DE69840495D1 - Darreichungsform, welche rasche dispersionseigenschaften entfaltet, anwendungsverfahren sowie verfahren zur herstellung derselben - Google Patents

Darreichungsform, welche rasche dispersionseigenschaften entfaltet, anwendungsverfahren sowie verfahren zur herstellung derselben

Info

Publication number
DE69840495D1
DE69840495D1 DE1998640495 DE69840495A DE69840495D1 DE 69840495 D1 DE69840495 D1 DE 69840495D1 DE 1998640495 DE1998640495 DE 1998640495 DE 69840495 A DE69840495 A DE 69840495A DE 69840495 D1 DE69840495 D1 DE 69840495D1
Authority
DE
Grant status
Grant
Patent type
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE1998640495
Other languages
English (en)
Inventor
Jaedeok Yoo
Sandeep Kumar
Donald C Monkhouse
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Massachusetts Institute of Technology
Original Assignee
Massachusetts Institute of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Grant date

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B33ADDITIVE MANUFACTURING TECHNOLOGY
    • B33YADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y80/00Products made by additive manufacturing
DE1998640495 1997-02-20 1998-02-20 Darreichungsform, welche rasche dispersionseigenschaften entfaltet, anwendungsverfahren sowie verfahren zur herstellung derselben Expired - Lifetime DE69840495D1 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US3888397 true 1997-02-20 1997-02-20
US3828497 true 1997-02-20 1997-02-20
PCT/US1998/003256 WO1998036738A1 (en) 1997-02-20 1998-02-20 Dosage form exhibiting rapid disperse properties, methods of use and process for the manufacture of same

Publications (1)

Publication Number Publication Date
DE69840495D1 true DE69840495D1 (de) 2009-03-12

Family

ID=26715043

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1998640495 Expired - Lifetime DE69840495D1 (de) 1997-02-20 1998-02-20 Darreichungsform, welche rasche dispersionseigenschaften entfaltet, anwendungsverfahren sowie verfahren zur herstellung derselben

Country Status (7)

