DE69920824D1 - Inhalationsapparat - Google Patents

Inhalationsapparat

Info

Publication number
DE69920824D1
DE69920824D1 DE69920824T DE69920824T DE69920824D1 DE 69920824 D1 DE69920824 D1 DE 69920824D1 DE 69920824 T DE69920824 T DE 69920824T DE 69920824 T DE69920824 T DE 69920824T DE 69920824 D1 DE69920824 D1 DE 69920824D1
Authority
DE
Germany
Prior art keywords
inhalation apparatus
inhalation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69920824T
Other languages
English (en)
Other versions
DE69920824T2 (de
Inventor
Hisamoto Ohki
Yoshiyuki Yazawa
Shigemi Nakamura
Kazunori Ishizeki
Akira Yanagawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dott Co Ltd
Hitachi Ltd
Original Assignee
Dott Co Ltd
Unisia Jecs Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dott Co Ltd, Unisia Jecs Corp filed Critical Dott Co Ltd
Publication of DE69920824D1 publication Critical patent/DE69920824D1/de
Application granted granted Critical
Publication of DE69920824T2 publication Critical patent/DE69920824T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/002—Details of inhalators; Constructional features thereof with air flow regulating means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
DE69920824T 1998-02-06 1999-01-28 Inhalationsapparat Expired - Lifetime DE69920824T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP4141098 1998-02-06
JP04141098A JP3530004B2 (ja) 1998-02-06 1998-02-06 吸入式投薬器
PCT/JP1999/000356 WO1999039761A1 (en) 1998-02-06 1999-01-28 Inhalant medicator

Publications (2)

Publication Number Publication Date
DE69920824D1 true DE69920824D1 (de) 2004-11-11
DE69920824T2 DE69920824T2 (de) 2005-12-22

Family

ID=12607598

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69920824T Expired - Lifetime DE69920824T2 (de) 1998-02-06 1999-01-28 Inhalationsapparat

Country Status (8)

Country Link
US (1) US6273086B1 (de)
EP (1) EP0973571B1 (de)
JP (1) JP3530004B2 (de)
CN (1) CN1255869A (de)
DE (1) DE69920824T2 (de)
PT (1) PT973571E (de)
WO (1) WO1999039761A1 (de)
ZA (1) ZA99877B (de)

Families Citing this family (83)

