DK0669129T3 - Ekspanderbare lægemiddelformer med kontrolleret afgivelse af aktivt stof - Google Patents

Ekspanderbare lægemiddelformer med kontrolleret afgivelse af aktivt stof

Info

Publication number
DK0669129T3
DK0669129T3 DK95102074T DK95102074T DK0669129T3 DK 0669129 T3 DK0669129 T3 DK 0669129T3 DK 95102074 T DK95102074 T DK 95102074T DK 95102074 T DK95102074 T DK 95102074T DK 0669129 T3 DK0669129 T3 DK 0669129T3
Authority
DK
Denmark
Prior art keywords
contg
polymer
pref
gps
polymers
Prior art date
Application number
DK95102074T
Other languages
Danish (da)
English (en)
Inventor
Gunther Dr Penners
Klemens Dr Lustig
Joerg Dr Petersen-Von-Gehr
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of DK0669129T3 publication Critical patent/DK0669129T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK95102074T 1994-02-28 1995-02-15 Ekspanderbare lægemiddelformer med kontrolleret afgivelse af aktivt stof DK0669129T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4406424A DE4406424A1 (de) 1994-02-28 1994-02-28 Expandierbare Arzneiformen

Publications (1)

Publication Number Publication Date
DK0669129T3 true DK0669129T3 (da) 2002-02-25

Family

ID=6511366

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95102074T DK0669129T3 (da) 1994-02-28 1995-02-15 Ekspanderbare lægemiddelformer med kontrolleret afgivelse af aktivt stof

Country Status (10)

Country Link
US (2) US5651985A (ja)
EP (1) EP0669129B1 (ja)
JP (1) JP3937464B2 (ja)
AT (1) ATE207741T1 (ja)
CA (1) CA2143500C (ja)
DE (2) DE4406424A1 (ja)
DK (1) DK0669129T3 (ja)
ES (1) ES2166790T3 (ja)
PT (1) PT669129E (ja)
SI (1) SI0669129T1 (ja)

