DE69630881D1 - Fernprogrammierbare matrizen mit speichern und verwendungen davon - Google Patents
Fernprogrammierbare matrizen mit speichern und verwendungen davonInfo
- Publication number
- DE69630881D1 DE69630881D1 DE69630881T DE69630881T DE69630881D1 DE 69630881 D1 DE69630881 D1 DE 69630881D1 DE 69630881 T DE69630881 T DE 69630881T DE 69630881 T DE69630881 T DE 69630881T DE 69630881 D1 DE69630881 D1 DE 69630881D1
- Authority
- DE
- Germany
- Prior art keywords
- molecules
- substrate
- support matrix
- storage
- particle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000002245 particle Substances 0.000 abstract 4
- 239000011159 matrix material Substances 0.000 abstract 3
- 239000000758 substrate Substances 0.000 abstract 3
- 230000000694 effects Effects 0.000 abstract 2
- 238000003556 assay Methods 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
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- C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
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- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B70/00—Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes
-
- G01N15/149—
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00732—Identification of carriers, materials or components in automatic analysers
- G01N2035/00742—Type of codes
- G01N2035/00782—Type of codes reprogrammmable code
-
- G—PHYSICS
- G11—INFORMATION STORAGE
- G11C—STATIC STORES
- G11C13/00—Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00
- G11C13/02—Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00 using elements whose operation depends upon chemical change
- G11C13/025—Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00 using elements whose operation depends upon chemical change using fullerenes, e.g. C60, or nanotubes, e.g. carbon or silicon nanotubes
Applications Claiming Priority (19)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US428662 | 1995-04-25 | ||
US08/428,662 US5741462A (en) | 1995-04-25 | 1995-04-25 | Remotely programmable matrices with memories |
US480147 | 1995-06-07 | ||
US08/480,147 US6352854B1 (en) | 1995-04-25 | 1995-06-07 | Remotely programmable matrices with memories |
US08/473,660 US6331273B1 (en) | 1995-04-25 | 1995-06-07 | Remotely programmable matrices with memories |
US08/484,486 US6416714B1 (en) | 1995-04-25 | 1995-06-07 | Remotely programmable matrices with memories |
US08/484,504 US5751629A (en) | 1995-04-25 | 1995-06-07 | Remotely programmable matrices with memories |
US484504 | 1995-06-07 | ||
US08/480,196 US5925562A (en) | 1995-04-25 | 1995-06-07 | Remotely programmable matrices with memories |
US480196 | 1995-06-07 | ||
US473660 | 1995-06-07 | ||
US484486 | 1995-06-07 | ||
US08/538,387 US5874214A (en) | 1995-04-25 | 1995-10-03 | Remotely programmable matrices with memories |
US538387 | 1995-10-03 | ||
US567746 | 1995-12-05 | ||
US08/567,746 US6025129A (en) | 1995-04-25 | 1995-12-05 | Remotely programmable matrices with memories and uses thereof |
US63981396A | 1996-04-02 | 1996-04-02 | |
US639813 | 1996-04-02 | ||
PCT/US1996/006145 WO1996036436A1 (en) | 1995-04-25 | 1996-04-25 | Remotely programmable matrices with memories and uses thereof |
Publications (2)
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DE69630881D1 true DE69630881D1 (de) | 2004-01-08 |
DE69630881T2 DE69630881T2 (de) | 2004-09-02 |
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Application Number | Title | Priority Date | Filing Date |
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DE69630881T Expired - Lifetime DE69630881T2 (de) | 1995-04-25 | 1996-04-25 | Fernprogrammierbare matrizen mit speichern und verwendungen davon |
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Country | Link |
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US (5) | US7935659B2 (de) |
EP (1) | EP0822861B1 (de) |
JP (1) | JPH11511238A (de) |
KR (1) | KR19990008052A (de) |
CN (1) | CN1181720A (de) |
AT (1) | ATE254965T1 (de) |
AU (1) | AU707444B2 (de) |
CA (1) | CA2216645A1 (de) |
DE (1) | DE69630881T2 (de) |
EA (1) | EA199700257A1 (de) |
WO (1) | WO1996036436A1 (de) |
Families Citing this family (156)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6100973A (en) * | 1994-03-18 | 2000-08-08 | Spectra Science Corporation | Methods and apparatus for performing microanalytical techniques using photolithographically fabricated substrates having narrow band optical emission capability |
US6100026A (en) * | 1995-04-25 | 2000-08-08 | Irori | Matrices with memories and uses thereof |
