DK0398460T3 - Anvendelse af dihydrospirorenon som anti-androgen - Google Patents

Anvendelse af dihydrospirorenon som anti-androgen

Info

Publication number
DK0398460T3
DK0398460T3 DK90250127.9T DK90250127T DK0398460T3 DK 0398460 T3 DK0398460 T3 DK 0398460T3 DK 90250127 T DK90250127 T DK 90250127T DK 0398460 T3 DK0398460 T3 DK 0398460T3
Authority
DK
Denmark
Prior art keywords
androgen
dihydrospirorenone
treatment
premenopause
oestrogen
Prior art date
Application number
DK90250127.9T
Other languages
Danish (da)
English (en)
Inventor
Sybille Dr Beier
Walter Dr Elger
Yukishige Dr Nishino
Rudolf Prof-Dr-Dr Wiechert
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6380839&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0398460(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Ag filed Critical Schering Ag
Application granted granted Critical
Publication of DK0398460T3 publication Critical patent/DK0398460T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Dental Preparations (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK90250127.9T 1989-05-16 1990-05-16 Anvendelse af dihydrospirorenon som anti-androgen DK0398460T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3916112A DE3916112A1 (de) 1989-05-16 1989-05-16 Dihydrospirorenon als antiandrogen

Publications (1)

Publication Number Publication Date
DK0398460T3 true DK0398460T3 (da) 1998-02-16

Family

ID=6380839

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90250127.9T DK0398460T3 (da) 1989-05-16 1990-05-16 Anvendelse af dihydrospirorenon som anti-androgen

Country Status (20)

