DK0709085T3 - Depotpræparat - Google Patents
DepotpræparatInfo
- Publication number
- DK0709085T3 DK0709085T3 DK95115568T DK95115568T DK0709085T3 DK 0709085 T3 DK0709085 T3 DK 0709085T3 DK 95115568 T DK95115568 T DK 95115568T DK 95115568 T DK95115568 T DK 95115568T DK 0709085 T3 DK0709085 T3 DK 0709085T3
- Authority
- DK
- Denmark
- Prior art keywords
- microcapsule
- polymer
- active substance
- physiologically active
- water
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/773—Nanoparticle, i.e. structure having three dimensions of 100 nm or less
- Y10S977/775—Nanosized powder or flake, e.g. nanosized catalyst
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/788—Of specified organic or carbon-based composition
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/788—Of specified organic or carbon-based composition
- Y10S977/797—Lipid particle
- Y10S977/798—Lipid particle having internalized material
- Y10S977/799—Containing biological material
- Y10S977/801—Drug
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/906—Drug delivery
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/915—Therapeutic or pharmaceutical composition
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP23684694 | 1994-09-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0709085T3 true DK0709085T3 (da) | 2001-02-19 |
Family
ID=17006666
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK00106329T DK1022020T3 (da) | 1994-09-30 | 1995-10-02 | Præparat med forsinket frigivelse |
DK95115568T DK0709085T3 (da) | 1994-09-30 | 1995-10-02 | Depotpræparat |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK00106329T DK1022020T3 (da) | 1994-09-30 | 1995-10-02 | Præparat med forsinket frigivelse |
Country Status (6)
Country | Link |
---|---|
US (1) | US6117455A (da) |
EP (2) | EP0709085B1 (da) |
AT (2) | ATE198981T1 (da) |
CA (1) | CA2159552A1 (da) |
DE (2) | DE69520021T2 (da) |
DK (2) | DK1022020T3 (da) |
Families Citing this family (123)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100354270B1 (ko) | 1993-11-19 | 2003-02-11 | 알커메스 컨트롤드 테라포이틱스 인코퍼레이티드 Ii | 마이크로캡슐화된3-피페리디닐-치환된1,2-벤즈이속사졸및1,2-벤즈이소티아졸 |
US6051256A (en) | 1994-03-07 | 2000-04-18 | Inhale Therapeutic Systems | Dispersible macromolecule compositions and methods for their preparation and use |
US20110196039A9 (en) * | 1994-10-05 | 2011-08-11 | Kaesemeyer Wayne H | Controlled release arginine formulations |
DE69620165T2 (de) * | 1995-04-26 | 2002-10-31 | Takeda Chemical Industries, Ltd. | Piperazinone als inhibitoren von blutplattchenaggregation |
US6143211A (en) * | 1995-07-21 | 2000-11-07 | Brown University Foundation | Process for preparing microparticles through phase inversion phenomena |
EP0765660A3 (en) * | 1995-09-28 | 1998-09-23 | Takeda Chemical Industries, Ltd. | Microcapsules comprising 2-piperazinone-1-acetic acid compounds |
TW403653B (en) * | 1995-12-25 | 2000-09-01 | Otsuka Pharma Co Ltd | Dry compositions |
EP0793965A3 (en) * | 1996-02-29 | 1999-02-24 | Tano, Yasuo | Prophylactic/therapeutic composition for secondary cataract |
DE69717263T2 (de) * | 1996-03-28 | 2003-07-24 | Takeda Chemical Industries, Ltd. | Zubereitung mit verzögerter freisetzung und deren herstellung |
US20030203036A1 (en) | 2000-03-17 | 2003-10-30 | Gordon Marc S. | Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients |
US6126919A (en) * | 1997-02-07 | 2000-10-03 | 3M Innovative Properties Company | Biocompatible compounds for pharmaceutical drug delivery systems |
