DE69432186D1 - Verfahren zur herstellung stabiler arzneimittel - Google Patents

Verfahren zur herstellung stabiler arzneimittel

Info

Publication number
DE69432186D1
DE69432186D1 DE69432186T DE69432186T DE69432186D1 DE 69432186 D1 DE69432186 D1 DE 69432186D1 DE 69432186 T DE69432186 T DE 69432186T DE 69432186 T DE69432186 T DE 69432186T DE 69432186 D1 DE69432186 D1 DE 69432186D1
Authority
DE
Germany
Prior art keywords
medicinal products
producing stable
stable medicinal
producing
products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69432186T
Other languages
English (en)
Other versions
DE69432186T2 (de
Inventor
Kouichi Nakamichi
Shougo Izumi
Hiroyuki Yasuura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Shinyaku Co Ltd
Original Assignee
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Application granted granted Critical
Publication of DE69432186D1 publication Critical patent/DE69432186D1/de
Publication of DE69432186T2 publication Critical patent/DE69432186T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
DE69432186T 1993-11-18 1994-11-17 Verfahren zur herstellung stabiler arzneimittel Expired - Fee Related DE69432186T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP28912793 1993-11-18
JP28912793 1993-11-18
PCT/JP1994/001936 WO1995013794A1 (fr) 1993-11-18 1994-11-17 Procede pour produire une composition de medicament stable, et preparation pharmaceutique

Publications (2)

Publication Number Publication Date
DE69432186D1 true DE69432186D1 (de) 2003-04-03
DE69432186T2 DE69432186T2 (de) 2004-05-06

Family

ID=17739116

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69432186T Expired - Fee Related DE69432186T2 (de) 1993-11-18 1994-11-17 Verfahren zur herstellung stabiler arzneimittel

Country Status (4)

