DE69913958D1 - Nichtkristalline feste dispergierende Zusammensetzung mit Cefuroximaxetil - Google Patents
Nichtkristalline feste dispergierende Zusammensetzung mit CefuroximaxetilInfo
- Publication number
- DE69913958D1 DE69913958D1 DE69913958T DE69913958T DE69913958D1 DE 69913958 D1 DE69913958 D1 DE 69913958D1 DE 69913958 T DE69913958 T DE 69913958T DE 69913958 T DE69913958 T DE 69913958T DE 69913958 D1 DE69913958 D1 DE 69913958D1
- Authority
- DE
- Germany
- Prior art keywords
- cefuroxime axetil
- crystalline solid
- organic solvent
- solid dispersing
- dispersing composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
- A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1019990031989A KR100342943B1 (ko) | 1999-08-04 | 1999-08-04 | 비결정질 세푸록심 악세틸 고형분산체, 이의 제조 방법 및 이를 포함하는 경구투여용 조성물 |
KR9931989 | 1999-08-04 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69913958D1 true DE69913958D1 (de) | 2004-02-05 |
DE69913958T2 DE69913958T2 (de) | 2004-06-09 |
Family
ID=19606197
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69913958T Expired - Lifetime DE69913958T2 (de) | 1999-08-04 | 1999-09-10 | Nichtkristalline feste dispergierende Zusammensetzung mit Cefuroximaxetil |
Country Status (19)
Country | Link |
---|---|
US (1) | US6107290A (de) |
EP (1) | EP1080721B1 (de) |
JP (1) | JP3479244B2 (de) |
KR (1) | KR100342943B1 (de) |
CN (1) | CN1189161C (de) |
AT (1) | ATE257010T1 (de) |
AU (1) | AU769451B2 (de) |
CA (1) | CA2378267A1 (de) |
CZ (1) | CZ2002372A3 (de) |
DE (1) | DE69913958T2 (de) |
ES (1) | ES2212438T3 (de) |
HU (1) | HUP0202192A3 (de) |
MX (1) | MXPA02001116A (de) |
NZ (1) | NZ516760A (de) |
RU (1) | RU2215521C1 (de) |
SI (1) | SI20747A (de) |
TR (1) | TR200200287T2 (de) |
WO (1) | WO2001010410A1 (de) |
YU (1) | YU7502A (de) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT413647B (de) | 1998-11-26 | 2006-04-15 | Sandoz Ag | Verwendung eines copolymerisats aus 1-vinyl-2-pyrrolidon und vinylacetat zur herstellung von cefuroximaxetil-hältigen tabletten |
IN191496B (de) | 1999-07-30 | 2003-12-06 | Ranbaxy Lab Ltd | |
KR100362230B1 (ko) * | 2000-04-21 | 2002-11-23 | 주식회사 대웅제약 | 저융점 무정형 세푸록심 악세틸의 제조방법 |
AU2001230490A1 (en) * | 2000-12-01 | 2002-06-11 | Arun Shriniwas Gosavi | Pharmaceutical formulation |
US6779246B2 (en) * | 2001-04-23 | 2004-08-24 | Appleton Papers Inc. | Method and system for forming RF reflective pathways |
US6892441B2 (en) * | 2001-04-23 | 2005-05-17 | Appleton Papers Inc. | Method for forming electrically conductive pathways |
ATE486586T1 (de) * | 2001-06-22 | 2010-11-15 | Pfizer Prod Inc | Pharmazeutische zusammensetzungen, enthaltend adsorbate eines arzneimittels in amorpher form |
JP2005523262A (ja) * | 2002-02-01 | 2005-08-04 | ファイザー・プロダクツ・インク | 薬物及び親油性ミクロ相形成物質の非晶質分散物の医薬組成物 |
TW200403075A (en) * | 2002-05-29 | 2004-03-01 | Akzo Nobel Nv | Progestagenic dosage units |
KR100523082B1 (ko) * | 2002-09-11 | 2005-10-20 | (주)다산메디켐 | 쓴 맛이 은폐된 세푸록심악세틸 제제의 제약조성물 및 그의 제조방법 |
JP2006056781A (ja) * | 2002-11-15 | 2006-03-02 | Bioserentack Co Ltd | 界面活性剤を含む固形化製剤 |
MXPA06001417A (es) | 2003-08-04 | 2006-05-15 | Pfizer Prod Inc | Composiciones farmaceuticas de adsorbatos de farmacos amorfos y materiales que forman microfases lipofilas. |
KR101178657B1 (ko) * | 2003-10-08 | 2012-08-30 | 메이지 세이카 파루마 가부시키가이샤 | 세프디토렌 피복실을 함유하는 비결정질 항균 조성물 |
JP2007517864A (ja) * | 2004-01-09 | 2007-07-05 | ハンミ ファーム. シーオー., エルティーディー. | セフロキシムアキセチル顆粒及びこの製造方法 |
KR100801589B1 (ko) | 2004-01-09 | 2008-02-05 | 한미약품 주식회사 | 세푸록심 악세틸 과립 및 이의 제조방법 |
CN100402035C (zh) * | 2005-07-07 | 2008-07-16 | 石药集团中奇制药技术(石家庄)有限公司 | 一种微囊化头孢呋辛酯的药物组合物 |