GB9703673D0 (en) * | 1997-02-21 | 1997-04-09 | Bradford Particle Design Ltd | Method and apparatus for the formation of particles |
FR2776516B1 (fr) * | 1998-03-25 | 2001-05-25 | Pharma Biotech | Compositions presentant une liberation prolongee et leur procede de preparation |
FR2762318B1 (fr) * | 1997-04-18 | 1999-09-17 | Pharma Biotech | Compositions presentant une liberation prolongee et leur procede de preparation |
AR012448A1 (es) * | 1997-04-18 | 2000-10-18 | Ipsen Pharma Biotech | Composicion en forma de microcapsulas o de implantes que comprende un excipiente biodegradable, polimero o co-polimero, o una mezcla de talesexcipientes, y una sustancia activa o una mezcla de sustancias activas, procedimiento para la preparacion de una sustancia soluble en agua de elevada |
US6287587B2 (en) * | 1997-07-15 | 2001-09-11 | Takeda Chemical Industries, Ltd. | Process for producing sustained-release preparation by in-water drying |
US20060165606A1 (en) * | 1997-09-29 | 2006-07-27 | Nektar Therapeutics | Pulmonary delivery particles comprising water insoluble or crystalline active agents |
US6565885B1 (en) * | 1997-09-29 | 2003-05-20 | Inhale Therapeutic Systems, Inc. | Methods of spray drying pharmaceutical compositions |
CN1180768C (zh) * | 1998-01-21 | 2004-12-22 | 武田药品工业株式会社 | 缓释制剂的制备方法 |
US8236352B2 (en) * | 1998-10-01 | 2012-08-07 | Alkermes Pharma Ireland Limited | Glipizide compositions |
US20080213378A1 (en) * | 1998-10-01 | 2008-09-04 | Elan Pharma International, Ltd. | Nanoparticulate statin formulations and novel statin combinations |
US20040013613A1 (en) * | 2001-05-18 | 2004-01-22 | Jain Rajeev A | Rapidly disintegrating solid oral dosage form |
HU230454B1 (hu) * | 1998-11-02 | 2016-07-28 | Alkermes Pharma Ireland Limited | Metilfenidátot tartalmazó módosított felszabadulású sokszemcsés készítmény |
US6969529B2 (en) * | 2000-09-21 | 2005-11-29 | Elan Pharma International Ltd. | Nanoparticulate compositions comprising copolymers of vinyl pyrrolidone and vinyl acetate as surface stabilizers |
US6204308B1 (en) | 1999-03-01 | 2001-03-20 | Novartis Ag | Organic compounds |
EG23951A (en) * | 1999-03-25 | 2008-01-29 | Otsuka Pharma Co Ltd | Cilostazol preparation |
DE19949897A1 (de) * | 1999-10-15 | 2001-04-19 | Rainer Rogasch | Formkörper und Verfahren zu dessen Herstellung |
US8404217B2 (en) | 2000-05-10 | 2013-03-26 | Novartis Ag | Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use |
US7871598B1 (en) | 2000-05-10 | 2011-01-18 | Novartis Ag | Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use |
DK1280520T4 (da) | 2000-05-10 | 2018-06-25 | Novartis Ag | Phospholipid-baserede pulvere til medikamentafgivelse |
US20040156872A1 (en) * | 2000-05-18 | 2004-08-12 | Elan Pharma International Ltd. | Novel nimesulide compositions |
US7575761B2 (en) * | 2000-06-30 | 2009-08-18 | Novartis Pharma Ag | Spray drying process control of drying kinetics |
US7198795B2 (en) * | 2000-09-21 | 2007-04-03 | Elan Pharma International Ltd. | In vitro methods for evaluating the in vivo effectiveness of dosage forms of microparticulate of nanoparticulate active agent compositions |
US7998507B2 (en) * | 2000-09-21 | 2011-08-16 | Elan Pharma International Ltd. | Nanoparticulate compositions of mitogen-activated protein (MAP) kinase inhibitors |
GB0027357D0 (en) * | 2000-11-09 | 2000-12-27 | Bradford Particle Design Plc | Particle formation methods and their products |
