DK0516851T3 - Fysiologisk aktiv substans, der er i stand til at gennemtrænge en biomembran - Google Patents
Fysiologisk aktiv substans, der er i stand til at gennemtrænge en biomembranInfo
- Publication number
- DK0516851T3 DK0516851T3 DK91905340.5T DK91905340T DK0516851T3 DK 0516851 T3 DK0516851 T3 DK 0516851T3 DK 91905340 T DK91905340 T DK 91905340T DK 0516851 T3 DK0516851 T3 DK 0516851T3
- Authority
- DK
- Denmark
- Prior art keywords
- biomembrane
- permeating
- active substance
- physiologically active
- substance capable
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
- C07D207/267—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C233/63—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/70—Enkephalins
- C07K14/702—Enkephalins with at least 1 amino acid in D-form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/56—Ring systems containing bridged rings
- C07C2603/58—Ring systems containing bridged rings containing three rings
- C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
- C07C2603/74—Adamantanes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5011690 | 1990-02-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0516851T3 true DK0516851T3 (da) | 1996-07-15 |
Family
ID=12850141
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK95105215T DK0668290T3 (da) | 1990-02-28 | 1991-02-27 | Fysiologisk aktiv substans, som er i stand til at gennemtrænge biomembranen |
DK91905340.5T DK0516851T3 (da) | 1990-02-28 | 1991-02-27 | Fysiologisk aktiv substans, der er i stand til at gennemtrænge en biomembran |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK95105215T DK0668290T3 (da) | 1990-02-28 | 1991-02-27 | Fysiologisk aktiv substans, som er i stand til at gennemtrænge biomembranen |
Country Status (5)
Country | Link |
---|---|
EP (2) | EP0668290B1 (de) |
CA (1) | CA2076849A1 (de) |
DE (2) | DE69130489T2 (de) |
DK (2) | DK0668290T3 (de) |
WO (1) | WO1991013081A1 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1264129B1 (it) * | 1993-04-09 | 1996-09-16 | Codev S A | Peptidi ad attivita' immunomodulatoria derivati da frammenti di leucochinina |
US5973128A (en) * | 1996-11-22 | 1999-10-26 | The Hospital For Sick Children Research And Development Lp | Glycolipid mimics and methods of use thereof |
US8415354B2 (en) | 2004-04-29 | 2013-04-09 | Abbott Laboratories | Methods of use of inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme |
US20100222316A1 (en) | 2004-04-29 | 2010-09-02 | Abbott Laboratories | Inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme |
US7880001B2 (en) | 2004-04-29 | 2011-02-01 | Abbott Laboratories | Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme |
CN103242192B (zh) | 2005-01-05 | 2016-05-04 | Abbvie公司 | 11-β-羟甾类脱氢酶1型酶的抑制剂 |
US20090192198A1 (en) | 2005-01-05 | 2009-07-30 | Abbott Laboratories | Inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme |
WO2006074330A2 (en) | 2005-01-05 | 2006-07-13 | Abbott Laboratories | Inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme |
US8198331B2 (en) | 2005-01-05 | 2012-06-12 | Abbott Laboratories | Inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme |
JP5736098B2 (ja) | 2007-08-21 | 2015-06-17 | アッヴィ・インコーポレイテッド | 中枢神経系障害を治療するための医薬組成物 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SU1179997A1 (ru) * | 1973-02-28 | 1985-09-23 | Ордена Трудового Красного Знамени Институт Органического Синтеза Ан Латсср | Средство дл лечени паркинсонизма "глудантан |
JPS5143769A (en) * | 1974-10-14 | 1976-04-14 | Asahi Chemical Ind | 11 beeta dd arabinofuranoshirushitoshinjudotaino seizoho |
JPS5919557B2 (ja) * | 1979-05-02 | 1984-05-07 | ヤマサ醤油株式会社 | N↑6−置換コルジセピン誘導体およびその製造法 |
US4273704A (en) * | 1979-12-03 | 1981-06-16 | G. D. Searle & Co. | N-Adamantane-substituted tetrapeptide amides |
FR2572399B1 (fr) * | 1984-10-31 | 1987-01-16 | Panmedica Sa | Nouveaux derives de l'adamantanamine, leurs procedes de preparation et medicaments les contenant |
NO170884C (no) * | 1986-08-18 | 1992-12-23 | Hoffmann La Roche | Analogifremgangsmaate ved fremstilling av terapeutisk aktive pyrimidinderivater |
JPH0717655B2 (ja) * | 1987-05-27 | 1995-03-01 | 三共株式会社 | 経口用セフアロスポリン化合物 |
-
1991
- 1991-02-27 EP EP95105215A patent/EP0668290B1/de not_active Expired - Lifetime
- 1991-02-27 CA CA002076849A patent/CA2076849A1/en not_active Abandoned
- 1991-02-27 DK DK95105215T patent/DK0668290T3/da active
- 1991-02-27 DE DE69130489T patent/DE69130489T2/de not_active Expired - Fee Related
- 1991-02-27 DE DE69120397T patent/DE69120397T2/de not_active Expired - Fee Related
- 1991-02-27 WO PCT/JP1991/000256 patent/WO1991013081A1/ja active IP Right Grant
- 1991-02-27 EP EP91905340A patent/EP0516851B1/de not_active Expired - Lifetime
- 1991-02-27 DK DK91905340.5T patent/DK0516851T3/da active
Also Published As
Publication number | Publication date |
---|---|
EP0516851A4 (en) | 1993-06-09 |
EP0668290B1 (de) | 1998-11-11 |
EP0516851B1 (de) | 1996-06-19 |
EP0668290A1 (de) | 1995-08-23 |
CA2076849A1 (en) | 1991-08-29 |
DK0668290T3 (da) | 1999-07-26 |
DE69130489T2 (de) | 1999-05-12 |
DE69120397T2 (de) | 1996-11-07 |
WO1991013081A1 (fr) | 1991-09-05 |
DE69120397D1 (de) | 1996-07-25 |
DE69130489D1 (de) | 1998-12-17 |
EP0516851A1 (de) | 1992-12-09 |
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