* Cited by examiner, † Cited by third party
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JP3739955B2 (ja) * 1999-01-11 2006-01-25 株式会社日立製作所 吸入式投薬器
JP2000217917A (ja) 1999-01-27 2000-08-08 Unisia Jecs Corp 吸入式投薬器
GB2353222B (en) 1999-06-23 2001-09-19 Cambridge Consultants Inhalers
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US7305986B1 (en) 1999-07-23 2007-12-11 Mannkind Corporation Unit dose capsules for use in a dry powder inhaler
US7464706B2 (en) 1999-07-23 2008-12-16 Mannkind Corporation Unit dose cartridge and dry powder inhaler
EP1177805A1 (de) * 2000-07-31 2002-02-06 Maryland Financial Inc. Pulverinhalator
SE517227C2 (sv) * 2000-09-25 2002-05-14 Microdrug Ag Inhalator för torrt pulver med folieskärare
US6595210B2 (en) * 2000-11-27 2003-07-22 Unisia Jecs Corporation Inhalator for administering powder composition
GB2375308A (en) * 2001-05-10 2002-11-13 Cambridge Consultants Inhalers
WO2002089879A1 (en) 2001-05-10 2002-11-14 Vectura Delivery Devices Limited Inhalers
ITMI20020078A1 (it) * 2002-01-16 2003-07-16 Fabrizio Niccolai Dispositivo utilizzabile nel tratamento di affezzioni delle vie respiratorie
EP1894591B1 (de) 2002-03-20 2013-06-26 MannKind Corporation Kartusche für eine Inhalationsvorrichtung
PL375162A1 (en) * 2002-07-08 2005-11-28 Pliva-Istrazivacki Institut D.O.O. Novel compounds, compositions as carriers for steroid/non-steroid anti-inflammatory, antineoplastic and antiviral active molecules
WO2004005310A2 (en) * 2002-07-08 2004-01-15 Pliva-Istrazivacki Institut D.O.O. New compounds, compositions and methods for treatment of inflammatory diseases and conditions
MXPA05006321A (es) 2002-12-13 2005-08-26 Otsuka Pharma Co Ltd Dispositivo de inhalacion para administracion transpulmonar.
US7669596B2 (en) * 2002-12-31 2010-03-02 Novartis Pharma Ag Aerosolization apparatus with rotating capsule
US20050056280A1 (en) * 2002-12-31 2005-03-17 Nektar Therapeutics Receptacle for an aerosolizable pharmaceutical formulation
WO2004073729A1 (ja) 2003-02-21 2004-09-02 Translational Research Ltd. 薬物の経鼻投与用組成物
CA2519287A1 (en) * 2003-03-27 2004-10-14 Bioactis Limited Powder medicine applicator for nasal cavity
DK1615689T3 (da) * 2003-04-09 2016-03-14 Novartis Ag Apparatur til dannelse af en aerosol og omfattende en opretningsføring til punktering af en kapsel
HRP20030324A2 (en) 2003-04-24 2005-02-28 Pliva-Istra�iva�ki institut d.o.o. Compounds of antiinflammatory effect
EP1785145A4 (de) * 2004-08-10 2008-08-13 Translational Res Ltd Transnasale zusammensetzung mit sofortiger wirkung und hoher resorbierbarkeit
PL1786784T3 (pl) 2004-08-20 2011-04-29 Mannkind Corp Kataliza syntezy diketopiperazyn
CN101027057B (zh) 2004-08-23 2017-04-12 曼金德公司 用于药物输送的二酮哌嗪盐、二酮吗啉盐或二酮二氧杂环己烷盐
MX2007004106A (es) 2004-10-06 2007-06-14 Boehringer Ingelheim Int Dispositivo dispensador, dispositivo de almacenamiento y metodo para dispensar polvo.
EP1805202B1 (de) 2004-10-27 2009-12-30 GlaxoSmithKline istrazivacki centar Zagreb d.o.o. Konjugate mit entzündungshemmender aktivität
JP2006130143A (ja) * 2004-11-08 2006-05-25 Hitachi Ltd 吸入式投薬器及び薬剤カートリッジ
GB0427028D0 (en) * 2004-12-09 2005-01-12 Cambridge Consultants Dry powder inhalers
US7943634B2 (en) * 2004-12-17 2011-05-17 Glenmark Pharmaceuticals S.A. Substituted benzo[4,5]furo[3,2-c]pyridine derivatives as PDE 4 inhibitors
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GB0427856D0 (en) * 2004-12-20 2005-01-19 Glaxo Group Ltd Maniflod for use in medicament dispenser
GB0427853D0 (en) * 2004-12-20 2005-01-19 Glaxo Group Ltd Manifold for use in medicament dispenser
GB0427858D0 (en) * 2004-12-20 2005-01-19 Glaxo Group Ltd Manifold for use in medicament dispenser
CN100431634C (zh) * 2005-04-04 2008-11-12 陈庆堂 干粉气溶胶化吸入器
US7833979B2 (en) * 2005-04-22 2010-11-16 Amgen Inc. Toxin peptide therapeutic agents
EP1901793A1 (de) * 2005-07-13 2008-03-26 Cipla Ltd. Inhalator
US8008453B2 (en) 2005-08-12 2011-08-30 Amgen Inc. Modified Fc molecules
EP1928423B1 (de) 2005-09-14 2015-12-09 Mannkind Corporation Verfahren zur arzneimittelformulierung basierend auf der affinitätssteigerung von aktiven wirkstoffen für kristalline mikropartikel-flächen
DE102005046645B3 (de) * 2005-09-29 2006-07-20 Braunform Gmbh Pulverinhalator
AR058290A1 (es) * 2005-12-12 2008-01-30 Glaxo Group Ltd Dispensador de medicamento
AR058289A1 (es) * 2005-12-12 2008-01-30 Glaxo Group Ltd Colector para ser usado en dispensador de medicamento
DE102006007495A1 (de) 2006-02-17 2007-08-23 Siegfried Generics International Ag Dispergiereinheit
AU2013205495B2 (en) * 2006-02-17 2015-11-26 Sanofi Sa Dispersing unit
ES2647080T3 (es) 2006-02-22 2017-12-19 Mannkind Corporation Un método para mejorar las propiedades farmacéuticas de micropartículas que comprenden dicetopiperazina y un agente activo
DE102006014434A1 (de) * 2006-03-27 2007-10-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Packmittel für Mehrdosispulverinhalatoren mit optimierten Entleerungseigenschaften
MX2008016153A (es) * 2006-06-16 2009-01-20 Cipla Ltd Inhalador mejorado de polvo seco.
WO2008088422A2 (en) * 2006-10-25 2008-07-24 Amgen Inc. Toxin peptide therapeutic agents
JP4850050B2 (ja) * 2006-12-15 2012-01-11 日立オートモティブシステムズ株式会社 粉末薬剤投与器
WO2008078730A1 (ja) * 2006-12-26 2008-07-03 Translational Research, Ltd. 経鼻投与用製剤
EP2738257A1 (de) 2007-05-22 2014-06-04 Amgen Inc. Zusammensetzungen und Verfahren zur Herstellung bioaktiver Fusionsproteine
EP2020249A1 (de) * 2007-08-01 2009-02-04 Boehringer Ingelheim Pharma GmbH & Co. KG Inhalator
EP2254629B1 (de) * 2008-03-27 2015-11-04 MannKind Corporation System für trockenpulverinhalation
EP2567723B1 (de) 2008-06-13 2021-01-20 MannKind Corporation Trockenpulverinhalator und System zur Wirkstofffreisetzung
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
ES2421385T3 (es) 2008-06-20 2013-09-02 Mannkind Corp Aparato interactivo y procedimiento para establecer el perfil, en tiempo real, de esfuerzos de inhalación
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
EP2676695A3 (de) 2009-03-11 2017-03-01 MannKind Corporation Vorrichtung, System und Verfahren zur Messung des Widerstandes eines Inhalators
WO2010131486A1 (en) * 2009-05-15 2010-11-18 Shin Nippon Biomedical Laboratories, Ltd. Intranasal pharmaceutical compositions with improved pharmacokinetics
KR20210027546A (ko) 2009-06-12 2021-03-10 맨카인드 코포레이션 한정된 비표면적을 갖는 디케토피페라진 마이크로입자
WO2011013003A2 (en) 2009-07-31 2011-02-03 Shin Nippon Biomedical Laboratories, Ltd. Intranasal granisetron and nasal applicator
CA2778698A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
MX2012005514A (es) * 2009-11-13 2012-06-14 Merck Sharp & Dohme Productos de medicamento, inhaladores de polvo seco y dispositivo colisionador de multiflujo.
CA2781313C (en) * 2009-12-23 2019-09-17 Map Pharmaceuticals, Inc. Enhanced eductor design
KR20130117755A (ko) 2010-06-21 2013-10-28 맨카인드 코포레이션 건조 분말 약물 운반 시스템 및 방법
JP5960726B2 (ja) 2011-01-31 2016-08-02 株式会社新日本科学 鼻腔内送達デバイス
CA2830065A1 (en) 2011-03-16 2012-09-20 Amgen Inc. Potent and selective inhibitors of nav1.3 and nav1.7
EP2694402B1 (de) 2011-04-01 2017-03-22 MannKind Corporation Blisterverpackung für pharmakartuschen
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
US9233159B2 (en) 2011-10-24 2016-01-12 Mannkind Corporation Methods and compositions for treating pain
AU2013289957B2 (en) 2012-07-12 2017-02-23 Mannkind Corporation Dry powder drug delivery systems and methods
EP2911690A1 (de) 2012-10-26 2015-09-02 MannKind Corporation Inhalierbare influenza-impfstoffzusammensetzungen und verfahren
UY35397A (es) 2013-03-12 2014-10-31 Amgen Inc INHIBIDORES POTENTES Y SELECTIVOS DE NaV1.7
MX369136B (es) 2013-03-15 2019-10-30 Mannkind Corp Composiciones de dicetopiperazina microcristalina y metodos.
KR102465025B1 (ko) 2013-07-18 2022-11-09 맨카인드 코포레이션 열-안정성 건조 분말 약제학적 조성물 및 방법
US11446127B2 (en) 2013-08-05 2022-09-20 Mannkind Corporation Insufflation apparatus and methods
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
ES2760943T3 (es) * 2016-05-23 2020-05-18 Presspart Mfg Ltd Inhalador de polvo seco
US11318190B2 (en) 2017-05-05 2022-05-03 United States Government As Represented By The Department Of Veterans Affairs Methods and compositions for treating liver disease
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EP3911390B1 (de) * 2019-01-14 2022-10-26 Philip Morris Products, S.A. Trockenpulverinhalator, trockenpulverkartusche, und kit