WO2002041829A2 (en) * | 2000-11-20 | 2002-05-30 | Pr Pharmaceuticals, Inc. | Oral nanosphere delivery |
CA2680475A1 (en) | 2000-12-28 | 2002-07-11 | Shigeyuki Takada | Sustained-release preparation |
US6558702B2 (en) * | 2001-04-13 | 2003-05-06 | Alkermes Controlled Therapeutics, Inc. | Method of modifying the release profile of sustained release compositions |
US20040126900A1 (en) * | 2001-04-13 | 2004-07-01 | Barry Stephen E | High affinity peptide- containing nanoparticles |
EG24184A (en) | 2001-06-15 | 2008-10-08 | Otsuka Pharma Co Ltd | Dry powder inhalation system for transpulmonary |
WO2003000156A1 (en) | 2001-06-22 | 2003-01-03 | Southern Biosystems, Inc. | Zero-order prolonged release coaxial implants |
GB0208742D0 (en) | 2002-04-17 | 2002-05-29 | Bradford Particle Design Ltd | Particulate materials |
WO2003013683A1 (en) * | 2001-08-08 | 2003-02-20 | Brown University Research Foundation | Methods for micronization of hydrophobic drugs |
EP1446104B2 (en) * | 2001-11-01 | 2011-08-03 | Novartis AG | Spray drying methods |
WO2003053411A1 (en) | 2001-12-19 | 2003-07-03 | Nektar Therapeutics | Pulmonary delivery of aminoglycosides |
JP4598399B2 (ja) | 2002-02-04 | 2010-12-15 | エラン ファーマ インターナショナル,リミティド | 表面安定剤としてリゾチームを有するナノ粒子組成物 |
CA2474698C (en) * | 2002-02-08 | 2009-07-21 | Alkermes Controlled Therapeutics, Inc. | Polymer-based compositions for sustained release |
GB0216562D0 (en) | 2002-04-25 | 2002-08-28 | Bradford Particle Design Ltd | Particulate materials |
US9339459B2 (en) | 2003-04-24 | 2016-05-17 | Nektar Therapeutics | Particulate materials |
AU2003261167A1 (en) * | 2002-07-16 | 2004-02-02 | Elan Pharma International, Ltd | Liquid dosage compositions of stable nanoparticulate active agents |
DE10234165B4 (de) * | 2002-07-26 | 2008-01-03 | Advanced Micro Devices, Inc., Sunnyvale | Verfahren zum Füllen eines Grabens, der in einem Substrat gebildet ist, mit einem isolierenden Material |
US7214387B2 (en) | 2002-08-02 | 2007-05-08 | Penwest Pharmaceuticals Company | Sustained release formulations of metformin |
US8986737B2 (en) | 2002-09-05 | 2015-03-24 | Wm. Marsh Rice University | Antibiotic microspheres for treatment and prevention of osteomyelitis and enhancement of bone regrowth |
WO2004022000A2 (en) * | 2002-09-05 | 2004-03-18 | Ambrose Catherine G | Antibiotic microspheres for treatment of infections and osteomyelitis |
JP4690040B2 (ja) * | 2002-09-11 | 2011-06-01 | 田辺三菱製薬株式会社 | マイクロスフェアの製法及び製造装置 |
JP2006503865A (ja) * | 2002-09-30 | 2006-02-02 | アキュスフィア, インコーポレイテッド | 吸入のための徐放性の多孔性微粒子 |
US20040121003A1 (en) * | 2002-12-19 | 2004-06-24 | Acusphere, Inc. | Methods for making pharmaceutical formulations comprising deagglomerated microparticles |
US6962006B2 (en) | 2002-12-19 | 2005-11-08 | Acusphere, Inc. | Methods and apparatus for making particles using spray dryer and in-line jet mill |
US6936273B2 (en) * | 2002-12-20 | 2005-08-30 | Idexx Laboratories, Inc. | Liposomal analgesic formulation and use |
EP1572152B1 (en) * | 2002-12-20 | 2008-02-13 | Idexx Laboratories, Inc. | Liposomal analgesic formulation comprising diclofenac and its use for treatment of horses |
JP4808970B2 (ja) | 2002-12-30 | 2011-11-02 | ネクター セラピューティクス | 噴霧乾燥システム |
JP2004331750A (ja) * | 2003-05-02 | 2004-11-25 | Canon Inc | ポリヒドロキシアルカノエートを含有する磁性構造体及びその製造方法ならびにその用途 |