US20070128268A1 (en) * | 2005-12-07 | 2007-06-07 | Herwig Jennewein | Pharmaceutical compositions comprising an antibiotic |
JP5893461B2 (ja) | 2011-04-07 | 2016-03-23 | 日産自動車株式会社 | 位置検出装置および位置検出方法 |
ES2821528T3 (es) | 2012-11-14 | 2021-04-26 | Grace W R & Co | Composiciones que contienen un material biológicamente activo y un óxido inorgánico no ordenado |
TWI586379B (zh) * | 2015-06-29 | 2017-06-11 | 永信藥品工業股份有限公司 | 一種製作難溶藥物固體劑型的方法 |
CN116284050B (zh) * | 2022-12-19 | 2024-04-12 | 华北制药河北华民药业有限责任公司 | 一种高效率结晶型头孢呋辛酯转无定型粉体的方法及产品 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
YU44680B (en) * | 1982-07-30 | 1990-12-31 | Glaxo Lab Ltd | Process for obtaining very pure amorphous form of cephuroxim axetile |
GB8524001D0 (en) * | 1985-09-30 | 1985-11-06 | Glaxo Group Ltd | Pharmaceutical composition |
NL193682C (nl) * | 1987-05-14 | 2000-07-04 | Glaxo Group Ltd | Beklede cefuroximaxetilsamenstelling. |
IN186539B (de) * | 1997-09-29 | 2001-09-29 | Ranbaxy Lab Ltd | |
AT413647B (de) * | 1998-11-26 | 2006-04-15 | Sandoz Ag | Verwendung eines copolymerisats aus 1-vinyl-2-pyrrolidon und vinylacetat zur herstellung von cefuroximaxetil-hältigen tabletten |
-
1999
- 1999-08-04 KR KR1019990031989A patent/KR100342943B1/ko not_active IP Right Cessation
- 1999-09-10 ES ES99117885T patent/ES2212438T3/es not_active Expired - Lifetime
- 1999-09-10 AT AT99117885T patent/ATE257010T1/de not_active IP Right Cessation
- 1999-09-10 DE DE69913958T patent/DE69913958T2/de not_active Expired - Lifetime
- 1999-09-10 EP EP99117885A patent/EP1080721B1/de not_active Expired - Lifetime
- 1999-09-16 US US09/397,745 patent/US6107290A/en not_active Expired - Fee Related
- 1999-10-14 JP JP29217699A patent/JP3479244B2/ja not_active Expired - Fee Related
-
2000
- 2000-07-25 SI SI200020034A patent/SI20747A/sl not_active IP Right Cessation
- 2000-07-25 HU HU0202192A patent/HUP0202192A3/hu unknown
- 2000-07-25 CA CA002378267A patent/CA2378267A1/en not_active Abandoned
- 2000-07-25 CZ CZ2002372A patent/CZ2002372A3/cs unknown
- 2000-07-25 CN CNB008112134A patent/CN1189161C/zh not_active Expired - Fee Related
- 2000-07-25 RU RU2002105504/15A patent/RU2215521C1/ru not_active IP Right Cessation
- 2000-07-25 WO PCT/KR2000/000799 patent/WO2001010410A1/en not_active Application Discontinuation
- 2000-07-25 TR TR2002/00287T patent/TR200200287T2/xx unknown
- 2000-07-25 YU YU7502A patent/YU7502A/sh unknown
- 2000-07-25 MX MXPA02001116A patent/MXPA02001116A/es active IP Right Grant
- 2000-07-25 NZ NZ516760A patent/NZ516760A/en unknown
- 2000-07-25 AU AU58551/00A patent/AU769451B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
ES2212438T3 (es) | 2004-07-16 |
MXPA02001116A (es) | 2002-08-20 |
NZ516760A (en) | 2004-01-30 |
CN1367683A (zh) | 2002-09-04 |
YU7502A (sh) | 2004-09-03 |
EP1080721A2 (de) | 2001-03-07 |
JP3479244B2 (ja) | 2003-12-15 |
US6107290A (en) | 2000-08-22 |
RU2215521C1 (ru) | 2003-11-10 |
KR20010016826A (ko) | 2001-03-05 |
EP1080721A3 (de) | 2001-05-02 |
EP1080721B1 (de) | 2004-01-02 |
SI20747A (sl) | 2002-06-30 |
KR100342943B1 (ko) | 2002-07-02 |
AU769451B2 (en) | 2004-01-29 |
CN1189161C (zh) | 2005-02-16 |
ATE257010T1 (de) | 2004-01-15 |
CA2378267A1 (en) | 2001-02-15 |
TR200200287T2 (tr) | 2002-07-22 |
JP2001048777A (ja) | 2001-02-20 |
WO2001010410A1 (en) | 2001-02-15 |
HUP0202192A2 (en) | 2002-10-28 |
CZ2002372A3 (cs) | 2002-06-12 |
HUP0202192A3 (en) | 2004-04-28 |
AU5855100A (en) | 2001-03-05 |
DE69913958T2 (de) | 2004-06-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |