DE69941498D1 - Hämostatische vernetzte Dextranperlen verwendbar zur schnellen Blutgerinnung und Hämostase - Google Patents

Hämostatische vernetzte Dextranperlen verwendbar zur schnellen Blutgerinnung und Hämostase

Info

Publication number
DE69941498D1
DE69941498D1 DE69941498T DE69941498T DE69941498D1 DE 69941498 D1 DE69941498 D1 DE 69941498D1 DE 69941498 T DE69941498 T DE 69941498T DE 69941498 T DE69941498 T DE 69941498T DE 69941498 D1 DE69941498 D1 DE 69941498D1
Authority
DE
Germany
Prior art keywords
cross
hemostatic
hemostasis
rapid blood
blood clotting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69941498T
Other languages
English (en)
Inventor
Kent C Cochrum
Robert A Gunther
Susan A Jemtrud
Franklin M Beninsig
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
INTERNAT Manufacturing GROUP Inc
THEIS JEROLD H
Original Assignee
INTERNAT Manufacturing GROUP Inc
THEIS JEROLD H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by INTERNAT Manufacturing GROUP Inc, THEIS JEROLD H filed Critical INTERNAT Manufacturing GROUP Inc
Application granted granted Critical
Publication of DE69941498D1 publication Critical patent/DE69941498D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/02Adhesive plasters or dressings
    • A61F13/0203Adhesive plasters or dressings having a fluid handling member
    • A61F13/01034
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/225Mixtures of macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/28Polysaccharides or their derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0023Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0052Mixtures of macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061Use of materials characterised by their function or physical properties
    • A61L26/0076Sprayable compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/15Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
    • A61F13/84Accessories, not otherwise provided for, for absorbent pads
    • A61F13/8405Additives, e.g. for odour, disinfectant or pH control
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F2013/00089Wound bandages
    • A61F2013/00119Wound bandages elastic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F2013/00089Wound bandages
    • A61F2013/00217Wound bandages not adhering to the wound
    • A61F2013/00229Wound bandages not adhering to the wound with alginate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F2013/00361Plasters
    • A61F2013/00365Plasters use
    • A61F2013/00463Plasters use haemostatic
    • A61F2013/00472Plasters use haemostatic with chemical means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F2013/00361Plasters
    • A61F2013/00902Plasters containing means
    • A61F2013/0091Plasters containing means with disinfecting or anaesthetics means, e.g. anti-mycrobic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F2013/00361Plasters
    • A61F2013/00902Plasters containing means
    • A61F2013/00927Plasters containing means with biological activity, e.g. enzymes for debriding wounds or others, collagen or growth factors
    • A61F2013/00931Plasters containing means with biological activity, e.g. enzymes for debriding wounds or others, collagen or growth factors chitin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/04Materials for stopping bleeding
DE69941498T 1998-11-12 1999-11-12 Hämostatische vernetzte Dextranperlen verwendbar zur schnellen Blutgerinnung und Hämostase Expired - Lifetime DE69941498D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10818598P 1998-11-12 1998-11-12
US29084699A 1999-04-13 1999-04-13

Publications (1)

Publication Number Publication Date
DE69941498D1 true DE69941498D1 (de) 2009-11-12

Family

ID=26805610

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69941498T Expired - Lifetime DE69941498D1 (de) 1998-11-12 1999-11-12 Hämostatische vernetzte Dextranperlen verwendbar zur schnellen Blutgerinnung und Hämostase

Country Status (9)