US20050084455A1 (en) * | 2003-10-16 | 2005-04-21 | Council Of Scientific & Industrial Research | Inhalable biodegradable microparticles for target-specific drug delivery in tuberculosis and a process thereof |
US20070207138A1 (en) * | 2004-03-31 | 2007-09-06 | Aspion Co., Ltd. | S/O Type Pharmaceutical Preparation and Method for Producing the Same |
DK1742616T3 (da) * | 2004-04-30 | 2015-01-12 | Abraxis Bioscience Llc | Mikrosfære-afgivelses-system til forlænget afgivelse og fremgangsmåder til fremstilling og anvendelse af samme |
WO2005107714A2 (en) * | 2004-05-05 | 2005-11-17 | Alkermes Controlled Therapeutics, Inc. | Method of forming microparticles that include a bisphosphonate and a polymer |
US20060121112A1 (en) * | 2004-12-08 | 2006-06-08 | Elan Corporation, Plc | Topiramate pharmaceutical composition |
EP1679065A1 (en) | 2005-01-07 | 2006-07-12 | OctoPlus Sciences B.V. | Controlled release compositions for interferon based on PEGT/PBT block copolymers |
AU2006235483B2 (en) * | 2005-04-12 | 2010-11-25 | Elan Pharma International Limited | Controlled release compositions comprising a cephalosporin for the treatment of a bacterial infection |
CA2611506A1 (en) * | 2005-05-23 | 2006-11-23 | Elan Pharma International Limited | Nanoparticulate and controlled release compositions comprising a platelet aggregation inhibitor |
WO2007037790A2 (en) * | 2005-06-08 | 2007-04-05 | Elan Corporation, Plc | Modified release famciclovir compositions |
US7861728B2 (en) * | 2006-02-10 | 2011-01-04 | R.J. Reynolds Tobacco Company | Smokeless tobacco composition having an outer and inner pouch |
CA2631492A1 (en) * | 2005-12-15 | 2007-06-21 | Acusphere, Inc. | Processes for making particle-based pharmaceutical formulations for oral administration |
CA2631493A1 (en) * | 2005-12-15 | 2007-06-21 | Acusphere, Inc. | Processes for making particle-based pharmaceutical formulations for pulmonary or nasal administration |
US20070142287A1 (en) * | 2005-12-20 | 2007-06-21 | Biomed Solutions, Llc | Compositions And Methods For Treatment Of Cancer |
US7810507B2 (en) | 2006-02-10 | 2010-10-12 | R. J. Reynolds Tobacco Company | Smokeless tobacco composition |
US7789089B2 (en) | 2006-08-04 | 2010-09-07 | R. J. Reynolds Tobacco Company | Filtered cigarette possessing tipping material |
KR100816065B1 (ko) * | 2006-11-27 | 2008-03-24 | 동국제약 주식회사 | 초기 방출억제 특성이 우수한 서방출성 마이크로캡슐의제조방법 및 이에 의해 제조되는 마이크로캡슐 |
HUE026884T2 (en) | 2007-02-11 | 2016-08-29 | Map Pharmaceuticals Inc | DHE is a therapeutic method of administration for the rapid relief of migraine while minimizing side effects |
JP2010521494A (ja) * | 2007-03-16 | 2010-06-24 | エラン・ファルマ・インターナショナル・リミテッド | 麻薬性および非麻薬性鎮痛剤の組み合わせ |
US20150164835A1 (en) * | 2007-05-22 | 2015-06-18 | Pisgah Laboratories, Inc. | Opioid Salts with Release Properties and Characteristics Useful for Abuse Deterrent Drug Product Formulations |
JP5339635B2 (ja) | 2007-07-23 | 2013-11-13 | アール・ジエイ・レイノルズ・タバコ・カンパニー | 無煙タバコ組成物およびそれを使用するためのタバコ処理方法 |
EP2315571A4 (en) * | 2008-07-16 | 2013-05-01 | Surmodics Pharmaceuticals Inc | METHOD FOR PRODUCING MICROPARTICLES WITH BIOACTIVE PEPTIDES |
US8464726B2 (en) | 2009-08-24 | 2013-06-18 | R.J. Reynolds Tobacco Company | Segmented smoking article with insulation mat |
US8760508B2 (en) * | 2010-01-13 | 2014-06-24 | R.J. Reynolds Tobacco Company | Filtered smoking article inspection system, and associated method |
