DK0411534T3 - Derivater af 1,2,3,4-tetrahydro-9-acridinamin - Google Patents

Derivater af 1,2,3,4-tetrahydro-9-acridinamin

Info

Publication number
DK0411534T3
DK0411534T3 DK90114586.2T DK90114586T DK0411534T3 DK 0411534 T3 DK0411534 T3 DK 0411534T3 DK 90114586 T DK90114586 T DK 90114586T DK 0411534 T3 DK0411534 T3 DK 0411534T3
Authority
DK
Denmark
Prior art keywords
acridinamine
tetrahydro
derivatives
agents
cerebral
Prior art date
Application number
DK90114586.2T
Other languages
Danish (da)
English (en)
Inventor
Jeffrey Alan Kester
Colin Granger
Moos Walter Hamilton
Anthony Jerome Thomas
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Application granted granted Critical
Publication of DK0411534T3 publication Critical patent/DK0411534T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C07D219/10—Nitrogen atoms attached in position 9
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Water Treatment By Electricity Or Magnetism (AREA)
DK90114586.2T 1989-07-31 1990-07-30 Derivater af 1,2,3,4-tetrahydro-9-acridinamin DK0411534T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/387,722 US4999430A (en) 1989-07-31 1989-07-31 Derivatives of 1,2,3,4-tetrahydro-9-acrisinamine

Publications (1)

Publication Number Publication Date
DK0411534T3 true DK0411534T3 (da) 1995-07-24

Family

ID=23531113

Family Applications (2)

Application Number Title Priority Date Filing Date
DK94112223T DK0628548T3 (da) 1989-07-31 1990-07-30 1,2,3,4-Tetraydro-acridinamin-derivater
DK90114586.2T DK0411534T3 (da) 1989-07-31 1990-07-30 Derivater af 1,2,3,4-tetrahydro-9-acridinamin

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK94112223T DK0628548T3 (da) 1989-07-31 1990-07-30 1,2,3,4-Tetraydro-acridinamin-derivater

Country Status (17)