Country Link
US (2) US20050226916A1 (de)
EP (2) EP1156765A4 (de)
JP (1) JP2003517997A (de)
CN (1) CN1335757A (de)
AT (1) ATE444084T1 (de)
AU (1) AU1617800A (de)
CA (1) CA2350628A1 (de)
DE (1) DE69941498D1 (de)
WO (1) WO2000027327A1 (de)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0015682D0 (en) * 2000-06-28 2000-08-16 Bristol Myers Squibb Co Sprayable wound care composition
DE10204819A1 (de) * 2002-01-31 2003-08-14 Aesculap Ag & Co Kg Blutstillungsmittel und seine Bereitstellung für die Medizin
US6992233B2 (en) 2002-05-31 2006-01-31 Medafor, Inc. Material delivery system
WO2011066577A1 (en) * 2009-11-30 2011-06-03 Jeffrey Alan Klein Tumescent antibiotic solution
US11213481B2 (en) 2004-06-25 2022-01-04 Hk Pharma Tumescent drug delivery
US20060155235A1 (en) * 2004-12-17 2006-07-13 Sawyer Evelyn S Hemostatic compression bandage
US20070154509A1 (en) * 2005-12-30 2007-07-05 Wilcher Steve A Adsorbent-Containing Hemostatic Devices
US20070154510A1 (en) * 2005-12-30 2007-07-05 Wilcher Steve A Adsorbent-Containing Hemostatic Devices
DE102006006904A1 (de) * 2006-02-09 2007-08-23 Universität Rostock Neue Mittel zur Blutstillung und Klebstoffe für medizinische Anwendungen
US20080063697A1 (en) * 2006-09-08 2008-03-13 Bedard Robert L Use of Unactivated Calcium Exchanged Zeolites in Hemostatic Devices and Products
US20080145455A1 (en) * 2006-12-13 2008-06-19 Bedard Robert L Combination of Inorganic Hemostatic Agents with Other Hemostatic Agents
CN101254145B (zh) * 2007-02-28 2011-03-23 周长忠 多层次浅层创伤专用的亲水性敷料
US20090047366A1 (en) * 2007-08-15 2009-02-19 Bedard Robert L Inorganic Coagulation Accelerators for Individuals taking Platelet Blockers or Anticoagulants
US8883194B2 (en) * 2007-11-09 2014-11-11 Honeywell International, Inc. Adsorbent-containing hemostatic devices
US8629314B2 (en) 2007-12-18 2014-01-14 Ethicon, Inc. Surgical barriers having adhesion inhibiting properties
US8299316B2 (en) * 2007-12-18 2012-10-30 Ethicon, Inc. Hemostatic device
CN104888264B (zh) 2008-01-14 2018-01-09 北京环球利康科技有限公司 生物相容性止血、防粘连、促愈合、外科封闭的变性淀粉材料
WO2009109194A2 (en) 2008-02-29 2009-09-11 Ferrosan A/S Device for promotion of hemostasis and/or wound healing
MX338212B (es) 2008-04-11 2016-04-07 Univ Virginia Commonwealth Fibras de dextran electrohiladas y dispositivos formados de las mismas.
US10046081B2 (en) * 2008-04-11 2018-08-14 The Henry M Jackson Foundation For The Advancement Of Military Medicine, Inc. Electrospun dextran fibers and devices formed therefrom
US8795718B2 (en) * 2008-05-22 2014-08-05 Honeywell International, Inc. Functional nano-layered hemostatic material/device
US8574902B2 (en) 2009-03-05 2013-11-05 Macrocure Ltd. Activated leukocyte composition and uses for wound healing
RU2548741C2 (ru) * 2009-03-05 2015-04-20 Макрокьюэ, Лтд. Активированная лейкоцитарная композиция
US8828050B2 (en) 2009-05-04 2014-09-09 Oregon Biomedical Engineering Institute Hemorrhage control devices and methods
CA2814784C (en) * 2009-11-19 2022-07-26 Corporation De L'ecole Polytechnique De Montreal Soluble physiological chitosan formulations combined with platelet-rich plasma (prp) for tissue repair
EP2521612B1 (de) 2010-01-08 2017-05-17 University Of Tasmania Verwendung von porösen polymermonolithen
US9084728B2 (en) * 2010-06-01 2015-07-21 Baxter International Inc. Process for making dry and stable hemostatic compositions
EP2613765A2 (de) 2010-09-09 2013-07-17 Macrocure, Ltd. Mit aktivierten leukozyten konditionierter überstand und verwendung zur wundheilung
US9623223B2 (en) 2011-02-16 2017-04-18 Revmedx, Inc. Wound dressings comprising a plurality of liquid-expandable articles
WO2012112797A2 (en) * 2011-02-16 2012-08-23 Barofsky Andrew Wound stasis dressing for large surface wounds
GB201104175D0 (en) * 2011-03-11 2011-04-27 Medtrade Products Ltd Haemostatic material
AU2012283749B2 (en) 2011-07-12 2017-03-16 University Of Tasmania Use of porous polymer materials for storage of biological samples
US20130096479A1 (en) 2011-10-18 2013-04-18 St. Teresa Medical, Inc. Method of forming hemostatic products
CA2854294C (en) * 2011-10-18 2018-11-20 St. Teresa Medical, Inc. Method of forming dextran and thrombin sheets
DE102012002209A1 (de) * 2012-02-07 2013-08-08 Carl Freudenberg Kg Biodegradierbares Vlies für medizinische Zwecke
CN102579193A (zh) * 2012-02-28 2012-07-18 南通丝乡丝绸有限公司 丝绸芦荟创可贴
JP6241624B2 (ja) 2012-03-06 2017-12-06 フェロサン メディカル デバイシーズ エイ/エス 止血ペーストを収容する加圧容器
US10285681B2 (en) * 2012-05-08 2019-05-14 Protego Medical Pty Limited Apparatus for covering an exposed end of a severed sternum
JP6394916B2 (ja) 2012-06-12 2018-09-26 フェロサン メディカル デバイシーズ エイ/エス 乾燥止血組成物
AU2014283170B2 (en) 2013-06-21 2017-11-02 Ferrosan Medical Devices A/S Vacuum expanded dry composition and syringe for retaining same
US10772767B2 (en) 2013-06-28 2020-09-15 3M Innovative Properties Company Fibrin-coated wound dressing
CN103394078A (zh) * 2013-07-31 2013-11-20 中国人民解放军第四军医大学 一种自主加压多靶点协同止血的外伤急救用可降解止血制剂
CN103495174B (zh) * 2013-09-13 2015-10-07 中国人民解放军第四军医大学 用于治疗浅表性皮肤损伤的多效外用制剂及其用途
WO2015069897A1 (en) 2013-11-07 2015-05-14 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Red blood cell membrane-derived microparticles and their use for the treatment of lung disease
US9555157B2 (en) 2013-11-12 2017-01-31 St. Teresa Medical, Inc. Method of inducing hemostasis in a wound
CA2928963C (en) 2013-12-11 2020-10-27 Ferrosan Medical Devices A/S Dry composition comprising an extrusion enhancer
AU2015209243B2 (en) * 2014-01-24 2019-01-17 Avent, Inc. Traumatic wound dressing system with conformal cover
CN104257411A (zh) * 2014-09-19 2015-01-07 陈旭东 一种用于介入穿刺针道止血粒子及其匹配的植入枪
JP6726852B2 (ja) 2014-10-13 2020-07-22 フェッローサン メディカル ディバイス エー/エス 止血および創傷治癒に使用するための乾燥組成物
JP6747650B2 (ja) 2014-12-24 2020-08-26 フェロサン メディカル デバイシーズ エイ/エス 第1の物質と第2の物質を保持し混合するためのシリンジ
EA201791857A1 (ru) * 2015-02-16 2018-02-28 Петро Андрийович Манорык Гемостатическая композиция и гемостатическое средство (варианты)
CA2986981A1 (en) 2015-07-03 2017-01-12 Ferrosan Medical Devices A/S Syringe for mixing two components and for retaining a vacuum in a storage condition
CN105220357A (zh) * 2015-08-20 2016-01-06 徐波 一种水刺无纺布及制备方法
CN105054978B (zh) * 2015-08-26 2017-09-19 中国人民解放军南京军区福州总医院 弹链式连发填充止血式穿刺针及卡扣
CN108430526B (zh) 2015-11-08 2021-08-10 奥姆里克斯生物药品有限公司 纤维素基短纤维和长纤维的止血混合物
WO2017083050A1 (en) 2015-11-12 2017-05-18 St. Teresa Medical, Inc. A method of sealing a durotomy
US10939901B2 (en) * 2016-05-04 2021-03-09 Medtronic, Inc. Customizable anchorage devices and methods of use
US20210353501A1 (en) * 2017-03-31 2021-11-18 Medcura, Inc. Hydrophobically-modified polymer foams and methods of use
CN107335090B (zh) * 2017-07-11 2020-09-01 李徐奇 一种具有创面修复作用的生物相容性止血材料及其制备方法
US9919080B1 (en) * 2017-10-27 2018-03-20 Tyrx, Inc. Kits for local delivery of water soluble agents and methods of use
US10953128B2 (en) 2017-11-02 2021-03-23 St. Teresa Medical, Inc. Fibrin sealant products
EP3717028A1 (de) * 2017-11-28 2020-10-07 Baxter International Inc Absorbens zur wundbehandlung
CN108114309B (zh) * 2018-01-02 2020-08-14 大连理工大学 一种醛基葡聚糖/蒙脱土复合快速止血材料及其制备方法
JP7395113B2 (ja) 2018-05-09 2023-12-11 フェロサン メディカル デバイシーズ エイ/エス 止血組成物を調製する方法
CN110732037B (zh) 2018-07-20 2023-05-26 广州倍绣生物技术有限公司 止血糊剂及其制备方法
US11654057B2 (en) 2020-04-09 2023-05-23 Bio 54, Llc Devices for bleeding reduction and methods of making and using the same
CN111973798B (zh) * 2020-08-17 2021-11-30 广州润虹医药科技股份有限公司 一种快速止血可吸收微球及其制备方法
US11642324B1 (en) 2022-03-01 2023-05-09 Bio 54, Llc Topical tranexamic acid compositions and methods of use thereof