Country Link
US (3) US6471992B1 (de)
EP (1) EP0973507B1 (de)
JP (3) JP4563516B2 (de)
CA (1) CA2281473C (de)
DE (1) DE69840495D1 (de)
ES (1) ES2318869T3 (de)
WO (1) WO1998036738A1 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4563516B2 (ja) 1997-02-20 2010-10-13 マサチューセッツ インスティテュート オブ テクノロジー 迅速分散性を示す投与剤形、その使用法並びにその製造方法
WO1999059544A9 (en) * 1998-05-18 2008-02-21 Takeda Chemical Industries Ltd Orally disintegrable tablets
US6284270B1 (en) * 1999-08-04 2001-09-04 Drugtech Corporation Means for creating a mass having structural integrity
EP1301177A2 (de) * 2000-07-10 2003-04-16 Massachusetts Institute Of Technology Verfahren und materialien zur steuerung der wanderung einer binderflüssigkeit in ein pulver
KR20090029314A (ko) * 2001-06-28 2009-03-20 유씨비 파쉼 소시에떼아노님 세티리진 및 슈도에페드린을 포함하는 정제
JP4426286B2 (ja) * 2001-07-10 2010-03-03 テバ ファーマシューティカル インダストリーズ リミティド 0次、0次−二相性、上昇型又は下降型薬物放出のための薬物送達システム
JP4845340B2 (ja) * 2001-10-29 2011-12-28 マサチューセッツ インスティテュート オブ テクノロジー 三次元プリント投薬形態のような物品の一軸圧縮のためのシステムおよび方法
WO2003041690A3 (en) * 2001-10-29 2003-08-28 Therics Inc Three-dimensional suspension printing of dosage forms
DE60323482D1 (de) 2002-05-06 2008-10-23 Massachusetts Inst Technology Diffusionskontrollierte arzneiform sowie herstellungsmethode mittels dreidimensionalem drucken
WO2004047793A1 (en) * 2002-11-26 2004-06-10 Alk-Abelló A/S Pharmaceutical allergen product
ES2378452T3 (es) 2004-09-21 2012-04-12 Hypnion, Inc. �?cido 3-[4-(dibenzo[b,f][1,4]oxazepin-11-il)-piperazin-1-il]-2,2¿dimetil-propanoico para usarlo en el tratamiento de trastornos del sueño
ES2500165T3 (es) 2006-06-29 2014-09-30 Kinex Pharmaceuticals, Llc Composiciones de biarilo y métodos para modular una cascada de quinasas
US7829000B2 (en) * 2005-02-25 2010-11-09 Hewlett-Packard Development Company, L.P. Core-shell solid freeform fabrication
US8187659B2 (en) 2006-05-02 2012-05-29 Jerry Robertson Real Estate Llc Solid medicament dosage form consumption aid
EP3195858A1 (de) * 2010-04-03 2017-07-26 Praful Doshi Medizinische vorrichtungen mit medikamenten sowie verfahren zu ihrer herstellung und verwendung
US8692001B2 (en) 2010-10-27 2014-04-08 Dynamix Pharmaceuticals Ltd. Sulfonamides for the modulation of PKM2
WO2012106058A3 (en) 2011-01-31 2012-11-08 New Market Pharmaceuticals Animal treatments
US20120302609A1 (en) 2011-05-25 2012-11-29 Dynamix Pharmaceuticals Ltd. Pyrazolines for the Modulation of PKM2
US8937065B2 (en) 2011-06-07 2015-01-20 Clevexel Pharma Compositions and methods for modulating a kinase
US9245061B2 (en) * 2012-04-25 2016-01-26 Shapeways, Inc. Weight-based identification of three dimensional printed parts
CA2872396A1 (en) 2012-05-02 2013-11-07 New Market Pharmaceuticals Pharmaceutical compositions for direct systemic introduction
ES2664332T3 (es) 2012-08-30 2018-04-19 Athenex, Inc. N-(3-fluorobencil)-2-(5-(4-morfolinofenil)piridin-2-il) acetamida como moduladores de la proteína tirosina quinasa
US9545376B2 (en) 2013-01-23 2017-01-17 Arx, Llc Production of unit dose constructs
CA2906172A1 (en) * 2013-03-15 2014-09-18 Aprecia Pharmaceuticals Company Rapidly dispersible dosage form of topiramate
CA2906029C (en) * 2013-03-15 2017-09-05 Aprecia Pharmaceuticals Company Rapid disperse dosage form containing levetiracetam
CA2906107A1 (en) 2013-03-15 2014-09-18 Aprecia Pharmaceuticals Company Rapidly dispersible dosage form of oxcarbazepine
US9339489B2 (en) 2013-03-15 2016-05-17 Aprecia Pharmaceuticals Company Rapid disperse dosage form containing levetiracetam
EP3033188A4 (de) 2013-08-16 2017-03-22 The Exone Company Dreidimensionale bedruckte metallgussformen und verfahren zur herstellung davon
WO2015100084A1 (en) 2013-12-23 2015-07-02 The Exone Company Method of three-dimensional printing using a multi-component build powder
EP3086921A4 (de) * 2013-12-23 2017-08-16 The Exone Company Verfahren und systeme zum dreidimensionalen drucken unter verwendung einer bindemittelflüssigkeit mit ausgestrahlten partikeln
WO2015100086A4 (en) 2013-12-23 2015-08-06 The Exone Company Methods and systems for three-dimensional printing utilizing multiple binder fluids
EP3137113A4 (de) * 2014-04-30 2017-03-22 Blaesi Aron H Schmelzverarbeitete polymere zelluläre darreichungsform
EP3148730A1 (de) 2014-05-29 2017-04-05 The Exone Company Verfahren zur herstellung von superlegierungsartikeln auf nickelbasis durch dreidimensionales drucken
WO2016011098A4 (en) 2014-07-17 2016-05-26 The Exone Company Methods and apparatuses for curing three-dimensional printed articles
KR20170137032A (ko) 2014-11-21 2017-12-12 바이오하벤 파마슈티컬 홀딩 컴퍼니 엘티디. 릴루졸의 설하 제제
WO2017158172A1 (en) * 2016-03-18 2017-09-21 Grünenthal GmbH Combination of drugs having different potency

