DK0462194T3 - Fibroblast growth factor (FGF) -based stabilized compositions - Google Patents

Fibroblast growth factor (FGF) -based stabilized compositions

Info

Publication number
DK0462194T3
DK0462194T3 DK90904852.2T DK90904852T DK0462194T3 DK 0462194 T3 DK0462194 T3 DK 0462194T3 DK 90904852 T DK90904852 T DK 90904852T DK 0462194 T3 DK0462194 T3 DK 0462194T3
Authority
DK
Denmark
Prior art keywords
fgf
growth factor
fibroblast growth
stabilized compositions
tissular
Prior art date
Application number
DK90904852.2T
Other languages
Danish (da)
Inventor
Denis Barritault
Jacqueline Jozefonvicz
Faouzi Slaoui
Michele Tardieu
Jean-Pierre Caruelle
Jose Courty
Original Assignee
Therapeutiques Substitutives
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9379523&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0462194(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Therapeutiques Substitutives filed Critical Therapeutiques Substitutives
Application granted granted Critical
Publication of DK0462194T3 publication Critical patent/DK0462194T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1825—Fibroblast growth factor [FGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Agents having a cellular and tissular regenerating activity consisting of functionalized substituted dextrans, stabilized compositions containing said agents associated with at least one fibroblast growth factor (FGFs) such as a FGF acid and/or a basic FGF and/or a derivative and/or an analogue and/or a fragment of these disclosing a biological activity and their $i(in vitro) applications such as storing FGFs and cellular cultures and $i(in vivo) applications as a therapeutic agent, in particular for healing and tissular regeneration or as a cosmetic agent.
DK90904852.2T 1989-03-09 1990-03-09 Fibroblast growth factor (FGF) -based stabilized compositions DK0462194T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8903086A FR2644066B1 (en) 1989-03-09 1989-03-09 STABILIZED COMPOSITIONS COMPRISING FGFS, PROCESS FOR OBTAINING THEM AND THERAPEUTIC, SURGICAL AND COSMETOLOGICAL APPLICATIONS

Publications (1)

Publication Number Publication Date
DK0462194T3 true DK0462194T3 (en) 1994-09-19

Family

ID=9379523

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90904852.2T DK0462194T3 (en) 1989-03-09 1990-03-09 Fibroblast growth factor (FGF) -based stabilized compositions

Country Status (10)

Country Link
EP (1) EP0462194B1 (en)
JP (1) JP3236916B2 (en)
AT (1) ATE106743T1 (en)
AU (1) AU5283890A (en)
CA (1) CA2048638C (en)
DE (1) DE69009748T2 (en)
DK (1) DK0462194T3 (en)
ES (1) ES2057544T3 (en)
FR (1) FR2644066B1 (en)
WO (1) WO1990010456A1 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5202311A (en) * 1988-08-19 1993-04-13 Children's Medical Center Corporation Stabilized fgf composition
US5482929A (en) * 1991-12-26 1996-01-09 Kaken Pharmaceutical Co., Ltd. Composition of stabilized fibroblast growth factor
FR2718024B1 (en) * 1994-03-30 1996-06-21 Paris Val Marne Universite Medicine and pharmaceutical composition for the treatment of inflammation.
FR2718025B1 (en) * 1994-03-30 1996-06-21 Paris Val Marne Universite Medicament and pharmaceutical composition for the treatment of lesions of the nervous system.
FR2718026B1 (en) * 1994-03-30 1997-01-17 Paris Val Marne Universite Medicine and pharmaceutical composition for the treatment of muscles.
FR2718023B1 (en) * 1994-03-30 1996-08-14 Paris Val Marne Universite Medicament and pharmaceutical composition for the treatment of lesions of the digestive tract.
FR2772382B1 (en) * 1997-12-11 2000-03-03 Solutions DEXTRAN DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATIONS AS MEDICINES WITH SPECIFIC BIOLOGICAL ACTION
FR2781485B1 (en) 1998-07-21 2003-08-08 Denis Barritault BIOCOMPATIBLE POLYMERS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM
FR2781375A1 (en) * 1998-07-21 2000-01-28 Denis Barritault Use of (bio)polymer of heparin-binding growth factor protector and potentiator family to prepare medicament for treating and/or preventing fibrosis
EP1107791B8 (en) * 1998-09-04 2007-11-07 Scios Inc. Hydrogel compositions for the controlled release administration of growth factors
FR2794649B1 (en) 1999-06-11 2003-04-11 Solutions BIOMATERIAL BASED ON AN INSOLUBILIZED DEXTRAN DERIVATIVE AND A GROWTH FACTOR, METHOD FOR PREPARING SAME AND ITS APPLICATIONS
FR2794976B1 (en) * 1999-06-16 2004-05-07 Solutions PHARMACEUTICAL COMPOSITIONS WITH HEALING OR ANTI-COMPLEMENTARY ACTION COMPRISING A DEXTRANE DERIVATIVE
JP5740301B2 (en) 2008-03-27 2015-06-24 パーデュー・リサーチ・ファウンデーションＰｕｒｄｕｅ Ｒｅｓｅａｒｃｈ Ｆｏｕｎｄａｔｉｏｎ Collagen-binding synthetic peptidoglycan, preparation and use method
AU2012258706B2 (en) 2011-05-24 2017-05-18 Symic OA ApS Hyaluronic acid-binding synthetic peptidoglycans, preparation, and methods of use
CA2903450A1 (en) 2013-03-15 2014-09-18 Symic Biomedical, Inc. Extracellular matrix-binding synthetic peptidoglycans
US10772931B2 (en) 2014-04-25 2020-09-15 Purdue Research Foundation Collagen binding synthetic peptidoglycans for treatment of endothelial dysfunction
US10792106B2 (en) 2016-10-28 2020-10-06 Covidien Lp System for calibrating an electromagnetic navigation system
KR20200026263A (en) 2017-07-07 2020-03-10 시믹 아이피, 엘엘씨 Synthetic bioconjugates
US11596399B2 (en) 2021-06-23 2023-03-07 Covidien Lp Anvil buttress attachment for surgical stapling apparatus

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ235556A (en) * 1986-11-05 1991-06-25 Ethicon Inc Breast milk substitute containing recombinant human egf

Also Published As

Publication number Publication date
WO1990010456A1 (en) 1990-09-20
EP0462194A1 (en) 1991-12-27
EP0462194B1 (en) 1994-06-08
CA2048638C (en) 2002-06-11
DE69009748D1 (en) 1994-07-14
JP3236916B2 (en) 2001-12-10
JPH04505756A (en) 1992-10-08
ES2057544T3 (en) 1994-10-16
FR2644066B1 (en) 1994-05-13
ATE106743T1 (en) 1994-06-15
AU5283890A (en) 1990-10-09
CA2048638A1 (en) 1990-09-10
DE69009748T2 (en) 1994-09-22
FR2644066A1 (en) 1990-09-14

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