Family Cites Families (109)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US983073A (en) * 1908-05-28 1911-01-31 Arcade Mallet Kinematographic apparatus.
US974054A (en) * 1910-01-20 1910-10-25 Frank Guy Acetylene-lamp.
US2387642A (en) * 1942-03-25 1945-10-23 Calhoun Vernon Hemostat and method of forming same
US2914444A (en) * 1950-12-12 1959-11-24 David F Smith Cellulosic hemostatic composition
GB942305A (en) * 1958-12-23 1963-11-20 Parachem Corp Improvements in or relating to antiseptic film and method and apparatus for producing the same
US3042667A (en) * 1959-03-10 1962-07-03 Pharmacia Ab Process for producing dextran derivatives and products resulting therefrom
US3364200A (en) * 1960-03-28 1968-01-16 Johnson & Johnson Oxidized cellulose product and method for preparing the same
NL262878A (de) * 1960-03-28
US3206361A (en) * 1962-06-19 1965-09-14 Johnson & Johnson Stabilized methylaminoacetocatechol hemostatic wound dressing
US3507851A (en) * 1966-03-24 1970-04-21 Victor Ghetie Synthesis derivatives of agarose having application in electrophoresis on gel and in chromatography
US3722599A (en) * 1967-12-01 1973-03-27 Minnesota Mining & Mfg Fluorocyanoacrylates
US3527841A (en) * 1968-04-10 1970-09-08 Eastman Kodak Co Alpha-cyanoacrylate adhesive compositions
US3671280A (en) * 1970-12-04 1972-06-20 David F Smith Plaster of paris bandages to make casts of improved strength,water-resistance and physiological properties
US3940362A (en) * 1972-05-25 1976-02-24 Johnson & Johnson Cross-linked cyanoacrylate adhesive compositions
DE2247163A1 (de) * 1972-09-26 1974-03-28 Merck Patent Gmbh Traegermatrix zur fixierung biologisch wirksamer stoffe und verfahren zu ihrer herstellung
US3810473A (en) * 1972-12-04 1974-05-14 Avicon Inc Liquid-laid, non-woven, fibrous collagen derived surgical web having hemostatic and wound sealing properties
SE452109B (sv) * 1973-01-29 1987-11-16 Pharmacia Ab Rengoringsmedel for vetskande utvertes sarytor
US3920625A (en) * 1973-06-19 1975-11-18 Kabi Ab Isolation of coagulation factors from biological material using cross linked sulfated, sulfonated carbohydrates
FR2234311B1 (de) * 1973-06-21 1976-04-30 Air Liquide
JPS5394047A (en) * 1977-01-25 1978-08-17 Asahimatsu Koridofu Kk Production of soybean process food material
US4390519A (en) * 1978-05-19 1983-06-28 Sawyer Philip Nicholas Bandage with hemostatic agent and methods for preparing and employing the same
AT359652B (de) 1979-02-15 1980-11-25 Immuno Ag Verfahren zur herstellung eines gewebekleb- stoffes
AT359653B (de) 1979-02-15 1980-11-25 Immuno Ag Verfahren zur herstellung eines gewebekleb- stoffes
US4271144A (en) * 1979-06-06 1981-06-02 Holles Laboratories, Inc. Dextran composition for controlling corneal hydration
DE2950469C2 (de) * 1979-12-14 1983-12-01 I.M.A. Industria Macchine Automatiche S.p.A., Ozzano Emilia, Bologna Vorrichtung zum automatischen Schneiden von rechteckigen Platten mit abgerundeten Ecken
US4286592A (en) * 1980-02-04 1981-09-01 Alza Corporation Therapeutic system for administering drugs to the skin
JPS5758615A (en) * 1980-09-26 1982-04-08 Nippon Soda Co Ltd Film agnent and its preparation
US4793336A (en) * 1981-03-25 1988-12-27 Wang Paul Y Wound coverings and processes for their preparation
EP0068047B1 (de) * 1981-06-25 1986-07-23 Serapharm GmbH & Co. KG Angereichertes Plasmaderivat zur Unterstützung von Wundverschluss und Wundheilung
