DE69533099D1 - Zytoanalysator - Google Patents

Zytoanalysator

Info

Publication number
DE69533099D1
DE69533099D1 DE69533099T DE69533099T DE69533099D1 DE 69533099 D1 DE69533099 D1 DE 69533099D1 DE 69533099 T DE69533099 T DE 69533099T DE 69533099 T DE69533099 T DE 69533099T DE 69533099 D1 DE69533099 D1 DE 69533099D1
Authority
DE
Germany
Prior art keywords
cytoanalyzer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69533099T
Other languages
English (en)
Other versions
DE69533099T2 (de
Inventor
Kaoru Takarada
Yoshihiro Hyosa
Takashi Sakata
Chihiro Kouzuki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sysmex Corp
Original Assignee
Sysmex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sysmex Corp filed Critical Sysmex Corp
Application granted granted Critical
Publication of DE69533099D1 publication Critical patent/DE69533099D1/de
Publication of DE69533099T2 publication Critical patent/DE69533099T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Electro-optical investigation, e.g. flow cytometers
    • G01N15/1456Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Electro-optical investigation, e.g. flow cytometers
    • G01N15/1434Electro-optical investigation, e.g. flow cytometers using an analyser being characterised by its optical arrangement
    • G01N2015/016
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Electro-optical investigation, e.g. flow cytometers
    • G01N2015/1477Multiparameters
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Electro-optical investigation, e.g. flow cytometers
    • G01N2015/1486Counting the particles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47Scattering, i.e. diffuse reflection
    • G01N2021/4704Angular selective
    • G01N2021/4711Multiangle measurement
    • G01N2021/4716Using a ring of sensors, or a combination of diaphragm and sensors; Annular sensor
DE69533099T 1994-08-08 1995-08-04 Zytoanalysator Expired - Fee Related DE69533099T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP18614894 1994-08-08
JP18614894A JP3375203B2 (ja) 1994-08-08 1994-08-08 細胞分析装置

Publications (2)

Publication Number Publication Date
DE69533099D1 true DE69533099D1 (de) 2004-07-08
DE69533099T2 DE69533099T2 (de) 2005-01-05

Family

ID=16183227

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69533099T Expired - Fee Related DE69533099T2 (de) 1994-08-08 1995-08-04 Zytoanalysator

Country Status (9)

Country Link
US (1) US5737078A (de)
EP (1) EP0696731B1 (de)
JP (1) JP3375203B2 (de)
KR (1) KR100395992B1 (de)
CN (1) CN1116708A (de)
AU (1) AU2832295A (de)
CA (1) CA2155403A1 (de)
DE (1) DE69533099T2 (de)
TW (1) TW294782B (de)