US5925562A (en) * | 1995-04-25 | 1999-07-20 | Irori | Remotely programmable matrices with memories |
US5961923A (en) * | 1995-04-25 | 1999-10-05 | Irori | Matrices with memories and uses thereof |
KR19990008052A (ko) * | 1995-04-25 | 1999-01-25 | 마이클 피 노바 | 기억 장치를 갖는 원격적으로 프로그램 가능한 매트릭스 및 이의 용도 |
US6284459B1 (en) | 1995-04-25 | 2001-09-04 | Discovery Partners International | Solid support matrices with memories and combinatorial libraries therefrom |
US5736332A (en) * | 1995-11-30 | 1998-04-07 | Mandecki; Wlodek | Method of determining the sequence of nucleic acids employing solid-phase particles carrying transponders |
US6001571A (en) | 1995-11-30 | 1999-12-14 | Mandecki; Wlodek | Multiplex assay for nucleic acids employing transponders |
JP2000502887A (ja) * | 1995-11-30 | 2000-03-14 | ウロデック マンデッキ | 生体分子の電子的固相アッセイ |
US6051377A (en) * | 1995-11-30 | 2000-04-18 | Pharmaseq, Inc. | Multiplex assay for nucleic acids employing transponders |
US5641634A (en) | 1995-11-30 | 1997-06-24 | Mandecki; Wlodek | Electronically-indexed solid-phase assay for biomolecules |
WO1997019958A1 (en) | 1995-11-30 | 1997-06-05 | Wlodek Mandecki | Screening of drugs from chemical combinatorial libraries employing transponders |
AU4976797A (en) * | 1996-10-07 | 1998-05-05 | Irori | Matrices with memories in automated drug discovery and units therefor |
US6136274A (en) * | 1996-10-07 | 2000-10-24 | Irori | Matrices with memories in automated drug discovery and units therefor |
US5981166A (en) * | 1997-04-23 | 1999-11-09 | Pharmaseq, Inc. | Screening of soluble chemical compounds for their pharmacological properties utilizing transponders |
US7160687B1 (en) * | 1997-05-29 | 2007-01-09 | Cellomics, Inc. | Miniaturized cell array methods and apparatus for cell-based screening |
US6096496A (en) | 1997-06-19 | 2000-08-01 | Frankel; Robert D. | Supports incorporating vertical cavity emitting lasers and tracking apparatus for use in combinatorial synthesis |
EP0950114A4 (de) * | 1997-07-22 | 2004-07-28 | Symyx Technologies Inc | Kodierung von organometallischen bibliotheken |
DE19736470C2 (de) * | 1997-08-21 | 2001-02-22 | Ulrich Schenck | Datenverarbeitungsfähiger Mikroskopie-Probenträger und Verfahren zur Analyse von mikroskopierbaren Proben |
AU2583899A (en) * | 1998-02-04 | 1999-08-23 | Invitrogen Corporation | Microarrays and uses therefor |
US6027695A (en) * | 1998-04-01 | 2000-02-22 | Dupont Pharmaceuticals Company | Apparatus for holding small volumes of liquids |
WO1999049974A1 (en) * | 1998-04-01 | 1999-10-07 | The Du Pont Merck Pharmaceutical Company | Plate apparatus for holding small volumes of liquids |
GB9808783D0 (en) * | 1998-04-25 | 1998-06-24 | Central Research Lab Ltd | Labelling of small articles |
GB9812783D0 (en) | 1998-06-12 | 1998-08-12 | Cenes Ltd | High throuoghput screen |
EP2045334A1 (de) | 1998-06-24 | 2009-04-08 | Illumina, Inc. | Dekodierung von Arraysensoren mit Mikrosphären |
US7384733B1 (en) | 1998-12-05 | 2008-06-10 | Xention Discovery Limited | Interface patch clamping |
EP1151302B1 (de) * | 1999-02-09 | 2010-03-31 | Illumina, Inc. | Screeningverfahren mit porösen mikrokügelchen und zusammensetzungen |
US6432719B1 (en) * | 1999-02-16 | 2002-08-13 | Pe Corporation (Ny) | Matrix storage and dispensing system |
US7101510B2 (en) | 1999-02-16 | 2006-09-05 | Applera Corporation | Matrix storage and dispensing system |
US6908737B2 (en) | 1999-04-15 | 2005-06-21 | Vitra Bioscience, Inc. | Systems and methods of conducting multiplexed experiments |
US7253435B2 (en) | 1999-04-15 | 2007-08-07 | Millipore Corporation | Particles with light-polarizing codes |
AU4245900A (en) * | 1999-04-15 | 2000-11-02 | Virtual Arrays, Inc. | Combinatorial chemical library supports having indicia at coding positions and methods of use |
IL145970A0 (en) * | 1999-04-16 | 2002-07-25 | Tibotec Nv | Encoding of microcarriers |
US6759235B2 (en) | 2000-04-06 | 2004-07-06 | Quantum Dot Corporation | Two-dimensional spectral imaging system |
DE10059890A1 (de) * | 2000-12-01 | 2002-06-20 | Hte Ag | Verfahren zur Herstellung einer Vielzahl von Bausteinen einer Materialbibliothek |
US7189800B2 (en) | 2001-03-27 | 2007-03-13 | Samuel Bogoch | Replikin peptides in rapid replication of glioma cells and in influenza epidemics |
NZ592340A (en) | 2001-03-27 | 2012-12-21 | Elenore S Bogoch | A method for making a virus vaccine compising Replikin peptides |
US7774144B2 (en) | 2001-10-26 | 2010-08-10 | Samuel Bogoch | System and method for identifying complex patterns of amino acids |
