DK0582481T3 - Fremstilling af 19-norvitamin D forbindelser - Google Patents

Fremstilling af 19-norvitamin D forbindelser

Info

Publication number
DK0582481T3
DK0582481T3 DK93306211.9T DK93306211T DK0582481T3 DK 0582481 T3 DK0582481 T3 DK 0582481T3 DK 93306211 T DK93306211 T DK 93306211T DK 0582481 T3 DK0582481 T3 DK 0582481T3
Authority
DK
Denmark
Prior art keywords
ring
end product
desired end
isomer
diol
Prior art date
Application number
DK93306211.9T
Other languages
Danish (da)
English (en)
Inventor
Heinrich K Schnoes
Hector F Deluca
Fariba Aria
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Application granted granted Critical
Publication of DK0582481T3 publication Critical patent/DK0582481T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK93306211.9T 1992-08-07 1993-08-05 Fremstilling af 19-norvitamin D forbindelser DK0582481T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US92682992A 1992-08-07 1992-08-07

Publications (1)

Publication Number Publication Date
DK0582481T3 true DK0582481T3 (da) 1996-07-01

Family

ID=25453770

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93306211.9T DK0582481T3 (da) 1992-08-07 1993-08-05 Fremstilling af 19-norvitamin D forbindelser

Country Status (8)

Country Link
US (6) US5430196A (fr)
EP (1) EP0582481B1 (fr)
JP (1) JP3568219B2 (fr)
KR (1) KR100236252B1 (fr)
AT (1) ATE138908T1 (fr)
AU (1) AU666563B2 (fr)
DE (1) DE69300626T2 (fr)
DK (1) DK0582481T3 (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU666563B2 (en) * 1992-08-07 1996-02-15 Wisconsin Alumni Research Foundation Preparation of 19-nor-vitamin D compounds
US5449668A (en) * 1993-06-04 1995-09-12 Duphar International Research B.V. Vitamin D compounds and method of preparing these compounds
PT707566E (pt) * 1993-07-09 2000-09-29 Theramex Novos analogos estruturais da vitamina d
CA2206876A1 (fr) * 1994-11-21 1996-05-30 Wisconsin Alumni Research Foundation Composes du type 18,19-dinor-vitamine d
US5976159A (en) * 1995-02-24 1999-11-02 Heartport, Inc. Surgical clips and methods for tissue approximation
ES2144183T3 (es) * 1995-10-30 2000-06-01 Hoffmann La Roche 1-alfa,26-dihidroxi-d-homo-vitamina d3.
JP2000503641A (ja) 1995-12-29 2000-03-28 エイ・アンド・ディ・アッセイ・インコーポレイテッド 標識ビタミンｄ化合物およびその使用
US5919986A (en) * 1997-10-17 1999-07-06 Hoffmann-La Roche Inc. D-homo vitamin D3 derivatives
US6043385A (en) * 1997-12-16 2000-03-28 Hoffman-La Roche Inc. Vitamin D derivatives
US7311703B2 (en) * 2003-07-18 2007-12-25 Vivant Medical, Inc. Devices and methods for cooling microwave antennas
US20060200169A1 (en) * 2005-03-07 2006-09-07 Kevin Sniffin Specimen retrieval apparatus and method of use
WO2007038094A1 (fr) * 2005-09-22 2007-04-05 Wisconsin Alumni Research Foundation 19,23,24,25,26,27-hexanor-1alpha-hydroxyvitamine d3
WO2009086440A1 (fr) * 2007-12-28 2009-07-09 Wisconsin Alumni Research Foundation Dérivés d'analogues de vitamine d 2-méthylène-20-méthyl-19,24,25,26,27-pentanor
DE102008022520A1 (de) * 2008-05-07 2009-11-12 Bayer Animal Health Gmbh Feste Arzneimittelformulierung mit verzögerter Freisetzung
WO2010009879A2 (fr) 2008-07-22 2010-01-28 Azad Pharmaceutical Ingredients Ag Procédés de production de paricalcitol
CN102341110B (zh) 2009-01-27 2017-04-12 博格有限责任公司 用于减轻与化疗有关的副作用的维生素d3及其类似物
PL216135B1 (pl) 2009-08-07 2014-03-31 Inst Farmaceutyczny Nowe syntony i ich zastosowanie do otrzymywania pochodnych 19-nor witamin D
CN102655869B (zh) 2009-08-14 2016-08-10 博格有限责任公司 用于治疗脱发的维生素d3及其类似物
EP2634171B8 (fr) * 2010-10-25 2016-01-13 Teijin Pharma Limited Dérivé de 23-yne-vitamine d3
JP6608810B2 (ja) 2013-05-29 2019-11-20 バーグ エルエルシー ビタミンｄを使用する化学療法誘発性脱毛症の予防又は軽減