Country Link
US (1) US5688510A (de)
EP (1) EP0729748B1 (de)
DE (1) DE69432186T2 (de)
WO (1) WO1995013794A1 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW474824B (en) 1996-09-13 2002-02-01 Basf Ag The production of solid pharmaceutical forms
CA2254078A1 (en) * 1997-03-11 1998-09-17 Hexal Ag Solid, non-deliquescent formulations of sodium valproate
CA2316989A1 (en) * 1997-12-24 1999-07-08 Interneuron Pharmaceuticals, Inc. Hyperhydrated citicoline, process and use
WO1999034780A1 (de) * 1998-01-12 1999-07-15 Bühler AG Verfahren und vorrichtung zum verkapseln von wirkstoffen
DE19855440A1 (de) * 1998-12-01 2000-06-08 Basf Ag Verfahren zum Herstellen fester Darreichungsformen mittels Schmelzextrusion
DE19913606A1 (de) * 1999-03-25 2000-09-28 Basf Ag Pulverförmige Solubilisationshilfsstoffe für feste pharmazeutische Darreichungsformen
DE19918325A1 (de) * 1999-04-22 2000-10-26 Euro Celtique Sa Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
DE29916014U1 (de) 1999-09-16 2001-02-08 Akh Arzneimittelkontor Hamburg Pharmazeutische Zusammensetzung, umfassend Eukalyptus- und Orangenöl
RU2277416C2 (ru) * 2000-03-21 2006-06-10 Ниппон Синяку Ко., Лтд. Препараты для перорального введения с замедленным высвобождением
TWI290053B (en) * 2000-09-19 2007-11-21 Daiichi Seiyaku Co Medicinal composition for preventing the generation of a disagreeable taste
FR2814366A1 (fr) * 2000-09-22 2002-03-29 Rhodia Chimie Sa Procede de granulation de matieres actives par extrusion basse pression pour l'obtention de granules directement compressibles
US6855333B1 (en) 2000-10-03 2005-02-15 Mutual Pharmaceutical Co., Inc. Stabilization of solid thyroid drug formulations
US6979462B1 (en) * 2000-10-03 2005-12-27 Mutual Pharmaceutical Co., Inc. Stabilization of solid drug formulations
KR20050044459A (ko) * 2001-11-13 2005-05-12 파마시아 코포레이션 파레콕시브 등의 설폰아미드 선구약물의 경구 투여 형태
AU2003228268A1 (en) * 2002-03-04 2003-09-22 Buckley, Chad Improved polyvinyl alcohol film and method of producing the same
WO2003077827A1 (fr) * 2002-03-19 2003-09-25 Nippon Shinyaku Co., Ltd. Procede de production de medicament solide en dispersion
BR0317392A (pt) * 2002-12-19 2005-12-20 Pharmacia Corp Formulação não-higroscópica incluindo uma droga higroscópica
JP4945108B2 (ja) * 2004-09-24 2012-06-06 興和株式会社 イソソルビド製剤
KR20130061199A (ko) * 2005-10-31 2013-06-10 교와 가부시키가이샤 이소소르비드 제제
US9029427B2 (en) * 2005-11-11 2015-05-12 Asahi Kasei Chemicals Corporation Controlled release solid preparation
KR20080112285A (ko) 2006-03-28 2008-12-24 자블린 파머슈티칼스 인코포레이티드 저 복용량의 디클로페낙 및 베타-사이클로덱스트린 제형
US8299079B2 (en) 2009-05-22 2012-10-30 Kaufman Herbert E Preparations and methods for ameliorating or reducing presbyopia
PL2672981T3 (pl) * 2011-02-11 2018-09-28 Zx Pharma, Llc Wielocząstkowe preparaty l-mentolu i powiązane sposoby
US8911780B2 (en) 2011-02-11 2014-12-16 Zx Pharma, Llc Multiparticulate L-menthol formulations and related methods
US8808736B2 (en) 2011-02-11 2014-08-19 Zx Pharma, Llc Enteric coated multiparticulate controlled release peppermint oil composition and related methods
JP6227546B2 (ja) * 2012-10-26 2017-11-08 田辺三菱製薬株式会社 メントールウィスカーの析出を抑制する方法
AU2013387678B2 (en) 2013-04-23 2015-04-16 Sociétés des Produits Nestlé S.A. Enteric coated multiparticulate controlled release peppermint oil composition and related methods
EP3445337B1 (de) * 2016-04-22 2021-03-24 University Of Mississippi Doppelschraubentrockengranulierung zur herstellung fester formulierungen
CN107285476A (zh) * 2017-05-27 2017-10-24 防城港市渔业技术推广站 一种养虾池塘专用水质改良剂
CN108420797B (zh) * 2018-05-09 2022-05-03 南京海融制药有限公司 维生素d类似物制剂及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4764378A (en) * 1986-02-10 1988-08-16 Zetachron, Inc. Buccal drug dosage form
DE3612212A1 (de) * 1986-04-11 1987-10-15 Basf Ag Verfahren zur herstellung von festen pharmazeutischen formen
DK0580860T4 (da) * 1991-04-16 2005-03-21 Nippon Shinyaku Co Ltd Fremgangsmåde til fremstilling af en fast dispersion
SG43179A1 (en) * 1991-12-18 1997-10-17 Warner Lambert Co A process for the prepatation of a solid dispersion
ES2145063T3 (es) * 1992-10-14 2000-07-01 Nippon Shinyaku Co Ltd Procedimiento de dislocacion del estado cristalino.
DE69332291T2 (de) * 1992-10-16 2003-07-31 Nippon Shinyaku Co Ltd Verfahren zur herstellung von wachsmatrizes
EP1123660A3 (de) * 1993-04-16 2004-01-07 McCORMICK & COMPANY, INC. Verkapselungszusammensetzungen

Also Published As

Publication number Publication date
EP0729748A4 (de) 1997-09-10
DE69432186T2 (de) 2004-05-06
EP0729748B1 (de) 2003-02-26
US5688510A (en) 1997-11-18
WO1995013794A1 (fr) 1995-05-26
EP0729748A1 (de) 1996-09-04

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Legal Events

Date Code Title Description
8332 No legal effect for de
8370 Indication of lapse of patent is to be deleted
8339 Ceased/non-payment of the annual fee