ES2681875T3 (es) * | 2010-01-22 | 2018-09-17 | Concept Medical Research Private Limited | Dispositivos médicos insertables con una capa porosa para administrar nanovehículos a un sitio objetivo y métodos de preparación del mismo |
US9138309B2 (en) | 2010-02-05 | 2015-09-22 | Allergan, Inc. | Porous materials, methods of making and uses |
US9205577B2 (en) * | 2010-02-05 | 2015-12-08 | Allergan, Inc. | Porogen compositions, methods of making and uses |
US20110271968A1 (en) | 2010-05-07 | 2011-11-10 | Carolyn Rierson Carpenter | Filtered Cigarette With Modifiable Sensory Characteristics |
US11202853B2 (en) * | 2010-05-11 | 2021-12-21 | Allergan, Inc. | Porogen compositions, methods of making and uses |
US10028520B2 (en) | 2010-09-02 | 2018-07-24 | R.J. Reynolds Tobacco Company | Apparatus for manufacturing a smokeless tobacco product incorporating an object, and associated method |
US8893725B2 (en) | 2011-01-28 | 2014-11-25 | R. J. Reynolds Tobacco Company | Polymeric materials derived from tobacco |
CA2767773C (en) | 2011-02-11 | 2015-11-24 | Grain Processing Corporation | Composition comprising a salt and a crystallization interrupter |
EP2525367A1 (en) | 2011-05-20 | 2012-11-21 | Areva NP | Nuclear fuel assembly spacer grid and corresponding nuclear fuel assembly |
US20130085052A1 (en) | 2011-09-29 | 2013-04-04 | R. J. Reynolds Tobacco Company | Apparatus for Inserting Microcapsule Objects into a Filter Element of a Smoking Article, and Associated Method |
US8831764B2 (en) | 2011-10-17 | 2014-09-09 | R. J. Reynolds Tobacco Company | Cigarette package coding system and associated method |
ES2692949T3 (es) | 2012-03-08 | 2018-12-05 | Consejo Superior De Investigaciones Científicas (Csic) | Recubrimiento con propiedades fotocrómicas, método de obtención de dicho recubrimiento y uso aplicable a artículos ópticos y superficies acristaladas |
US9664570B2 (en) | 2012-11-13 | 2017-05-30 | R.J. Reynolds Tobacco Company | System for analyzing a smoking article filter associated with a smoking article, and associated method |
AP2015008369A0 (en) * | 2013-04-15 | 2015-04-30 | Sunsho Pharmaceutical Co Ltd | Disintegrable capsule, manufacturing method for same, and smoking device containing said disintegrable capsule |
TWI482634B (zh) | 2013-10-24 | 2015-05-01 | Ind Tech Res Inst | 生醫組合物 |
US9844232B2 (en) | 2014-03-11 | 2017-12-19 | R.J. Reynolds Tobacco Company | Smoking article inspection system and associated method |
US10063814B2 (en) | 2014-03-12 | 2018-08-28 | R.J. Reynolds Tobacco Company | Smoking article package inspection system and associated method |
US9956164B2 (en) | 2014-04-16 | 2018-05-01 | Veyx-Pharma Gmbh | Veterinary pharmaceutical composition and use thereof |
DE102014012020A1 (de) * | 2014-08-13 | 2016-02-18 | Clariant International Ltd. | VOC-arme Amine als oberflächenaktiver Bestandteil in Dispersionen |
US20160157515A1 (en) | 2014-12-05 | 2016-06-09 | R.J. Reynolds Tobacco Company | Smokeless tobacco pouch |
MX2017012877A (es) | 2015-04-07 | 2018-07-06 | Church & Dwight Co Inc | Composiciones gomosas de multicomponentes con nucleo suave. |
US11641874B2 (en) | 2015-09-09 | 2023-05-09 | R.J. Reynolds Tobacco Company | Flavor delivery article |
US10532046B2 (en) | 2015-12-03 | 2020-01-14 | Niconovum Usa, Inc. | Multi-phase delivery compositions and products incorporating such compositions |
US20170172200A1 (en) | 2015-12-16 | 2017-06-22 | R.J. Reynolds Tobacco Company | Flavor additive accessory |
ES2925536T3 (es) | 2018-02-09 | 2022-10-18 | Topsoe As | Procedimiento para producir alfa-hidroxicompuestos y usos de los mismos |