Country Link
US (1) US4999430A (fr)
EP (2) EP0628548B1 (fr)
JP (1) JP2930245B2 (fr)
KR (1) KR910002802A (fr)
AT (2) ATE186908T1 (fr)
AU (1) AU5994590A (fr)
CA (1) CA2022297C (fr)
DE (2) DE69033369T2 (fr)
DK (2) DK0628548T3 (fr)
ES (2) ES2068955T3 (fr)
FI (1) FI903752A0 (fr)
GR (1) GR3032539T3 (fr)
IE (1) IE66823B1 (fr)
NO (1) NO903359L (fr)
NZ (1) NZ234672A (fr)
PT (1) PT94849A (fr)
ZA (1) ZA905978B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL85741A (en) * 1987-03-17 1996-05-14 Hoechst Roussel Pharma Transformed Tetra-Hydroacridines Process for their preparation and pharmaceutical preparations containing A-amino-Tetra-Transformed Hydroacridines
FR2640508B1 (fr) * 1988-12-19 1994-07-01 Dietlin Francois Nouvelles compositions et nouveaux produits pharmaceutiques assurant la regeneration de leucocytes et leur emploi pour le traitement du syndrome immuno-deficitaire
JP2546919B2 (ja) * 1989-11-08 1996-10-23 三菱化学株式会社 ９ーアシルアミノテトラヒドロアクリジン誘導体
CA2029497C (fr) * 1989-11-08 2002-06-04 Kunihiro Ninomiya (Deceased) Derive 4-acylaminopyridine
US5179100A (en) * 1992-03-09 1993-01-12 Hoechst-Roussel Pharmaceuticals Inc. 4,5-dihydropyrazolo[3,4-a]acridines
US5422350A (en) * 1992-09-10 1995-06-06 Warner-Lambert Company Nitrogen substituted acridine and cytochrome P450 inhibitors and methods of use
US5466696A (en) * 1992-09-10 1995-11-14 Warner Lambert Company Tacrine and cytochrome P450 oxidase inhibitors and methods of use
HU213107B (en) * 1994-02-23 1997-02-28 Egyt Gyogyszervegyeszeti Gyar Process for producing acetic acid derivatives and pharmaceutical compositions containing them
GB9716879D0 (en) * 1997-08-08 1997-10-15 Shire Int Licensing Bv Treatment of attention deficit disorders
US6218383B1 (en) 1998-08-07 2001-04-17 Targacept, Inc. Pharmaceutical compositions for the prevention and treatment of central nervous system disorders
ES2168926B1 (es) * 1999-12-14 2003-10-16 Prous Science S A Derivados de ciclopenta- ciclohexa- y ciclohepta (b)quinoleina, procedimiento para su fabricacion, utilizacion y composicion farmaceutica correspondiente.
EP1779867A4 (fr) * 2004-07-01 2009-12-02 Eisai R&D Man Co Ltd Promoteur de la régénérescence nerveuse
CN1315810C (zh) * 2004-08-30 2007-05-16 北京理工大学 哌嗪桥联他克林双体衍生物及其合成方法
US20080188510A1 (en) * 2005-05-23 2008-08-07 Eisai R & D Management Co., Ltd. Novel methods using zonisamide
BR112012014022A2 (pt) 2009-12-11 2017-04-04 Genecode As composto, composição, dispositivo médico e método ex vivo para modulação do crescimento de um neurônico
BR112012019923A2 (pt) 2010-02-09 2016-08-09 Univ Johns Hopkins métodos e composições para melhorar a função cognitiva
WO2014078568A1 (fr) 2012-11-14 2014-05-22 The Johns Hopkins University Méthodes et compositions pour le traitement de la schizophrénie
DK2968220T3 (da) 2013-03-15 2021-06-14 Agenebio Inc Fremgangsmåder og sammensætninger til forbedring af kognitiv funktion
WO2014144663A1 (fr) 2013-03-15 2014-09-18 The Johns Hopkins University Procédés et compositions pour améliorer la fonction cognitive
CA2986598C (fr) 2015-05-22 2023-09-26 Agenebio, Inc. Compositions pharmaceutiques de levetiracetam a liberation prolongee

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3889302T2 (de) * 1987-12-03 1994-10-20 Mitsubishi Chem Ind 9-(Acylamino)tetrahydroacridinderivate und wahrnehmungssteigernde Mittel davon als aktiver Wirkstoff.

Also Published As

Publication number Publication date
GR3032539T3 (en) 2000-05-31
DE69033369T2 (de) 2000-05-11
EP0411534A3 (en) 1991-06-05
ES2068955T3 (es) 1995-05-01
ATE119885T1 (de) 1995-04-15
FI903752A0 (fi) 1990-07-27
CA2022297A1 (fr) 1991-02-01
AU5994590A (en) 1991-01-31
PT94849A (pt) 1991-04-18
EP0628548B1 (fr) 1999-11-24
IE66823B1 (en) 1996-02-07
CA2022297C (fr) 2001-09-18
DK0628548T3 (da) 2000-05-08
ZA905978B (en) 1992-04-29
ATE186908T1 (de) 1999-12-15
NZ234672A (en) 1991-11-26
KR910002802A (ko) 1991-02-26
IE902751A1 (en) 1991-02-27
ES2141787T3 (es) 2000-04-01
NO903359D0 (no) 1990-07-30
DE69017789T2 (de) 1995-07-13
EP0411534B1 (fr) 1995-03-15
EP0411534A2 (fr) 1991-02-06
EP0628548A1 (fr) 1994-12-14
DE69017789D1 (de) 1995-04-20
NO903359L (no) 1991-02-01
JPH0366670A (ja) 1991-03-22
JP2930245B2 (ja) 1999-08-03
US4999430A (en) 1991-03-12
DE69033369D1 (de) 1999-12-30

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