US7572642B2 (en) | 2001-04-18 | 2009-08-11 | Ambrigen, Llc | Assay based on particles, which specifically bind with targets in spatially distributed characteristic patterns |
CN100485032C (zh) * | 2001-05-11 | 2009-05-06 | 松下电器产业株式会社 | 生物分子基底,使用它的检验和诊断方法及装置 |
US6800491B2 (en) | 2001-06-08 | 2004-10-05 | Nalge Nunc International Corporation | Robotic reservoir without liquid hangup |
GB2387903A (en) * | 2002-04-24 | 2003-10-29 | Smartbead Technologies Ltd | Multiparameter analysis using tagged molecules |
JP4409426B2 (ja) * | 2002-05-28 | 2010-02-03 | オウトジエノミクス・インコーポレーテツド | マイクロアレイ検出器および方法 |
GB2391230A (en) * | 2002-07-26 | 2004-02-04 | Smartbead Technologies Ltd | Multiparameter assays using coded supports |
US7901630B2 (en) | 2002-08-20 | 2011-03-08 | Illumina, Inc. | Diffraction grating-based encoded microparticle assay stick |
US7923260B2 (en) | 2002-08-20 | 2011-04-12 | Illumina, Inc. | Method of reading encoded particles |
US7872804B2 (en) | 2002-08-20 | 2011-01-18 | Illumina, Inc. | Encoded particle having a grating with variations in the refractive index |
US7164533B2 (en) * | 2003-01-22 | 2007-01-16 | Cyvera Corporation | Hybrid random bead/chip based microarray |
US7092160B2 (en) | 2002-09-12 | 2006-08-15 | Illumina, Inc. | Method of manufacturing of diffraction grating-based optical identification element |
CA2498916A1 (en) * | 2002-09-12 | 2004-03-25 | Cyvera Corporation | Chemical synthesis using diffraction grating-based encoded optical elements |
WO2004065000A1 (en) | 2003-01-21 | 2004-08-05 | Illumina Inc. | Chemical reaction monitor |
US8494781B2 (en) | 2003-06-06 | 2013-07-23 | Samuel Bogoch | Systems and methods for identifying replikin scaffolds and uses of said replikin scaffolds |
NZ580449A (en) * | 2003-09-11 | 2011-06-30 | Theranos Inc | Ingestible medical device with biocompatible polymer coating, device with microarray to interact with disease marker |
US7187286B2 (en) | 2004-03-19 | 2007-03-06 | Applera Corporation | Methods and systems for using RFID in biological field |
SG151298A1 (en) | 2004-04-08 | 2009-04-30 | Biomatrica Inc | Integration of sample storage and sample management for life science |
KR101270934B1 (ko) * | 2004-04-28 | 2013-06-21 | 엘레노어 에스 보고치 | 아미노산의 복합 패턴을 확인하는 시스템 및 방법 |
US9254315B2 (en) | 2004-04-28 | 2016-02-09 | Samuel Bogoch | Systems and methods for identifying replikin scaffolds and uses of said replikin scaffolds |
WO2006055736A1 (en) | 2004-11-16 | 2006-05-26 | Illumina, Inc. | And methods and apparatus for reading coded microbeads |
EP1856525A4 (de) | 2005-03-10 | 2015-12-09 | Raustech Pty Ltd | Diskettensubstrate für kombinatorische chemie |
US7830575B2 (en) | 2006-04-10 | 2010-11-09 | Illumina, Inc. | Optical scanner with improved scan time |
EP2639579B1 (de) * | 2006-12-14 | 2016-11-16 | Life Technologies Corporation | Vorrichtung zur Messung von Analyten mithilfe großer FET-Arrays |
KR100842730B1 (ko) * | 2007-01-16 | 2008-07-01 | 삼성전자주식회사 | 멀티 비트 전기 기계적 메모리 소자 및 그의 제조방법 |
US7960139B2 (en) | 2007-03-23 | 2011-06-14 | Academia Sinica | Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells |
US8080372B2 (en) * | 2007-04-11 | 2011-12-20 | Canon Kabushiki Kaisha | Method for detecting nucleic acid in sample, method for designing probes, system for designing probes therefor |
AU2008266702A1 (en) | 2007-05-30 | 2008-12-24 | Elenore S. Bogoch | Synthetic replikin peptides against pathogenic infection of invertebrates in aquaculture |
WO2009064843A1 (en) * | 2007-11-13 | 2009-05-22 | Bayer Healthcare Llc | Method to measure amino acid concentrations |
WO2009064425A1 (en) * | 2007-11-13 | 2009-05-22 | Rational Affinity Devices, L.L.C. | Multistate affinity ligands for the separation and purification of antibodies, antibody fragments and conjugates of antibodies and antibody fragments |
JP5043810B2 (ja) * | 2007-12-26 | 2012-10-10 | パナソニック株式会社 | 生体試料測定装置およびこれを備えた生体試料測定システム |
ES2312290B1 (es) * | 2008-05-14 | 2009-09-22 | Grifols, S.A. | Dispositivo lector de microtubos para analisis de muestras de sangre. |
ES2442024T3 (es) | 2008-07-15 | 2014-02-07 | Academia Sinica | Matrices de glucano sobre portaobjetos de vidrio revestidos con aluminio de tipo PTFE y métodos relacionados |
US8405379B1 (en) | 2008-09-18 | 2013-03-26 | Luc Montagnier | System and method for the analysis of DNA sequences in biological fluids |
US9233148B2 (en) | 2009-01-09 | 2016-01-12 | Samuel Bogoch | Replikin-based compounds for prevention and treatment of influenza and methods of differentiating infectivity and lethality in influenza |