US11206864B2 (en) | 2018-03-26 | 2021-12-28 | Rai Strategic Holdings, Inc. | Aerosol delivery device providing flavor control |
US11617744B2 (en) | 2019-12-09 | 2023-04-04 | Nico Ventures Trading Limited | Moist oral compositions |
US11793230B2 (en) | 2019-12-09 | 2023-10-24 | Nicoventures Trading Limited | Oral products with improved binding of active ingredients |
US11969502B2 (en) | 2019-12-09 | 2024-04-30 | Nicoventures Trading Limited | Oral products |
US11872231B2 (en) | 2019-12-09 | 2024-01-16 | Nicoventures Trading Limited | Moist oral product comprising an active ingredient |
US11826462B2 (en) | 2019-12-09 | 2023-11-28 | Nicoventures Trading Limited | Oral product with sustained flavor release |
US11259569B2 (en) | 2019-12-10 | 2022-03-01 | Rai Strategic Holdings, Inc. | Aerosol delivery device with downstream flavor cartridge |
CN111149922B (zh) * | 2020-01-15 | 2023-05-16 | 烟台市三维饲料有限公司 | 一种具有免疫、生长促进功能的脾脏源饲料添加剂及其制备方法与应用 |
KR20230068413A (ko) | 2020-09-11 | 2023-05-17 | 니코벤처스 트레이딩 리미티드 | 알지네이트-기반 기재 |
KR20240044428A (ko) | 2021-07-09 | 2024-04-04 | 니코벤처스 트레이딩 리미티드 | 압출 구조물 |
WO2024079722A1 (en) | 2022-10-14 | 2024-04-18 | Nicoventures Trading Limited | Capsule-containing pouched products |
WO2024089588A1 (en) | 2022-10-24 | 2024-05-02 | Nicoventures Trading Limited | Shaped pouched products |
WO2024095163A1 (en) | 2022-11-01 | 2024-05-10 | Nicoventures Trading Limited | Oral composition comprising encapsulated ph adjusting agent |
Family Cites Families (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NO139560C (no) * | 1972-04-29 | 1979-04-04 | Takeda Chemical Industries Ltd | Analogifremgangsmaate til fremstilling av terapeutisk virksomme nonapeptidamid-derivater |
US3845668A (en) * | 1973-02-20 | 1974-11-05 | Mallory & Co Inc P R | Clutch and gear train utilizing same |
JPS528375B2 (da) * | 1973-07-02 | 1977-03-09 | ||
FR2238700B1 (da) | 1973-07-24 | 1977-10-14 | Takeda Chemical Industries Ltd | |
JPS5726506B2 (da) * | 1974-03-08 | 1982-06-04 | ||
AT347054B (de) * | 1973-09-29 | 1978-12-11 | Takeda Chemical Industries Ltd | Verfahren zur herstellung von neuen nonapeptidamid-derivaten |
DE2649146A1 (de) * | 1975-10-29 | 1977-05-12 | Parke Davis & Co | Nonapeptide |
US4087390A (en) * | 1977-02-02 | 1978-05-02 | Eli Lilly And Company | Somatostatin analogs and intermediates thereto |
US4093574A (en) * | 1977-02-02 | 1978-06-06 | Eli Lilly And Company | Somatostatin analogs and intermediates thereto |
JPS5944308B2 (ja) * | 1976-03-23 | 1984-10-29 | 武田薬品工業株式会社 | ペプタイド |
US4100117A (en) * | 1977-04-21 | 1978-07-11 | Eli Lilly And Company | Somatostatin analogs and intermediates thereto |
US4124577A (en) * | 1977-06-13 | 1978-11-07 | Warner-Lambert | Nonapeptides and methods for their production |
US4253998A (en) * | 1979-03-09 | 1981-03-03 | American Home Products Corporation | Peptides related to somatostatin |
JPS54148722A (en) * | 1978-05-12 | 1979-11-21 | Takeda Chem Ind Ltd | Nonapeptide and its preparation |
US4277394A (en) * | 1979-04-23 | 1981-07-07 | Takeda Chemical Industries, Ltd | Tetrapeptidehydrazide derivatives |
US4317815A (en) * | 1979-06-13 | 1982-03-02 | Coy David Howard | LH-RH Antagonists |
US4253997A (en) * | 1979-12-17 | 1981-03-03 | American Home Products Corporation | Anti-ovulatory decapeptides |
JPS5692846A (en) * | 1979-12-27 | 1981-07-27 | Takeda Chem Ind Ltd | Tetrapeptide derivative and its preparation |