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8904154D0 (en) * 1989-02-23 1989-04-05 Leo Pharm Prod Ltd Chemical compounds
US5246925A (en) * 1989-03-09 1993-09-21 Wisconsin Alumni Research Foundation 19-nor-vitamin D compounds for use in treating hyperparathyroidism
CA1333616C (fr) * 1989-03-09 1994-12-20 Hector F. Deluca Composes de type 19-nor-vitamine d
US5321018A (en) * 1989-03-09 1994-06-14 Wisconsin Alumni Research Foundation Use of 1α-hydroxylated-19-nor-vitamin D compounds to treat psoriasis
NZ232734A (en) * 1989-03-09 1991-11-26 Wisconsin Alumni Res Found 19-nor vitamin d derivatives and pharmaceutical compositions
GB8914963D0 (en) * 1989-06-29 1989-08-23 Leo Pharm Prod Ltd Chemical compounds
US5185150A (en) * 1990-08-24 1993-02-09 Wisconsin Alumni Research Fdn. Cosmetic compositions containing 19-nor-vitamin D compounds
US5459136A (en) * 1990-08-24 1995-10-17 Wisconsin Alumni Research Foundation Methods using vitamin D compounds for improvement of skin conditions
AU649057B2 (en) * 1990-08-24 1994-05-12 Wisconsin Alumni Research Foundation Methods and compositions containing vitamin D compounds for improvement of skin conditions
EP0474517B1 (fr) * 1990-09-07 1998-11-18 Wisconsin Alumni Research Foundation Nouvelle utilisation de composés 1-alpha-hydroxylés de la 19-nor vitamine D pour traiter le psoriasis
US5086191A (en) * 1991-05-28 1992-02-04 Wisconsin Alumni Research Foundation Intermediates for the synthesis of 19-nor vitamin D compounds
AU650751B2 (en) * 1991-05-28 1994-06-30 Wisconsin Alumni Research Foundation Novel synthesis of 19-nor vitamin D compounds
DE4220757A1 (de) * 1992-06-24 1994-01-05 Schering Ag Derivate in der Vitamin D-Reihe mit Modifikationen in der 20-Position, Verfahren zu ihrer Herstellung, Zwischenprodukte für dieses Verfahren, diese Derivate enthaltende pharmazeutische Präparate sowie deren Verwendung zur Herstellung von Arzneimitteln
AU666563B2 (en) * 1992-08-07 1996-02-15 Wisconsin Alumni Research Foundation Preparation of 19-nor-vitamin D compounds
IL107185A (en) * 1992-10-06 1998-02-22 Schering Ag History of 52-carboxylic acid, processes for their preparation and pharmaceutical preparations containing them

Also Published As

Publication number Publication date
ATE138908T1 (de) 1996-06-15
JPH06172302A (ja) 1994-06-21
EP0582481A1 (fr) 1994-02-09
AU666563B2 (en) 1996-02-15
US5856536A (en) 1999-01-05
US5525745A (en) 1996-06-11
US5616744A (en) 1997-04-01
US5599958A (en) 1997-02-04
DE69300626T2 (de) 2009-09-10
AU4444793A (en) 1994-02-10
JP3568219B2 (ja) 2004-09-22
EP0582481B1 (fr) 1995-10-11
US5488183A (en) 1996-01-30
US5430196A (en) 1995-07-04
DE69300626D1 (de) 1996-07-11
KR100236252B1 (ko) 1999-12-15
KR940003910A (ko) 1994-03-14

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