Families Citing this family (81)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6509192B1 (en) * 1992-02-24 2003-01-21 Coulter International Corp. Quality control method
US6061131A (en) * 1997-01-08 2000-05-09 Horiba, Ltd. Optical axis adjustment apparatus and method for particle size distribution measuring equipment
EP1017987B1 (de) 1997-01-31 2005-06-15 The Horticulture And Food Research Institute Of New Zealand Limited Optische vorrichtung und methode
EP1396737A3 (de) * 1997-03-11 2004-12-29 Nihon Kohden Corporation Teilchenanalysator und Linse zusammengesetzt aus mehreren Linsenelementen mit unterschiedlichen Brennpunkten
US5917584A (en) * 1997-11-21 1999-06-29 Coulter International Corp. Method for differentiation of nucleated red blood cells
US5874310A (en) * 1997-11-21 1999-02-23 Coulter International Corp. Method for differentiation of nucleated red blood cells
US5874311A (en) * 1997-11-21 1999-02-23 Coulter International Corp. Method for differentiation of reticulocytes in blood
US6149867A (en) 1997-12-31 2000-11-21 Xy, Inc. Sheath fluids and collection systems for sex-specific cytometer sorting of sperm
JP3393817B2 (ja) 1998-10-16 2003-04-07 株式会社堀場製作所 粒径分布測定装置
JP3415475B2 (ja) * 1999-04-16 2003-06-09 株式会社堀場製作所 粒子径分布測定装置
JP3817091B2 (ja) * 1999-07-02 2006-08-30 テルモ株式会社 細胞数測定装置
US7208265B1 (en) 1999-11-24 2007-04-24 Xy, Inc. Method of cryopreserving selected sperm cells
JP3818867B2 (ja) * 2000-05-12 2006-09-06 リオン株式会社 光散乱式粒子検出器
US6700130B2 (en) * 2001-06-29 2004-03-02 Honeywell International Inc. Optical detection system for flow cytometry
US6784981B1 (en) 2000-06-02 2004-08-31 Idexx Laboratories, Inc. Flow cytometry-based hematology system
KR100675103B1 (ko) * 2000-07-18 2007-01-29 주식회사 태산솔루젼스 운반체에 대한 세포의 부착력 측정장치 및 그 방법
US20020028434A1 (en) * 2000-09-06 2002-03-07 Guava Technologies, Inc. Particle or cell analyzer and method
CA2468774C (en) 2000-11-29 2015-06-30 George E. Seidel System for in-vitro fertilization with spermatozoa separated into x-chromosome and y-chromosome bearing populations
US7713687B2 (en) 2000-11-29 2010-05-11 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
DE60218074T2 (de) 2001-03-29 2008-02-07 Sysmex Corp. Durchflusszytometer
JP4763159B2 (ja) * 2001-06-15 2011-08-31 シスメックス株式会社 フローサイトメータ
JP4659252B2 (ja) * 2001-03-29 2011-03-30 シスメックス株式会社 フローサイトメータ
WO2002092247A1 (en) * 2001-05-17 2002-11-21 Cytomation, Inc. Flow cytometer with active automated optical alignment system
US6519033B1 (en) 2001-11-19 2003-02-11 Point Source Technologies, Llc Identification of particles in fluid
US6774995B2 (en) 2001-08-03 2004-08-10 Pointsource Technologies, Llc Identification of particles in fluid
US6573992B1 (en) 2001-11-13 2003-06-03 Pointsource Technologies, Llc Plano convex fluid carrier for scattering correction
US6590652B2 (en) 2001-11-02 2003-07-08 Pointsource Technologies, Inc. Flow through light scattering device
US6628386B2 (en) 2001-12-12 2003-09-30 Pointsource Technologies, Llc Particle detection beam
US6930769B1 (en) 2002-03-21 2005-08-16 Pointsource Technologies, Llc Optical sensor module tester
US7057724B1 (en) 2002-03-21 2006-06-06 Institute Of Critical Care Medicine Particulate info to field units
US6972424B1 (en) 2002-04-16 2005-12-06 Pointsource Technologies, Llc High detection rate particle identifier
US7487061B2 (en) 2002-05-23 2009-02-03 Sysmex Corporation Sample analyzer
MXPA05001100A (es) 2002-08-01 2005-04-28 Xy Inc Sistema de separacion de baja presion para celulas de esperma.
US8486618B2 (en) 2002-08-01 2013-07-16 Xy, Llc Heterogeneous inseminate system
AU2003265471B2 (en) 2002-08-15 2009-08-06 Xy, Llc. High resolution flow cytometer
US7169548B2 (en) 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
JP4614947B2 (ja) 2003-03-28 2011-01-19 イングラン・リミテッド・ライアビリティ・カンパニー 粒子を仕分けるためおよび性別で仕分けられた動物の精子を提供するための装置、および方法
US7092078B2 (en) 2003-03-31 2006-08-15 Nihon Kohden Corporation Flow cytometer for classifying leukocytes and method for determining detection angle range of the same
US6819421B1 (en) 2003-04-11 2004-11-16 Point Source Technologies, Llc Detection of new species of particles