US4405324A (en) * 1981-08-24 1983-09-20 Morca, Inc. Absorbent cellulosic structures
DE3270438D1 (en) * 1981-09-30 1986-05-15 Leipzig Arzneimittel Absorbent wound dressing and processes for its production
SE430218B (sv) * 1981-12-30 1983-10-31 Blombaeck E G B Filter och sett att framstella ett sadant
DE3203775A1 (de) * 1982-02-04 1983-08-11 Behringwerke Ag, 3550 Marburg Fibrinogenzubereitung, verfahen zu ihrer herstellungund ihre verwendung
US4518721A (en) * 1982-03-26 1985-05-21 Richardson-Vicks Inc. Hydrophilic denture adhesive
GB2118482B (en) * 1982-04-17 1985-11-27 Tetsuya Nishino Pulp fiber structure
US4572932A (en) * 1982-04-23 1986-02-25 Rotork Controls Limited Actuating mechanism
US4543410A (en) * 1982-06-21 1985-09-24 Morca, Inc. Absorbent cellulosic base structures
CA1208558A (en) * 1982-10-07 1986-07-29 Kazuo Kigasawa Soft buccal
SE437270B (sv) * 1983-07-19 1985-02-18 Pharmacia Ab Separationsmaterial av tverbunden agaros och dess framstellning separationsmaterial av tverbunden agaros och dess framstellning
US4738849A (en) * 1984-06-28 1988-04-19 Interface Biomedical Laboratories Corp. Composite medical articles for application to wounds and method for producing same
JPS61122222A (ja) * 1984-11-19 1986-06-10 Koken:Kk コラ−ゲン又はゼラチンとプロタミンとよりなる止血剤
NO166836C (no) * 1985-03-14 1991-09-11 Univ California Fremgangsmaate for behandling av et organtransplantat.
US4616644A (en) * 1985-06-14 1986-10-14 Johnson & Johnson Products, Inc. Hemostatic adhesive bandage
JPH0744940B2 (ja) * 1986-12-24 1995-05-17 ライオン株式会社 口腔貼付用基材
US5225047A (en) * 1987-01-20 1993-07-06 Weyerhaeuser Company Crosslinked cellulose products and method for their preparation
DE3714074A1 (de) * 1987-04-28 1988-11-10 Hoechst Ag Grundlage fuer schleimhaut- und prothesenhaft-pasten, verfahren zu ihrer herstellung sowie pasten auf basis dieser grundlage
US4848329A (en) * 1987-09-01 1989-07-18 Herbert Dardik Mucoid absorbing dressing
JPH06104116B2 (ja) * 1988-11-29 1994-12-21 三菱化成株式会社 創傷被覆材
JP2656338B2 (ja) * 1989-01-31 1997-09-24 日東電工株式会社 口腔粘膜貼付製剤
US5015476A (en) * 1989-08-11 1991-05-14 Paravax, Inc. Immunization implant and method
US5298258A (en) * 1989-12-28 1994-03-29 Nitto Denko Corporation Acrylic oily gel bioadhesive material and acrylic oily gel preparation
US5185001A (en) * 1990-01-18 1993-02-09 The Research Foundation Of State University Of New York Method of preparing autologous plasma fibrin and application apparatus therefor
US5134915A (en) * 1990-03-19 1992-08-04 Mita Industrial Co., Ltd. Rolled-paper feed unit for an image forming apparatus
US5081041A (en) * 1990-04-03 1992-01-14 Minnesota Mining And Manufacturing Company Ionic component sensor and method for making and using same
US5098417A (en) * 1990-04-12 1992-03-24 Ricoh Kyosan, Inc. Cellulosic wound dressing with an active agent ionically absorbed thereon
US5241009A (en) * 1990-05-07 1993-08-31 Kimberly-Clark Corporation Polymeric composition containing carboxy nueutralized with lithium or potassium
NO171069C (no) * 1990-05-29 1993-01-20 Protan Biopolymer As Kovalent tverrbundne, sterkt svellende alkalimetall- og ammonium-alginatgeler, samt fremgangsmaate for fremstilling derav
US5196190A (en) * 1990-10-03 1993-03-23 Zenith Technology Corporation, Limited Synthetic skin substitutes