US8741591B2 (en) | 2009-10-09 | 2014-06-03 | The Research Foundation For The State University Of New York | pH-insensitive glucose indicator protein |
EP2494353B1 (de) | 2009-10-30 | 2017-09-27 | Illumina Inc. | Vorrichtung mit einer Mehrzahl von codierten Mikrogefäßen und einer Vielzahl von Fächern und ein Verfahren zum Lesen einer Mehrzahl von codierten Mikrogefäßen |
US10087236B2 (en) | 2009-12-02 | 2018-10-02 | Academia Sinica | Methods for modifying human antibodies by glycan engineering |
US11377485B2 (en) | 2009-12-02 | 2022-07-05 | Academia Sinica | Methods for modifying human antibodies by glycan engineering |
US8835358B2 (en) | 2009-12-15 | 2014-09-16 | Cellular Research, Inc. | Digital counting of individual molecules by stochastic attachment of diverse labels |
US9315857B2 (en) | 2009-12-15 | 2016-04-19 | Cellular Research, Inc. | Digital counting of individual molecules by stochastic attachment of diverse label-tags |
WO2011130332A1 (en) | 2010-04-12 | 2011-10-20 | Academia Sinica | Glycan arrays for high throughput screening of viruses |
US9845489B2 (en) | 2010-07-26 | 2017-12-19 | Biomatrica, Inc. | Compositions for stabilizing DNA, RNA and proteins in saliva and other biological samples during shipping and storage at ambient temperatures |
JP5933544B2 (ja) | 2010-07-26 | 2016-06-08 | バイオマトリカ, インコーポレーテッド | 外界温度で出荷および貯蔵中の血中dna、rnaおよびタンパク質ならびに他の生体試料を安定化させるための組成物 |
US8668886B2 (en) * | 2011-04-24 | 2014-03-11 | Therapeutic Proteins International, LLC | Separative bioreactor |
US9057712B1 (en) | 2011-10-27 | 2015-06-16 | Copilot Ventures Fund Iii Llc | Methods of delivery of encapsulated perfluorocarbon taggants |
CN104271767B (zh) | 2012-02-03 | 2017-08-25 | 加州理工学院 | 多路生化测定中信号的编码和解码 |
EP2820174B1 (de) | 2012-02-27 | 2019-12-25 | The University of North Carolina at Chapel Hill | Verfahren und verwendung für molekulare tags |
EP3321378B1 (de) | 2012-02-27 | 2021-11-10 | Becton, Dickinson and Company | Zusammensetzungen für molekularen zählung |
US10130714B2 (en) | 2012-04-14 | 2018-11-20 | Academia Sinica | Enhanced anti-influenza agents conjugated with anti-inflammatory activity |
US9914956B2 (en) | 2012-08-18 | 2018-03-13 | Academia Sinica | Cell-permeable probes for identification and imaging of sialidases |
WO2014100755A2 (en) | 2012-12-20 | 2014-06-26 | Biomatrica, Inc. | Formulations and methods for stabilizing pcr reagents |
KR101397599B1 (ko) * | 2012-12-28 | 2014-05-30 | 한국기계연구원 | 전자후방산란회절 맵핑 결과 상의 상인식 오류의 필터링 방법 |
JP5898119B2 (ja) * | 2013-03-28 | 2016-04-06 | シスメックス株式会社 | 分析装置 |
CN104156739B (zh) * | 2013-05-14 | 2019-09-10 | 上海亨臻实业有限公司 | 电子标签亲和配体库及用途 |
WO2014210397A1 (en) | 2013-06-26 | 2014-12-31 | Academia Sinica | Rm2 antigens and use thereof |
US9981030B2 (en) | 2013-06-27 | 2018-05-29 | Academia Sinica | Glycan conjugates and use thereof |
KR102536833B1 (ko) | 2013-08-28 | 2023-05-26 | 벡톤 디킨슨 앤드 컴퍼니 | 대량의 동시 단일 세포 분석 |
AU2014317889B2 (en) | 2013-09-06 | 2020-03-05 | Academia Sinica | Human iNKT cell activation using glycolipids with altered glycosyl groups |
CN105745528A (zh) | 2013-10-07 | 2016-07-06 | 赛卢拉研究公司 | 用于以数字方式对阵列上的特征进行计数的方法和系统 |
US9208864B2 (en) * | 2013-10-14 | 2015-12-08 | Toshiba America Electronic Components, Inc. | Semiconductor memory with integrated biologic element |
US10150818B2 (en) | 2014-01-16 | 2018-12-11 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
WO2015184009A1 (en) | 2014-05-27 | 2015-12-03 | Academia Sinica | Compositions and methods relating to universal glycoforms for enhanced antibody efficacy |
CA2937123A1 (en) | 2014-01-16 | 2015-07-23 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
WO2015148915A1 (en) | 2014-03-27 | 2015-10-01 | Academia Sinica | Reactive labelling compounds and uses thereof |
US10005847B2 (en) | 2014-05-27 | 2018-06-26 | Academia Sinica | Anti-HER2 glycoantibodies and uses thereof |
JP2017518989A (ja) | 2014-05-27 | 2017-07-13 | アカデミア シニカAcademia Sinica | 抗cd20糖操作抗体群およびその使用 |
US10118969B2 (en) | 2014-05-27 | 2018-11-06 | Academia Sinica | Compositions and methods relating to universal glycoforms for enhanced antibody efficacy |
US11332523B2 (en) | 2014-05-28 | 2022-05-17 | Academia Sinica | Anti-TNF-alpha glycoantibodies and uses thereof |
ES2786373T3 (es) | 2014-06-10 | 2020-10-09 | Biomatrica Inc | Estabilización de trombocitos a temperaturas ambiente |
AU2015315294B2 (en) | 2014-09-08 | 2020-09-17 | Academia Sinica | Human iNKT cell activation using glycolipids |
CN106999929A (zh) * | 2014-09-11 | 2017-08-01 | 克忧公司 | 用于检测和量化分析物的系统和方法 |