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DE4406424A1 (de) * 1994-02-28 1995-08-31 Bayer Ag Expandierbare Arzneiformen
FR2723536A1 (fr) * 1994-08-11 1996-02-16 Seth Pawan Composition permettant une liberation selective d'un principe actif
US6280745B1 (en) 1997-12-23 2001-08-28 Alliance Pharmaceutical Corp. Methods and compositions for the delivery of pharmaceutical agents and/or the prevention of adhesions
PT936903E (pt) * 1996-09-07 2004-03-31 Gunther Beisel Agente de efeito retardador
JP3825811B2 (ja) * 1997-01-14 2006-09-27 エルティエス ローマン テラピー−ズュステーメ アーゲー 胃腸系での活性物質の制御放出を用いた膨張性胃内貯留治療システム
SE9702533D0 (sv) 1997-07-01 1997-07-01 Astra Ab New oral formulation
IN186245B (ja) 1997-09-19 2001-07-14 Ranbaxy Lab Ltd
US6090411A (en) * 1998-03-09 2000-07-18 Temple University Monolithic tablet for controlled drug release
FR2784583B1 (fr) 1998-10-16 2002-01-25 Synthelabo Composition pharmaceutique a residence gastrique et a liberation controlee
DE19920833A1 (de) * 1999-05-06 2000-11-16 Lohmann Therapie Syst Lts Gastroretentives System mit quellbaren Polymeren
FR2797185B1 (fr) * 1999-08-06 2001-10-26 Galenix Dev Composition pharmaceutique flottante comprenant une phase active et une phase non active
IL133196A0 (en) 1999-11-29 2001-03-19 Yissum Res Dev Co Gastroretentive controlled release pharmaceutical dosage forms
EP1118321A1 (fr) * 2000-01-14 2001-07-25 Ucb, S.A. Compositions pharmaceutiques solides pour la libération contrôlée de substances actives
IL150850A0 (en) * 2000-02-10 2003-02-12 Bpsi Holdings Inc Enteric coating compositions containing acrylic resin
BR0108958A (pt) * 2000-03-03 2003-09-30 Ranbaxy Lab Ltd Sistema de liberação controlada, administrado oralmente, para administração diária de ciprofloxacina
DE10014588A1 (de) 2000-03-27 2001-10-04 Basf Ag Wirkstoffhaltige Schwimmformen enthaltend Polyvinylacetat und Polyvinylpyrrolidon, deren Verwendung und Herstellung
DE10031043A1 (de) * 2000-06-26 2002-02-14 Bayer Ag Retardzubereitungen von Chinolonantibiotika und Verfahren zu ihrer Herstellung
EP1245227A1 (en) 2001-03-31 2002-10-02 Jagotec Ag A pharmaceutical tablet system that floats in the stomach for programmed release of active substance and process of producing buoyant material contained in same
AU2008255254B2 (en) * 2001-03-31 2010-12-09 Jagotec Ag A pharmaceutical tablet system that floats on gastric fluid for multipulse release of active substance and respective processes of producing same and a cup-shaped envelope of same
PL370793A1 (en) * 2001-07-04 2005-05-30 Sun Pharmaceutical Industries Limited Gastric retention controlled drug delivery system
US20040219186A1 (en) * 2001-08-16 2004-11-04 Ayres James W. Expandable gastric retention device
BR0117123A (pt) * 2001-08-16 2004-09-28 Oregon State Dispositivo de retenção gástrica expansìvel
US20030104052A1 (en) * 2001-10-25 2003-06-05 Bret Berner Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract
US20030091630A1 (en) * 2001-10-25 2003-05-15 Jenny Louie-Helm Formulation of an erodible, gastric retentive oral dosage form using in vitro disintegration test data
US7612112B2 (en) 2001-10-25 2009-11-03 Depomed, Inc. Methods of treatment using a gastric retained gabapentin dosage
TWI312285B (en) 2001-10-25 2009-07-21 Depomed Inc Methods of treatment using a gastric retained gabapentin dosage
CA2409552A1 (en) 2001-10-25 2003-04-25 Depomed, Inc. Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract
US20030152622A1 (en) * 2001-10-25 2003-08-14 Jenny Louie-Helm Formulation of an erodible, gastric retentive oral diuretic
EP1509208A1 (en) * 2002-02-04 2005-03-02 Ranbaxy Laboratories Limited Hydrodynamically balancing oral drug delivery system with biphasic release
US7923032B2 (en) * 2002-11-26 2011-04-12 Seacoast Neuroscience, Inc. Buoyant polymer particles for delivery of therapeutic agents to the central nervous system
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TW200533391A (en) 2004-03-25 2005-10-16 Sun Pharmaceutical Ind Ltd Gastric retention drug delivery system
US20050220873A1 (en) * 2004-04-02 2005-10-06 Chien-Hsuan Han Pharmaceutical dosage forms having immediate and controlled release properties that contain a GABAB receptor agonist
US20050220863A1 (en) * 2004-04-02 2005-10-06 Chien-Hsuan Han Pharmaceutical dosage forms having controlled release properties that contain a GABAB receptor agonist
US20050226927A1 (en) * 2004-04-02 2005-10-13 Impax Laboratories, Inc. Pharmaceutical dosage forms having immediate release and/or controlled release properties that contain a GABAB receptor agonist