PH19942A (en) * | 1980-11-18 | 1986-08-14 | Sintex Inc | Microencapsulation of water soluble polypeptides |
SE8103843L (sv) * | 1981-06-18 | 1982-12-19 | Astra Laekemedel Ab | Farmaceutisk mixtur |
JPH0678425B2 (ja) * | 1984-07-06 | 1994-10-05 | 和光純薬工業株式会社 | 重合体の新規製造法 |
DE3678308D1 (de) * | 1985-02-07 | 1991-05-02 | Takeda Chemical Industries Ltd | Verfahren zur herstellung von mikrokapseln. |
US4962091A (en) * | 1986-05-23 | 1990-10-09 | Syntex (U.S.A.) Inc. | Controlled release of macromolecular polypeptides |
DE3738228A1 (de) * | 1987-11-11 | 1989-05-24 | Hoechst Ag | Verfahren zur herstellung von bioabbaubaren mikrokapseln wasserloeslicher peptide und proteine sowie nach diesem verfahren erhaltene mikrokapseln |
ES2059571T3 (es) * | 1988-01-19 | 1994-11-16 | Takeda Chemical Industries Ltd | Fumagilina como agente angiostatico. |
JP2827287B2 (ja) * | 1988-07-05 | 1998-11-25 | 武田薬品工業株式会社 | 水溶性薬物含有徐放型マイクロカプセル |
ES2099064T3 (es) * | 1988-09-01 | 1997-05-16 | Takeda Chemical Industries Ltd | Derivados de fumagillol. |
KR0141692B1 (ko) * | 1988-09-01 | 1998-06-01 | 우메모또 요시마사 | 맥관 형성 억제제 |
DE69004598T2 (de) * | 1989-03-06 | 1994-03-24 | Takeda Chemical Industries Ltd | 6-Amino-6-desoxyfumagillole, ihre Herstellung und ihre Verwendung. |
FR2649617A1 (fr) * | 1989-07-12 | 1991-01-18 | Veprol | Dispositif de delivrance d'un principe actif pharmacologique par pompage electrolytique |
EP0415294A3 (en) * | 1989-08-31 | 1991-06-12 | Takeda Chemical Industries, Ltd. | Cyclohexanol derivatives, production and use thereof |
WO1991013595A1 (en) * | 1990-03-15 | 1991-09-19 | The United States Of America, As Represented By The Secretary Of The Army | Chemotherapeutic treatment of bacterial infections with an antibiotic encapsulated within a biodegradable polymeric matrix |
AU667662B2 (en) | 1990-07-13 | 1996-04-04 | Regents Of The University Of California, The | Parathyroid hormone analogues modified at positions 3, 6 or 9 |
GB9020544D0 (en) * | 1990-09-20 | 1990-10-31 | Sandoz Ltd | Improvements in or relating to organic compounds |
JPH0532696A (ja) * | 1990-09-28 | 1993-02-09 | Takeda Chem Ind Ltd | 副甲状腺ホルモン誘導体 |
ZA918168B (en) * | 1990-10-16 | 1993-04-14 | Takeda Chemical Industries Ltd | Prolonged release preparation and polymers thereof. |
JP3303211B2 (ja) * | 1991-04-26 | 2002-07-15 | 武田薬品工業株式会社 | bFGFムテインおよびその製造法 |
EP0535937B2 (en) * | 1991-10-01 | 2008-05-21 | Takeda Chemical Industries, Ltd. | Prolonged release microparticle preparation and production of the same |
DE69316101T2 (de) * | 1992-08-07 | 1998-10-22 | Takeda Chemical Industries Ltd | Herstellung von Mikrokapseln, die wasserlösliche Arzneimittel enthalten |
JP3841309B2 (ja) * | 1993-10-22 | 2006-11-01 | ジェネンテック・インコーポレーテッド | 流動床乾燥工程を含んでなるミクロスフェアの製造方法 |
DE69620165T2 (de) * | 1995-04-26 | 2002-10-31 | Takeda Chemical Industries, Ltd. | Piperazinone als inhibitoren von blutplattchenaggregation |
-
1995
- 1995-09-28 US US08/535,386 patent/US6117455A/en not_active Expired - Fee Related
- 1995-09-29 CA CA002159552A patent/CA2159552A1/en not_active Abandoned
- 1995-10-02 DE DE69520021T patent/DE69520021T2/de not_active Expired - Lifetime
- 1995-10-02 EP EP95115568A patent/EP0709085B1/en not_active Expired - Lifetime
- 1995-10-02 DK DK00106329T patent/DK1022020T3/da active
- 1995-10-02 DK DK95115568T patent/DK0709085T3/da active
- 1995-10-02 AT AT95115568T patent/ATE198981T1/de active