US9975965B2 (en) | 2015-01-16 | 2018-05-22 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
US10495645B2 (en) | 2015-01-16 | 2019-12-03 | Academia Sinica | Cancer markers and methods of use thereof |
EP3653292A1 (de) * | 2015-01-19 | 2020-05-20 | Hitachi Chemical Company, Ltd. | Trennmaterial |
EP3789766A1 (de) | 2015-01-24 | 2021-03-10 | Academia Sinica | Neuartige glycankonjugate und verfahren zur verwendung davon |
WO2016134078A1 (en) | 2015-02-19 | 2016-08-25 | Becton, Dickinson And Company | High-throughput single-cell analysis combining proteomic and genomic information |
CN107208158B (zh) | 2015-02-27 | 2022-01-28 | 贝克顿迪金森公司 | 空间上可寻址的分子条形编码 |
EP4180535A1 (de) | 2015-03-30 | 2023-05-17 | Becton, Dickinson and Company | Verfahren und zusammensetzungen für kombinatorische barcodierung |
WO2016172373A1 (en) | 2015-04-23 | 2016-10-27 | Cellular Research, Inc. | Methods and compositions for whole transcriptome amplification |
US11124823B2 (en) | 2015-06-01 | 2021-09-21 | Becton, Dickinson And Company | Methods for RNA quantification |
CN108026524A (zh) | 2015-09-11 | 2018-05-11 | 赛卢拉研究公司 | 用于核酸文库标准化的方法和组合物 |
EP3387411B1 (de) | 2015-12-08 | 2023-05-10 | Biomatrica, INC. | Verringerung der erythrozytensedimentationsrate |
US10336784B2 (en) | 2016-03-08 | 2019-07-02 | Academia Sinica | Methods for modular synthesis of N-glycans and arrays thereof |
AU2017261189B2 (en) | 2016-05-02 | 2023-02-09 | Becton, Dickinson And Company | Accurate molecular barcoding |
US10301677B2 (en) | 2016-05-25 | 2019-05-28 | Cellular Research, Inc. | Normalization of nucleic acid libraries |
US11397882B2 (en) | 2016-05-26 | 2022-07-26 | Becton, Dickinson And Company | Molecular label counting adjustment methods |
US10640763B2 (en) | 2016-05-31 | 2020-05-05 | Cellular Research, Inc. | Molecular indexing of internal sequences |
US10202641B2 (en) | 2016-05-31 | 2019-02-12 | Cellular Research, Inc. | Error correction in amplification of samples |
WO2017218777A1 (en) | 2016-06-17 | 2017-12-21 | California Institute Of Technology | Nucleic acid reactions and related methods and compositions |
US10391495B2 (en) * | 2016-08-22 | 2019-08-27 | Wisconsin Alumni Research Foundation | Deformable well and method |
KR102588027B1 (ko) | 2016-08-22 | 2023-10-12 | 초 파마 인크. | 항체, 결합 단편 및 사용 방법 |
US11460468B2 (en) | 2016-09-26 | 2022-10-04 | Becton, Dickinson And Company | Measurement of protein expression using reagents with barcoded oligonucleotide sequences |
KR102060306B1 (ko) * | 2016-10-05 | 2019-12-30 | 서울대학교산학협력단 | 저장, 보존 및 색인이 가능한 생화학 물질 운반체 및 이의 제조방법 |
EP3523043A1 (de) * | 2016-10-07 | 2019-08-14 | Boehringer Ingelheim Vetmedica GmbH | Verfahren zur steuerung einer analysevorrichtung und analysesystem |
KR20190077062A (ko) | 2016-11-08 | 2019-07-02 | 셀룰러 리서치, 인크. | 발현 프로파일 분류 방법 |
EP3538672A1 (de) | 2016-11-08 | 2019-09-18 | Cellular Research, Inc. | Verfahren zur klassifizierung von zellmarkern |
CN110573253B (zh) | 2017-01-13 | 2021-11-02 | 赛卢拉研究公司 | 流体通道的亲水涂层 |
US11319583B2 (en) | 2017-02-01 | 2022-05-03 | Becton, Dickinson And Company | Selective amplification using blocking oligonucleotides |
US10676779B2 (en) | 2017-06-05 | 2020-06-09 | Becton, Dickinson And Company | Sample indexing for single cells |
US11946095B2 (en) | 2017-12-19 | 2024-04-02 | Becton, Dickinson And Company | Particles associated with oligonucleotides |
SG11202007070VA (en) | 2018-01-30 | 2020-08-28 | Life Technologies Corp | Instruments, devices and consumables for use in a workflow of a smart molecular analysis system |
WO2019213237A1 (en) | 2018-05-03 | 2019-11-07 | Becton, Dickinson And Company | Molecular barcoding on opposite transcript ends |
CA3097976A1 (en) | 2018-05-03 | 2019-11-07 | Becton, Dickinson And Company | High throughput multiomics sample analysis |
JP2022511398A (ja) | 2018-10-01 | 2022-01-31 | ベクトン・ディキンソン・アンド・カンパニー | 5’転写物配列の決定 |
US11932849B2 (en) | 2018-11-08 | 2024-03-19 | Becton, Dickinson And Company | Whole transcriptome analysis of single cells using random priming |
CN113195717A (zh) | 2018-12-13 | 2021-07-30 | 贝克顿迪金森公司 | 单细胞全转录组分析中的选择性延伸 |
WO2020150356A1 (en) | 2019-01-16 | 2020-07-23 | Becton, Dickinson And Company | Polymerase chain reaction normalization through primer titration |
WO2020154247A1 (en) | 2019-01-23 | 2020-07-30 | Cellular Research, Inc. | Oligonucleotides associated with antibodies |
CN114051534A (zh) | 2019-07-22 | 2022-02-15 | 贝克顿迪金森公司 | 单细胞染色质免疫沉淀测序测定 |
US11591591B2 (en) * | 2019-08-21 | 2023-02-28 | New England Biolabs, Inc. | Isolation of high molecular weight DNA using beads |