ES2541121T3 (es) 2003-05-15 2015-07-16 Xy, Llc Clasificación eficiente de células haploides por sistemas de citometría de flujo
JP4568578B2 (ja) * 2004-02-19 2010-10-27 ニュースキン インターナショナル インコーポレイテッド バイオフォトニック・フィードバック制御装置及び方法
US10620105B2 (en) * 2004-03-06 2020-04-14 Michael Trainer Methods and apparatus for determining characteristics of particles from scattered light
PL2151243T3 (pl) 2004-03-29 2013-03-29 Inguran Llc Zawiesiny plemników do sortowania na populacje wzbogacone w niosące chromosom X lub Y
CN1981187A (zh) * 2004-05-14 2007-06-13 霍尼韦尔国际公司 便携式样本分析仪盒
AU2005266930B2 (en) 2004-07-22 2010-09-16 Inguran, Llc Process for enriching a population of sperm cells
CN101151517A (zh) * 2005-03-29 2008-03-26 希森美康株式会社 鉴别癌症/异型细胞和粒子团的方法及细胞分析仪
JP4721338B2 (ja) * 2005-10-20 2011-07-13 リコーエレメックス株式会社 液吐出不良検出装置、およびインクジェット記録装置
CN101000306B (zh) 2006-01-09 2010-11-17 深圳迈瑞生物医疗电子股份有限公司 细胞分析仪
US8088110B2 (en) 2006-11-17 2012-01-03 Bencha International Group Inc. Automatically retractable safety injector for non-liquid material
CN101236150B (zh) 2007-02-02 2012-09-05 深圳迈瑞生物医疗电子股份有限公司 用于基于流式细胞术的仪器的光电传感器及其照射单元
CN101498646B (zh) * 2008-02-03 2014-06-11 深圳迈瑞生物医疗电子股份有限公司 前向散射光信号探测装置与方法及细胞或粒子分析仪
CN104965068B (zh) 2008-05-09 2017-12-08 希森美康株式会社 血液分析装置,血液分析方法及溶血剂
ITFI20080095A1 (it) 2008-05-15 2009-11-16 Oglio Giorgio Dall Metodo e dispositivo di compensazione per segnali di luce di scattering generati da interazione di luce con particelle o cellule biologiche in movimento in correnti fluide come nella citometria a flusso.
EP2335079B1 (de) * 2008-09-25 2015-07-01 Agilent Technologies, Inc. Lichtstreuende durchflusszellenvorrichtung
JP5304456B2 (ja) * 2009-06-10 2013-10-02 ソニー株式会社 微小粒子測定装置
JP5365465B2 (ja) * 2009-10-15 2013-12-11 株式会社リコー 液吐出不良検出装置およびインクジェット記録装置
JP5537347B2 (ja) * 2009-11-30 2014-07-02 シスメックス株式会社 粒子分析装置
JP5887275B2 (ja) * 2009-12-04 2016-03-16 ライフ テクノロジーズ コーポレーション アコースティックフローサイトメトリーのための装置、システム、方法、およびコンピュータ読み取り可能な媒体
KR101156863B1 (ko) * 2010-06-28 2012-07-11 삼성전기주식회사 세포 수 계수용 액적 토출 장치
JP2012047464A (ja) * 2010-08-24 2012-03-08 Sony Corp 微小粒子測定装置及び光軸補正方法
US9513206B2 (en) 2013-03-29 2016-12-06 Sysmex Corporation Particle measuring apparatus
JP6100658B2 (ja) 2013-03-29 2017-03-22 シスメックス株式会社 血球分析装置および血球分析方法
JP6121319B2 (ja) * 2013-03-29 2017-04-26 シスメックス株式会社 粒子測定装置、照射光学系および照射位置調整方法
CN103278440A (zh) * 2013-05-14 2013-09-04 桂林优利特医疗电子有限公司 细胞散射光多位置检测方法及细胞分析仪
CN110068678A (zh) * 2013-05-31 2019-07-30 积水医疗株式会社 凝集免疫测定法
WO2015106220A1 (en) * 2014-01-10 2015-07-16 Glucovista, Inc. Non-invasive system and method for measuring a substance concentration
WO2016109355A1 (en) 2014-12-23 2016-07-07 Bribbla Dynamics Llc Optical inspection system and method including accounting for variations of optical path length within a sample
US10718931B2 (en) 2014-12-23 2020-07-21 Apple Inc. Confocal inspection system having averaged illumination and averaged collection paths
CN105434111A (zh) * 2015-04-30 2016-03-30 深圳市远嘉科技有限公司 一种智能检测卫生巾
EP4148416A1 (de) 2015-09-01 2023-03-15 Apple Inc. System zur durchführung einer messung und verfahren zur durchführung einer messung einer probe mit einer vorrichtung
CN105547970B (zh) * 2015-12-22 2018-09-18 中国科学院苏州生物医学工程技术研究所 一种流式细胞仪激发光源系统及校正方法
WO2017184420A1 (en) 2016-04-21 2017-10-26 Bribbla Dynamics Llc Optical system for reference switching
CN106769805B (zh) * 2017-01-22 2019-06-18 江西特康科技有限公司 细胞计数分类装置
EP3624679B1 (de) 2017-05-19 2023-09-13 GlucoVista Inc. Vorrichtungen und verfahren zur nir-glukosekonzentrationsüberwachung
EP3688446A2 (de) 2017-09-29 2020-08-05 Apple Inc. Optische auflösungspfadabtastarchitekturen
US10914913B2 (en) 2018-03-30 2021-02-09 Idexx Laboratories, Inc. Flow cytometer, laser optics assembly thereof, and methods of assembling the same
WO2019207988A1 (ja) * 2018-04-25 2019-10-31 ソニー株式会社 微小粒子分取装置及び微小粒子分取方法
CN109357992B (zh) * 2018-11-09 2021-11-02 赛默飞世尔(上海)仪器有限公司 用于对光束进行整形的光学系统及流式细胞仪
KR20220005478A (ko) * 2019-04-25 2022-01-13 파티클 머슈어링 시스템즈, 인크. 축상 입자 검출 및/또는 차동 검출을 위한 입자 검출 시스템 및 방법
AU2021293085A1 (en) 2020-06-17 2023-02-16 Idexx Laboratories Inc. Flow cytometer and laser optics assembly thereof
KR20230043191A (ko) 2020-09-09 2023-03-30 애플 인크. 노이즈 완화를 위한 광학 시스템