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4642903A (en) 1985-03-26 1987-02-17 R. P. Scherer Corporation Freeze-dried foam dosage form
US4855326A (en) 1987-04-20 1989-08-08 Fuisz Pharmaceutical Ltd. Rapidly dissoluble medicinal dosage unit and method of manufacture
US4990535A (en) * 1989-05-03 1991-02-05 Schering Corporation Pharmaceutical composition comprising loratadine, ibuprofen and pseudoephedrine
US5206025A (en) 1989-05-24 1993-04-27 Rhone-Poulenc Sante Porous pharmaceutical form and its preparation
FR2647343B1 (fr) * 1989-05-24 1994-05-06 Rhone Poulenc Sante Nouvelle forme pharmaceutique poreuse et sa preparation
EP0418596A3 (en) * 1989-09-21 1991-10-23 American Cyanamid Company Controlled release pharmaceutical compositions from spherical granules in tabletted oral dosage unit form
US5204055A (en) 1989-12-08 1993-04-20 Massachusetts Institute Of Technology Three-dimensional printing techniques
US5578322A (en) 1990-11-30 1996-11-26 Yamanouchi Pharmaceutical Co., Ltd. Quick release coated preparation
DK0500225T3 (da) 1991-01-31 1996-02-05 Texas Instruments Inc System, fremgangsmåde og proces til computerstyret fremstilling af tredimensionale genstande udfra computerdata
CA2124686C (en) * 1991-12-20 1998-06-16 Julian B. Lo Porous shaped delivery devices and method of producing thereof
JP2521612B2 (ja) * 1992-05-20 1996-08-07 ウエイ・ミン・フアーマシユーテイカル・マニユフアクチヤリング・カンパニー・リミテツド 直接錠剤形成助剤
US5518730A (en) 1992-06-03 1996-05-21 Fuisz Technologies Ltd. Biodegradable controlled release flash flow melt-spun delivery system
US5380473A (en) 1992-10-23 1995-01-10 Fuisz Technologies Ltd. Process for making shearform matrix
DE4303846A1 (de) * 1993-02-10 1994-08-11 Merck Patent Gmbh Verfahren zur Herstellung einer S-Ibuprofen enthaltenden Tablette
US5631023A (en) 1993-07-09 1997-05-20 R.P. Scherer Corporation Method for making freeze dried drug dosage forms
US6176874B1 (en) 1993-10-18 2001-01-23 Masschusetts Institute Of Technology Vascularized tissue regeneration matrices formed by solid free form fabrication techniques
US5490962A (en) * 1993-10-18 1996-02-13 Massachusetts Institute Of Technology Preparation of medical devices by solid free-form fabrication methods
US5503785A (en) 1994-06-02 1996-04-02 Stratasys, Inc. Process of support removal for fused deposition modeling
US5633021A (en) 1994-10-19 1997-05-27 Bpm Technology, Inc. Apparatus for making a three-dimensional article
US5607697A (en) 1995-06-07 1997-03-04 Cima Labs, Incorporated Taste masking microparticles for oral dosage forms
US5560927A (en) * 1995-07-28 1996-10-01 Isp Investments Inc. Co-processing method for making a free-flowing compressible powder and tablet therefrom
US5653925A (en) * 1995-09-26 1997-08-05 Stratasys, Inc. Method for controlled porosity three-dimensional modeling
US6280771B1 (en) 1997-02-20 2001-08-28 Therics, Inc. Dosage forms exhibiting multi-phasic release kinetics and methods of manufacture thereof
JP4563516B2 (ja) * 1997-02-20 2010-10-13 マサチューセッツ インスティテュート オブ テクノロジー 迅速分散性を示す投与剤形、その使用法並びにその製造方法
DE19940944B4 (de) * 1999-08-31 2006-10-12 Grünenthal GmbH Retardierte, orale, pharmazeutische Darreichungsformen

Also Published As

Publication number Publication date Type
CA2281473A1 (en) 1998-08-27 application
US9463160B2 (en) 2016-10-11 grant
EP0973507A1 (de) 2000-01-26 application
WO1998036738A1 (en) 1998-08-27 application
JP2009215305A (ja) 2009-09-24 application
US20120207929A1 (en) 2012-08-16 application
JP2001512488A (ja) 2001-08-21 application
EP0973507B1 (de) 2009-01-21 grant
CA2281473C (en) 2007-01-16 grant
EP0973507A4 (de) 2006-08-23 application
ES2318869T3 (es) 2009-05-01 grant
JP2010120938A (ja) 2010-06-03 application
US9114072B2 (en) 2015-08-25 grant
JP4563516B2 (ja) 2010-10-13 grant
JP5091910B2 (ja) 2012-12-05 grant
US20030133975A1 (en) 2003-07-17 application
US6471992B1 (en) 2002-10-29 grant

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Legal Events

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