DK0673376T3 - Bicykliske pyrimidinforbindelser, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som omfatter dem - Google Patents

Bicykliske pyrimidinforbindelser, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som omfatter dem

Info

Publication number
DK0673376T3
DK0673376T3 DK94902003.6T DK94902003T DK0673376T3 DK 0673376 T3 DK0673376 T3 DK 0673376T3 DK 94902003 T DK94902003 T DK 94902003T DK 0673376 T3 DK0673376 T3 DK 0673376T3
Authority
DK
Denmark
Prior art keywords
pct
processes
preparation
pyrimidine compounds
pharmaceutical agents
Prior art date
Application number
DK94902003.6T
Other languages
Danish (da)
English (en)
Inventor
Gilbert Regnier
Alain Dhainaut
Ghanem Atassi
Alain Pierre
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Application granted granted Critical
Publication of DK0673376T3 publication Critical patent/DK0673376T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK94902003.6T 1992-12-11 1993-12-09 Bicykliske pyrimidinforbindelser, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som omfatter dem DK0673376T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9214913A FR2699176B1 (fr) 1992-12-11 1992-12-11 Nouveaux composés bicycliques de pyrimidine, leur procédé de préparation et les compositions pharmaceutiques les renfermant.

Publications (1)

Publication Number Publication Date
DK0673376T3 true DK0673376T3 (da) 1996-10-07

Family

ID=9436453

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94902003.6T DK0673376T3 (da) 1992-12-11 1993-12-09 Bicykliske pyrimidinforbindelser, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som omfatter dem

Country Status (13)

Country Link
US (1) US5508277A (de)
EP (1) EP0673376B1 (de)
JP (1) JPH08504426A (de)
AT (1) ATE138380T1 (de)
AU (1) AU666422B2 (de)
CA (1) CA2117462A1 (de)
DE (1) DE69302829T2 (de)
DK (1) DK0673376T3 (de)
ES (1) ES2091126T3 (de)
FR (1) FR2699176B1 (de)
GR (1) GR3020330T3 (de)
NZ (1) NZ258595A (de)
WO (1) WO1994013668A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE9110772U1 (de) * 1991-08-30 1991-11-14 Wolf - Geräte GmbH Vertriebsgesellschaft KG, 5240 Betzdorf Gartenschere
FR2699176B1 (fr) * 1992-12-11 1995-03-03 Adir Nouveaux composés bicycliques de pyrimidine, leur procédé de préparation et les compositions pharmaceutiques les renfermant.
US5866702A (en) * 1996-08-02 1999-02-02 Cv Therapeutics, Incorporation Purine inhibitors of cyclin dependent kinase 2
US6794390B2 (en) * 1996-08-02 2004-09-21 Cv Therapeutics, Inc. Purine inhibitors of cyclin dependent kinase 2 & ikappabalpha
WO2003009815A2 (en) 2001-07-25 2003-02-06 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
EP2671508B1 (de) 2005-04-28 2020-09-16 Proteus Digital Health, Inc. Pharma-Informatiksystem
CA2615946A1 (en) 2005-07-22 2007-02-01 Sunesis Pharmaceuticals, Inc. Pyrazolo pyrimidines useful as aurora kinase inhibitors
CA2663377A1 (en) 2006-09-18 2008-03-27 Raptor Pharmaceutical Inc. Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
AU2010216512B2 (en) 2009-02-20 2016-06-30 2-Bbb Medicines B.V. Glutathione-based drug delivery system
CA2756871A1 (en) 2009-03-31 2010-10-07 Arqule, Inc. Substituted heterocyclic compounds
EP2427178B1 (de) 2009-05-06 2023-01-04 Laboratory Skin Care, Inc. Dermale freisetzungszusammensetzung mit wirkstoff-calciumphosphat-partikelkomplexen und anwendungsverfahren
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
WO2023192941A2 (en) * 2022-04-01 2023-10-05 Drexel University Treating cancer with small molecules that inhibit acss-2

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1544419A (en) * 1975-11-19 1979-04-19 Science Union & Cie Purines and pyrazolo-pyrimidines a process for their preparation and pharmaceutical compositions containing them
DE2804416A1 (de) * 1978-02-02 1979-08-09 Boehringer Mannheim Gmbh Neue purin-derivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
US5204353A (en) * 1987-04-07 1993-04-20 Ciba-Geigy Corporation 3-benzyl-3H-1,2,3-triazolo[4,5-d]pyrimidines, compositions thereof, and method of treating epilepsy therewith
CA1338625C (en) * 1988-06-09 1996-10-01 Kyowa Hakko Kogyo Co., Ltd. Tricyclic compounds
EP0363320A3 (de) * 1988-10-06 1991-11-21 Ciba-Geigy Ag Substituierte 9H-Purine
FR2643373B1 (fr) * 1989-01-10 1993-12-31 Adir Cie Nouveaux derives des bisarylalcenes, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
US5256650A (en) * 1989-03-29 1993-10-26 Merrell Dow Pharmaceuticals Inc. Selective adenosine receptor agents
ATE140457T1 (de) * 1989-09-19 1996-08-15 Teijin Ltd Pyrrolo(2,3-d>pyrimidinderivate, verfahren zur herstellung und arzneimittelzusammensetzungen die diese enthalten
ATE139232T1 (de) * 1989-10-11 1996-06-15 Teijin Ltd Bizyklische pyrimidinderivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzung
US5397782A (en) * 1990-06-13 1995-03-14 Janssen Pharmaceutica N.V. Method of treating addiction to alcohol
US5217980A (en) * 1990-07-19 1993-06-08 Janssen Pharmaceutica N.V. Oxazolyl and piperidinyl substituted benimidazolyl compounds
DE69028994T2 (de) * 1990-12-06 1997-04-10 Sony Corp., Tokio/Tokyo Rückgekoppelte klemmschaltung
FR2699176B1 (fr) * 1992-12-11 1995-03-03 Adir Nouveaux composés bicycliques de pyrimidine, leur procédé de préparation et les compositions pharmaceutiques les renfermant.

Also Published As

Publication number Publication date
FR2699176B1 (fr) 1995-03-03
NZ258595A (en) 1996-04-26
US5508277A (en) 1996-04-16
CA2117462A1 (fr) 1994-06-23
GR3020330T3 (en) 1996-09-30
WO1994013668A1 (fr) 1994-06-23
AU5653594A (en) 1994-07-04
DE69302829D1 (de) 1996-06-27
EP0673376A1 (de) 1995-09-27
EP0673376B1 (de) 1996-05-22
ATE138380T1 (de) 1996-06-15
JPH08504426A (ja) 1996-05-14
AU666422B2 (en) 1996-02-08
ES2091126T3 (es) 1996-10-16
FR2699176A1 (fr) 1994-06-17
DE69302829T2 (de) 1996-11-28

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