Country Link
US (1) US5569652A (cs)
EP (1) EP0398460B1 (cs)
JP (1) JP2848919B2 (cs)
CN (1) CN1033948C (cs)
AT (1) ATE154881T1 (cs)
AU (1) AU642876B2 (cs)
BR (1) BR1101055A (cs)
CA (1) CA2016780C (cs)
DD (1) DD294417A5 (cs)
DE (3) DE3916112A1 (cs)
DK (1) DK0398460T3 (cs)
ES (1) ES2106728T3 (cs)
GR (1) GR3024861T3 (cs)
HU (1) HU213408B (cs)
IE (1) IE81143B1 (cs)
IL (1) IL94416A (cs)
LU (1) LU91065I2 (cs)
NL (1) NL300221I2 (cs)
PT (1) PT94038B (cs)
ZA (1) ZA903754B (cs)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4321957C2 (de) * 1993-07-01 1995-09-28 Marika Dr Med Ehrlich Verwendung eines hormonalen Mittels zur Therapie der Akne
DE4344462C2 (de) 1993-12-22 1996-02-01 Schering Ag Zusammensetzung für die Empfängnisverhütung
DE19651000A1 (de) * 1996-12-01 1998-06-04 Schering Ag Oxyiminopregnancarbolactone
EP2305267A3 (en) 1999-08-31 2011-08-17 Bayer Schering Pharma Aktiengesellschaft Pharmaceutical combination of ethinylestradiol and drospirenone for use as a contraceptive
US6787531B1 (en) * 1999-08-31 2004-09-07 Schering Ag Pharmaceutical composition for use as a contraceptive
SI1598069T1 (sl) * 1999-08-31 2009-10-31 Bayer Schering Pharma Ag Farmacevtska kombinacija etinilestradiola in drospirenona za uporabo kot kontracepitev
US20020132801A1 (en) * 2001-01-11 2002-09-19 Schering Aktiengesellschaft Drospirenone for hormone replacement therapy
AU2002222387A1 (en) * 2000-12-20 2002-07-01 Schering Aktiengesellschaft Cyclodextrin-drospirenone inclusion complexes
EP1216713A1 (en) 2000-12-20 2002-06-26 Schering Aktiengesellschaft Compositions of estrogen-cyclodextrin complexes
EP1216712A1 (en) * 2000-12-20 2002-06-26 Schering Aktiengesellschaft Cyclodextrin-drospirenone inclusion complexes
KR20040107481A (ko) * 2002-03-18 2004-12-20 파마시아 코포레이션 알도스테론 수용체 길항물질 및 담즙산 격리제의 혼합물
CN1642557A (zh) * 2002-03-18 2005-07-20 法玛西雅公司 醛固酮受体拮抗剂与烟酸或烟酸衍生物的组合
WO2004070048A1 (en) * 2003-02-07 2004-08-19 Pharmacia & Upjohn Company Llc A microbial process to prepare 5-androsten-3beta, 7alpha, 15alpha-triol-17-one and related analogues
NZ549792A (en) * 2004-03-10 2009-12-24 Bayer Schering Pharma Ag Compositions comprising drospirenone molecularly dispersed
MY142989A (en) * 2004-03-10 2011-02-14 Bayer Schering Pharma Ag Stabilised supersaturated solids of lipophilic drugs
US20050220825A1 (en) * 2004-03-10 2005-10-06 Adrian Funke Molecular dispersions of drospirenone
DE102004026670A1 (de) 2004-05-28 2005-12-15 Grünenthal GmbH Hormonales Kontrazeptivum enthaltend eine Kombination aus Ethinylestradiol und Chlormadinonacetat
DE102004026679A1 (de) 2004-05-28 2005-12-15 Grünenthal GmbH Hormonales Kontrazeptivum enthaltend eine Kombination aus Ethinylestradiol und Chlormadinonacetat
DE102004026669A1 (de) * 2004-05-28 2005-12-15 Grünenthal GmbH Verwendung einer Kombination aus Ethinylestradiol und Chlormadinonacetat zur Herstellung eines Arzneimittels
DE102004026671A1 (de) 2004-05-28 2005-12-15 Grünenthal GmbH Darreichungsform zur hormonalen Kontrazeption
ITMI20042338A1 (it) * 2004-12-06 2005-03-06 Ind Chimica Srl Processo per la preparazione di drospirenone
US8475838B2 (en) * 2005-06-03 2013-07-02 Sandoz Ag Rapidly-dissolving pharmaceutical composition for inhibiting ovulation
US7319154B2 (en) 2005-07-21 2008-01-15 Bayer Schering Pharma Ag Process for the production of 3-oxo-pregn-4-ene-21, 17-carbolactones by the metal free oxidation of 17-(3-hydroxypropyl)-3, 17-dihydroxyandrostanes
DK1746101T4 (da) 2005-07-21 2014-08-11 Bayer Pharma AG Fremgangsmåde til fremstilling af 3-oxo-pregn-4-en-21,17-carbolactoner ved metalfri oxidation af 17-(3-hydroxypropyl)-3,17-dihydroxyandrostaner
US20070275941A1 (en) * 2006-05-17 2007-11-29 Vladimir Hanes Salt sensitivity and prevention of hypertension with drospirenone
CA2725578A1 (en) * 2008-04-24 2009-10-29 Evestra, Inc. Oral contraceptive dosage forms comprising a progestogen dispersed in an enteric polymer and further comprising an estrogen
RS62297B1 (sr) 2011-11-23 2021-09-30 Therapeuticsmd Inc Prirodne kombinovane hormonske supstitucione formulacije i terapije
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
EP3145489A1 (en) 2014-05-22 2017-03-29 TherapeuticsMD, Inc. Natural combination hormone replacement formulations and therapies
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
KR20180126582A (ko) 2016-04-01 2018-11-27 쎄러퓨틱스엠디, 인코퍼레이티드 스테로이드 호르몬 약제학적 조성물
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2652761C2 (de) * 1976-11-16 1985-11-21 Schering AG, 1000 Berlin und 4709 Bergkamen 15,16-Methylen-Spirolactone, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
DE3022337A1 (de) * 1980-06-11 1982-01-07 Schering Ag Berlin Und Bergkamen, 1000 Berlin Praeparate zur kontrazeption und zur behandlung gynaekologischer stoerungen
US4347245A (en) * 1981-05-26 1982-08-31 German Shapiro Spironolactone-containing composition and use thereof
JPS59139400A (ja) * 1983-01-31 1984-08-10 Shionogi & Co Ltd 抗アルドステロン活性ステロイド誘導体
DE3402329A1 (de) * 1984-01-20 1985-08-01 Schering AG, 1000 Berlin und 4709 Bergkamen 6,6-ethylen-15,16-methylen-3-oxo-17(alpha)-pregn-4-en-21,17-carbolactone, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate
US4855289A (en) * 1984-06-04 1989-08-08 Wester Per O Combination of two active substances
US4729999A (en) * 1984-10-12 1988-03-08 Bcm Technologies Antiestrogen therapy for symptoms of estrogen deficiency
DE3615376A1 (de) * 1986-05-07 1987-11-12 Schering Ag 2,2;6,6-diethylen-3-oxo-17(alpha)-pregn-4-en-21,17-carbolactone, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate
IE61236B1 (en) * 1986-07-15 1994-10-19 American Home Prod Combination dosage form for pre-menopausal women

