zh)
WO (1) WO1997037982A1 (zh)
ZA (1) ZA972973B (zh)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0919550A1 (en) 1997-11-26 1999-06-02 Ucb, S.A. Pseudopolymorphic forms of 2-2-4-bis(4-fluorophenyl)methyl-1-piperazinyl-ethoxy acetic acid dihydrochloride
IL124195A (en) * 1998-04-23 2000-08-31 Chemagis Ltd Process for the preparation of esters of 2-¬4-¬4-chlorophenyl¾phenylmethyl¾-1-piperazinyl¬ethoxy¾acetic acid
CZ304892B6 (cs) * 1999-11-30 2015-01-07 EGIS Gyógyszergyár Rt. Způsob přípravy {2-[4-(α-fenyl-p-chlorbenzyl)piperazin-1-yl]ethoxy}octové kyseliny a nové meziprodukty
US7199241B1 (en) 2001-05-29 2007-04-03 Ucb, S.A. Process for preparing (S) and (R)-2-[4-(4-chlorobenzhydryl)piperazin-1-yl]-ethoxyacetamide
US6977301B1 (en) 2001-05-29 2005-12-20 Ucb, S.A. Process for preparing (S) and (R)—2-[4-(4-chlorobenzhydryl)piperazin-1-yl]-ethoxyacetamide
US6838052B2 (en) 2001-06-29 2005-01-04 Symyx Technologies, Inc. In-situ injection and materials screening device
CA2454564A1 (en) * 2001-07-26 2003-02-06 Ucb, S.A. Process for the preparation of 2-(2-(4-(bis(4-fluorophenyl)methyl)-piperazin-1-yl)ethoxy)acetic acid derivatives or corresponding salt forms thereof and intermediates therefor
US7160513B2 (en) 2002-12-20 2007-01-09 Symyx Technologies, Inc. Batch reactor with injection system
US20040266787A1 (en) * 2003-03-25 2004-12-30 Dr. Reddy's Laboratories Limited Novel amorphous form of [2-[4-[(4-chlorophenyl)-phenyl methyl]-1-piperazinyl]ethoxy]acetic acid and process for the preparation thereof
US20050020608A1 (en) * 2003-03-25 2005-01-27 Dr. Reddy's Laboratories Limited Crystalline cetirizine monohydrochloride
WO2004103982A1 (en) * 2003-05-21 2004-12-02 Wockhardt Limited 2-[2-[4-[(4-chlorophenyl) phenylmethyl]-1-piperazinyl]ethoxy]acetic acid monohydrochloride as anti-allergenic compound and process for its production
KR100503443B1 (ko) * 2004-02-02 2005-07-22 한림제약(주) 광학적으로 활성인 세티리진 또는 그의 염의 제조방법
WO2006050909A1 (en) * 2004-11-10 2006-05-18 Ucb Farchim Sa Novel forms of efletirizine dihydrochloride, processes for making them and pharmaceutical compositions including them
EP1845088B1 (en) * 2006-04-10 2009-07-22 Ranbaxy Laboratories Limited An improved process for the preparation of aripipirazole
US20110172425A1 (en) * 2008-09-17 2011-07-14 Calyx Chemicals And Pharmaceuticals Pvt. Ltd. Novel water based process for the preparation of substituted diphenylmethyl piperazines
KR101418404B1 (ko) 2012-01-06 2014-07-10 한미약품 주식회사 레보세티리진 또는 이의 약학적으로 허용가능한 염 및 몬테루카스트 또는 이의 약학적으로 허용가능한 염을 함유하는 안정한 경구투여용 약학 제제
KR102226833B1 (ko) 2013-06-28 2021-03-12 한미약품 주식회사 레보세티리진 및 몬테루카스트를 포함하는 안정성이 개선된 복합 과립 제형

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH505116A (it) * 1966-11-21 1971-03-31 Crc Ricerca Chim Metodo per l'ottenimento di derivati della piperazina
GB1184395A (en) * 1967-03-08 1970-03-18 Egyt Gyogyszervegyeszeti Gyar Substituted Piperazine Derivatives
DK154078C (da) * 1981-02-06 1989-05-22 Ucb Sa Analogifremgangsmaade til fremstilling af 2-(2-(4-(diphenyl-methyl)-1-piperazinyl)ethoxy)-acetamider eller syreadditionssalte heraf
GB8827391D0 (en) * 1988-11-23 1988-12-29 Ucb Sa Process for preparation of 2-(2-(4-((4-chlorophenyl)phenylmethyl)-1-pipera-zinyl)ethoxy)-acetic acid & its dihydrochloride
GB8827390D0 (en) * 1988-11-23 1988-12-29 Ucb Sa Process for preparation of 2-(2-(4-((4-chlorophenyl)phenylmethyl)-1-pipera-zinyl)ethoxy)-acetic acid & its dihydrochloride

Also Published As

Publication number Publication date
NO984738D0 (no) 1998-10-09
NZ332057A (en) 2000-03-27
DE69713352T2 (de) 2003-02-20
CN1215395A (zh) 1999-04-28
PL329307A1 (en) 1999-03-15
MY118237A (en) 2004-09-30
RS49574B (sr) 2007-04-10
IN186873B (zh) 2001-12-01
ZA972973B (en) 1997-11-03
US6140501A (en) 2000-10-31
AU2281897A (en) 1997-10-29
AU710835B2 (en) 1999-09-30
EP0927173A1 (fr) 1999-07-07
NO311615B1 (no) 2001-12-17
EA000831B1 (ru) 2000-04-24
CN1072661C (zh) 2001-10-10
BR9708763A (pt) 1999-08-03
DE69713352D1 (en) 2002-07-18
PT927173E (pt) 2002-11-29
WO1997037982A1 (fr) 1997-10-16
HU225478B1 (en) 2006-12-28
HK1018779A1 (en) 2000-01-07
HUP9901804A3 (en) 2000-06-28
CZ295068B6 (cs) 2005-05-18
HUP9901804A2 (hu) 1999-09-28
EP0927173B1 (fr) 2002-06-12
AR006761A1 (es) 1999-09-29
BE1010094A3 (fr) 1997-12-02
PL188819B1 (pl) 2005-04-29
TR199802025T2 (xx) 1999-01-18
ATE219067T1 (de) 2002-06-15
ES2177965T3 (es) 2002-12-16
JP2000508634A (ja) 2000-07-11
EA199800879A1 (ru) 1999-02-25
NO984738L (no) 1998-12-08
US6255487B1 (en) 2001-07-03
YU44198A (sh) 1999-07-28
CZ315198A3 (cs) 1999-03-17

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