US6054122A (en) * 1990-11-27 2000-04-25 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US5279955A (en) * 1991-03-01 1994-01-18 Pegg Randall K Heterofunctional crosslinking agent for immobilizing reagents on plastic substrates
FR2679573B1 (fr) * 1991-07-25 1993-09-24 Perfojet Sa Procede pour la fabrication d'une nappe non tissee lavable a base de coton, et nappe ainsi obtenue.
US5192802A (en) * 1991-09-25 1993-03-09 Mcneil-Ppc, Inc. Bioadhesive pharmaceutical carrier
AU4402793A (en) * 1992-05-29 1993-12-30 Regents Of The University Of California, The Coated transplant and method for making same
WO1994013266A1 (en) * 1992-05-29 1994-06-23 The Regents Of The University Of California Novel electrostatic process for manufacturing coated transplants and products
US5521079A (en) * 1994-01-24 1996-05-28 The Regents Of The University Of California Microcapsule generating system containing an air knife and method of encapsulating
US5429821A (en) * 1992-05-29 1995-07-04 The Regents Of The University Of California Non-fibrogenic high mannuronate alginate coated transplants, processes for their manufacture, and methods for their use
US5643594A (en) * 1992-05-29 1997-07-01 The Regents Of The University Of California Spin encapsulation apparatus and method of use
US5470576A (en) * 1992-06-08 1995-11-28 The Kendall Company Process for preparing the alginate-containing wound dressing
CN1091315A (zh) * 1992-10-08 1994-08-31 E·R·斯奎布父子公司 血纤维蛋白封闭剂组合物及其使用方法
GB9225581D0 (en) * 1992-12-08 1993-01-27 Courtaulds Plc Wound dressings
US5330974A (en) * 1993-03-01 1994-07-19 Fibratek, Inc. Therapeutic fibrinogen compositions
GB2275686B (en) * 1993-03-03 1997-04-30 Johnson & Johnson Medical Swellable wound dressing materials
US5328687A (en) 1993-03-31 1994-07-12 Tri-Point Medical L.P. Biocompatible monomer and polymer compositions
US5624669A (en) 1993-03-31 1997-04-29 Tri-Point Medical Corporation Method of hemostatic sealing of blood vessels and internal organs
EP0726749B1 (de) * 1993-11-03 2004-08-11 Clarion Pharmaceuticals, Inc. Hämostatisches pflaster
US5876742A (en) * 1994-01-24 1999-03-02 The Regents Of The University Of California Biological tissue transplant coated with stabilized multilayer alginate coating suitable for transplantation and method of preparation thereof
US5502092A (en) * 1994-02-18 1996-03-26 Minnesota Mining And Manufacturing Company Biocompatible porous matrix of bioabsorbable material
US5406671A (en) * 1994-02-25 1995-04-18 Green; Daniel K. Trowel
US5514377A (en) * 1994-03-08 1996-05-07 The Regents Of The University Of California In situ dissolution of alginate coatings of biological tissue transplants
DE69530553T2 (de) * 1994-05-13 2004-03-25 KURARAY CO., LTD, Kurashiki Medizinisches polymergel
US5502042A (en) * 1994-07-22 1996-03-26 United States Surgical Corporation Methods and compositions for treating wounds
WO1996009115A1 (fr) * 1994-09-21 1996-03-28 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Adsorbant pour interleukines, procede d'elimination de celles-ci par adsorption et dispositif d'adsorption
US5585007A (en) * 1994-12-07 1996-12-17 Plasmaseal Corporation Plasma concentrate and tissue sealant methods and apparatuses for making concentrated plasma and/or tissue sealant
US5510102A (en) 1995-01-23 1996-04-23 The Regents Of The University Of California Plasma and polymer containing surgical hemostatic adhesives
US5614204A (en) * 1995-01-23 1997-03-25 The Regents Of The University Of California Angiographic vascular occlusion agents and a method for hemostatic occlusion