US8007827B2 (en) * 2004-04-02 2011-08-30 Impax Laboratories, Inc. Pharmaceutical dosage forms having immediate release and/or controlled release properties
DE102004023069A1 (de) 2004-05-11 2005-12-08 Bayer Healthcare Ag Neue Darreichungsformen des PDE 5-Inhibitors Vardenafil
US20050287212A1 (en) * 2004-06-28 2005-12-29 Liang-Chang Dong Oral delivery system comprising a drug/polymer complex
US20090176882A1 (en) 2008-12-09 2009-07-09 Depomed, Inc. Gastric retentive gabapentin dosage forms and methods for using same
CA2647487C (en) * 2006-03-29 2014-10-21 Electronic Dietary Foods Inc. Ingestible implement for weight control
US9579227B2 (en) 2006-03-29 2017-02-28 Eat Little Inc. Ingestible implement for weight control
US8426466B2 (en) 2006-05-22 2013-04-23 Nexus Pharma, Inc. Compositions and methods for enhancing active agent absorption
US8889184B2 (en) * 2006-09-07 2014-11-18 Losan Pharma Gmbh Particulate form of a pharmaceutical composition which is easy to swallow
WO2009008873A1 (en) * 2007-07-06 2009-01-15 Basf Corporation A gastroretentive composition on the basis of a water-soluble reaction product from a vinyl group- containing precursor
CA2694602A1 (en) * 2007-07-27 2009-02-05 Depomed, Inc. Pulsatile gastric retentive dosage forms
US20090036414A1 (en) * 2007-08-02 2009-02-05 Mutual Pharmaceutical Company, Inc. Mesalamine Formulations
US20110171275A1 (en) * 2007-08-20 2011-07-14 Team Academy Of Pharmaceutical Science Gastroretentive drug delivery system, preparation method and use thereof
MX340249B (es) 2008-08-15 2016-07-01 Depomed Inc Composiciones farmacéuticas retentivas gástricas para tratamiento y prevención de transtornos del sistema nervioso central (cns).
KR20110042366A (ko) 2008-08-18 2011-04-26 팀 아카데미 오브 파마슈티컬 사이언스 위장체류 약물 전달 시스템, 제작 방법 및 그것들의 사용
EP2210585A1 (en) 2009-01-16 2010-07-28 Exelgyn SPRM pharmaceutical compositions methods of treatment using them
US8858963B1 (en) 2011-05-17 2014-10-14 Mallinckrodt Llc Tamper resistant composition comprising hydrocodone and acetaminophen for rapid onset and extended duration of analgesia
US8658631B1 (en) 2011-05-17 2014-02-25 Mallinckrodt Llc Combination composition comprising oxycodone and acetaminophen for rapid onset and extended duration of analgesia
WO2013051036A1 (en) 2011-10-03 2013-04-11 Council Of Scientific & Industrial Research Use of pharmaceutical composition for gastroretentive sustained and pulsatile drug delivery system
US20130143867A1 (en) 2011-12-02 2013-06-06 Sychroneuron Inc. Acamprosate formulations, methods of using the same, and combinations comprising the same
JP2016520653A (ja) 2013-06-05 2016-07-14 シンクロニューロン インコーポレイテッド アカンプロサート製剤、それを用いる方法、およびそれを含む合剤
FR3014692B1 (fr) * 2013-12-18 2016-01-29 Ethypharm Sa Compositions pharmaceutiques orales a retention gastrique.
PL235144B1 (pl) 2014-06-03 2020-06-01 Univ Medyczny Im Piastow Slaskich We Wroclawiu Sposób wytwarzania tabletki flotacyjnej o przedłużonym oddziaływaniu substancji leczniczych z błoną śluzową żołądka oraz kompozycja farmaceutyczna
US20170266112A1 (en) 2014-06-11 2017-09-21 Massachusetts Institute Of Technology Residence structures and related methods
CN106714893B (zh) 2014-06-11 2021-01-01 麻省理工学院 自组装的驻留装置及相关方法
WO2017070612A1 (en) * 2015-10-23 2017-04-27 Lyndra, Inc. Gastric residence systems for sustained release of therapeutic agents and methods of use thereof
CN108697649A (zh) 2015-12-08 2018-10-23 林德拉有限公司 用于胃驻留系统的几何构型
BR112019003811A2 (pt) 2016-08-26 2019-05-21 Exciva Ug (Haftungsbeschränkt) composição farmacêutica, método para aumentar os níveis plasmáticos de antagonista do receptor de nmda em um sujeito que precisa do mesmo, método para tratar uma doença ou transtorno em um sujeito que precisa do mesmo e uso da composição
CA3038557A1 (en) 2016-09-30 2018-04-05 Lyndra, Inc. Gastric residence systems for sustained delivery of adamantane-class drugs
CN110996906A (zh) 2017-06-09 2020-04-10 林德拉有限公司 具有调节释放速度的膜的胃驻留系统
WO2023214018A1 (en) * 2022-05-06 2023-11-09 Galenix Innovations Gastro-retentive swellable sustained release composition

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Also Published As

Publication number Publication date
US5651985A (en) 1997-07-29
JP3937464B2 (ja) 2007-06-27
CA2143500A1 (en) 1995-08-29
CA2143500C (en) 2007-04-24
DE4406424A1 (de) 1995-08-31
ATE207741T1 (de) 2001-11-15
ES2166790T3 (es) 2002-05-01
EP0669129A2 (de) 1995-08-30
EP0669129A3 (de) 1995-11-22
JPH0840879A (ja) 1996-02-13
SI0669129T1 (en) 2002-04-30
US6306439B1 (en) 2001-10-23
PT669129E (pt) 2002-03-28
DE59509765D1 (de) 2001-12-06
EP0669129B1 (de) 2001-10-31

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