DE69432186D1 - Verfahren zur herstellung stabiler arzneimittel - Google Patents
Verfahren zur herstellung stabiler arzneimittelInfo
- Publication number
- DE69432186D1 DE69432186D1 DE69432186T DE69432186T DE69432186D1 DE 69432186 D1 DE69432186 D1 DE 69432186D1 DE 69432186 T DE69432186 T DE 69432186T DE 69432186 T DE69432186 T DE 69432186T DE 69432186 D1 DE69432186 D1 DE 69432186D1
- Authority
- DE
- Germany
- Prior art keywords
- medicinal products
- producing stable
- stable medicinal
- producing
- products
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP28912793 | 1993-11-18 | ||
JP28912793 | 1993-11-18 | ||
PCT/JP1994/001936 WO1995013794A1 (fr) | 1993-11-18 | 1994-11-17 | Procede pour produire une composition de medicament stable, et preparation pharmaceutique |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69432186D1 true DE69432186D1 (de) | 2003-04-03 |
DE69432186T2 DE69432186T2 (de) | 2004-05-06 |
Family
ID=17739116
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69432186T Expired - Fee Related DE69432186T2 (de) | 1993-11-18 | 1994-11-17 | Verfahren zur herstellung stabiler arzneimittel |
Country Status (4)
Country | Link |
---|---|
US (1) | US5688510A (de) |
EP (1) | EP0729748B1 (de) |
DE (1) | DE69432186T2 (de) |
WO (1) | WO1995013794A1 (de) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW474824B (en) | 1996-09-13 | 2002-02-01 | Basf Ag | The production of solid pharmaceutical forms |
CA2254078A1 (en) * | 1997-03-11 | 1998-09-17 | Hexal Ag | Solid, non-deliquescent formulations of sodium valproate |
CA2316989A1 (en) * | 1997-12-24 | 1999-07-08 | Interneuron Pharmaceuticals, Inc. | Hyperhydrated citicoline, process and use |
WO1999034780A1 (de) * | 1998-01-12 | 1999-07-15 | Bühler AG | Verfahren und vorrichtung zum verkapseln von wirkstoffen |
DE19855440A1 (de) * | 1998-12-01 | 2000-06-08 | Basf Ag | Verfahren zum Herstellen fester Darreichungsformen mittels Schmelzextrusion |
DE19913606A1 (de) * | 1999-03-25 | 2000-09-28 | Basf Ag | Pulverförmige Solubilisationshilfsstoffe für feste pharmazeutische Darreichungsformen |
DE19918325A1 (de) * | 1999-04-22 | 2000-10-26 | Euro Celtique Sa | Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion |
DE29916014U1 (de) | 1999-09-16 | 2001-02-08 | Akh Arzneimittelkontor Hamburg | Pharmazeutische Zusammensetzung, umfassend Eukalyptus- und Orangenöl |
RU2277416C2 (ru) * | 2000-03-21 | 2006-06-10 | Ниппон Синяку Ко., Лтд. | Препараты для перорального введения с замедленным высвобождением |
TWI290053B (en) * | 2000-09-19 | 2007-11-21 | Daiichi Seiyaku Co | Medicinal composition for preventing the generation of a disagreeable taste |
FR2814366A1 (fr) * | 2000-09-22 | 2002-03-29 | Rhodia Chimie Sa | Procede de granulation de matieres actives par extrusion basse pression pour l'obtention de granules directement compressibles |
US6855333B1 (en) | 2000-10-03 | 2005-02-15 | Mutual Pharmaceutical Co., Inc. | Stabilization of solid thyroid drug formulations |
US6979462B1 (en) * | 2000-10-03 | 2005-12-27 | Mutual Pharmaceutical Co., Inc. | Stabilization of solid drug formulations |
KR20050044459A (ko) * | 2001-11-13 | 2005-05-12 | 파마시아 코포레이션 | 파레콕시브 등의 설폰아미드 선구약물의 경구 투여 형태 |
AU2003228268A1 (en) * | 2002-03-04 | 2003-09-22 | Buckley, Chad | Improved polyvinyl alcohol film and method of producing the same |