US5733545A (en) * 1995-03-03 1998-03-31 Quantic Biomedical Partners Platelet glue wound sealant
US5900245A (en) * 1996-03-22 1999-05-04 Focal, Inc. Compliant tissue sealants
US5795581A (en) * 1995-03-31 1998-08-18 Sandia Corporation Controlled release of molecular components of dendrimer/bioactive complexes
US5643192A (en) * 1995-04-06 1997-07-01 Hamilton Civic Hospitals Research Development, Inc. Autologous fibrin glue and methods for its preparation and use
US5795570A (en) * 1995-04-07 1998-08-18 Emory University Method of containing core material in microcapsules
EP0821573A4 (de) * 1995-04-19 2000-08-09 St Jude Medical Substrat-matrize für eine prothese bestehend aus biologischem lebenden gewebe sowie verfahren zur herstellung dieser matrize
DE19521324C1 (de) * 1995-06-12 1996-10-31 Immuno Ag Gewebeklebstoff und Verwendung desselben als Hämostyptikum
US5800372A (en) * 1996-01-09 1998-09-01 Aerojet-General Corporation Field dressing for control of exsanguination
US5642749A (en) * 1996-02-21 1997-07-01 Perryman; Joyce F. Crutch clutch holder
US5773833A (en) * 1996-03-22 1998-06-30 Rae Systems, Inc. Photo-ionization detector for volatile gas measurement
DE69719754D1 (de) * 1996-05-23 2003-04-17 Xoma Technology Ltd Therapeutische verwendungen von bpi-protein produkten bei menschen mit durch trauma verursachter blutung
US5811151A (en) * 1996-05-31 1998-09-22 Medtronic, Inc. Method of modifying the surface of a medical device
US6083522A (en) * 1997-01-09 2000-07-04 Neucoll, Inc. Devices for tissue repair and methods for preparation and use thereof
US5866165A (en) * 1997-01-15 1999-02-02 Orquest, Inc. Collagen-polysaccharide matrix for bone and cartilage repair
US6200595B1 (en) * 1998-04-24 2001-03-13 Kuraray Co., Ltd. Medical adhesive
US6056970A (en) * 1998-05-07 2000-05-02 Genzyme Corporation Compositions comprising hemostatic compounds and bioabsorbable polymers
US6261679B1 (en) * 1998-05-22 2001-07-17 Kimberly-Clark Worldwide, Inc. Fibrous absorbent material and methods of making the same
US6060461A (en) * 1999-02-08 2000-05-09 Drake; James Franklin Topically applied clotting material
US6391048B1 (en) * 2000-01-05 2002-05-21 Integrated Vascular Systems, Inc. Integrated vascular device with puncture site closure component and sealant and methods of use
US6627785B1 (en) * 2000-02-29 2003-09-30 Virginia Commwealth University Wound dressings with protease-lowering activity
US20030089463A1 (en) * 2001-10-01 2003-05-15 Briscoe Thomas R. Pressure vent hurricane shutter
AU2002361902A1 (en) * 2001-12-31 2003-07-24 Ares Medical, Inc. Hemostatic compositions and methods for controlling bleeding
US6992233B2 (en) * 2002-05-31 2006-01-31 Medafor, Inc. Material delivery system
US20040101546A1 (en) * 2002-11-26 2004-05-27 Gorman Anne Jessica Hemostatic wound dressing containing aldehyde-modified polysaccharide and hemostatic agents

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WO2000027327A1 (en) 2000-05-18
CN1335757A (zh) 2002-02-13
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EP1156765A4 (de) 2002-08-07
AU1617800A (en) 2000-05-29
EP1156765A1 (de) 2001-11-28
EP1731175B1 (de) 2009-09-30
EP1731175A1 (de) 2006-12-13
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US20070255238A1 (en) 2007-11-01
CA2350628A1 (en) 2000-05-18

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