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2195907A5 (de) * 1972-08-10 1974-03-08 Meric Jean Paul
US4595291A (en) * 1982-10-15 1986-06-17 Tokyo Shibaura Denki Kabushiki Kaisha Particle diameter measuring device
US4596035A (en) * 1983-06-27 1986-06-17 Ortho Diagnostic Systems Inc. Methods for enumerating 3-part white cell differential clusters
EP0172242A1 (de) * 1984-02-29 1986-02-26 Research Corporation Durchflusszellanalysegerät
JPS60260830A (ja) * 1984-06-07 1985-12-24 Fujisawa Pharmaceut Co Ltd 細胞自動分析装置における細胞照射光源装置
KR970007077B1 (ko) * 1987-03-13 1997-05-02 코울터 일렉트로닉스 인커퍼레이티드 광산란 기술을 이용한 다중-부분식별 분석 방법
JP2715604B2 (ja) * 1989-12-18 1998-02-18 株式会社島津製作所 レーザ回折・散乱式粒度分布測定装置
JP3049254B2 (ja) 1990-02-08 2000-06-05 シスメックス株式会社 2種類の光源を備えた光学式粒子分析装置
US5416580A (en) * 1993-07-07 1995-05-16 General Signal Corporation Methods and apparatus for determining small particle size distribution utilizing multiple light beams
JP3467310B2 (ja) * 1994-04-21 2003-11-17 シスメックス株式会社 白血球分析用試薬及び白血球の分類方法
US5467193A (en) * 1994-08-08 1995-11-14 Laewen; Arne H. Target device and use thereof for aligning light beams utilizing cross-hair light beams

Also Published As

Publication number Publication date
EP0696731A2 (de) 1996-02-14
JPH0850089A (ja) 1996-02-20
JP3375203B2 (ja) 2003-02-10
CA2155403A1 (en) 1996-02-09
KR960008303A (ko) 1996-03-22
CN1116708A (zh) 1996-02-14
EP0696731B1 (de) 2004-06-02
TW294782B (de) 1997-01-01
US5737078A (en) 1998-04-07
KR100395992B1 (ko) 2003-11-14
DE69533099T2 (de) 2005-01-05
AU2832295A (en) 1996-02-22
EP0696731A3 (de) 1997-10-15

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