EP4055160B1 (de) | 2019-11-08 | 2024-04-10 | Becton Dickinson and Company | Verwendung von random-rpiming zur gewinnung von v(d)j-informationen in voller länge für immunrepertoiresequenzierung |
US11649497B2 (en) | 2020-01-13 | 2023-05-16 | Becton, Dickinson And Company | Methods and compositions for quantitation of proteins and RNA |
US11918936B2 (en) | 2020-01-17 | 2024-03-05 | Waters Technologies Corporation | Performance and dynamic range for oligonucleotide bioanalysis through reduction of non specific binding |
CN115605614A (zh) | 2020-05-14 | 2023-01-13 | 贝克顿迪金森公司(Us) | 用于免疫组库谱分析的引物 |
CN111724841B (zh) * | 2020-06-04 | 2022-06-10 | 中国科学院上海微系统与信息技术研究所 | 一种基于生物蛋白的信息存储方法 |
US11932901B2 (en) | 2020-07-13 | 2024-03-19 | Becton, Dickinson And Company | Target enrichment using nucleic acid probes for scRNAseq |
CN112490685B (zh) * | 2020-10-13 | 2023-03-07 | 日月光半导体制造股份有限公司 | 天线封装结构及封装方法 |
EP4247967A1 (de) | 2020-11-20 | 2023-09-27 | Becton, Dickinson and Company | Profilierung von stark exprimierten und schwach exprimierten proteinen |
Family Cites Families (83)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3772200A (en) | 1971-04-30 | 1973-11-13 | Minnesota Mining & Mfg | Method of tagging with microparticles |
AT315542B (de) | 1972-09-27 | 1974-05-27 | Johannes Bancsich Dr | Probenträger und Vorrichtung zum Einschreiben und Auslesen desselben |
US4053433A (en) | 1975-02-19 | 1977-10-11 | Minnesota Mining And Manufacturing Company | Method of tagging with color-coded microparticles |
US4131064A (en) | 1977-07-15 | 1978-12-26 | Westinghouse Electric Corp. | Tagging particles which are easily detected by luminescent response, or magnetic pickup, or both |
US4390452A (en) | 1979-08-20 | 1983-06-28 | Minnesota Mining & Manufacturing Company | Microparticles with visual identifying means |
US4372745A (en) * | 1979-12-19 | 1983-02-08 | Electro-Nucleonics, Inc. | Chemical luminescence amplification substrate system for immunochemistry involving microencapsulated fluorescer |
GB2097144A (en) * | 1981-03-23 | 1982-10-27 | Tno | New method for identifying algae in water samples and apparatus for use in that method |
JPS58189558A (ja) * | 1982-04-28 | 1983-11-05 | Mochida Pharmaceut Co Ltd | 免疫学的測定用容器 |
FR2555744B1 (fr) * | 1983-11-30 | 1986-05-09 | Philips Ind Commerciale | Eprouvette avec moyens de memorisation des resultats d'analyse |
US4727020A (en) * | 1985-02-25 | 1988-02-23 | Becton, Dickinson And Company | Method for analysis of subpopulations of blood cells |
US4631211A (en) * | 1985-03-25 | 1986-12-23 | Scripps Clinic & Research Foundation | Means for sequential solid phase organic synthesis and methods using the same |
US4857893A (en) * | 1986-07-18 | 1989-08-15 | Bi Inc. | Single chip transponder device |
WO1989008264A1 (fr) * | 1988-03-04 | 1989-09-08 | Ballies Uwe W | Procede d'analyse automatique entierement selective du sang ou des composants du sang |
US4891254A (en) * | 1988-06-17 | 1990-01-02 | Bianco James S | Article with embedded optically-readable identification means and method for making same |
GB8816982D0 (en) * | 1988-07-16 | 1988-08-17 | Probus Biomedical Ltd | Bio-fluid assay apparatus |
DE3932428A1 (de) * | 1989-09-28 | 1991-04-11 | Argumens Gmbh | Vorrichtung zur drahtlosen messung einer lokalen physikalischen groesse |
US5092184A (en) * | 1989-12-22 | 1992-03-03 | Medical Research Institute Of The Mary Imogene Bassett Hospital | Cell staining system for flow cytometry |
AU8868091A (en) * | 1990-10-17 | 1992-05-20 | Jack Love | Identification and paternity determination by detecting presence or absence of multiple nucleic acid sequences |
US5228001A (en) * | 1991-01-23 | 1993-07-13 | Syracuse University | Optical random access memory |
US5639603A (en) | 1991-09-18 | 1997-06-17 | Affymax Technologies N.V. | Synthesizing and screening molecular diversity |
DE69217497T2 (de) * | 1991-09-18 | 1997-06-12 | Affymax Tech Nv | Verfahren zur synthese der verschiedenen sammlungen von oligomeren |
DE69220888T2 (de) * | 1991-11-05 | 1998-01-29 | Perkin Elmer Corp | Vorrichtung und Verfahren zur Herstellung von Biopolymeren |
US5213960A (en) * | 1992-03-09 | 1993-05-25 | Tanox Biosystems, Inc. | Methods for selecting low frequency antigen-specific single B lymphocytes |
JP3164403B2 (ja) * | 1992-03-27 | 2001-05-08 | オリンパス光学工業株式会社 | 自動分析装置 |
US5573905A (en) | 1992-03-30 | 1996-11-12 | The Scripps Research Institute | Encoded combinatorial chemical libraries |