Also Published As

Publication number Publication date
IL94416A0 (en) 1991-03-10
CA2016780C (en) 2000-07-11
EP0398460A3 (de) 1991-09-25
DE122004000006I1 (de) 2006-06-08
NL300221I1 (nl) 2006-04-03
EP0398460A2 (de) 1990-11-22
PT94038B (pt) 1997-06-30
NL300221I2 (nl) 2006-11-01
HUT54500A (en) 1991-03-28
JPH0395121A (ja) 1991-04-19
DE3916112A1 (de) 1990-11-22
US5569652A (en) 1996-10-29
DE3916112C2 (cs) 1992-04-30
IE81143B1 (en) 2000-04-19
CN1047299A (zh) 1990-11-28
CA2016780A1 (en) 1990-11-16
AU5509490A (en) 1990-11-22
DD294417A5 (de) 1991-10-02
JP2848919B2 (ja) 1999-01-20
EP0398460B1 (de) 1997-07-02
CN1033948C (zh) 1997-02-05
ATE154881T1 (de) 1997-07-15
AU642876B2 (en) 1993-11-04
DE59010730D1 (de) 1997-08-07
BR1101055A (pt) 2000-08-08
LU91065I2 (fr) 2004-03-30
ZA903754B (en) 1991-02-27
PT94038A (pt) 1991-01-08
IE901738L (en) 1990-11-16
GR3024861T3 (en) 1998-01-30
ES2106728T3 (es) 1997-11-16
IL94416A (en) 1997-07-13
HU903045D0 (en) 1990-09-28
HU213408B (en) 1997-06-30

Similar Documents

Publication Publication Date Title
DK0398460T3 (da) Anvendelse af dihydrospirorenon som anti-androgen
FR2727005B1 (fr) Dispositif de stabilisation anterieure du rachis cervical
FR2624720B1 (fr) Implant pour dispositif d'osteosynthese, notamment du rachis
DK0476044T3 (da) Anvendelse af IGF1 eller IGF2 til fremstilling af et lægemiddeltil behandling af amyotrof, lateral sklerose
NO943521L (no) Anvendelse av et pyrrolidinacetamidderivat for fremstilling av et terapeutikum
IT1238825B (it) Dispositivo per la correzione chirurgica dell'ametropia.
DK0667768T3 (da) Anvendelse af toremifen til behandling af SLE
DE69125855D1 (de) Therapeutisch wirksame, örtliche anwendung von st1435
ES545155A0 (es) Procedimiento para la obtencion de (pirrol-1-il)-fenil-dihi-dropiridazinona
IT8947740A0 (it) Impiego di progestina per il trattamento delle osteoporosi
JPS5583758A (en) Novel 3*44diazaabicyclo*4*1*0*heptenee*2**onee *5**its manufacture and medicine containing it
ZA83856B (en) Thiazaspirane derivatives,processes for their preparation,and medicaments
NO970185L (no) Anvendelse av (S)-adenosyl-L-metionin (SAMe) og dets fysiologisk kompatible salter for behandling av reperfusjonsskade utlöst av temporær-fokal-ischemi
IT7821559A0 (it) Impianto endoosseo individuale perfezionato per odontostomatologia (chirurgia della bocca) eprocedimento per la sua rapida e perfetta applicazione al paziente.
ES2108870T3 (es) Aparato de rehabilitacion de las funciones labiolinguales basado en la busqueda de una satisfaccion.
FR2651998B1 (fr) Table de support de brancard notamment destinee a l'equipement d'ambulances.
ES2039255T3 (es) Utilizacion de n-((1-etil-2-pirrolidinil)metil)-2-metoxi-5-sulfamoil-benzamida en el tratamiento de la esterilidad.
IT1228977B (it) Apparecchio fisioterapico per la cura della sterilita' femminile accertata e per la dilatazione indolore del canale cervicale.
ATE134135T1 (de) Ein imidazobenzodiazepin zur behandlung von schlafstörungen
ES2043142T3 (es) Procedimiento para la obtencion de (+)-1,4-dihidro-5-isopropoxi-2-metil-4-(2-trifluormetilfenil)-1,6-naftiridin-3-carboxilato de (2-(n-metil-n-fenilmetilamino)etilo) fumarato.
RU95107865A (ru) Шина для лечения переломов челюсти
ITMI910370V0 (it) Dispositivo per il trattamento odontoiatrico nel caso di posizioni difettose in particolare dopo l'avvenuta regolazione della dentatura con anelli per denti per la regolazione fine
RU96100080A (ru) Лечение состояний, связанных с нарушением уровня паратгормона
IT1243947B (it) 2-azido-ornitina, sua preparazione e suo impiego in terapia
IT8519276A0 (it) Procedimento per la fabbricazione di supporti plantari attrezzati, per il trattamento ortesico delle plantalgie, e supporti plantari attrezzati, cosi' ottenuti.