Family Cites Families (8)

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Publication number Priority date Publication date Assignee Title
GB1459426A (en) 1973-02-26 1976-12-22 Allen & Hanburys Ltd Inhalation devices
FR2224175B1 (de) * 1973-04-04 1978-04-14 Isf Spa
US5476093A (en) * 1992-02-14 1995-12-19 Huhtamaki Oy Device for more effective pulverization of a powdered inhalation medicament
DE4208880A1 (de) * 1992-03-19 1993-09-23 Boehringer Ingelheim Kg Separator fuer pulverinhalatoren
JP3372105B2 (ja) 1994-05-26 2003-01-27 株式会社日立ユニシアオートモティブ 吸入式投薬器
JP3320261B2 (ja) * 1995-06-01 2002-09-03 株式会社ユニシアジェックス 吸入式投薬器
SE9502032D0 (sv) 1995-06-02 1995-06-02 Burkhard Lachmann Arrangement for determining an opening pressure
DE19522416C2 (de) * 1995-06-21 2003-11-20 Sofotec Gmbh & Co Kg Vorrichtung zum Dispergieren von Pulver in einem Luftstrom zur Verwendung mit Pulver-Inhalatoren

Also Published As

Publication number Publication date
PT973571E (pt) 2005-02-28
CN1255869A (zh) 2000-06-07
WO1999039761A1 (en) 1999-08-12
JP3530004B2 (ja) 2004-05-24
DE69920824T2 (de) 2005-12-22
US6273086B1 (en) 2001-08-14
JPH11221280A (ja) 1999-08-17
ZA99877B (en) 1999-08-05
EP0973571A1 (de) 2000-01-26
EP0973571B1 (de) 2004-10-06

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: HITACHI, LTD., TOKIO/TOKYO, JP

Owner name: DOTT LTD. CO., YOKOHAMA, KANAGAWA, JP

8332 No legal effect for de
8370 Indication related to discontinuation of the patent is to be deleted
8364 No opposition during term of opposition