WO2003077827A1 (fr) * | 2002-03-19 | 2003-09-25 | Nippon Shinyaku Co., Ltd. | Procede de production de medicament solide en dispersion |
BR0317392A (pt) * | 2002-12-19 | 2005-12-20 | Pharmacia Corp | Formulação não-higroscópica incluindo uma droga higroscópica |
JP4945108B2 (ja) * | 2004-09-24 | 2012-06-06 | 興和株式会社 | イソソルビド製剤 |
KR20130061199A (ko) * | 2005-10-31 | 2013-06-10 | 교와 가부시키가이샤 | 이소소르비드 제제 |
US9029427B2 (en) * | 2005-11-11 | 2015-05-12 | Asahi Kasei Chemicals Corporation | Controlled release solid preparation |
KR20080112285A (ko) | 2006-03-28 | 2008-12-24 | 자블린 파머슈티칼스 인코포레이티드 | 저 복용량의 디클로페낙 및 베타-사이클로덱스트린 제형 |
US8299079B2 (en) | 2009-05-22 | 2012-10-30 | Kaufman Herbert E | Preparations and methods for ameliorating or reducing presbyopia |
PL2672981T3 (pl) * | 2011-02-11 | 2018-09-28 | Zx Pharma, Llc | Wielocząstkowe preparaty l-mentolu i powiązane sposoby |
US8911780B2 (en) | 2011-02-11 | 2014-12-16 | Zx Pharma, Llc | Multiparticulate L-menthol formulations and related methods |
US8808736B2 (en) | 2011-02-11 | 2014-08-19 | Zx Pharma, Llc | Enteric coated multiparticulate controlled release peppermint oil composition and related methods |
JP6227546B2 (ja) * | 2012-10-26 | 2017-11-08 | 田辺三菱製薬株式会社 | メントールウィスカーの析出を抑制する方法 |
AU2013387678B2 (en) | 2013-04-23 | 2015-04-16 | Sociétés des Produits Nestlé S.A. | Enteric coated multiparticulate controlled release peppermint oil composition and related methods |
EP3445337B1 (de) * | 2016-04-22 | 2021-03-24 | University Of Mississippi | Doppelschraubentrockengranulierung zur herstellung fester formulierungen |
CN107285476A (zh) * | 2017-05-27 | 2017-10-24 | 防城港市渔业技术推广站 | 一种养虾池塘专用水质改良剂 |
CN108420797B (zh) * | 2018-05-09 | 2022-05-03 | 南京海融制药有限公司 | 维生素d类似物制剂及其制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4764378A (en) * | 1986-02-10 | 1988-08-16 | Zetachron, Inc. | Buccal drug dosage form |
DE3612212A1 (de) * | 1986-04-11 | 1987-10-15 | Basf Ag | Verfahren zur herstellung von festen pharmazeutischen formen |
DK0580860T4 (da) * | 1991-04-16 | 2005-03-21 | Nippon Shinyaku Co Ltd | Fremgangsmåde til fremstilling af en fast dispersion |
SG43179A1 (en) * | 1991-12-18 | 1997-10-17 | Warner Lambert Co | A process for the prepatation of a solid dispersion |
ES2145063T3 (es) * | 1992-10-14 | 2000-07-01 | Nippon Shinyaku Co Ltd | Procedimiento de dislocacion del estado cristalino. |
DE69332291T2 (de) * | 1992-10-16 | 2003-07-31 | Nippon Shinyaku Co Ltd | Verfahren zur herstellung von wachsmatrizes |
EP1123660A3 (de) * | 1993-04-16 | 2004-01-07 | McCORMICK & COMPANY, INC. | Verkapselungszusammensetzungen |
-
1994
- 1994-11-17 DE DE69432186T patent/DE69432186T2/de not_active Expired - Fee Related
- 1994-11-17 US US08/648,174 patent/US5688510A/en not_active Expired - Fee Related
- 1994-11-17 EP EP95900907A patent/EP0729748B1/de not_active Expired - Lifetime
- 1994-11-17 WO PCT/JP1994/001936 patent/WO1995013794A1/ja active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
EP0729748A4 (de) | 1997-09-10 |
DE69432186T2 (de) | 2004-05-06 |
EP0729748B1 (de) | 2003-02-26 |
US5688510A (en) | 1997-11-18 |
WO1995013794A1 (fr) | 1995-05-26 |
EP0729748A1 (de) | 1996-09-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8332 | No legal effect for de | ||
8370 | Indication of lapse of patent is to be deleted | ||
8339 | Ceased/non-payment of the annual fee |