DE69430635D1 - Loteprednoletabonat-suspension - Google Patents

Loteprednoletabonat-suspension

Info

Publication number
DE69430635D1
DE69430635D1 DE69430635T DE69430635T DE69430635D1 DE 69430635 D1 DE69430635 D1 DE 69430635D1 DE 69430635 T DE69430635 T DE 69430635T DE 69430635 T DE69430635 T DE 69430635T DE 69430635 D1 DE69430635 D1 DE 69430635D1
Authority
DE
Germany
Prior art keywords
suspension
loteprednol etabonate
etabonate
loteprednol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69430635T
Other languages
English (en)
Other versions
DE69430635T2 (de
Inventor
Yaacov J Guy
Doron Friedman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bausch and Lomb Inc
Original Assignee
Pharmos Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US08/142,743 priority Critical patent/US5540930A/en
Application filed by Pharmos Corp filed Critical Pharmos Corp
Priority to PCT/US1994/012059 priority patent/WO1995011669A1/en
Application granted granted Critical
Publication of DE69430635D1 publication Critical patent/DE69430635D1/de
Publication of DE69430635T2 publication Critical patent/DE69430635T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • A61K31/787Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • A61K31/79Polymers of vinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or anti-inflammatory agents, e.g antirheumatic agents; Non-steroidal anti-inflammatory drugs (NSAIDs)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S514/00Drug, bio-affecting and body treating compositions
    • Y10S514/912Ophthalmic
    • Y10S514/914Inflammation
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S514/00Drug, bio-affecting and body treating compositions
    • Y10S514/937Dispersion or emulsion
DE69430635T 1993-10-25 1994-10-21 Loteprednoletabonat-suspension Expired - Lifetime DE69430635T2 (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US08/142,743 US5540930A (en) 1993-10-25 1993-10-25 Suspension of loteprednol etabonate for ear, eye, or nose treatment
PCT/US1994/012059 WO1995011669A1 (en) 1993-10-25 1994-10-21 Suspension of loteprednol etabonate

Publications (2)

Publication Number Publication Date
DE69430635D1 true DE69430635D1 (de) 2002-06-20
DE69430635T2 DE69430635T2 (de) 2003-01-02

Family

ID=22501105

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69430635T Expired - Lifetime DE69430635T2 (de) 1993-10-25 1994-10-21 Loteprednoletabonat-suspension

Country Status (17)

Country Link
US (2) US5540930A (de)
EP (1) EP0730443B1 (de)
JP (1) JP3570720B2 (de)
KR (1) KR100341497B1 (de)
AT (1) AT217523T (de)
AU (1) AU697617B2 (de)
BR (1) BR9407958A (de)
CA (1) CA2174550C (de)
DE (1) DE69430635T2 (de)
DK (1) DK0730443T3 (de)
ES (1) ES2179851T3 (de)
HU (1) HU227316B1 (de)
IL (1) IL111402A (de)
NZ (1) NZ275749A (de)
PT (1) PT730443E (de)
SG (1) SG48768A1 (de)
WO (1) WO1995011669A1 (de)

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AT217523T (de) 2002-06-15
NZ275749A (en) 1998-02-26
DE69430635T2 (de) 2003-01-02
EP0730443B1 (de) 2002-05-15
US5540930A (en) 1996-07-30
HU227316B1 (en) 2011-03-28
IL111402D0 (en) 1994-12-29
DK730443T3 (de)
CA2174550A1 (en) 1995-05-04
WO1995011669A1 (en) 1995-05-04
US5747061A (en) 1998-05-05
HU9601081D0 (en) 1996-06-28
KR100341497B1 (ko) 2002-12-05
JP3570720B2 (ja) 2004-09-29
CA2174550C (en) 2002-10-01
SG48768A1 (en) 1998-05-18
EP0730443A4 (de) 1997-11-05
IL111402A (en) 2000-12-06
AU697617B2 (en) 1998-10-15
BR9407958A (pt) 1996-11-26
AU7983594A (en) 1995-05-22
PT730443E (pt) 2002-11-29
DK0730443T3 (da) 2002-09-09
KR960705541A (ko) 1996-11-08
EP0730443A1 (de) 1996-09-11
HUT74882A (en) 1997-02-28
JPH09504294A (ja) 1997-04-28
ES2179851T3 (es) 2003-02-01

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