DE4213065A1 (de) * | 1992-04-21 | 1993-10-28 | Norbert H L Dr Ing Koster | Selbstidentifizierende Telemetrievorrichtung |
US5288291A (en) * | 1992-08-12 | 1994-02-22 | Datapet, Inc. | Method and apparatus for simultaneously injecting a liquid and a transponder into an animal |
JP2541081B2 (ja) * | 1992-08-28 | 1996-10-09 | 日本電気株式会社 | バイオセンサ及びバイオセンサの製造・使用方法 |
US5585275A (en) * | 1992-09-02 | 1996-12-17 | Arris Pharmaceutical Corporation | Pilot apparatus for peptide synthesis and screening |
US5565324A (en) | 1992-10-01 | 1996-10-15 | The Trustees Of Columbia University In The City Of New York | Complex combinatorial chemical libraries encoded with tags |
DE4306563A1 (de) * | 1993-03-03 | 1994-09-08 | Jan Lichtenberg | Probenbehälter für zu analysierende Proben |
CA2139409C (en) * | 1993-05-17 | 2005-01-04 | Neil David Cook | Devices and methods for the measurement of cellular biochemical processes |
US6087186A (en) | 1993-07-16 | 2000-07-11 | Irori | Methods and apparatus for synthesizing labeled combinatorial chemistry libraries |
DE4326342A1 (de) * | 1993-08-05 | 1995-02-09 | Boehringer Mannheim Gmbh | Verfahren zur Analyse von Probenflüssigkeiten |
US6315953B1 (en) * | 1993-11-01 | 2001-11-13 | Nanogen, Inc. | Devices for molecular biological analysis and diagnostics including waveguides |
US5384025A (en) * | 1994-03-07 | 1995-01-24 | Applied Biosystems, Inc. | Notched spacer for slab-gel electrophoresis |
JPH07286953A (ja) * | 1994-04-19 | 1995-10-31 | Toa Medical Electronics Co Ltd | イメージングフローサイトメータ |
US5501954A (en) * | 1994-06-13 | 1996-03-26 | Genzyme Corporation | Method of detecting cellular material |
US5639428A (en) * | 1994-07-19 | 1997-06-17 | Becton Dickinson And Company | Method and apparatus for fully automated nucleic acid amplification, nucleic acid assay and immunoassay |
DE9416270U1 (de) * | 1994-10-10 | 1994-12-08 | Grieb Reinhard | Laborprobenbehälter |
US5985356A (en) | 1994-10-18 | 1999-11-16 | The Regents Of The University Of California | Combinatorial synthesis of novel materials |
US6100026A (en) | 1995-04-25 | 2000-08-08 | Irori | Matrices with memories and uses thereof |
US6329139B1 (en) | 1995-04-25 | 2001-12-11 | Discovery Partners International | Automated sorting system for matrices with memory |
US6340588B1 (en) | 1995-04-25 | 2002-01-22 | Discovery Partners International, Inc. | Matrices with memories |
US5741462A (en) | 1995-04-25 | 1998-04-21 | Irori | Remotely programmable matrices with memories |
US6352854B1 (en) | 1995-04-25 | 2002-03-05 | Discovery Partners International, Inc. | Remotely programmable matrices with memories |
US6017496A (en) | 1995-06-07 | 2000-01-25 | Irori | Matrices with memories and uses thereof |
US5961923A (en) | 1995-04-25 | 1999-10-05 | Irori | Matrices with memories and uses thereof |
US5874214A (en) | 1995-04-25 | 1999-02-23 | Irori | Remotely programmable matrices with memories |
KR19990008052A (ko) * | 1995-04-25 | 1999-01-25 | 마이클 피 노바 | 기억 장치를 갖는 원격적으로 프로그램 가능한 매트릭스 및 이의 용도 |
US6284459B1 (en) | 1995-04-25 | 2001-09-04 | Discovery Partners International | Solid support matrices with memories and combinatorial libraries therefrom |
US6319668B1 (en) | 1995-04-25 | 2001-11-20 | Discovery Partners International | Method for tagging and screening molecules |
US6025129A (en) | 1995-04-25 | 2000-02-15 | Irori | Remotely programmable matrices with memories and uses thereof |
US6331273B1 (en) | 1995-04-25 | 2001-12-18 | Discovery Partners International | Remotely programmable matrices with memories |
US6416714B1 (en) | 1995-04-25 | 2002-07-09 | Discovery Partners International, Inc. | Remotely programmable matrices with memories |
US5751629A (en) | 1995-04-25 | 1998-05-12 | Irori | Remotely programmable matrices with memories |
US5925562A (en) | 1995-04-25 | 1999-07-20 | Irori | Remotely programmable matrices with memories |
WO1996037777A1 (en) * | 1995-05-23 | 1996-11-28 | Nelson Randall W | Mass spectrometric immunoassay |
US5981180A (en) | 1995-10-11 | 1999-11-09 | Luminex Corporation | Multiplexed analysis of clinical specimens apparatus and methods |
US20030203390A1 (en) | 1995-10-26 | 2003-10-30 | Kaye Paul H. | Coded particles for process sequence tracking in combinatorial compound library preparation |
GB9521943D0 (en) | 1995-10-26 | 1996-01-03 | Univ Hertfordshire | Coded particles for process sequence tracking in combinatorial compound library preparation |
US5641634A (en) * | 1995-11-30 | 1997-06-24 | Mandecki; Wlodek | Electronically-indexed solid-phase assay for biomolecules |