- 1995-10-02 EP EP00106329A patent/EP1022020B1/en not_active Expired - Lifetime
- 1995-10-02 AT AT00106329T patent/ATE231390T1/de not_active IP Right Cessation
- 1995-10-02 DE DE69529486T patent/DE69529486T2/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1022020B1 (en) | 2003-01-22 |
DE69529486D1 (de) | 2003-02-27 |
EP1022020A2 (en) | 2000-07-26 |
EP0709085A1 (en) | 1996-05-01 |
CA2159552A1 (en) | 1996-03-31 |
DE69520021T2 (de) | 2001-09-13 |
DE69520021D1 (de) | 2001-03-08 |
DE69529486T2 (de) | 2003-12-04 |
US6117455A (en) | 2000-09-12 |
DK1022020T3 (da) | 2003-03-03 |
EP0709085B1 (en) | 2001-01-31 |
EP1022020A3 (en) | 2001-04-25 |
ATE231390T1 (de) | 2003-02-15 |
ATE198981T1 (de) | 2001-02-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK0709085T3 (da) | Depotpræparat | |
EP0765660A3 (en) | Microcapsules comprising 2-piperazinone-1-acetic acid compounds | |
DE69316101D1 (de) | Herstellung von Mikrokapseln, die wasserlösliche Arzneimittel enthalten | |
RU95102329A (ru) | Способ и стабилизированная каталитическая система для получения олефинов | |
CA2074320A1 (en) | Process for the preparation of microspheres made of a biodegradable polymeric material | |
KR970703133A (ko) | 중합체 매트릭스 중의 활성제의 고용체 형태로서의 활성제 제제의 제조 방법 및 그에 의해 얻어진 활성제 제제(Process for Producing Active Agent Preparations in the Form of a Solid Solution of the Active Agent in a Polymer Matrix and Active Agent Preparations Obtained Thereby) | |
EP1905828A3 (en) | Optical sorting method | |
ATE304343T1 (de) | Mikrokapseln - iv | |
CA2119573A1 (en) | Process and kit for dyeing hair | |
ATE258777T1 (de) | Mikrokapseln - ii | |
CA2306824A1 (en) | Encapsulation method | |
BR9701263A (pt) | Processo para preparar suspensões de carotenóides ou retinóides finamente dispersas suspensão de carotenóide ou retinóide e uso da suspensão de carotenóide ou retinóide ou do pó de carotenóide ou retinóide finamente disperso | |
ES2175908T3 (es) | Composicion antiarrugas que comprende una asociacion de polimeros tensores de origen sintetico y/o natural y de polimeros dendriticos. | |
ATE326953T1 (de) | Umhüllung kleiner partikel | |
CA2304662A1 (en) | Methods for fabricating polymer-based controlled release preparations | |
DE60008299D1 (de) | Verfahren für die produktion einer in wasser dispersiblen carotenoid-haltigen formulierung | |
ATE286388T1 (de) | Verfahren zur herstellung von nanokapseln des vesikulären typs | |
GB2336110A (en) | Method of manufacturing porous matrix-type controlled release systems using emulsion technique | |
BR9908936A (pt) | Processos para produzir uma preparação de liberação sustentada, e para produzir um pó de polipeptìdeo fisiologicamente ativo, preparação de liberação sustentada, pó de polipeptìdeo fisiologicamente ativo, e, usos do pó polipeptìdeo fisiologicamente ativo, e de um solvente orgânico miscìvel em água e/ou um sal volátil | |
ATE230251T1 (de) | Lipidmembran zusammensetzungen | |
DE69631602D1 (de) | Wässrige dispersionen von polyamiden | |
NO963003L (no) | Fremgangsmåte for fremstilling av en vandig emulsjon med snever dråpestörrelsesfordeling, og anvendelse av en slik emulsjon for fremstilling av en polymerdispersjon | |
RU97107265A (ru) | Способ ароматизации воздуха | |
CA2142445A1 (en) | Injection solutions of azosemide which are ready for injection | |
RU97115747A (ru) | Способ получения микрокапсул с органическим фотохромным соединением для введения их в печатную краску |