JP2001519763A (ja) | 1996-03-22 | 2001-10-23 | オントジエン・コーポレイシヨン | 空間分散位置コード化組み合わせライブラリー合成方法 |
US6136274A (en) | 1996-10-07 | 2000-10-24 | Irori | Matrices with memories in automated drug discovery and units therefor |
US6449562B1 (en) | 1996-10-10 | 2002-09-10 | Luminex Corporation | Multiplexed analysis of clinical specimens apparatus and method |
US5858648A (en) | 1996-11-04 | 1999-01-12 | Sienna Biotech, Inc. | Assays using reference microparticles |
US6005691A (en) | 1996-12-11 | 1999-12-21 | Hewlett-Packard Company | High-security machine-readable holographic card |
US6023540A (en) | 1997-03-14 | 2000-02-08 | Trustees Of Tufts College | Fiber optic sensor with encoded microspheres |
US20020119580A1 (en) | 1997-04-17 | 2002-08-29 | Corless Anthony Robert | Radiofrequency encoded chemical library synthesis particles method |
US20020084329A1 (en) | 1997-07-16 | 2002-07-04 | Kaye Paul H. | Coded items for labeling objects |
JP3468750B2 (ja) | 1998-01-22 | 2003-11-17 | ルミネックス コーポレイション | 多数の蛍光シグナルを有する微小粒子 |
US6429027B1 (en) | 1998-12-28 | 2002-08-06 | Illumina, Inc. | Composite arrays utilizing microspheres |
US6908737B2 (en) | 1999-04-15 | 2005-06-21 | Vitra Bioscience, Inc. | Systems and methods of conducting multiplexed experiments |
US20030134330A1 (en) | 1999-04-15 | 2003-07-17 | Ilya Ravkin | Chemical-library composition and method |
US20040018485A1 (en) | 1999-04-15 | 2004-01-29 | Ilya Ravkin | Multiplexed analysis of cells |
US20030129654A1 (en) | 1999-04-15 | 2003-07-10 | Ilya Ravkin | Coded particles for multiplexed analysis of biological samples |
US7253435B2 (en) | 1999-04-15 | 2007-08-07 | Millipore Corporation | Particles with light-polarizing codes |
US6544732B1 (en) | 1999-05-20 | 2003-04-08 | Illumina, Inc. | Encoding and decoding of array sensors utilizing nanocrystals |
US6649414B1 (en) | 1999-08-17 | 2003-11-18 | Luminex Corporation | Microparticles with multiple fluorescent signals and methods of using same |
US7338773B2 (en) | 2000-04-14 | 2008-03-04 | Millipore Corporation | Multiplexed assays of cell migration |
JP2004537712A (ja) | 2000-10-18 | 2004-12-16 | バーチャル・アレイズ・インコーポレーテッド | 多重細胞分析システム |
US20040069857A1 (en) * | 2000-10-19 | 2004-04-15 | Leblans Marc Jan Rene | Method and device for the manipulation of microcarriers for an identification purpose |
US7842246B2 (en) * | 2001-06-29 | 2010-11-30 | Meso Scale Technologies, Llc | Assay plates, reader systems and methods for luminescence test measurements |
-
1996
- 1996-04-25 KR KR1019970707576A patent/KR19990008052A/ko not_active Application Discontinuation
- 1996-04-25 EP EP96916437A patent/EP0822861B1/de not_active Expired - Lifetime
- 1996-04-25 CA CA002216645A patent/CA2216645A1/en not_active Abandoned
- 1996-04-25 CN CN96193374A patent/CN1181720A/zh active Pending
- 1996-04-25 DE DE69630881T patent/DE69630881T2/de not_active Expired - Lifetime
- 1996-04-25 AU AU59185/96A patent/AU707444B2/en not_active Ceased
- 1996-04-25 AT AT96916437T patent/ATE254965T1/de not_active IP Right Cessation
- 1996-04-25 JP JP8530562A patent/JPH11511238A/ja active Pending
- 1996-04-25 EA EA199700257A patent/EA199700257A1/ru unknown
- 1996-04-25 WO PCT/US1996/006145 patent/WO1996036436A1/en active IP Right Grant
-
2004
- 2004-12-14 US US11/011,452 patent/US7935659B2/en not_active Expired - Fee Related
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2011
- 2011-05-02 US US13/099,198 patent/US8219327B2/en not_active Expired - Fee Related
- 2011-06-10 US US13/158,302 patent/US20110237459A1/en not_active Abandoned
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2012
- 2012-05-23 US US13/478,689 patent/US20120238466A1/en not_active Abandoned
- 2012-12-07 US US13/708,778 patent/US20130090260A1/en not_active Abandoned
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JPH11511238A (ja) | 1999-09-28 |
EA199700257A1 (ru) | 1998-12-24 |
US7935659B2 (en) | 2011-05-03 |
US20090226891A2 (en) | 2009-09-10 |
EP0822861B1 (de) | 2003-11-26 |
CN1181720A (zh) | 1998-05-13 |
AU707444B2 (en) | 1999-07-08 |
US20110237459A1 (en) | 2011-09-29 |
KR19990008052A (ko) | 1999-01-25 |
US20110212857A1 (en) | 2011-09-01 |
WO1996036436A1 (en) | 1996-11-21 |
CA2216645A1 (en) | 1996-11-21 |
US8219327B2 (en) | 2012-07-10 |
US20120238466A1 (en) | 2012-09-20 |
US20070248957A1 (en) | 2007-10-25 |
US20130090260A1 (en) | 2013-04-11 |
DE69630881T2 (de) | 2004-09-02 |
ATE254965T1 (de) | 2003-12-15 |
AU5918596A (en) | 1996-11-29 |
EP0822861A1 (de) | 1998-02-11 |
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